Keywords: Indole-3-carbinol (PubChem CID: 3712); Diindolylmethane (PubChem CID: 3071); 4-(Methylnitro-samino)-1-(3-pyridyl)-1-butanone (PubChem CID: 47,289); Liposomes; Indole-3-carbinol; 4-(Methylnitro-samino)-1-(3-pyridyl)-1-butanone; Cytochrome P450 1A1; DNA add
مقالات ISI (ترجمه نشده)
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Keywords: multi-omics; epigenetics; DNA adduct; phosphorothioation; methylation
Keywords: Ï-6 polyunsaturated fatty acids; Isotope dilution liquid chromatography-electrospray ionization-tandem mass spectrometry; DNA adduct; Antioxidants; Free radicals;
Synergistic effects of H3 and H4 nucleosome tails on structure and dynamics of a lesion-containing DNA: Binding of a displaced lesion partner base to the H3 tail for GG-NER recognition
Keywords: B[a]P; benzo[a]pyrene; PTM; posttranslational modification; NER; nucleotide excision repair; NCP; nucleosome core particle; PDB; protein data bank; MD; molecular dynamics; cis-B[a]P-dG; 10R (+)-cis-anti-B[a]P-N2-dG adduct; SHL; super-helical location; RMS
Broad spectrum detection of DNA damage by Repair Assisted Damage Detection (RADD)
Keywords: RADD; repair assisted DNA damage detection; TUNEL; Terminal deoxynucleotidyl transferase nick end labeling; ISEL; In situ end label; DDR; DNA damage response; TdT; terminal deoxynucleotidyl transferase; dUTP; deoxyuracil triphosphate; CSK; cytoskeletal bu
Mass spectrometry investigation of DNA adduct formation from bisphenol A quinone metabolite and MCF-7 cell DNA
Keywords: 3-OH-BPA-N7dA; 3-hydroxy-bisphenol A-deoxyadenosine; 3-OH-BPA-N7Ade; 3-hydroxy-bisphenol A-adenine; 3-OH-BPA-N7dG; 3-hydroxy-bisphenol A-N7-deoxyguanosine; 3-OH-BPA-N7Gua; 3-hydroxy-bisphenol A-N7-guanine; BPA; bisphenol A; BPAP; bisphenol AP; BPAQ; bisph
From in vitro to in vivo: Integration of the virtual cell based assay with physiologically based kinetic modelling
Keywords: VCBA; PBK; PBD; Estragole; DNA adduct; Risk assessment; KNIME workflow;
Short communicationIn vitro study of the effect of metabolism enzymes on benzo(a)pyrene-induced DNA damage in the scallop Chlamys farreri
Keywords: Chlamys farreri; Benzo(a)pyrene; In vivo; Metabolic enzymes; DNA adduct; 8-Hydroxy-2-deoxyguanosine;
TP53 and lacZ mutagenesis induced by 3-nitrobenzanthrone in Xpa-deficient human TP53 knock-in mouse embryo fibroblasts
Keywords: TP53; Mutation; Nucleotide excision repair; 3-Nitrobenzanthrone; DNA adduct; Environmental carcinogen;
Effect of conformation of the arylamine-DNA adduct on the sensitivity of [Ru(phen)2(dppz)]2Â + complex
Keywords: Arylamine; DNA adduct; Ru(II) complex; Acetylaminofluorene; Aminofluorene;
Chromium (VI) potentiates the DNA adducts (O6-methylguanine) formation of N-nitrosodimethylamine in rat: Implication on carcinogenic risk
Keywords: Cr(VI); Nitrosamines; DNA adduct; CYP 2E1 enzyme activity; GSH
Estrogen-like metabolites and DNA-adducts in urogenital schistosomiasis-associated bladder cancer
Keywords: Squamous cell carcinoma; Schistosomiasis; Bladder; Angola; Catechol estrogen quinone; DNA adduct
Adduct levels from benzo[a]pyrenediol epoxide: Relative formation to histidine in serum albumin and to deoxyguanosine in DNA in vitro and in vivo in mice measured by LC/MS-MS methods
Keywords: DNA adduct; Serum albumin; Histidine adduct; Benzo[a]pyrene diolepoxide; HPLC/MS-MS;
Effects of deletion of the transcription factor Nrf2 and benzo [a]pyrene treatment on ovarian follicles and ovarian surface epithelial cells in mice
Keywords: NRF2; Ovarian aging; Benzo[a]pyrene; Oxidative stress; Polycyclic aromatic hydrocarbon; DNA adduct;
Curcumin inhibits PhIP induced cytotoxicity in breast epithelial cells through multiple molecular targets
Keywords: Phytochemicals; Cancer prevention; Reactive oxygen species; DNA damage; DNA adduct; Heterocyclic amines; AOPI; acridine orange/propidium iodide; BRCA-1; breast cancer 1 early onset; CAT; catalase; DCFDA; 2â²,7â²-dichlorodihydrofluorescein diacetate; DEP
Interaction of benzo[a]pyrene with other risk factors in hepatocellular carcinoma: a case-control study in Xiamen, China
Keywords: Hepatocellular carcinoma; Benzo[a]pyrene; DNA adduct; Case-control study; Risk factor
Noninvasive measurement of smoking-associated N3-ethyladenine and N7-ethylguanine in human salivary DNA by stable isotope dilution nanoflow liquid chromatography-nanospray ionization tandem mass spectrometry
Keywords: DNA adduct; 3-Ethyladenine; 7-Ethylguanine; Nanoflow LC-MS/MS; Saliva;
Detection and simultaneous quantification of three smoking-related ethylthymidine adducts in human salivary DNA by liquid chromatography tandem mass spectrometry
Keywords: DNA adduct; Ethylthymidine; Nanoflow LC; Mass spectrometry; Saliva
Effect of long-term human exposure to environmental heavy metals on the expression of detoxification and DNA repair genes
Keywords: Cadmium; DNA adduct; Mercury; Mining activity; Lead;
Adduct formation and repair, and translesion DNA synthesis across the adducts in human cells exposed to 3-nitrobenzanthrone
Keywords: 3-NBA; 3-nitrobenzanthrone; ABA; aminobenzanthrone; dA-N6-C2-ABA; 2-(2â²-deoxyadenosin-N6-yl)-3-aminobenzanthrone; dG-C8-N-ABA; N-(2â²-deoxyguanosin-8-yl)-3-aminobenzanthrone; dG-N2-C2-ABA; 2-(2â²-deoxyguanosin-N2-yl)-3-aminobenzanthrone; MRM; multiple
Simultaneous quantification of ethylpurine adducts in human urine by stable isotope dilution nanoflow liquid chromatography nanospray ionization tandem mass spectrometry
Keywords: DNA adduct; 3-Ethyladenine; 7-Ethylguanine; Nanoflow LC; Mass spectrometry; Urine
Oligonucleotide probes containing pyrimidine analogs reveal diminished hydrogen bonding capacity of the DNA adduct O6-methyl-G in DNA duplexes
Keywords: DNA adduct; Oligonucleotide binding; Nucleoside analog
Topographical study of O6-alkylguanine DNA alkyltransferase repair activity and N7-methylguanine levels in resected lung tissue
Keywords: Smoking; DNA adduct; Lung cancer; DNA repair; O6-Alkylguanine DNA-alkyltransferase; N7-methylguanine
Simultaneous quantitative analysis of N3-ethyladenine and N7-ethylguanine in human leukocyte deoxyribonucleic acid by stable isotope dilution capillary liquid chromatography–nanospray ionization tandem mass spectrometry
Keywords: DNA adduct; Ethyladenine; Ethylguanine; Capillary LC–NSI/MS/MS; Leukocyte; Smoking
Response of Lumbriculus variegatus transcriptome and metabolites to model chemical contaminants
Keywords: Actin; Antioxidant; DNA adduct; Intracellular metabolite; Lumbriculus variegatus; Microarray; Proteases
Dioxin suppresses benzo[a]pyrene-induced mutations and DNA adduct formation through cytochrome P450 1A1 induction and (±)-anti-benzo[a]pyrene-7,8-diol-9,10-epoxide inactivation in human hepatoma cells
Keywords: Benzo[a]pyrene; BPDE; DNA adduct; TCDD; Cytochrome P450 1A1
Stability of acetaldehyde-derived DNA adduct in vitro
Keywords: AA; acetaldehyde; ALDH2; aldehyde dehydrogenase-2; LC/MS/MS; liquid chromatography-tandem mass spectrometry; N2-ethylidene-dG; N2-ethylidene-2â²-deoxyguanosine; N2-Et-dG; N2-ethyl-2â²-deoxyguanosine; α-Me-γ-OH-PdG; α-methyl-γ-hydroxy-1, N2-propano
Possible involvement of sulfotransferase 1A1 in estragole-induced DNA modification and carcinogenesis in the livers of female mice
Keywords: Estragole; gpt delta mice; DNA adduct; Micronucleus test;
Formation and characterization of covalent guanosine adducts with electrochemistry-liquid chromatography-mass spectrometry
Keywords: Electrochemistry; Mass spectrometry; Nucleic acids; Liquid chromatography; DNA adduct; DNA damage;
Reduced 4-aminobiphenyl-induced liver tumorigenicity but not DNA damage in arylamine N-acetyltransferase null mice
Keywords: Aromatic amine; Chemical carcinogen; Arylamine N-acetyltransferase; DNA adduct; Liver cancer; Sex differences
An approach based on ultra-high pressure liquid chromatography–tandem mass spectrometry to quantify O6-methyl and O6-carboxymethylguanine DNA adducts in intestinal cell lines
Keywords: DNA adduct; N-nitroso compound; UHPLC–MS/MS; Red meat; Colonocytes
Processing of anthracycline-DNA adducts via DNA replication and interstrand crosslink repair pathways
Keywords: Anthracycline; DNA adduct; DNA repair; Homologous recombination; Interstrand crosslink
Application of the DNA adductome approach to assess the DNA-damaging capability of in vitro micronucleus test-positive compounds
Keywords: Adductome; DNA adduct; In vitro micronucleus test; LC/MS/MS
A novel and specific method for the determination of aristolochic acid-derived DNA adducts in exfoliated urothelial cells by using ultra performance liquid chromatography-triple quadrupole mass spectrometry
Keywords: Aristolochic acid; DNA adduct; Ultra performance liquid chromatography-tandem mass spectrometry; Multiple reaction monitoring;
Tumor prevalence and biomarkers of genotoxicity in brown bullhead (Ameiurus nebulosus) in Chesapeake Bay tributaries
Keywords: Biomarker; Brown bullhead; DNA adduct; PAH; Tumor; Alkylating agent
Towards biomarker-dependent individualized chemotherapy: Exploring cell-specific differences in oxaliplatin–DNA adduct distribution using accelerator mass spectrometry
Keywords: Oxaliplatin; DNA adduct; Accelerator mass spectrometry
Exposure to polycyclic aromatic hydrocarbons and missed abortion in early pregnancy in a Chinese population
Keywords: Polycyclic aromatic hydrocarbon; DNA adduct; Air pollution; Pregnancy outcome; Abortion
Benzene-derived N2-(4-hydroxyphenyl)-deoxyguanosine adduct: UvrABC incision and its conformation in DNA
Keywords: HQ; hydroquinone; p-BQ; p-benzoquinone; N2-4-HOPh-dG; N2-(4-hydroxyphenyl)-2'-deoxyguanosine; AP; apurinic/apyrimidinic; UvrABC; E. coli UvrABC complex; NER; nucleotide excision repair; BER; base excision repair; Exo III; exonuclease III; Endo IV; endon
An improved liquid chromatography–tandem mass spectrometry method for the quantification of 4-aminobiphenyl DNA adducts in urinary bladder cells and tissues
Keywords: DNA adduct; 4-Aminobiphenyl (4-ABP); N-(Deoxyguanosin-8-yl)-4-aminobiphenyl (dG-C8-4-ABP); HPLC–MS/MS; Urinary bladder cancer; Aromatic amine
Combinatorial effect of fish oil (Maxepa) and 1α,25-dihydroxyvitamin D3 in the chemoprevention of DMBA-induced mammary carcinogenesis in rats
Keywords: Mammary tumorigenesis; Rodent; Fish oil; Vitamin D3; DNA adduct; Cell proliferation
Quantitative methods for studying DNA interactions with chemotherapeutic cisplatin
Keywords: Antibody; Cancer; Cisplatin; DNA adduct; Immunochemical assay; Inductively coupled plasma; ICP-MS; Mass spectrometry; Post-labeling, Quantification; Sample processing
The genotoxic air pollutant 3-nitrobenzanthrone and its reactive metabolite N-hydroxy-3-aminobenzanthrone lack initiating and complete carcinogenic activity in NMRI mouse skin
Keywords: 3-Nitrobenzanthrone; 7,12-Dimethylbenz[a]anthracene; Carcinogenesis; DNA adduct; Diesel exhaust; Air pollution
Mutagenicity of DNA adducts derived from ethylene oxide exposure in the pSP189 shuttle vector replicated in human Ad293 cells
Keywords: Ethylene oxide; DNA adduct; Mutation; supF
4-Oxo-2-hexenal, a mutagen formed by ω-3 fat peroxidation: Occurrence, detection and adduct formation
Keywords: 4-OHE, 4-oxo-2-hexenal4-Oxo-2-hexenal; Lipid peroxidation; DNA adduct
Vanadium and 1, 25 (OH)2 vitamin D3 combination in inhibitions of 1,2, dimethylhydrazine-induced rat colon carcinogenesis
Keywords: Vanadium; 1, 25 (OH)2 vitamin D3; DMH; DNA adduct; Cell proliferation, Apoptosis
Use of DNA adducts to identify human health risk from exposure to hazardous environmental pollutants: The increasing role of mass spectrometry in assessing biologically effective doses of genotoxic carcinogens
Keywords: Biomarker; Environmental pollutant; Carcinogenesis; DNA adduct; Mass spectrometry
A comparison of covalent binding of ethanol metabolites to DNA according to Aldh2 genotype
Keywords: ALDH2; Polymorphism; Alcohol; Knock-out mouse; DNA adduct
Genotoxic activity and induction of biotransformation enzymes in two human cell lines after treatment by Erika fuel extract
Keywords: Erika oil spill; DNA adduct; Cytochrome P450; HePG2
The effect of feeding piglets with the diet containing green tea extracts or coumarin on in vitro metabolism of aflatoxin B1 by their tissues
Keywords: Green tea; Coumarin; Aflatoxin B1; Pig; Glutathione S-transferase; DNA adduct
DNA adduct formation by the anticancer drug ellipticine in human leukemia HL-60 and CCRF-CEM cells
Keywords: Ellipticine; Human leukemia HL-60 and CCRF-CEM cells; Peroxidases; Cytochromes P450; DNA adduct