کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7624043 | 1494547 | 2015 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Intake of Passiflora edulis leaf extract improves antioxidant and anti-inflammatory status in rats with 2,4,6-trinitrobenzenesulphonic acid induced colitis
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
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چکیده انگلیسی
The antioxidant and anti-inflammatory effects of the aqueous extract of Passiflora edulis leaves, which is a source of vitexin, isovitexin and isoorientin, was investigated in a 2,4,6-trinitrobenzenesulphonic acid induced colitis model. The oral intake of P. edulis extract (1100âµgâmLâ1) improved significantly (Pâ<â0.05) the endogenous antioxidant status and decreased lipid peroxidation in serum, liver, and colon. The consumption of P. edulis extract decreased the level of pro-inflammatory in colon tissue, especially by reducing IL-1β five-fold and TNF-α two-fold compared to the control colitis group. The extract of P. edulis leaves possessed therapeutic activity in healthy rats and in TNBS-induced colitis, especially by controlling the oxidative stress and inflammation observed in this disease.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Functional Foods - Volume 17, August 2015, Pages 575-586
Journal: Journal of Functional Foods - Volume 17, August 2015, Pages 575-586
نویسندگان
Cinthia Baú Betim Cazarin, Juliana Kelly da Silva, Talita Cristina Colomeu, Ãngela Giovana Batista, Laura Maria Molina Meletti, Jonas Augusto Rizzato Paschoal, Stanislau Bogusz Junior, PatrÃcia Aparecida de Campos Braga, Felix Guillermo Reyes Reyes,