Optimization of biodiesel production by supercritical methyl acetate

► We studied optimum supercritical methyl acetate method in biodiesel production. ► Reaction temperature, pressure, time and molar ratio were the key parameters. ► Thermal decomposition, cis-trans isomerization and tocopherol content were checked. ► The highest yields were obtained at 350 °C/20 MPa/45 min/42 M ratio.