کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7781094 | 1500558 | 2018 | 17 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A light-weight and high-efficacy antibacterial nanocellulose-based sponge via covalent immobilization of gentamicin
ترجمه فارسی عنوان
یک اسفنج ضد باکتری بر پایه نانو سلولز سبک و با کارایی بالا با استفاده از جنتامایسین
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کلمات کلیدی
ضد باکتری، نانو فیبرهای سلولز، اسفنج پیوند شیمیایی، جنتامایسین،
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
چکیده انگلیسی
Covalent grafting of gentamicin to nanocellulose-based sponge was realized for the first time. The named sponge was prepared by initially multi-crosslinking among cellulose nanofibers (CNF), cellulose acetoacetate (CAA) and 3-aminopropyl(triethoxy)silane (APTES) followed by surface modification with gentamicin via the formation of enamine bond. The structure and mechanical performances of the obtained gentamicin-functionalized CNF sponge were characterized with FT-IR, XPS, EDX, SEM, Nitrogen adsorption-desorption measurement, and compressive test. Its antibacterial activity against E. coli and S. aureus was evaluated using disc diffusion and colony forming units (CFU) count methods. The results showed that gentamicin was successfully grafted on the surface of CNF sponges without significant change in morphology and slight improvement in mechanical performance. The superior lightness of the sponge (0.0174âg cmâ3) was demonstrated by showing the sponge could be supported by a flower branch without crushing it. Gentamicin-functionalized CNF sponges showed excellent antibacterial performance against E. coli and S. aureus, with bactericidal rates of over 99.9%.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Polymers - Volume 200, 15 November 2018, Pages 595-601
Journal: Carbohydrate Polymers - Volume 200, 15 November 2018, Pages 595-601
نویسندگان
Yongmei Xiao, Liduo Rong, Bijia Wang, Zhiping Mao, Hong Xu, Yi Zhong, Linping Zhang, Xiaofeng Sui,