Keywords: بی ثباتی کروموزومی; Colorectal cancer; Cytokines; Immune response; Immunotherapy; Inflammation; Anatomical subsite heterogeneity; CIMP; CpG island methylator phenotype; CIN; chromosomal instability; CRC; colorectal cancer; FGF-2; fibroblast growth factor 2 (basic); G-CSF; gr
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Keywords: بی ثباتی کروموزومی; APC/C; anaphase-promoting complex/cyclosome; BNC; binucleated cell; CB; chromatin bridge; CBMN; cytokinesis-block micronucleus assay; CIN; chromosomal instability; CL; chromosome lagging; CMA; chromosome misalignment; MN; micronucleus; MPA; multipolar ali
Keywords: بی ثباتی کروموزومی; APC; Antigen presenting cells; CIMP; CpG island methylator phenotype; CIN; chromosomal instability; CRC; colorectal cancer; CTLA-4; cytotoxic T lymphocyte-associated protein 4; DAMPs; danger-associated molecular patterns; FDA; US Food and Drug Administr
Keywords: بی ثباتی کروموزومی; Chromosomal instability; Micronucleus; Nuclear buds; Aneuploidy; Scoring;
Keywords: بی ثباتی کروموزومی; Gastric Cancer; Genomics; Next-Generation Sequencing; Driver Gene Mutations; ACRG; Asian Cancer Research Group; CIN; chromosomal instability; EBV; Epstein-Barr virus; EMT; epithelial-to-mesenchymal transition; GS; genomic stability; MSI; microsatellite
Keywords: بی ثباتی کروموزومی; aCGH; array comparative genomic hybridization; CIMP; CpG island methylator phenotype; CIN; chromosomal instability; CNA; copy number alteration; CRC; colorectal cancer; DFS; disease-free survival; EOCRC; early-onset colorectal cancer; GII; genomic Instabi
Keywords: بی ثباتی کروموزومی; Hepatocellular carcinoma; Personalized medicine; Sorafenib; Biomarkers; Molecular marker based-therapy; Individualized therapy; HCC; hepatocellular carcinoma; ICC; intrahepatic cholangiocarcinoma; PCNA; proliferating cell nuclear antigen; CIN; chromosomal
Keywords: بی ثباتی کروموزومی; Endometrial carcinoma; Genetics; Microsatellite instability; PTEN; PIK3CA; K-RAS; Beta-catenin; Apoptosis; Chromosomal instability; E-cadherin; TP53;
Keywords: بی ثباتی کروموزومی; Coal mining; Chromosomal instability; DNA damage; Drosophila melanogaster; V79; HepG2;
Keywords: بی ثباتی کروموزومی; ATM; ataxia-telangiectasia mutated; BCL2L1; BCL2 like 1; CGH; comparative genomic hybridization; CHK; checkpoint kinase 1; CIN; chromosomal instability; CNVs; copy number variations; DNMT3B; DNA methyltransferase 3B; DPPA3; developmental pluripotency asso
Keywords: بی ثباتی کروموزومی; CRC; colorectal cancer; SNP; single nucleotide polymorphism; CNV; copy number variant; GWAS; genome-wide association studies; GO; gene ontology; BP; biological process; CAM; cell adhesion molecule; CIN; chromosomal instability; MSI; microsatellite instabi
Keywords: بی ثباتی کروموزومی; Chromosomal instability; Aneuploidy; Cancer; Chromosome segregation; Kinetochore; Mitosis
Keywords: بی ثباتی کروموزومی; CFE; colony forming efficiency; CIN; chromosomal instability; CSC; cancer stem cell; ELDA; extreme limiting dilution assessment; FISH; fluorescence in situ hybridization; HNSCC; head and neck squamous cell carcinoma; IR; ionizing radiation; NSCLC; non-sma
Keywords: بی ثباتی کروموزومی; Predictive Markers; Prognostic Markers; Colorectal Cancer; Molecular Subtypes; RAS; BRAF; MSI; DNA Mismatch Repair; Immunotherapy; Targeted Therapy; Biologics; Anti-EGFR; Anti-VEGF; CCS; colon cancer subtypes; CIMP; CpG island methylator phenotype; CIN; c
Keywords: بی ثباتی کروموزومی; Chromosomal instability; Microsatellite instability; Driver mutation; Passenger mutation;
Keywords: بی ثباتی کروموزومی; centrosome disjunction; centrosome movement; centrosome dynamics; chromosomal instability; cancer
Keywords: بی ثباتی کروموزومی; Ionising radiation; Chemical exposures; Telomeres; DNA repair; Cellular stress; Chromosomal instability;
Keywords: بی ثباتی کروموزومی; Intratumoral heterogeneity; Centrosomes; Chromosomal instability; Mitotic propensity; Biomarker
Keywords: بی ثباتی کروموزومی; Cancer Genetics; Cancer Genomics; Gastric Cancer; CIMP; CpG island methylation phenotype; CIN; Chromosomal instability; EBV; Epstein-Barr virus; EMT; epithelial-mesenchymal transition; GC; gastric cancer; GS; genome stable; Helicobacter pylori; H pylori;
Keywords: بی ثباتی کروموزومی; Colorectal cancer; Chromosomal instability; Microsatellite instability; Serrated neoplasia pathway; Colonoscopy; Colorectal polyps;
Keywords: بی ثباتی کروموزومی; Vaginal cancer; Clear cell adenocarcinoma; PIK3CA mutation; Chromosomal instability; Concurrent chemoradiation therapy
Keywords: بی ثباتی کروموزومی; Telomere; PUNLMP; Urothelial carcinoma; Q-FISH; Chromosomal instability; Anaphase bridge; Karyotype analysis
Keywords: بی ثباتی کروموزومی; Telomeres; Ionizing radiation; Bystander effect; Radiosensitivity; Chromosomal instability;
DNA replication stress drives fragile site instability
Keywords: بی ثباتی کروموزومی; Replication stress; Common fragile sites; Chromosomal instability;
Silencing of PRR11 suppresses cell proliferation and induces autophagy in NSCLC cells
Keywords: بی ثباتی کروموزومی; Akt/mTOR; Autophagy; Cell proliferation; Non-small-cell lung cancer; PRR11; proline-rich protein 11; (PRR11); small cell lung cancer; (SCLC); non-small-cell lung cancer; (NSCLC); Cell Counting Kit-8; (CCK8); lysosome-associated membrane protein 1; (Lamp1)
Mutational game changer: Chromothripsis and its emerging relevance to cancer
Keywords: بی ثباتی کروموزومی; SAC; spindle assembly checkpoint; APOBEC; apolipoprotein B mRNA-editing catalytic subunit; SNP; single-nucleotide polymorphism; array-CGH; comparative genomic hybridization; CLTP; chromothripsis-like pattern; SKY; spectral karyotyping; FISH; fluorescent i
Correlation of MYC Gene and Protein Status With Breast Cancer Subtypes and Outcome of Patients Treated With Anthracycline-Based Adjuvant Chemotherapy. Pooled Analysis of 2 Hellenic Cooperative Group Phase III Trials
Keywords: بی ثباتی کروموزومی; Chromosomal instability; MYC gene amplification; MYC immunohistochemistry; Paclitaxel; Polysomy 8;
Overexpression of Rac GTPase Activating Protein 1 Contributes to Proliferation of Cancer Cells by Reducing Hippo Signaling to Promote Cytokinesis
Keywords: بی ثباتی کروموزومی; Binucleated Cells; Large Tumor Suppressor Kinase; Pan-overexpressed; TEA Domain Transcription Factor; AURKB; aurora B kinase; ChIP; chromatin immunoprecipitation; CIN; chromosomal instability; CNL; noncancerous tissue; ECT2; epithelial cell transforming 2
Case report: Chondrosarcoma of the head and neck
Keywords: بی ثباتی کروموزومی; Chondrosarcoma; Head and neck; Maxilectomia; Molecular study; Chromosomal instability; Tumor undifferentiation; Pathology; Cytology;
Chromosome instability in tumor resection margins of primary OSCC is a predictor of local recurrence
Keywords: بی ثباتی کروموزومی; OSCC; oral cavity squamous cell carcinoma; FISH; fluorescence in situ hybridization; CI; chromosomal instable neoplasia; CIS; carcinoma in situ; LOH; loss of heterozygosity; MPTC; Maastricht Pathology Tissue Collection Department; CNV; copy number variati
ReviewTransient and stable vector transfection: Pitfalls, off-target effects, artifacts
Keywords: بی ثباتی کروموزومی; CIN; chromosomal instability; GFP; green fluorescent protein; Pac; the puromycin N-acetyltransferase; Sh ble; Streptoalloteichus hindustanus bleomycin resistance gene; Neo; aminoglycoside 3â²-phosphotransferase gene; Aneuploidy; Chromosomal instability;
Oxidative stress induces mitotic arrest by inhibiting Aurora A-involved mitotic spindle formation
Keywords: بی ثباتی کروموزومی; CIN; chromosomal instability; CKIs; CDK inhibitors; DDC; sodium diethyldithiocarbamate trihydrate; GSK-3; glycogen synthase kinase 3; NAC; N-acetyl-L-cysteine; PCM; pericentriolar material; PCNT; pericentrin; ROS; reactive oxygen species; SAC; spindle ass
Sporadic Early-Onset Diffuse Gastric Cancers Have High Frequency of Somatic CDH1 Alterations, but Low Frequency of Somatic RHOA Mutations Compared With Late-Onset Cancers
Keywords: بی ثباتی کروموزومی; Young; Stomach; Age; Genomic; CIN; chromosomal instability; DGC; diffuse gastric cancer; EBV; Epstein-Barr virus; EO; early onset; GC; gastric cancer; GS; genomically stable; HR; hazard ratio; LO; late onset; MSI; microsatellite instability; SNV; single n
Establishing a murine xenograft-model for long-term analysis of factors inducing chromosomal instability in myelodysplastic syndrome: Pitfalls and successes
Keywords: بی ثباتی کروموزومی; Mouse model; leukemia; MDS; chromosomal instability; transplantation
Distinct set of chromosomal aberrations in childhood hepatocellular carcinoma is correlated to hepatitis B virus infection
Keywords: بی ثباتی کروموزومی; HCC; HBV; chromosomal instability; children; adjacent non-neoplastic tissues; aCGH;
Personalised pathway analysis reveals association between DNA repair pathway dysregulation and chromosomal instability in sporadic breast cancer
Keywords: بی ثباتی کروموزومی; DNA repair; Homologous recombination; Breast cancer; Chromosomal instability; Pathway analysis;
Mutated MCM9 is associated with predisposition to hereditary mixed polyposis and colorectal cancer in addition to primary ovarian failure
Keywords: بی ثباتی کروموزومی; DNA helicase MCM9; primary ovarian failure; hereditary mixed polyposis; chromosomal instability; colorectal cancer
KRAS and aneusomy of chromosomes 4, 10 and 12 in colorectal carcinomas
Keywords: بی ثباتی کروموزومی; Colon cancer; RAS; Ploidy; Aneusomy; Chromosomal instability
Topoisomerase-1 and -2A gene copy numbers are elevated in mismatch repair-proficient colorectal cancers
Keywords: بی ثباتی کروموزومی; FISH; Topoisomerase 1; Topoisomerase 2A; MMR; Chromosomal instability; Gene copy number; TOP1; gene symbol for the gene encoding topoisomerase 1; TOP2A; gene symbol for the gene encoding topoisomerase 2 alpha; CEN17; symbol for the chromosomal region enco
Original ResearchFull Report: Clinical-Alimentary TractMolecular Markers Identify Subtypes of Stage III Colon Cancer Associated With Patient Outcomes
Keywords: بی ثباتی کروموزومی; Colorectal Cancer; Oncogene; Prognostic Factor; Genetics; CI; confidence interval; CIMP; CpG island methylator phenotype; CIN; chromosomal instability; CRC; colorectal cancer; DFS; disease-free survival; dMMR; deficient DNA mismatch repair; FOLFOX; 5-fluo
Genetics and Genetic Biomarkers in Sporadic Colorectal Cancer
Keywords: بی ثباتی کروموزومی; Genomic Instability; Microsatellite Instability; Chromosomal Instability; CIMP; ACF; aberrant crypt focus; CIMP; CpG island methylator phenotype; CIN; chromosomal instability; Cox-2; cyclo-oxygenase-2; CRC; colorectal cancer; EGFR; epithelial growth facto
Induction of genetic instability by transfer of a UV-A-irradiated chromosome
Keywords: بی ثباتی کروموزومی; Chromosomal instability; UV-A; Chromosomal aberration; DNA damage; Microcell-mediated chromosome transfer; Polyploidy;
Genetic evaluation of mesenchymal stem cells by G-banded karyotyping in a Cell Technology Center
Keywords: بی ثباتی کروموزومی; Cytogenetics; Mesenchymal stromal cells; Chromosomal instability
Role of topoisomerase I and thymidylate synthase expression in sporadic colorectal cancer: Associations with clinicopathological and molecular features
Keywords: بی ثباتی کروموزومی; Topoisomerase I; Thymidylate synthase; Colorectal cancer; Chromosomal instability; 18qLOH
Deletion of BRCA2 exon 27 causes defects in response to both stalled and collapsed replication forks
Keywords: بی ثباتی کروموزومی; BRCA2; RAD51; Replication fork stalling; Double strand break; Chromosomal instability
Chromosome instability and carcinogenesis: Insights from murine models of human pancreatic cancer associated with BRCA2 inactivation
Keywords: بی ثباتی کروموزومی; Pancreatic cancer; BRCA2; Genetically engineered mouse model; Chromosomal instability; Hereditary cancer predisposition;
Voies de carcinogenèse et histoire naturelle des tumeurs de la voie excrétrice supérieure : état de l’art pour le rapport annuel de l’Association française d’urologie
Keywords: بی ثباتی کروموزومی; Carcinome urothélial; Clonalité; Carcinogenèse; Mutations; Instabilité chromosomique; Syndrome de Lynch; Polymorphisme génétiqueUrothelial carcinoma; Renal pelvis; Ureter; Clonal evolution; Carcinogenesis; Mutation; Chromosomal instability; Genetic polymo
Loss of DAXX and ATRX Are Associated With Chromosome Instability and Reduced Survival of Patients With Pancreatic Neuroendocrine Tumors
Keywords: بی ثباتی کروموزومی; Pancreas; Neoplasm ALT; Prognosis; Human; ALT; alternative lengthening telomeres; ATRX; ATR-X gene; CGH; comparative genomic hybridization; CI; confidence interval; CIN; chromosomal instability; DAXX; death domain-associated protein gene; Exp(B); odds r
Artichoke induces genetic toxicity in the cytokinesis-block micronucleus (CBMN) cytome assay
Keywords: بی ثباتی کروموزومی; Cynara scolymus L.; CBMN; Chromosomal instability; MNi; Mammalian cells;
A single mutation in Securin induces chromosomal instability and enhances cell invasion
Keywords: بی ثباتی کروموزومی; Securin; pttg; Cell invasiveness; Tumourigenesis; Chromosomal instability; Pituitary tumour; Human mutation;