دانلود مقالات ISI درباره Etoac + ترجمه فارسی

A triple exon-skipping luciferase reporter assay identifies a new CLK inhibitor pharmacophore

Keywords: CLK; cdc2-like kinase; MDM2; mouse double minute 2 homolog; Luc; luciferase; TEA; triethylamine; DIPEA; diisopropylethylamine; EtOAc; ethyl acetate; Cdc-like kinase (CLK) inhibitors; Modulators of pre-mRNA splicing; High throughput screening; Anti-tumor a

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Structure-activity relationship study of β-oxidation resistant indole-based 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE) receptor antagonists

Keywords: AA; arachidonic acid; 5-HETE; 5-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid; 5-oxo-ETE; 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid; 5-HEDH; 5-hydroxyeicosanoid dehydrogenase; 5-HpETE; 5-hydroperoxyeicosatetraenoic acid; LT; leukotriene; NADP+; nicotinamide

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Characterization of DHDP, a novel aldose reductase inhibitor isolated from Lysimachia christinae

Keywords: 1D; one-dimensional; 2D; two-dimensional; AR; aldose reductase; ARI; aldose reductase inhibitor; BD; binding degree; CH2Cl2; methylene chloride; EALC; the ethyl acetate fraction of Lysimachia christinae methanolic extract; EtOAc; ethyl acetate; FAB-MS; fa

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis and preclinical evaluation of [11C]MA-PB-1 for in vivo imaging of brain monoacylglycerol lipase (MAGL)

Keywords: MAGL; [11C]MA-PB-1; MJN110; Biodistribution; PET imaging; AA; arachidonic acid; AEA; N-arachidonoyl ethanolamine; 2-AG; 2-arachidonoyl glycerol; BBB; blood brain barrier; Bmax; enzyme expression; BBr3; boron tribromide; CB1; cannabinoid 1 receptors; CDCl3

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Anti-inflammatory activity of Crateva adansonii DC on keratinocytes infected by Staphylococcus aureus: From traditional practice to scientific approach using HPTLC-densitometry

Keywords: AUC; area under the curve; BPE; Bovine pituitary extract; DPPH; 2,2-diphenyl-1-picrylhydrazyl free radical; CH2Cl2; methylene chloride; DNI; direct normal irradiation; EDTA; ethylene diamine tetraacetic acid; EGF; epidermal growth factor; EtOAc; ethyl ace

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Effect of sodium salt of Butrin, a novel compound isolated from Butea monosperma flowers on suppressing the expression of SIRT1 and Aurora B kinase-mediated apoptosis in colorectal cancer cells

Keywords: SIRT1; Sirtunin; AURKB; Aurora B kinase; CRC; Colorectal cancer; BMFC; Butea monosperma flower compounds; mRNA; Messenger ribonucleic acid GSK Glycogen synthase kinase; WHO; World health organization; HDAC; Histone deacetylase; CSCs; Cancer stem cells; Bm

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

5-Bromoindirubin 3′-(O-oxiran-2-ylmethyl)oxime: A long-acting anticancer agent and a suicide inhibitor for epoxide hydrolase

Keywords: ATP; adenosine 5′-triphosphate; C1; methylene; C2; ethylene; C3; propylene; CDK; cyclin-dependent kinase; Cys; cysteine residue; DMF; N,N-dimethylformamide; DMSO; dimethyl sulfoxide; EI; electron impact; Epox/5-Br-Ind; 5-bromoindirubin 3′-(O-oxiran-2-

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of spiro[indole-3,2′-pyrrolidin]-2(1H)-one based inhibitors targeting Brr2, a core component of the U5 snRNP

Keywords: CDCl3; deuterated chloroform; DHX29; DEAH-Box helicase 29 (an ATP-dependent RNA helicase); DIPEA; N,N′-diisopropylethylamine; DMSO-d6; dimethyl sulfoxide-d6; EDC·HCl; 1-(3-(dimethylamino)propyl)-3-ethylcarbodiimide hydrochloride; eIF4A1; eukaryotic ini

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Challenges encountered during development of Mn porphyrin-based, potent redox-active drug and superoxide dismutase mimic, MnTnBuOE-2-PyP5 +, and its alkoxyalkyl analogues

Keywords: SOD mimics; Alkoxyalkyl tosylates; Mn N-alkoxyalkylpyridylporphyrins; MnTnBuOE-2-PyP5 + (BMX-001); MnTTEG-2-PyP5 +;  FP-15; Mechanism of pyridyl nitrogen quaternization; SOD; superoxide dismutase;  O2−;  superoxide; MnP; Mn porphyrin; MnTM-2-PyP5 

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2017 سفارش ترجمه

New bis(hydroxymethyl) alkanoate curcuminoid derivatives exhibit activity against triple-negative breast cancer in vitro and in vivo

Keywords: Antiproliferative agents; Antitumor agents; Bis(hydroxymethyl) alkanoate curcuminoids; Curcumin; Triple-negative breast cancer; BUN; blood urea nitrogen; DMAP; N,N-dimethylaminopyridine; DMF; dimethylformamide; DMSO; dimethylsulfoxide; EtOAc; ethyl acetat

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

Improved synthesis of glycine, taurine and sulfate conjugated bile acids as reference compounds and internal standards for ESI-MS/MS urinary profiling of inborn errors of bile acid synthesis

Keywords: EEDQ; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; DEPC; diethyl phosphorocyanidate; DPPA; diphenyl phosphoryl azide; SO3-TEA; sulfur trioxide-triethylamine complex; SO3-TMA; sulfur trioxide-trimethylamine complex; SO3-DMA; sulfur trioxide-N,N-dimethyl

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of selective ATP-competitive eIF4A3 inhibitors

Keywords: RNA helicase; Eukaryotic initiation factor 4A3 (eIF4A3) inhibitors; Exon junction complex (EJC); ATP-competitive type inhibitors; Isothermal titration calorimetry (ITC); Surface plasmon resonance (SPR); BRR2; bad response to refrigeration 2 (an ATP-depend

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2017 سفارش ترجمه

A novel curcumin derivative which inhibits P-glycoprotein, arrests cell cycle and induces apoptosis in multidrug resistance cells

Keywords: ABC; ATP-binding cassette; DMSO; dimethyl sulfoxide; EtOAc; ethyl acetate; EtOH; ethanol; FBS; fetal bovine serum; h; hours; HPLC; high-performance liquid chromatography; HRMS-ESI; high resolution mass spectrometry-electrospray ionization; MDR; multidrug

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2017 سفارش ترجمه

Pronounced anti-proliferative activity and tumor cell selectivity of 5-alkyl-2-amino-3-methylcarboxylate thiophenes

Keywords: Anti-proliferative activity; Tumor selectivity; Gewald reaction; 5-Alkyl-2-aminothiophenes; Intracellular uptake; IC50; 50% inhibitory concentration; THF; tetrahydrofuran; MeOH; methanol; EtOH; ethanol; DMF; dimethylformamide; EtOAc; ethoxyacetate; CNS; c

دانلود رایگان متن کامل مقاله ISI 59 صفحه سال انتشار : 2017 سفارش ترجمه

Simultaneous quantification of PGI2 and TXA2 metabolites in plasma and urine in NO-deficient mice by a novel UHPLC/MS/MS method

Keywords: PGI2; prostacyclin; TXA2; thromboxane A2; IP; PGI receptor; TP; TX receptor; PLA2; phospholipase A2; PGIS; prostacyclin synthase; TXS; thromboxane A synthase; UHPLC/MS/MS; ultra high-performance liquid chromatography coupled to mass spectrometry; TXB2; th

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Structure-based design of a new series of N-(piperidin-3-yl)pyrimidine-5-carboxamides as renin inhibitors

Keywords: AcOH; acetic acid; Ang I; angiotensin I; Ang II; angiotensin II; AUC; area under the blood concentration-time curve; C5min; concentration in plasma 5 min after administration; CLtotal; total clearance; Cmax; maximum concentration in plasma; DIEA; N,N-d

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Isoquercitrin, isolated from Aster yomena triggers ROS-mediated apoptosis in Candida albicans

Keywords: MeOH; methanol; EtOAc; ethyl acetate; CFU; colony-forming unit; ROS; reactive oxygen species; NAC; N-acetylcysteine; H2DCFDA; 2',7'-dichlorodihydrofluorescein diacetate; TUNEL; terminal deoxynucleotidyl transferase dUTP nick end labeling; DAPI; 4',6-diami

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

In vivo effective dibenzo[b,d]furan-1-yl-thiazoles as novel PDE-4 inhibitors

Keywords: PDE; phosphodiesterase; TNF-α; tumour necrosis factor; nm; nanomolar; IL; interleukin; μM; micromolar; @; at; PBMC; peripheral blood mononuclear cells; LPS; lipopolysaccharides; COPD; chronic obstructive pulmonary disease; CC; column chromatography; HCl

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Phenylpropanoids from cinnamon bark reduced β-amyloid production by the inhibition of β-secretase in Chinese hamster ovarian cells stably expressing amyloid precursor protein

Keywords: Cinnamomum cassia; β-Amyloid; Alzheimer disease; β-Secretase; Medioresinol; Cryptamygin A; Aβ40; β-amyloid(1-40); ACN; acetonitrile; AD; Alzheimer disease; APP; amyloid precursor protein; BuOH; butanol; CHO; Chinese hamster ovary; DMSO; dimethyl sulfo

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2016 سفارش ترجمه

Making the case for QuEChERS-gas chromatography of drugs

Keywords: Sample preparation; QuEChERS; Quick, easy, cheap, effective, rugged, and safe; Forensics; Drug extraction; QuEChERS-GC; AA; acetic anhydride; HOAc; acetic acid; ACN; acetonitrile; BPA; bisphenol A; BPB; bisphenol B; C18; octadecylsiloxane; CE; capillary

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Antibacterial effects of Alchornea cordifolia (Schumach. and Thonn.) Müll. Arg extracts and compounds on gastrointestinal, skin, respiratory and urinary tract pathogens

Keywords: ATCC; American type culture collection; CC; column chromatography; CFU; colony forming units; CHCl3; chloroform; COSY; correlation spectroscopy; DCM; dichloromethane; DEPT; distortionless enhancement by polarisation transfer; DMSO; dimethyl sulfoxide; EtO

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2016 سفارش ترجمه

A new enzyme involved in the control of the stereochemistry in the decalin formation during equisetin biosynthesis

Keywords: Biosynthesis; Decalin; Diels-Alder cycloaddition; Fusarium PKS-NRPS hybrid; Secondary metabolite; ATMT; Agrobacterium tumefaciens-mediated transformation; C6; Zn(II)2Cys6-type; ER; enoyl reductase; EtOAc; ethyl acetate; LC/ESI-MS; liquid chromatography/el

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Design, synthesis and evaluation of a gonadotropin releasing hormone-based subunit vaccine in rams (Ovis aries)

Keywords: AcOH; acetic acid; Ac2O; acetic anhydride; ANOVA; analysis of variance; BSA; bovine serum albumin; BW; body weight; C16; 2-amino-d,l-hexadecanoic acids; DCM; dichloromethane; DMF; dimethyl formamide; DIPEA; N,N-diisopropylethylamine; EDTA; ethylenediamine

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Regulation of liver cell glucose homeostasis by dehydroabietic acid, abietic acid and squalene isolated from balsam fir (Abies balsamea (L.) Mill.) a plant of the Eastern James Bay Cree traditional pharmacopeia

Keywords: AMPK; AMP-activated protein kinase; CREB; c-AMP-regulator element-binding protein; EtOAc; ethyl acetate fraction; FoxO1; forkhead transcription factor O1; G6Pase; Glucose-6-Phosphatase; GS; Glycogen Synthase; GSK-3; Glycogen Synthase Kinase-3; Hexane; hex

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Modulatory effect of Senecio brasiliensis (Spreng) Less. in a murine model of inflammation induced by carrageenan into the pleural cavity

Keywords: EtOAc; ethyl acetate fraction; ADA; adenosine-deaminase; AF; alkaloid fraction; CE; crude extract of flowers; CONCEA; National Council of Animal Experimentation Control; DCM; dichloromethane fraction; DCQs; mixture of dicaffeoylquinic acids; Cg; carrageen

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Anti-inflammatory effect of desoxo-narchinol-A isolated from Nardostachys jatamansi against lipopolysaccharide

Keywords: COX-2; cyclooxygenase-2; DN; desoxo-narchinol-A; ELISA; enzyme-linked immunosorbent assay; ERK; extracellular signal-regulated kinase; EtOAc; ethyl acetate; FBS; fetal bovine serum; H&E; hematoxylin and eosin; HPRT; hypoxanthine guanine phosphoribosyl-tra

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Phytochemical characterization and in vitro wound healing activity of leaf extracts from Combretum mucronatum Schum. & Thonn.: Oligomeric procyanidins as strong inductors of cellular differentiation

Keywords: BSTFA-TMS; N,O-bis(trimethylsilyl)trifluoracetamide-trimethylsilylether; CLSM; confocal laser scanning microscopy; EtOH; ethanol; EtOAc; ethyl acetate; HPLC; high pressure liquid chromatography; LDH; lactate dehydrogenase; MeOH; methanol; NHEK; natural hu

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Simple thiol-ene click chemistry modification of SBA-15 silica pores with carboxylic acids

Keywords: Mesostructured materials; Functionalized SiO2; Carboxylic groups; Click chemistry; Thiol-ene addition; SBA-15; PG; post grafting; MSA; mercaptosuccinic acid; MUDA; mercaptoundecanoic acid; MAA; mercaptoacetic acid; TEOS; Tetraethylorthosilicate; EtOAc; et

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis of a mixed-model stationary phase derived from glutamine for HPLC separation of structurally different biologically active compounds: HILIC and reversed-phase applications

Keywords: HPLC; high-performance liquid chromatography; RPLC; reversed-phase liquid chromatography; NPLC; normal-phase liquid chromatography; HILIC; hydrophilic interaction chromatography; DCC; dicyclohexylcarbodiimide; DCM; dichloromethane; H; hexane; EtOAc; ethyl

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Stabilization of cysteine-linked antibody drug conjugates with N-aryl maleimides

Keywords: ADC; antibody-drug conjugate; MMAE; monomethyl-auristatin-E; PAB; p-aminobenzyloxy; mAb; monoclonal antibody; PEG; poly(ethylene glycol); MWCO; molecular weight cut-off; HPLC; high performance liquid chromatography; Q-TOF; Quadrupole-time-of-flight; RP-HP

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

A dual inhibitor of matrix metalloproteinases and a disintegrin and metalloproteinases, [18F]FB-ML5, as a molecular probe for non-invasive MMP/ADAM-targeted imaging

Keywords: ACN; acetonitrile; AcOH; acetic acid; ADAM; a disintegrin and metalloproteinase; CD; catalytic domain; DCC; N,N′-dicyclohexylcarbodiimide; DCM; dichloromethane; DMF; N,N-dimethylformamide; ECM; extracellular matrix; EOB; end of bombardment; EOS; end of

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Sesquiterpene lactones of Moquiniastrum polymorphum subsp. floccosum have antineoplastic effects in Walker-256 tumor-bearing rats

Keywords: ALT; alanine aminotransferase; AST; aspartate aminotransferase; Bax; Bcl-2-associated X protein; Bcl-2; B-cell lymphoma 2; Cat; catalase; DNCB; 2,4-dinitrochlorobenzene; EDTA; ethylenediaminetetraacetic acid; EtOAc; ethyl acetate; F1B; dichloromethane fra

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Evolution and applications of the QuEChERS method

Keywords: 2,4-D; 2,4-dichlorophenoxyacetic acid; ACN; Acetonitrile; Al-N; Alumina neutral; AMPA; Aminomethylphosphonic acid; BDMC; 4-bromo-3,5-dimethylphenyl-N-methylcarbamate; BPA; Bisphenol A; BPB; Bisphenol B; BSA; Bis-(trimethylsilyl)acetamide; C18; Octadecylsi

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2015 سفارش ترجمه

Design, chemical synthesis and biological evaluation of 3-spiromorpholinone/3-spirocarbamate androsterone derivatives as inhibitors of 17β-hydroxysteroid dehydrogenase type 3

Keywords: ADT; androsterone; AR; androgen receptor; Ar; aryl group; DBD; DNA binding domain; DCM; dichloromethane; DHT; dihydrotestosterone; DIPEA; N,N-diisopropylethylamine; DMF; dimethylformamide; DMSO; dimethylsulfoxide; Δ4-dione; 4-androstene-3,17-dione; EtOAc

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2015 سفارش ترجمه

Pentacyclic triterpene derivatives possessing polyhydroxyl ring A inhibit Gram-positive bacteria growth by regulating metabolism and virulence genes expression

Keywords: Pentacyclic triterpene derivatives; Polyhydroxyl ring A; Synthesis; Antibacterial activity; Mechanism; UA; ursolic acid; OA; oleanolic acid; S. aureus; Staphylococcus aureus; E. coli; Escherichia coli; S. scabies; Streptomyces scabies; R. solanacearum

دانلود رایگان متن کامل مقاله ISI 93 صفحه سال انتشار : 2015 سفارش ترجمه

Research PaperPallidifloside D, a saponin glycoside constituent from Smilax riparia, resist to hyperuricemia based on URAT1 and GLUT9 in hyperuricemic mice

Keywords: mURAT1; mouse Urate Transporter 1; mGLUT9; mouse Glucose Transporter 9; mOAT1; mouse Organic Anion Transporter 1; mGAPDH; mouse Glyceraldehyde-3-phosphate dehydrogenase; EtOH; Ethyl alcohol; BuOH; n-Butyl alcohol; EtOAc; Ethyl acetate; HR-ESI-MS; High-Res

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

The antioxidant properties of new dimer and two monomers of phenolic acid amides isolated from Limoniastrum guyonianum

Keywords: DPPH; 2,2-Diphenyl-1-picrylhydrazyl; IC50; inhibition concentration at 50 percent; EC50; effective concentration at which the absorbance was 0.5; BHT; butylated hydroxytoluene; BHA; butylated hydroxyanisole; n-hept; n-heptane; EtOAc; ethyl acetate; MeOH;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Aculeatin, a coumarin derived from Toddalia asiatica (L.) Lam., enhances differentiation and lipolysis of 3T3-L1 adipocytes

Keywords: ACN; acetonitrile; BSA; bovine serum albumin; BuOH; butanol; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; EDTA; ethylenediaminetetraacetic acid; EtOAc; ethyl acetate; ext.; extract; FBS; fetal bovine serum; GPDH; glycerol-3-phos

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Anti-inflammatory activity of omphalocarpin isolated from Radix Toddaliae Asiaticae

Keywords: NO; nitric oxide; TNF-α; tumor necrosis factor; IL-6; interleukin-6; iNOS; inducible nitric oxide synthase; COX-2; cyclooxygenase-2; NF-κB; nuclear factor-kappa B; LPS; lipopolysaccharide; DMEM; Dulbecco׳s modified Eagle׳s minimum essential medium; FB

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibitory effects of Pleurotus tuber-regium mycelia and bioactive constituents on LPS-treated RAW 264.7 cells

Keywords: cDNA; complementary DNA; COX2; cyclooxygenase 2; DMEM; Dulbecco's modified Eagle's medium; ELISA; enzyme-linked immunosorbent assay; EtOAc; ethyl acetate; FBS; fetal bovine serum; IL; interleukin; iNOS; inducible NOS; LPS; lipopolysaccharide; MTT; 3-(

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Synthesized quercetin derivatives stimulate melanogenesis in B16 melanoma cells by influencing the expression of melanin biosynthesis proteins MITF and p38 MAPK

Keywords: α-MSH; α-melanocyte-stimulating hormone; BSA; bovine serum albumin; cAMP; cyclic adenosine monophosphate; DMEM; Dulbecco's modified Eagle medium; DMF; dimethylformamide; l-DOPA; l-3,4-dihydroxyphenylalanine; ECL; enhanced chemiluminescence; EtOAc; eth

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Potential of novel phytoecdysteroids isolated from Vitex doniana in the treatment depression: Involvement of monoaminergic systems

Keywords: DMSO; dimethylsulfoxide; MDD; major depressive disorder; 5-HT; serotonin; FST; forced swim test; TST; tail suspension test; VD; Vitex doniana; C1; 21-hydroxyshidasterone; C2; 11β-hydroxy-20-deoxyshidasterone C3-2; 3-acetonide; 24-hydroxyecdysone; C4; shi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Structure-based design, synthesis and biological testing of etoposide analog epipodophyllotoxin-N-mustard hybrid compounds designed to covalently bind to topoisomerase II and DNA

Keywords: Boc2O; di-tert-butyl dicarbonate; CHO; Chinese hamster ovary; Et3N; triethylamine; EtOAc; ethyl acetate; HOBt; (1-hydroxybenzotriazole); ICE; immunodetection of complexes of enzyme-to-DNA; K562 cells; human erythroleukemic cells; kDNA; catenated DNA; MTS;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

Discovery and optimization of novel small-molecule HIV-1 entry inhibitors using field-based virtual screening and bioisosteric replacement

Keywords: ADME; absorption, distribution, metabolism, and excretion; AMLV; amphotropic murine leukemia virus; BBB; blood-brain barrier; BIF; bioisostere factor; CNS; central nervous system; DCM; dichloromethane; DiEA; diisopropylethylamine; DIPEA; N,N-diisopropyl

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2014 سفارش ترجمه

The Canadian medicinal plant Heracleum maximum contains antimycobacterial diynes and furanocoumarins

Keywords: [α]D; specific rotation measured at 589 nm and the temperature indicated; 1D; one dimensional; 2D; two dimensional; ACS; American Chemical Society; bs; broad singlet; c; concentration in g/100 mL; CH2Cl2; dichloromethane; d; doublet; DMSO; dimethyl sul

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Antimicrobial and acetylcholinesterase inhibitory activities of Buddleja salviifolia (L.) Lam. leaf extracts and isolated compounds

Keywords: 4-NQO; 4-nitroquinoline-N-oxide; AChE; acetylcholinesterase; AD; Alzheimer's disease; ATCC; American type culture collection; ATCI; acetylthiocholine iodide; BuOH; butanol; CFU; colony forming unit; DCM; dichloromethane; DEPT; distortionless enhancement o

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Discovery and SAR studies of methionine-proline anilides as dengue virus NS2B-NS3 protease inhibitors

Keywords: HQRJJHXKCFABSI-UONOGXRCSA-N; SAR; structure and activity relationship; NS2B-NS3; nonstructural protein 2B and 3; DENV; dengue virus; Ki; inhibition constant; TFA; trifluoroacetic acid; EtOAc; ethyl acetate; DCM; dichloromethylene; EtOH; ethyl alcohol; DMA

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Antifungal property of hibicuslide C and its membrane-active mechanism in Candida albicans

Keywords: Hibicuslide C; Membrane-active mechanism; Phytochemical; Antifungal effect; Candida albicans; MeOH; methanol; CH2Cl2; dichloromethane; EtOAc; ethyl acetate; ATCC; American Type Culture Collection; KCTC; Korean Collection For Type Cultures; MIC; minimum in

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Sasanquasaponin from Camellia oleifera Abel. induces cell cycle arrest and apoptosis in human breast cancer MCF-7 cells

Keywords: SQS; sasanquasaponin; HPLC; high-performance liquid chromatography; RP-HPLC; reversed-phase high-performance liquid chromatography; EtOAc; ethyl acetate; BuOH; n-butanol; DMEM; Dulbecco's modified Eagle's medium; NEAA; nonessential amino acids; MTT; 3-[4,

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Icariin from Epimedium brevicornum Maxim promotes the biosynthesis of estrogen by aromatase (CYP19)

Keywords: ELISA; enzyme-linked immunosorbent assay; qRT-PCR; quantitative real-time reverse-transcription polymerase chain reaction; ER; estrogen receptor; SERM; selective estrogen receptor modulator; cAMP; cyclic adenosine monophosphate; ALP; alkaline phosphatase;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه