Keywords: Autotaxin; Bile salt; Cholestasis; Liver; Lysophosphatidic acid; Management; Pruritus;
مقالات ISI (ترجمه نشده)
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Keywords: Isocyanate; Toluene Diisocyanate; Autotaxin; Lysophosphatidic Acid; Respiratory Sensitizer; Purinergic Receptors; Interleukin 1β; Genetic Susceptibility;
Keywords: Adipocyte; Breast cancer; Tumor-stroma interaction; CAF; cancer-associated fibroblast; WAT; white adipose tissue; CLS; crown-like structure; CAA; cancer-associated adipocyte; ECM; extracellular matrix; IL; interleukin; ER; estrogen receptor; TNBC; triple-
Keywords: Stem cells; Lysophosphatidic acid; Sphingosine-1-phosphate; ATX; autotaxin; ENPP2; ectonucleotide pyrophosphatase phosphodiesterase 2; EPC; endothelial progenitor cell; ESC; embryonic stem cell; HSPC; hematopoietic stem cell; iPSC; induced pluripotent ste
Keywords: LPA; Autotaxin; Mono-sodium iodoacetate (MIA); Meniscal tear; NSAIDs; Pain;
Keywords: 5-HT(2B); 5-hydroxytryptamine 2B receptor; ACE; angiotensin-converting enzyme; AMPK; AMP-activated protein kinase; ARB; AT1R blocker; ASK1; apoptosis signal-regulating kinase 1; AT1R; angiotensin II type 1 receptor; ATX; autotaxin; BDL; bile duct ligation
Keywords: Lysophosphatidic acid; Autotaxin; Endometrial stromal cell; Primary culture; G protein-coupled receptor;
Keywords: ATX/NPP2; autotaxin; DIPEA; N,N-diisopropylethylamine; DMF; N,N-dimethylformamide; DMSO; dimethylsulfoxide; GPCR; G-protein coupled receptor; GRI; Genomic Research Institute; HBTU; O-(benzotriazol-1-yl)-N,N,Nâ²,Nâ²-tetramethyluronium hexafluorophosphate
Keywords: Phospholipid asymmetry; Lysophosphatidic; Platelet-activating factor; Phosphoinositides; PLRP2; Phospholipase B; 2-AG; 2-arachidonoyl-glycerol; ATX; autotaxin; cPLA2; cytosoluble phospholipase A2; DAG; diacylglycerol; ECs; endocannabinoids; IP3; inositol
Keywords: Acc; acetyl-CoA carboxylase; ASM; acid sphingomyelinase; ATP; adenosine triphosphate; ATPase; adenosine triphosphatase; ATX; autotaxin; BMP; bis(monoacylglycero)phosphate; CDP; cytidine diphosphate; CL; cardiolipin; CNS; central nervous system; COPI; coat
Keywords: Lysophosphatidic acid; Autotaxin; Cholestasis; Pruritus; Neuropathic pain
Keywords: Autotaxin; Osteoarthritis; Plasma; Severity; Synovial fluid;
Keywords: LP; Lysophospholipid; LPA; lysophosphatidic acid; S1P; sphingosine 1-phospate; LPI; lysophosphatidylinositol; LysoPS; lysophosphatidylserine; LPC; lysophosphatidylcholine; LPE; lysophosphatidylethanolamine; LPG; lysophosphatidylglycerol; ATX; autotaxin; S
Keywords: Autotaxin; Bile salts; Cholestasis; Pregnancy; Pruritus;
Keywords: ATX; autotaxin; LPA; lysophosphatidic acid; TDI; toluene diisocyanate; oATP; oxidized ATP; TDA; toluene diamine; MCP-1; monocyte chemoattractant protein-1; Toluene diisocyanate toxicity; Autotaxin-lysophosphatidic acid axis; Purinergic receptors; Microves
Keywords: Autotaxin; Experimental arthritis; ibroblastâlike; fibroblast like; Inflammatory response; Lysophosphatidic acid; Rheumatoid arthritis;
Keywords: Autotaxin; Multiple sclerosis; Lysophosphatidic acid; Cerebrospinal fluid; Enzyme activity; Inflammation;
Keywords: Autotaxin; Glioblastoma multiforme; Lysophosphatidic acid
Keywords: Cholestasis; Itch; Autotaxin; Lysophosphatidate; Pruriception; Bile salts;
Keywords: Autotaxin; Binary QSAR; Docking; Hydrophobic tunnel; Pharmacophore;
Quantitative determination of cyclic phosphatidic acid and its carba analog in mouse organs and plasma using LC-MS/MS
Keywords: 2ccPA; 2-carba-cyclic phosphatidic acid; ATX; autotaxin; BSA; bovine serum albumin; CID; collision-induced dissociation; CNS; central nervous system; cPA; cyclic phosphatidic acid; CV; coefficient of variation; EDTA-Na2; ethylenediaminetetraacetic acid di
Systemic blockade of LPA1/3 lysophosphatidic acid receptors by ki16425 modulates the effects of ethanol on the brain and behavior
Keywords: Alcohol; Self-administration; Conditioned place preference; Two-bottle choice; Withdrawal; Autotaxin;
Metabolomic analysis uncovered an association of serum phospholipid levels with estrogen-induced mammary tumors in female ACI/Seg rats
Keywords: 17β-Estradiol; Lysophosphatidylcholines; Autotaxin; Lysophosphatidic acid receptors; Mammary tumors; Metabolomics;
Discovery and optimization of ATX inhibitors via modeling, synthesis and biological evaluation
Keywords: Autotaxin; Cancer; ATX inhibitors; Molecular docking; Pharmacokinetics;
A rhodium(III)-based inhibitor of autotaxin with antiproliferative activity
Keywords: Rhodium complex; Anticancer; Melanoma; Autotaxin; Inhibitor;
Autotaxin-lysophosphatidic acid receptor signalling regulates hepatitis C virus replication
Keywords: Autotaxin; Lipid signalling; Hepatitis C virus; Hypoxia; Hypoxia-Inducible Factor 1, alpha subunit; Lysophosphatidic acid;
Design, synthesis, docking and biological evaluation of 4-phenyl-thiazole derivatives as autotaxin (ATX) inhibitors
Keywords: Autotaxin; LPC; Cancer; 4-Phenyl-thiazoles; Molecular docking;
Autotaxin, Pruritus and Primary Biliary Cholangitis (PBC)
Keywords: Autotaxin; lysophosphatidylcholine; cholestatic liver diseases; pruritus; autoimmunity
Structural snapshots of the catalytic cycle of the phosphodiesterase Autotaxin
Keywords: Autotaxin; Phosphodiesterase; Alkaline phosphatase; X-ray crystallography; Catalytic mechanism
CNS remyelination as a novel reparative approach to neurodegenerative diseases: The roles of purinergic signaling and the P2Y-like receptor GPR17
Keywords: Purinergic receptors; Oligodendrocytes; Remyelination; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; ATX; autotaxin; CNS; central nervous system; DRG; dorsal root ganglion; EAE; experimental autoimmune encephalomyelitis; GDNF; glial cell de
Lysophospholipid mediators in the vasculature
Keywords: Lysophosphatidic acid; Autotaxin; Lipid phosphate phosphatase; Endothelial cells; Smooth muscle cells; Atherosclerosis;
New insights into the autotaxin/LPA axis in cancer development and metastasis
Keywords: Lysophosphatidic acid; LPA; Autotaxin; ATX; LysoPLD; cancer; metastasis;
Diverse roles of LPA signaling in the intestinal epithelium
Keywords: LPA; lysophosphatidic acid; IEC; intestinal epithelial cell; IBD; inflammatory bowel disease; CRC; colorectal cancer; PA; phosphatidic acid; PLA; phospholipase A; ATX; autotaxin; YAMC; young adult mouse colonic epithelium; MSIE; mouse small intestinal epi
Lysophosphatidic acid mediates fibrosis in injured joints by regulating collagen type I biosynthesis
Keywords: Autotaxin; Lysophosphatidic acid; Chondrocytes; Cartilage injury; Collagen type I; Fibrosis
Opposing regulation of megakaryopoiesis by LPA receptors 2 and 3 in K562 human erythroleukemia cells
Keywords: MEP; megakaryocyte-erythrocyte progenitor; TF; transcription factor; GATA-1; GATA-binding factor 1; EKLF; Kruppel-like factor 1; FLI-1; Friend leukemia integration 1; LPA; lysophosphatidic acid; LPA1; LPA receptor 1; LPA2; LPA receptor 2; LPA3; LPA rece
Autotaxin, a secreted lysophospholipase D, as a promising therapeutic target in chronic inflammation and cancer
Keywords: ABTS; 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid); AML; acute myeloid leukemia; ApnA; diadenosine polyphosphates; ATP; adenosine-5â²-triphosphate; ATX; autotaxin; BALF; bronchoalveolar lavage fluid; bis-pNPP; bis(p-nitrophenyl) phosphate; BLM
Pericytes prevent regression of endothelial cell tubes by accelerating metabolism of lysophosphatidic acid
Keywords: AMD; age-related macular degeneration; ATX; autotaxin; BREC; bovine retinal endothelial cell; BRP; bovine retinal pericyte; EC; endothelial cell; HEK; HEK293 (human embryonic kidney) cell; HUVEC; human umbilical vein endothelial cell; LPA; lysophosphatidi
Autotaxin in the crosshairs: Taking aim at cancer and other inflammatory conditions
Keywords: ATX; autotaxin; BALF; bronchoalveolar lavage fluid; C18:0 etc.; indicates the numbers of carbon atoms in a fatty acid and the number of double bonds; COX-2; cyclooxygenase-2; ENPP2; ecto-nucleotide pyrophosphatase/phosphodiesterase family member 2; EGF; e
Influence of lysophosphatidic acid on estradiol production and follicle stimulating hormone action in bovine granulosa cells
Keywords: Lysophosphatidic acid; Granulosa cells; Cow; Estradiol; Follicle stimulating hormone; LPAR; Autotaxin; Phospholipase A2
Pleiotropic activity of lysophosphatidic acid in bone metastasis
Keywords: Lysophosphatidic acid; Autotaxin; Osteoclast; Osteoblast; Bone metastasis; Mouse model
Autotaxin in embryonic development
Keywords: Autotaxin; Lysophosphatidic acid; Embryonic development; G protein-coupled receptor; Vasculogenesis
Lysophospholipid variants in hepatocellular carcinoma
Keywords: Hepatocellular carcinoma; Transplant; Lysophospholipids; Reprogramming; Autotaxin; Mass spectroscopy
Autotaxin in liver fibrosis
Keywords: Autotaxin; Lysophospholipase D; Liver fibrosis; Lysophosphatidic acid;
Pharmacological evaluation of a novel cyclic phosphatidic acid derivative 3-S-cyclic phosphatidic acid (3-S-cPA)
Keywords: cPA; cyclic phosphatidic acid; LPA; lysophosphatidic acid; ATX; autotaxin; 2ccPA; 2-O-carba-cyclic phosphatidic acid; 3ccPA; 3-O-carba-cyclic phosphatidic acid; Cyclic phosphatidic acid; 3-S-cPA; Autotaxin; Cancer cell migration; Nociceptive reflex; Ische
Biosynthesis of alkyl lysophosphatidic acid by diacylglycerol kinases
Keywords: LPA; lysophosphatidic acid; ATX; autotaxin; 2-AcMAGE; 2-acetyl monoalkylglycerol ether, 1-O-hexadecyl-sn-2-acetyl glycerol; MAGE; monoalkylglycerol ether, 1-O-hexadecyl-sn-glycerol; MAG; monoacylglycerol; AGK/MuLK; acylglycerol kinase/multiple lipid subst
Autotaxin protects microglial cells against oxidative stress
Keywords: Autotaxin; Microglia; Oxidative stress; Free radicals
Autotaxin as a novel serum marker of liver fibrosis
Keywords: Autotaxin; Lysophospholipase D; Hyaluronic acid; Liver stiffness; Liver fibrosis; Lysophosphatidic acid
Hepatocellular Carcinoma Associated Lipid Metabolism Reprogramming
Keywords: hepatocellular carcinoma; phospholipids; autotaxin; lpa; lpc
Synthesis of enantiopure 2-carba-cyclic phosphatidic acid and effects of its chirality on biological functions
Keywords: cPA; Cyclic phosphatidic acid; LPA; Lysophosphatidic acid; ATX; Autotaxin; 2ccPA; 2-carba-cyclic phosphatidic acid; Enantiopure 2-carba-cyclic phosphatidic acid; Stereoselectivity; Chirality; Autotaxin; Cancer cell invasion; Nociceptive reflex;
Serum autotaxin measurements in pregnant women: Application for the differentiation of normal pregnancy and pregnancy-induced hypertension
Keywords: Autotaxin; Pregnancy; Pregnancy-induced hypertension; Lysophosphatidic acid; Lysophospholipase D