کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8553940 | 1562697 | 2018 | 33 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Cell wall damage and oxidative stress in Candida albicans ATCC10231 and Aspergillus niger caused by palladium nanoparticles
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
بهداشت، سم شناسی و جهش زایی
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چکیده انگلیسی
In this work the toxic effect of Palladium nanoparticles (PdNPs) was investigated in two eukaryotic cell models, Candida albicans and Aspergillus niger. PdNPs were synthesized by chemical reduction method, obtaining spherical NPs with a primary size ranging from 3 to 15â¯nm. PdNPs showed a hydrodynamic size of 1548â¯nm in Lee's minimum media. Minimal inhibitory concentration was determined at 200 and 250â¯ppm for Candida albicans and Aspergillus niger respectively, revealing a significant cell growth inhibition (ANOVA and tukey analysis, αâ¯=â¯0.5). Reactive Oxygen Species levels were increased in both microorganisms. Confocal, scanning and transmission electron microscopy studies revealed cell wall damage and cellular morphology changes, induced by the interaction of PdNPs, in both microorganisms.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Toxicology in Vitro - Volume 48, April 2018, Pages 111-120
Journal: Toxicology in Vitro - Volume 48, April 2018, Pages 111-120
نویسندگان
Martha Samira Athie-GarcÃa, Hilda Amelia Piñón-Castillo, Laila Nayzzel Muñoz-Castellanos, Ana Laura Ulloa-Ogaz, Perla Ivonne MartÃnez-Varela, Armando Quintero-Ramos, Robert Duran, José Guadalupe Murillo-Ramirez, Erasmo Orrantia-Borunda,