کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8682187 | 1579710 | 2018 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Motor unit number estimation (MUNE): Where are we now?
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کلمات کلیدی
CMAPSIPMUNEMotor unit number indexconcentric needle EMGspinal muscular atrophy - آتروفی عضلانی نخاعیamyotrophic lateral sclerosis - اسکلروز جانبی آمیوتروفیکmotor unit number estimation - برآورد تعداد واحد موتورALS - بیماری اسکلروز جانبی آمیوتروفیکSMA - دبیرستانMUNIX - مونیکسMotor unit - واحد موتورcompound muscle action potential - پتانسیل عمل عضله مرکبQuantification - کوانتومی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
عصب شناسی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Estimation of the number of motor units (MUNE) in specific muscles is important to monitor outcome in progressive neurogenic disorders, with potential application in clinical trials. However, in spite of recent developments to identify the most convenient technique for MUNE, all current methods have individual shortcomings. It is essential to understand the scientific concepts that support MUNE and the many methods already proposed. In particular, the core role of the compound muscle action potential (CMAP) size in the estimation process is undervalued. Operator-dependent variation in CMAP amplitude or area is the main factor underlying MUNE stability. At present, MUNIX, as standardized in many centers, is probably the best accepted method. Future developments should be based on full understanding of the neurophysiological concepts underlying the MUNE calculation, in order to find a quick, well-tolerated, operator-friendly and reliable method to apply more universally in clinical practice.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Neurophysiology - Volume 129, Issue 8, August 2018, Pages 1507-1516
Journal: Clinical Neurophysiology - Volume 129, Issue 8, August 2018, Pages 1507-1516
نویسندگان
Mamede de Carvalho, Paul E. Barkhaus, Sanjeev D. Nandedkar, Michael Swash,