Synthesis, molecular structure, DNA interaction and antioxidant activity of novel naphthoxazole compound

A novel naphthoxazole compound was synthesized and characterized. The crystal structure of the compound shows that N atom locates at β-position and oxygen atom at α-position in naphthalene cycle. The DNA binding behaviors were investigated. The pBR322 DNA cleavage induced by the compound was studied. The antioxidant activity of the compound against hydroxyl radical was also explored.