Keywords: Receptor guanylyl cyclase; cGMP; CNG channel; Reporter assay;
مقالات ISI (ترجمه نشده)
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Keywords: ADM; adrenomedullin; NO; nitric oxide; MD; major depression; DSM-IV; Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition; NOS; nitric oxide synthase; cGMP; cyclic guanosine monophosphate; CSF; cerebrospinal fluid; CNS; central nervous sy
Keywords: cardiovascular diseases; cell cycle; cell proliferation; diagnostic and therapeutic tools; imaging; nitric oxide; type 2 diabetes; BMC; bone marrow cell(s); cGMP; cyclic guanosine monophosphate; EGFR; epidermal growth factor receptor; eNOS; endothelial
Keywords: I/R; ischemia reperfusion; O2-; superoxide; cGMP; cyclic guanosine monophosphate; NO; nitric oxide; Ach; acetylcholine; Endothelial dysfunction; Endothelium; Statins; Ischemia; Reperfusion;
Keywords: CNP; C-type natriuretic peptide; GC; guanylyl cyclase; NP; natriuretic peptide; WT; wild type; Natriuretic peptides; Guanylate cyclase; Bone growth; cGMP; Dwarfism; Achondroplasia;
Keywords: Phosphodiesterases; LTP; LTD; Depotentiation; Synaptic plasticity; Hippocampus; Cyclic nucleotides; cAMP; cGMP;
Keywords: Benzothiazoles; Rat aorta; Soluble guanylyl cyclase; cGMP; L-type Ca2+ channel;
Keywords: 12; 38; cGMP; cyclic guanosine monophosphate; C-PTIO; 2-(4-carboxypheny)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide; DCD; donation after cardiac death; ELISA; enzyme-linked immunosorbent assay; IL; interleukin; IRI; ischemia-reperfusion injury; LTx;
Keywords: cGMP; cyclic guanosine monophosphate; FACS; fluorescence activated cell sorting; GC; guanylyl cyclases; IL; interleukin; mAbs; monoclonal antibodies; NK cells; nature killer cells; NO; nitric oxide; PDE5; phosphodiesterase 5; TCR; T cell receptor; cGMP; G
Keywords: Cav3; caveolin-3; Cav3+LR; caveolin-3 enriched lipid raft, caveolae; cGMP; cyclic guanosine monophosphate; DEA/NO; diethylammonium (Z)-1-(N,N-diethylamino)diazen-1-ium-1,2-diolate, diethylamine NONOate; ERK5; extracellular signal regulated kinase 5; LR; l
Keywords: Mouse Model; Development; Calcium Signaling; Phosphorylation; ACh; acetylcholine; cGMP; guanosine 3â²,5â²-cyclic monophosphate; CTR; control; ICC; interstitial cells of Cajal; LC17; 17-kilodalton myosin light chain; MHC; myosin heavy chain; MLCK; myosin
Keywords: Fish retina; Optic nerve regeneration; Purpurin; Retinoid signaling; NO signaling; AEC; 3-amino-9-ethylcarbazole; cFXIII; cellular factor XIII; cGMP; cyclic GMP; CNS; central nervous system; CRABPs; cellular retinoic acid-binding proteins; CYP26a1; cytoch
Keywords: ARC; arachidonate-regulated Ca2+ entry channels; BBB; blood-brain barrier; BCEC; bovine brain capillary endothelial cells; BK; bradykinin; CaM; calmodulin; CaMKII; Ca2+/calmodulin-dependent kinase II; cGMP; cyclic guanosine monophosphate; CRAC; Ca2+ rel
Keywords: 8-Br-cGMP; 8-Bromoguanosine 3â²,5â²-cyclic monophosphate; cGMP; guanosine 3â²,5â²-cyclic monophosphate; DAPT; N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-Butyl Ester; EIA; enzyme immunoassay; GSNO; S-Nitrosoglutathione; IOSE; immortalize
Keywords: BDNF; brain derived neurotrophic factor; CAMKII; calmodulin-dependent protein kinase II; Ca2+; calcium; cAMP; cyclic adenosine monophosphate; CBS; cystathionine-β-synthase; CCI; chronic constriction injury; CFA; complete Freund's adjuvant; cGMP; cyclic
Keywords: cAMP; cGMP; Skin; Sheep; Soluble guanylate cyclase (sGC)
Keywords: adverse event; meta-analysis; pharmacovigilance; phosphodiesterase 5 inhibitors; soluble guanylate cyclase stimulators; ADE; adverse drug event; ADR; adverse drug reaction; cGMP; cyclic guanosine monophosphate; GRADE; Grading of Recommendation Assessment,
The role of PKG in oocyte maturation of zebrafish
Keywords: Ovary; Oocyte maturation; Meiosis; PKG; cGMP; Zebrafish;
The dual role of cGMP in oocyte maturation of zebrafish
Keywords: Oocyte maturation; Ovary; Zebrafish; cGMP; Nitric oxide; Luteinizing hormone;
β3-adrenergic receptor activation induces TGFβ1 expression in cardiomyocytes via the PKG/JNK/c-Jun pathway
Keywords: β3-adrenergic receptor; Transforming growth factor β1; Protein kinase G; c-Jun N-Terminal kinase; c-Jun; Cardiomyocyte; AP-1; activator protein 1; β-AR; β-adrenergic receptor; cGMP; cyclic guanosine monophosphate; GRK; G protein-coupled receptor kinas
Pde6brd1 mutation modifies cataractogenesis in Foxe3rct mice
Keywords: Cataract; Foxe3; Genetic modifier; Pde6b; rd1 mutation; Foxe3; forkhead box E3; Pde6b; phosphodiesterase 6B; cGMP; rod receptor, beta polypeptide; RP; retinitis pigmentosa; rd1; retinal degeneration 1; BAC; bacterial artificial chromosome; tg; transgenic;
NO-GC in cells 'off the beaten track'
Keywords: Nitric oxide; cGMP; Guanylyl cyclase; Immunohistochemistry; Pericytes; Cardiomyocytes; Gastrointestinal motility;
Hemodynamic effects of IV sodium nitrite in hospitalized comatose survivors of out of hospital cardiac arrest
Keywords: Sodium nitrite; Out of hospital cardiac arrest; Hypotension; Ischemia reperfusion; S-nitrothiols; cGMP;
The oligomeric assembly of the phosphodiesterase-5 is a mixture of dimers and tetramers: A putative role in the regulation of function
Keywords: PDE5; cGMP; SAXS; Native PAGE-WB; Quaternary assembly; Platelets;
The toxic effects of monosodium glutamate (MSG) - The involvement of nitric oxide, prostanoids and potassium channels in the reactivity of thoracic arteries in MSG-obese rats
Keywords: Monosodium glutamate; Nitric oxide; Obesity; Potassium channels; Thromboxane A2; A23187; calcium ionophore; BKCa; Large Conductance Ca2+-activated K+ channels; cGMP; cyclic guanosine monophosphate; COX; cyclooxygenase; EDCF; endothelial derived contractin
Role of natriuretic peptide receptor 2-mediated signaling in meiotic arrest of zebrafish oocytes and its estrogen regulation through G protein-coupled estrogen receptor (Gper)
Keywords: Zebrafish oocyte maturation; Natriuretic peptide type C, NPPC; Natriuretic peptide receptor 2, NPR2; Meiotic arrest; Phosphodiesterase, PDE; cGMP;
Nitric oxide and cyclic GMP functions in bone
Keywords: Nitric oxide; cGMP; Soluble guanylyl cyclase; Protein kinase G; Bone; Osteoporosis; Osteoblasts; Osteoclasts; Mechanotransduction; Estrogen deficiency;
Expression and localization of phosphodiesterase 2A in the submandibular gland of mice
Keywords: cAMP; cyclic AMP; cGMP; cyclic GMP; PDE2A; phosphodiesterase 2A; NGF; nerve growth factor; PKA; protein kinase A; PKG; protein kinase G; PKG1; protein kinase G1; RT; PCR, reverse transcription-polymerase chain reaction; Serpinb6a; serine (or cysteine) pep
Long-term inhibition of PDE5 ameliorates aging-induced changes in rat testis
Keywords: Actb/ACTB; gene/protein for β-actin; AKT; protein for protein kinase B (AKT/PRKGB); BSA; bovine serum albumin; cAMP; cyclic adenosine monophosphate; cGMP; cyclic guanosine monophosphate; Cyp11a1; gene for cytochrome P450 side chain cleavage enzyme; Cyp17
HFpEF, a Disease of the Vasculature: A Closer Look at the Other Half
Keywords: cAMP; cyclic adenosine 3â²,5â²-monophosphate; cGMP; cyclic guanosine monophosphate; EF; ejection fraction; HFpEF; heart failure with preserved ejection fraction; HFrEF; heart failure with reduced ejection fraction; KO; knockout; LV; left ventricular; LZ
Identification of a soluble guanylate cyclase in RBCs: preserved activity in patients with coronary artery disease
Keywords: cGMP; Nitric oxide; Protein kinase G; Signaling; Non -canonical functions of RBCs;
Involvement of the NO/sGC/cGMP/K+ channels pathway in vascular relaxation evoked by two non-quinazoline α1-adrenoceptor antagonists
Keywords: 4-AP; 4-amynopiridine; AC; adenylyl cyclase; BPH; benign prostatic hyperplasia; COX; cyclooxygenase; DAG; diacylglycerol; EDHF; endothelium-derived hyperpolarizing factor; eNOS; endothelial NO synthase; GLI; glibenclamide; HAEC; human aortic endothelial c
(2R,3S)-Pinobanksin-3-cinnamate promotes osteoblast differentiation through cAMP and cGMP pathways
Keywords: (2R ;3S)-pinobanksin-3-cinnamate; Osteoblast differentiation; MC3T3-E1 cells; cAMP; cGMP;
Apelin, a promising target for Alzheimer disease prevention and treatment
Keywords: Alzheimer disease; Apelin; Amyloid beta; Central nervous system; Oxidative stress; AAA; Abdominal aortic aneurysm; ABCA1; ATP-binding cassette transporter A1; ACE; Angiotensin converting enzyme; ACh; Acetylcholine; AChE; Acetyl choline esterase; AD; Alzhe
Crystal structure and substrate specificity of ExoY, a unique T3SS mediated secreted nucleotidyl cyclase toxin from Pseudomonas aeruginosa
Keywords: X-ray crystallography; Nucleotidyl cyclase toxins; T3SS; Anthrax toxA family; Non-canonical secondary messengers; One-metal-ion dependent catalysis; ExoY; exogenous toxin Y; T3SS; Type III secretory systems; AA-NC; actin-activated nucleotidyl cyclase; EF;
Formaldehyde regulates vascular tensions through nitric oxide-cGMP signaling pathway and ion channels
Keywords: Formaldehyde; Thoracic aorta ring; Vascular tension; Ion channels; Signal pathway; 4-AP; 4-aminopyridine; ACh; acetylcholine; l-NAME; NG-nitro-l-arginine methyl ester; ACE; angiotensin-converting enzyme; VSMCs; vascular smooth muscle cells; BKCa; big-cond
The dichotomous role of H2S in cancer cell biology? Déjà vu all over again
Keywords: 1400 W; N-[[3-(aminomethyl)phenyl]methyl]-ethanimidamide; 3-MP; 3-Mercaptopyruvate; 3-MST; 3-Mercaptopyruvate sulfurtransferase; ADT-OH; 5-(4-hydroxyphenyl)-3H-1, 2-dithiole-3-thione; AG; Aminoguanidine; AOAA; Aminooxyacetic acid; CAT; Cysteine aminotra
A conjugate of decyltriphenylphosphonium with plastoquinone can carry cyclic adenosine monophosphate, but not cyclic guanosine monophosphate, across artificial and natural membranes
Keywords: cAMP; adenosine 3â²,5â²-cyclic monophosphate; cGMP; guanosine 3â²,5â²-cyclic monophosphate; 8-Br-cAMP; 8-bromoadenosine 3â²,5â²-cyclic monophosphate; 8-Br-cGMP; 8-bromoguanosine 3â²,5â²-cyclic monophosphate; PKA; protein kinase A; PKG; protein kin
D-pinitol attenuates cisplatin-induced nephrotoxicity in rats: Impact on pro-inflammatory cytokines
Keywords: Nephrotoxicity; D-pinitol; Cisplatin; Sutherlandia fruitcence; ATP; adenosine triphosphate; cGMP; cyclic guanosine monophosphate; DNA; deoxyribonucleic acid; eNOS; endothelial nitric oxide synthase; ERK; extracellular-signal-regulated kinases; H2O2; Hydro
Novel H2S-NO hybrid molecule (ZYZ-803) promoted synergistic effects against heart failure
Keywords: CBS; Cystathionine β-synthase; cGMP; Guanosine 5â²-monophosphate; CSE; Cystathionine γ-lyase; EF; Ejection fraction; eNOS; Endothelial NO synthase; FS; Fractional shortening; GPx; Glutathione peroxidase; HO-1; Heme oxygenase 1; H2S; Hydrogen sulfide; L
The role of hydrogen sulfide in cyclic nucleotide signaling
Keywords: Hydrogen sulfide; Cyclic nucleotide; cAMP; cGMP; Phosphodiesterase; Hypertension; Cardioprotection;
Effect of ginger, Paullinia cupana, muira puama and l- citrulline, singly or in combination, on modulation of the inducible nitric oxide- NO-cGMP pathway in rat penile smooth muscle cells
Keywords: iNOS; cGMP; PDE 5 cavernosal smooth muscle cells;
Cardiac natriuretic peptides promote adipose 'browning' through mTOR complex-1
Keywords: Thermogenesis; UCP1; Kinases; βAR; β-adrenergic receptor; 8-Br-cAMP; 8-Bromoadenosine 3â²,5â²-cyclic monophosphate; 8-Br-cGMP; 8-Bromoguanosine 3â²,5â²-cyclic monophosphate; Akt; protein kinase B; ANP; Atrial natriuretic peptide; BNP; B-type natriur
Screening of the ability of natural feed ingredients commonly used in pig diets to interfere with the attachment of ETEC K88 (F4) to intestinal epithelial cells
Keywords: ETEC; Enterotoxigenic Escherichia coli; AT; adhesion test; IPEC-J2; intestinal epithelial cells; BT; blocking test; CGMP; casein glycomacropeptide; NF; non-fimbriated; LB; Luria broth; OD; optical density; DMEM; Dulbecco´s Modified Eagle Medium; CFU; col
S-Nitroso-N-acetyl-L-cysteine ethyl ester (SNACET) and N-acetyl-L-cysteine ethyl ester (NACET)-Cysteine-based drug candidates with unique pharmacological profiles for oral use as NO, H2S and GSH suppliers and as antioxidants: Results and overview
Keywords: CGMP; Nitric oxide; S-Nitrosothiols; Oxidative stress; Pharmaceuticals;
3,7-Bis(2-hydroxyethyl)icaritin, a potent inhibitor of phosphodiesterase-5, prevents monocrotaline-induced pulmonary arterial hypertension via NO/cGMP activation in rats
Keywords: 3,7-Bis(2-hydroxyethyl)icaritin; Pulmonary arterial hypertension; PDE5 inhibitor; NO; cGMP;
cGMP is involved in Zn tolerance through the modulation of auxin redistribution in root tips
Keywords: Auxin; cGMP; PIN4; Root development; Arabidopsis thaliana;
Investigation of the therapy targets of Yi-Qi-Yang-Yin-Hua-Tan-Qu-Yu recipe on type 2 diabetes by serum proteome labeled with iTRAQ
Keywords: T2DM; type 2 diabetes mellitus; IR; insulin resistance; HFD; high-fat diet; cAMP; cyclic adenosine monophosphate; cGMP; cyclic guanosine monophosphate; TG; triglyceride; TC; total cholesterol; TXB2; thromboxane B2; 6-keto PGF1α; 6-keto prostaglandin F1α
Astaxanthin: A mechanistic review on its biological activities and health benefits
Keywords: Astaxanthin (PubChem CID: 5368397); Beta-Carotene (PubChem CID: 5280489); Beta-Cryptoxanthin (PubChem CID: 5281235); Canthaxanthin (PubChem CID: 5281227); Lutein (PubChem CID: 5281243); Zeaxanthin (PubChem CID: 5280899); Alpha-Tocopherol (PubChem CID: 149
Betulinic acid, a natural PDE inhibitor restores hippocampal cAMP/cGMP and BDNF, improve cerebral blood flow and recover memory deficits in permanent BCCAO induced vascular dementia in rats
Keywords: Betulinic acid; Neuroinflammation; vascular dementia; cAMP; cGMP; Microgliosis;