کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9277954 | 1593090 | 2005 | 13 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Functional genome of the human pathogenic fungus Paracoccidioides brasiliensis
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Paracoccidioides brasiliensis is a dimorphic and thermo-regulated fungus which is the causative agent of paracoccidioidomycosis, an endemic disease widespread in Latin America. Pathogenicity is assumed to be a consequence of the cellular differentiation process that this fungus undergoes from mycelium to yeast cells during human infection. In an effort to elucidate the molecular mechanisms involved in this process a network of Brazilian laboratories carried out a transcriptome project for both cell types. This review focuses on the data analysis yielding a comprehensive view of the fungal metabolism and the molecular adaptations during dimorphism in P. brasiliensis from analysis of 6022 groups, related to expressed genes, which were generated from both mycelium and yeast phases.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: FEMS Immunology and Medical Microbiology - Volume 45, Issue 3, 1 September 2005, Pages 369-381
Journal: FEMS Immunology and Medical Microbiology - Volume 45, Issue 3, 1 September 2005, Pages 369-381
نویسندگان
Maria Sueli S. Felipe, Fernando A.G. Torres, Andrea Q. Maranhão, Ildinete Silva-Pereira, Marcio J. Poças-Fonseca, Elida G. Campos, LÃdia M.P. Moraes, FabrÃcio B.M. Arraes, Maria José A. Carvalho, Rosângela V. Andrade, André M. Nicola,