کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9191192 | 1579955 | 2005 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Lack of association between variations in the brain-derived neurotrophic factor (BDNF) gene and temporal lobe epilepsy
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
عصب شناسی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Recently, an association between the C240T polymorphism in the brain-derived neurotrophic factor (BDNF) gene and partial epilepsy was demonstrated in a Japanese population. In this study we attempted to replicate the initial finding in a patient-control population of European ancestry and in addition tested whether the functional Val66Met polymorphism is associated with temporal lobe epilepsy (TLE). Genotypes of 151 TLE patients and 189 controls did not differ significantly for either of the variations. Results suggest that neither of the studied polymorphisms are strong susceptibility factors for TLE in this sample of individuals of European ancestry.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Epilepsy Research - Volume 66, Issues 1â3, AugustâSeptember 2005, Pages 59-62
Journal: Epilepsy Research - Volume 66, Issues 1â3, AugustâSeptember 2005, Pages 59-62
نویسندگان
Falk W. Lohoff, Thomas N. Ferraro, John P. Dahl, Marie A. Hildebrandt, Theresa M. Scattergood, Michael J. O'Connor, Michael R. Sperling, Dennis J. Dlugos, Wade H. Berrettini, Russell J. Buono,