کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7207116 | 1469064 | 2018 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Preparation and biocompatibility evaluation of polypropylene mesh coated with electrospinning membrane for pelvic defects repair
ترجمه فارسی عنوان
ارزیابی آمادگی و سازگاری با پلی پروپیلن مش با پوشش غشاء الکتروشیمیایی برای تعمیر ضایعات لگن
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
سایر رشته های مهندسی
مهندسی پزشکی
چکیده انگلیسی
Composite mesh with different materials composition could compensate for the drawbacks brought by single component mesh. Coating a membrane layer on the surface of macroporous mesh is a common method for preparing composite medical mesh. Electrospinning and dipping methods were introduced to form the two kinds of membrane-coated PP meshes (electro-mesh and dip-mesh); several properties were measured based on subcutaneous implantation model in rat. The results revealed that continuous tissue ingrowth could be observed for electro-mesh only with evidences of strength increase (electro-mesh: 0 week ââ¯13.1â¯Â±â¯0.88â¯N, 2 week ââ¯16.87â¯Â±â¯1.39â¯N, 4 week ââ¯22.04â¯Â±â¯2.05â¯N) and thickness increase (electro-mesh: 0 week ââ¯0.437â¯Â±â¯0.023â¯mm, 2 week ââ¯0.488â¯Â±â¯0.025â¯mm, 4 week ââ¯0.576â¯Â±â¯0.028â¯mm). However, no tissues were observed for dip-mesh in the first 2 weeks, both on macroscopic level and microscopic level, proved by strength data (dip-mesh: 0 week ââ¯13.36â¯Â±â¯1.06â¯N, 2 week ââ¯13.4â¯Â±â¯1.33â¯N, 4 week - 18.61â¯Â±â¯1.89â¯N) and thickness data (dip-mesh: 0 week ââ¯0.439â¯Â±â¯0.018â¯mm, 2 week ââ¯0.439â¯Â±â¯0.019â¯mm, 4 week ââ¯0.502â¯Â±â¯0.032â¯mm). Electro-mesh had larger surface area decrease (10.74â¯Â±â¯1.22%) than that of dip-mesh (2.78â¯Â±â¯0.52%). The adhesion level of electro-mesh (medium adhesion) was also higher than that of dip-mesh (mild adhesion). Even if showing differences in several properties, both meshes were similar under histological observation, with the ability to support fresh tissues ingrowth. Considering operation environment, electro-mesh seems more suitable than dip-mesh with a rapid tissue growing, medium adhesion rate for repairing pelvic floor defects.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the Mechanical Behavior of Biomedical Materials - Volume 81, May 2018, Pages 142-148
Journal: Journal of the Mechanical Behavior of Biomedical Materials - Volume 81, May 2018, Pages 142-148
نویسندگان
Yao Lu, Shaoju Fu, Shuanglin Zhou, Ge Chen, Chaoting Zhu, Nannan Li, Ying Ma,