Synthesis, biological evaluation and molecular modeling of novel azaspiro dihydrotriazines as influenza virus inhibitors targeting the host factor dihydrofolate reductase (DHFR)

Synthesis, biological evaluation and molecular modeling of novel azaspiro dihydrotriazines as influenza virus inhibitors targeting the host factor dihydrofolate reductase (DHFR)

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 155, 15 July 2018, Pages 229-243

Valeria Francesconi, Luca Giovannini, Matteo Santucci, Elena Cichero, Maria Paola Costi, Lieve Naesens, Fabrizio Giordanetto, Michele Tonelli,