کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8842574 | 1615775 | 2017 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Contribution of flagella and motility to gut colonisation and pathogenicity of Salmonella Enteritidis in the chicken
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موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
میکروبیولوژی و بیوتکنولوژی کاربردی
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چکیده انگلیسی
Salmonella Enteritidis causes fowl paratyphoid in poultry and is frequently associated to outbreaks of food-borne diseases in humans. The role of flagella and flagella-mediated motility into host-pathogen interplay is not fully understood and requires further investigation. In this study, one-day-old chickens were challenged orally with a wild-type strain Salmonella Enteritidis, a non-motile but fully flagellated (SE ÎmotB) or non-flagellated (SE ÎfliC) strain to evaluate their ability to colonise the intestine and spread systemically and also of eliciting gross and histopathological changes. SE ÎmotB and SE ÎfliC were recovered in significantly lower numbers from caecal contents in comparison with Salmonella Enteritidis at early stages of infection (3 and 5Â dpi). The SE ÎmotB strain, which synthesises paralysed flagella, showed poorer intestinal colonisation ability than the non-flagellated SE ÎfliC. Histopathological analyses demonstrated that the flagellated strains induced more intense lymphoid reactivity in liver, ileum and caeca. Thus, in the present study the flagellar structure and motility seemed to play a role in the early stages of the intestinal colonisation by Salmonella Enteritidis in the chicken.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brazilian Journal of Microbiology - Volume 48, Issue 4, OctoberâDecember 2017, Pages 754-759
Journal: Brazilian Journal of Microbiology - Volume 48, Issue 4, OctoberâDecember 2017, Pages 754-759
نویسندگان
Fernanda de Oliveira Barbosa, Oliveiro Caetano de Freitas Neto, Diego Felipe Alves Batista, Adriana Maria de Almeida, Marcela da Silva Rubio, Lucas Bocchini Rodrigues Alves, Rosemeire de Oliveira Vasconcelos, Paul Andrew Barrow, Angelo Berchieri Junior,