کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8960739 | 1646430 | 2018 | 48 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Effectiveness of depression interventions for people living with HIV in Sub-Saharan Africa: A systematic review & meta-analysis of psychological & immunological outcomes
ترجمه فارسی عنوان
اثربخشی مداخلات افسردگی برای افراد مبتلا به اچ آی وی در کشورهای جنوب صحرای آفریقا: یک بررسی منظم و متاآنالیز نتایج روانشناختی و ایمنی
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
چکیده انگلیسی
This meta-analytic review evaluated the effectiveness of depression interventions on the psychological and immunological outcomes of people living with HIV in sub-Saharan Africa. 14 studies, yielding 932 participants were eligible. A random-effects models indicated that depression interventions were followed by large reductions in depression scores (effect sizeâ¯=â¯1.86, 95% CIâ¯=â¯1.71, 2.01, pâ¯<â¯0.01). No significant effect on immune outcome was observed, however there was a trend toward immune improvement of medium effect size (effect size on CD4 count and/or viral suppressionâ¯=â¯0.57, 95% CIâ¯=â¯â0.06, 1.20, pâ¯=â¯0.08). Pharmacological interventions appeared to have a significantly larger improvement in depression scores than psychological interventions. The greatest improvement in immune status was demonstrated in psychological treatments which incorporated a component to enhance HIV medication adherence, however these results did not reach significance. Small sample sizes and highly heterogeneous analysis necessitate caution in interpretation. The results of this meta-analysis should thus be treated as preliminary evidence and used to encourage further studies of immunopsychiatry in HIV in sub-Saharan Africa.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain, Behavior, and Immunity - Volume 73, October 2018, Pages 261-273
Journal: Brain, Behavior, and Immunity - Volume 73, October 2018, Pages 261-273
نویسندگان
Ruth Verity Passchier, Melanie Amna Abas, Ikenna D. Ebuenyi, Carmine M. Pariante,