Comparative study of some polyphenols in Plantago species

► First characterization of endemic species Plantago reniformis and Plantago schwarzenbergiana regarding flavonoid profile. ► First study to determine acteoside and flavonoids in several Plantago species. ► Plantago lanceolata contained the highest concentration of acteoside. ► Plantago holosteum was richest in flavonoids. ► Mangiferin is detected in Plantago species for the first time.