کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8998252 1115614 2005 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Brain mitochondrial injury induced by oxidative stress-related events is prevented by tamoxifen
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
Brain mitochondrial injury induced by oxidative stress-related events is prevented by tamoxifen
چکیده انگلیسی
These results show that tamoxifen can afford protection against brain mitochondrial injury promoted by several oxidative stress-related events such as hydrogen peroxide production, lipid peroxidation and the induction of the MPT. Since numerous neurodegenerative diseases are intimately related with mitochondrial dysfunction, future therapeutical strategies could be designed taking into account this protective role of tamoxifen.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuropharmacology - Volume 48, Issue 3, March 2005, Pages 435-447
نویسندگان
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