A new 14-membered tetraazamacrocycle-bonded silica stationary phase for reversed-phase high-performance liquid chromatography

► A 14-membered tetraazamacrocycle-based HPLC stationary phase was prepared. ► The new phase was successfully evaluated by the LSER method. ► Separations of four sets of various analytes were accomplished on the new phase. ► Multiple-function mechanism can be offered by the new stationary phase.