Numerical Study of Flow inside the Micro Fluidic Cell Sense Cartridge

Biosensor is a device which utilizes the biological element as a recognition element for the detection of analytes. The sample receiving unit is a critical integral part of the biosensor through which the sample is supplied to the biological element. In this study, the flow pattern inside the fluid cartridge was simulated using COMSOL multiphysics software with an objective of optimizing the shape and size of cartridge elements. The velocity distribution, flow induced shear stress and pressure drop were simulated as a single phase incompressible laminar flow under no slip condition. Influence of the shape and geometry of cartridge on flow patterns were studied by changing the shape and geometry of the cartridge. At a flow rate of 500 μl/min, the velocity and flow induced shear stress are in the range of 22 to 24 mm/sec and 0.76 to 0.85 N/m2 respectively.