Detection of sibutramine in adulterated dietary supplements using attenuated total reflectance-infrared spectroscopy

- ATR-IR spectra were recorded for 125 dietary supplements suspected of containing sibutramine.
- ATR-IR spectra were related to the presence of sibutramine using chemometrics.
- A k-NN model was able to discriminate between positive and negative samples.
- Detection of sibutramine is possible in dosage of 3 mg in 20 g of product.