Clinical predictive factors associated with pathologic complete response in locally advanced rectal cancer

No smoking history, cN-, tumor size of ≤5 cm, well-differentiated tumor, pre-nCRT CEA level of ≤5 (ng/mL) and median interval to surgery of >8 weeks were independent clinical predictors for pCR in rectal cancer patients treated with long course of nCRT. This factors may help clinicians predict the prognosis of patients and develop proper treatment approach.