کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
810515 1469090 2016 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The effect of lubricant constituents on lubrication mechanisms in hip joint replacements
ترجمه فارسی عنوان
اثر اجزای روان کننده بر مکانیزم های روانکاری در جایگزینی مفصلی مفصل ران
کلمات کلیدی
جایگزین هیپ، میکروسکوپ فلورسنت، تداخل سنجی رنگی، آلبومین، γ-گلوبولین، ضخامت فیلم روان کننده
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی پزشکی
چکیده انگلیسی


• Novel methodological approach for description of protein lubrication mechanisms.
• Combination of the optical interferometry with fluorescent microscopy.
• Assessment of the role of particular proteins while the presence of another protein.
• Protein film thickness development under various operating conditions.
• Significant influence of operating conditions on protein film lubrication.

The aim of the present paper is to provide a novel experimental approach enabling to assess the thickness of lubricant film within hip prostheses in meaning of the contribution of particular proteins. Thin film colorimetric interferometry was combined with fluorescent microscopy finding that a combination of optical methods can help to better understand the interfacial lubrication processes in hip replacements. The contact of metal femoral head against a glass disc was investigated under various operating conditions. As a test lubricant, the saline solution containing the albumin and γ-globulin in a concentration 2:1 was employed. Two different mean speeds were applied, 5.7 and 22 mm/s, respectively. The measurements were carried out under pure rolling, partial negative and partial positive sliding conditions showing that kinematic conditions substantially affects the formation of protein film. Under pure rolling conditions, an increasing tendency of lubricant film independently on rolling speed was detected, while the total thickness of lubricant film can be attributed mainly to albumin. When the ball was faster than the disc (negative sliding), a very thin lubricant film was observed for lower speed with no significant effect of particular proteins. The increase in sliding speed led to the increase of film thickness mainly caused due to the presence of γ-globulin. On the contrary, when the disc was faster than the ball (positive sliding), the film formation was very complex and time dependent while both of the studied proteins have shown any qualitative change during the test, however the effect of albumin seems to be much more important. Since a very good agreement of the results was obtained, it can be concluded that the approach consisting of two optical methods can provide the fundamental information about the lubricant film formation in meaning of particular proteins while the simultaneous presence of other constituents in model synovial fluid.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the Mechanical Behavior of Biomedical Materials - Volume 55, March 2016, Pages 295–307
نویسندگان
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