A new approach to studies of non-linear dynamics of kinks activated in inhomogeneous polynucleotide chains

A new approach has been proposed to study the non-linear dynamics of local conformational distortions (kinks) activated in DNA polynucleotide chains that are inhomogeneous. The dependence of the dynamic characteristics of kinks on the chain composition has been obtained. The result has been applied to estimate the size, energy, density of energy, and velocity of kinks activated in chains having the binary sequence or the sequence similar to the sequences of promoters A1, A2, and A3 of the bacteriophage T7 genome.