Ammonium acetate catalyzed improved method for the regioselective conversion of olefins into halohydrins and haloethers at room temperature

An efficient and rapid method has been developed for the synthesis of vicinal bromo-/iodohydrins and β-bromo-/β-iodoethers from alkenes and N-bromo-/N-iodosuccinimides employing ammonium acetate (NH4OAc) in water or alcohols. The reaction takes place at room temperature within short reaction times and with excellent regioselectivity.

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