Synergistic effect of strontium and silicon in strontium-substituted sub-micron bioactive glass for enhanced osteogenesis

This work investigated the underlying molecular mechanisms of the enhanced proliferation and osteogenic differentiation of Sr-SBG on mMSCs. The results demonstrated that Wnt/β-catenin and NFATc signaling pathway synergistically mediated the enhanced effect induced by Sr-SBG.216