کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7144368 | 1462063 | 2016 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Label-free fiber optic biosensor based on thin-core modal interferometer
ترجمه فارسی عنوان
بیوسنسور فیبر نوری بدون برچسب بدون استفاده از تداخل سنجی مودال نازک
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
A label-free, cost-effective fiber optic biosensor (FOB) using electrostatic self-assembly (ESA) technology is presented and experimentally demonstrated. The FOB was constructed by sandwiching a thin-core single-mode fiber (TCSMF) between two single-mode fibers (SMFs). Firstly, we simulated the refractive index (RI) sensitivity of this fiber structure, and validated it using different concentrations of glycerol solutions. Then the diallyldimethyl ammonium chloride (PDDA) and styrenesulfonate sodium salt (PSS) were employed as polyelectrolyte self-assembled multilayers (PSAMs) deposition for surface functionalization of the fiber. We selected biotin-streptavidin as a bioconjugate pair for testing the effectiveness of the biosensor, and achieved a streptavidin detection limit of 0.02Â nM. The specificity was further verified by a comparison experiment conducted using bovine serum albumin (BSA) and gelatin. These results demonstrate the feasibility of this sensor for use in biological and chemical applications.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Sensors and Actuators B: Chemical - Volume 228, 2 June 2016, Pages 322-329
Journal: Sensors and Actuators B: Chemical - Volume 228, 2 June 2016, Pages 322-329
نویسندگان
Wenjie Yu, Tingting Lang, Jicheng Bian, Wen Kong,