Keywords: E171; Titanium dioxide; Nanoparticles; Vasoconstriction; Endothelial dysfunction; 5-HT; 5-hydroxytryptamine; 5-HT1B; 5-hydroxytryptamine receptor 1B; 5-HT2A; 5-hydroxytryptamine receptor 2A; EDNRA; endothelin receptor A; EDNRB; endothelin receptor B; ICAM
مقالات ISI (ترجمه نشده)
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Keywords: Dopamine; Serotonin; Obesity; Neuroimaging; Humans; 5-HT1A,B; serotonin 1A and 1B receptor; 5-HT2A; serotonin 2A receptor; 5-HT2C; serotonin 2C receptor; 5-HT4; serotonin 4 receptor; Bmax; receptor or transporter availability; BMI; body mass index; BP; bi
Keywords: AUD; Alcohol use disorder; FDA; Food and Drug Administration; MOR; Mu opioid receptor; DOR; Delta opioid receptor; KOR; Kappa opioid receptor; NMDA; N-methyl-d-aspartate; GABA; Gaba amino butyric acid; DSM-IV; Diagnostic and statistical measurement IV; PA
Keywords: Inverse agonist; Antagonist; Serotonin; 5-HT2A;
Keywords: 5-HT2A; CYP2D6; DRD2; Genetic polymorphism; Risperidone; Schizophrenia;
Keywords: Genetics; Obsessive-compulsive disorder; OCD; Serotonin system; Neuropsychiatry; Neuroscience; Psychiatry; Candidate gene; Genetic association; Serotonin transporter; SLC6A4; 5-HTTLPR; HTR2A; 5-HT2A; HTR1B; 5-HT1B; HTR2C; 5-HT2C; Subtypes; Symptom dimensi
Keywords: D2; 5-HT1A; 5-HT2A; PCP-induced hyperactivity; Catalepsy
Keywords: schizophrenia; mGlu2R; 5-HT2A; PAMs; HDAC2; epigenetics;
Keywords: 5-HT2a; 5-hydroxytryptamine receptor, type 2a; ABMD; adiabatic bias molecular dynamics; AMBER; assisted model building with energy refinement program; BPTI; bovine pancreatic trypsin inhibitor; COX; cyclooxygenase; CPU; central processing unit; CV; collec
Keywords: Antidepressant; Benzoxazole/benzothiazole; 2,3-Dihydrobenzo[b][1,4]dioxine; 5-HT1A; 5-HT2A;
Keywords: 5-HT2A; 5-HT2B; CNS; Tris-(phenylalkyl)amine
Influence of intertrial interval on basal and drug-induced impulsive action in the 5-choice serial reaction time task: Effects of d-amphetamine and (±)-2,5-dimethoxy-4-iodoamphetamine (DOI)
Keywords: 5-HT2A; 5-hydroxytryptamine 2A receptor; 5-CSRTT; 5-choice serial reaction time task; AMPH; dextroamphetamine; DOI; (±) 2,5-dimethoxy-4-iodoamphetamine; ITI; intertrial interval; Impulsivity; 5-CSRTT; Attention; Amphetamine; 5-HT2A receptor agonist;
Anti-aggregation effect of aroxyalkyl derivatives of 2-methoxyphenylpiperazine is due to their 5-HT2A and α2-adrenoceptor antagonistic properties. A comparison with ketanserin, sarpogrelate, prazosin, yohimbine and ARC239
Keywords: Serotonin hydrochloride (PubChem CID: 160436); ARC239 (PubChem CID: 609483); Sarpogrelate hydrochloride (PubChem CID: 444005); Yohimbine hydrochloride (PubChem CID: 6169); Ketanserin tartrate (PubChem CID: 16219944); (±)-Epinephrine hydrochloride (PubChe
Activation of 5-HT2A Receptors Restores KCC2 Function and Reduces Neuropathic Pain after Spinal Cord Injury
Keywords: DIOA; [(dihydroindenyl)oxy]alkanoic acid; DRG; dorsal root ganglia; KCC2; potassium chloride cotransporter type 2; SCI; spinal cord injury; SNI; spared nerve injury; TCB-2; (4-bromo-3,6-dimethoxybenzocyclobuten-1-yl)methylamine hydrobromide; spinal cord i
Serotonergic hallucinogens in the treatment of anxiety and depression in patients suffering from a life-threatening disease: A systematic review
Keywords: Hallucinogen; LSD; Psilocybin; Anxiety; Life-threatening disease; Cancer; 5HT; 5-hydroxytryptamine (=Â serotonin); 5-HT2A; 5-hydroxytryptamine (serotonin) receptor 2A; ASC; altered states of consciousness; BDI; Beck Depression Inventory; DMT; N,N-dimethyl
5-HT2A-mGlu2/3 receptor complex in rat spinal cord glutamatergic nerve endings: A 5-HT2A to mGlu2/3 signalling to amplify presynaptic mechanism of auto-control of glutamate exocytosis
Keywords: mGlu2/3 receptor; 5-HT2A receptor; Glutamate release; Spinal cord; GPCR crosstalk; Heterocomplex; mGlu2/3; metabotropic glutamate receptor type 2/3; 5-HT2A; serotonin type 2A; [3H]D-Asp; [3H]D-aspartate; CNS; central nervous system; EPSCs; excitatory post
PDZ domain containing protein 1 (PDZK1), a modulator of membrane proteins, is regulated by the nuclear receptor THRβ
Keywords: Thyroid hormones; Scaffold protein; PDZ-domain; Gene regulation; Thyroid hormone receptors; 5-HT2A; Serotonin 2A receptor; ABC; ATP-binding cassette transporter; AhR; Transcription factor aryl hydrocarbon receptor; BCRP; Breast cancer resistance protein;
Chronic methamphetamine self-administration dysregulates 5-HT2A and mGlu2 receptor expression in the rat prefrontal and perirhinal cortex: Comparison to chronic phencyclidine and MK-801
Keywords: Methamphetamine; Phencyclidine; MK-801; Heterocomplex; mGlu2; 5-HT2A;
Modality selective roles of pro-nociceptive spinal 5-HT2A and 5-HT3 receptors in normal and neuropathic states
Keywords: In vivo electrophysiology; Ventral posterolateral thalamus; Spinal nerve ligation; Neuropathic pain; Descending facilitation; Serotonergic pain modulation; Ondansetron; Ketanserin; 5-HT2A; 5-HT3; CPM; conditioned pain modulation; R; receptor; RM; repeated
Selective serotonin reuptake inhibitors affect structure, function and metabolism of skeletal muscle: A systematic review
Keywords: Serotonin (Pubchem CID: 5202); Fluoxetine (Pubchem CID: 3386); Citalopram (Pubchem CID: 2771); Escitalopram (Pubchem CID:146570); Fluvoxamine (Pubchem CID: 5324346); Dexamethasone (Pubchem CID: 5743); Insulin (Pubchem CID:70678557); SSRIs; selective serot
Fluoxetine and its active metabolite norfluoxetine disrupt estrogen synthesis in a co-culture model of the feto-placental unit
Keywords: Selective serotonin-reuptake inhibitors (SSRI); Aromatase (CYP19); Serotonin transporter (SERT); 5-HT2A receptor; Feto-placental steroidogenesis; Human; 5-HT; 5-hydroxytryptamine, serotonin; 5-HT2A; 5-HT receptor type 2A; ANOVA; one-way analysis of varian
Serotonin 2A receptor (5-HT2A) gene promoter variant interacts with chronic perceived stress to modulate resting parasympathetic activity in humans
Keywords: 5-HT2A; serotonin 2A receptor; ANS; autonomic nervous system; BAI; Beck Anxiety Inventory; BDI; Beck Depression Inventory-II; BMI; body mass index; CVDs; cardiovascular diseases; DBP; diastolic blood pressure; ECG; electrocardiogram; HF; high frequency po
Estrogen receptor β deficiency impairs BDNF-5-HT2A signaling in the hippocampus of female brain: A possible mechanism for menopausal depression
Keywords: Menopausal depression; Estrogen receptor β (ERβ); Brain-derived neurotrophic factor (BDNF); 5-HT1A; 5-HT2A; Hippocampus;
Sedative effect of Clozapine is a function of 5-HT2A and environmental novelty
Keywords: 5-HT2A; Clozapine; Environmental novelty; Knockout;
Clozapine as the most efficacious antipsychotic for activating ERK 1/2 kinases: Role of 5-HT2A receptor agonism
Keywords: Antipsychotics; Clozapine; ERK1/2; AKT; 5-HT2A; Biased agonism;
Extrinsic nerves are not involved in branchial 5-HT dynamics or pulsatile urea excretion in Gulf toadfish, Opsanus beta
Keywords: 5-HT; 5-HIAA; Vagus; Glossopharyngeal; Gills; tUT; SERT; 5-HT2A;
Association study of 5-HT1A, 5-HT2A polymorphisms with schizophrenia and major depressive disorder in the Han Chinese population
Keywords: Association; 5-HT1A; 5-HT2A; Schizophrenia; Major depressive disorder;
Effects of 7-day repeated treatment with the 5-HT2A inverse agonist/antagonist pimavanserin on methamphetamine vs. food choice in male rhesus monkeys
Keywords: Methamphetamine; Choice; Rhesus monkey; 5-HT2A; Addiction; Pimavanserin;
Antidepressant-like activity of aroxyalkyl derivatives of 2-methoxyphenylpiperazine and evidence for the involvement of serotonin receptor subtypes in their mechanism of action
Keywords: Depression; Serotonin; 5-HT1A; 5-HT2A; 5-HT3; 5-HT7; 2-methoxyphenylpiperazine; Forced swim test
Psychedelics Recruit Multiple Cellular Types and Produce Complex Transcriptional Responses Within the Brain
Keywords: Neurons; Glia; Astrocytes; Psychedelics; Gene expression; mPFC; Serotonin; Immunofluorescence; FACS; Neurocytometry; 5-HT2A;
C4 phenyl aporphines with selective h5-HT2B receptor affinity
Keywords: 5-HT2A; 5-HT2B; Aporphine; CNS; Nantenine
Synthesis and evaluation of aporphine analogs containing C1 allyl isosteres at the h5-HT2A receptor
Keywords: Aporphine; 5-HT2A; Antagonist; Adrenergic; Nantenine;
Synthesis and biological evaluation of 4-nitroindole derivatives as 5-HT2A receptor antagonists
Keywords: 4-Nitroindole; Sulfonamides; Methyleneamino-N,N-dimethylformamidine group; 5-HT2A; 5-HT2C; 5-HT6 receptor
Activation of serotonin 5-HT7 receptor induces coronary flow increase in isolated rat heart
Keywords: 5-HT, 5-hydroxytryptamine; NO, nitric oxide; NOS, nitric oxide synthase; l-NAME, Nω-Nitro-l-arginine methyl ester hydrochlorideSerotonin; 5-HT7; 5-HT2A; Coronary flow; Nitric oxide
Research reportCombined serotonin (5-HT)1A agonism, 5-HT2A and dopamine D2 receptor antagonism reproduces atypical antipsychotic drug effects on phencyclidine-impaired novel object recognition in rats
Keywords: NOR; 5-HT1A; 5-HT2A; D2; Antipsychotic; Phencyclidine;
Effect of ketamine on the regional cerebral blood flow and binding index of the 5-HT2A receptor radioligand 123I-R91150 in the canine brain
Keywords: ketamine; mood disorders; brain perfusion; serotonin; 5-HT2A; SPECT;
Maternal lipopolysaccharide treatment differentially affects 5-HT2A and mGlu2/3 receptor function in the adult male and female rat offspring
Keywords: Maternal infection; 5-HT2A; mGlu2/3; PPI; Schizophrenia; 5-HT; 5-hydroxytryptamine; ANOVA; analysis of variance; ASR; acoustic startle response; BLA; basolateral amygdala; CeA; central nucleus of amygdala; DOI; (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminop
Evaluation of structural effects on 5-HT2A receptor antagonism by aporphines: Identification of a new aporphine with 5-HT2A antagonist activity
Keywords: Aporphine; Nantenine; 5-HT2A; α1A; Antagonist; Structure-activity relationship (SAR);
The effect of prolonged exposure to morphine on canine cerebral 5-HT2A receptors measured with 123I-R91150 SPECT
Keywords: 5-HT2A; Morphine; 123I-R91150; SPECT; Dogs;
Effects of the hallucinogen 2,5-dimethoxy-4-iodophenethylamine (2C-I) and superpotent N-benzyl derivatives on the head twitch response
Keywords: Psychedelic; 5-HT2A; Head twitch; LSD;
Postnatal Fluoxetine-Evoked Anxiety Is Prevented by Concomitant 5-HT2A/C Receptor Blockade and Mimicked by Postnatal 5-HT2A/C Receptor Stimulation
Keywords: Antidepressant; DOI; 5-HT1A; 5-HT2A; 5-HT2C; ketanserin; Prozac; SSRI; WAY-100635
Characterization of [11C]Cimbi-36 as an agonist PET radioligand for the 5-HT2A and 5-HT2C receptors in the nonhuman primate brain
Keywords: 5-HT2A; 5-HT2C; [11C]Cimbi-36; Agonist; Monkey; Serotonin receptors;
Cannabinoid-induced upregulation of serotonin 2A receptors in the hypothalamic paraventricular nucleus and anxiety-like behaviors in rats
Keywords: 5-HT; 5-hydroxytryptamine; 5-HT2A; serotonin 2A; Î9-THC; Î9-tetrahydrocannabinol; ERK; extracellular kinase; PVN; hypothalamic paraventricular nucleus; CP 55,940; (â)-cis-3-[2-hydroxy-4-(1,1-dimethylheptyl)phenyl]-trans-4-(3-hydroxypropyl)cyclohexanol
Multiple Regulatory Variants Modulate Expression of 5-Hydroxytryptamine 2A Receptors in Human Cortex
Keywords: 5-HT2A; depression; HTR2A; mRNA expression; schizophrenia; serotonin;
Research reportDifferent MK-801 administration schedules induce mild to severe learning impairments in an operant conditioning task: Role of buspirone and risperidone in ameliorating these cognitive deficits
Keywords: PFC; prefrontal cortex; NMDA; N-methyl-d-aspartate; NMDAR; N-methyl-d-aspartate receptor; 5-HT2A; serotonin receptor 2A; 5-HT1A; serotonin receptor 1A; D2R; dopamine receptor 2; P7; postnatal day 7; P11; postnatal day 11; Operant conditioning; Prefrontal
The two faces of the pharmacological interaction of mGlu2 and 5-HT2A - Relevance of receptor heterocomplexes and interaction through functional brain pathways
Keywords: G-protein coupled receptor; GPCR; Metabotropic glutamate receptor 2 (mGlu2); 5-Hydroxytryptamine receptor 2A (5-HT2A); Heteromerization; Functional receptor interaction; Receptor cross-talk; Schizophrenia; 5-HT; 5-hydroxytryptamine; 5-HT2A; serotonin rece
Microglial activation, increased TNF and SERT expression in the prefrontal cortex define stress-altered behaviour in mice susceptible to anhedonia
Keywords: Chronic stress; Anhedonia; TNF; SERT; 5-HT2A;
Antagonizing 5-HT2A receptors with M100907 and stimulating 5-HT2C receptors with Ro60-0175 blocks cocaine-induced locomotion and zif268 mRNA expression in Sprague-Dawley rats
Keywords: Serotonin; Cocaine; Zif; 5-HT2A; 5-HT2C; Locomotor
Synthesis and pharmacological evaluation of new N-phenylpiperazine derivatives designed as homologues of the antipsychotic lead compound LASSBio-579
Keywords: Schizophrenia; Antipsychotics; N-Phenylpiperazine; LASSBio-579; Homologation; 5-HT2A
New 8-aminoalkyl derivatives of purine-2,6-dione with arylalkyl, allyl or propynyl substituents in position 7, their 5-HT1A, 5-HT2A, and 5-HT7 receptor affinity and pharmacological evaluation
Keywords: purine-2,6-diones; 5-HT1A; 5-HT2A; 5-HT7 receptor ligands; depression; forced swim test; anxiety; four-plate test