Phenotype analyses of IL-10-producing Foxp3− CD4+ T cells increased by subcutaneous immunotherapy in allergic airway inflammation

We successfully developed an airway allergic model for SCIT. It was suggested that most of IL-10-producing Foxp3− CD4+ regulatory T cells increased by SCIT in the lungs were CD49b+ CD4+ regulatory T cells, but neither Th2 cells nor Tr1 cells.