دانلود مقالات ISI درباره Farnesoid X گیرنده + ترجمه فارسی

Alisma orientale extract exerts the reversing cholestasis effect by activation of farnesoid X receptor

Keywords: Farnesoid X گیرنده; Alisma orientale; Cholestasis; Proteomics; Farnesoid X receptor; AOE; Alisma orientale extract; ANIT; α-naphthylisothiocyanate; FXR; farnesoid X receptor; AST; aspartate aminotransferase; ALT; alanine aminotransferase; TBIL; total bilirubin; TBA; intrahe

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Significance of A-to-I RNA editing of transcripts modulating pharmacokinetics and pharmacodynamics

Keywords: Farnesoid X گیرنده; ABC; ATP-binding cassette transporter; ADAR; adenosine deaminase acting on RNA; ADH; alcohol dehydrogenase; AhR; aryl hydrocarbon receptor; AKR; aldo-keto reductase; ALS; amyotrophic lateral sclerosis; AZIN1; antizyme inhibitor 1; AMPA; α-amino-3-hydroxy

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Bile acids and FXR in functional gastrointestinal disorders

Keywords: Farnesoid X گیرنده; Bile acids; Chronic constipation; Farnesoid X receptor; Irritable bowel syndrome;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Protective effect of dioscin against doxorubicin-induced cardiotoxicity via adjusting microRNA-140-5p-mediated myocardial oxidative stress

Keywords: Farnesoid X گیرنده; AMPK; adenosine 5'-monophosphate (AMP)-activated protein kinase; CK; creatine kinase; DAPI; 4',6'-Diamidino-2-phenylindole; DOX; doxorubicin; ECG; electrocardiograms; FOXO3a; Forkhead box O3; FXR; farnesoid X receptor; GCLM; glutamatecysteine ligase mod

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Differential effects of FXR or TGR5 activation in cholangiocarcinoma progression

Keywords: Farnesoid X گیرنده; BA; bile acid; CCA; cholangiocarcinoma; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum; FXR; farnesoid X receptor; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GPBAR1 (or TGR5); G protein-coupled bile acid receptor 1; MRI; magnetic

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

PDZ domain containing protein 1 (PDZK1), a modulator of membrane proteins, is regulated by the nuclear receptor THRβ

Keywords: Farnesoid X گیرنده; Thyroid hormones; Scaffold protein; PDZ-domain; Gene regulation; Thyroid hormone receptors; 5-HT2A; Serotonin 2A receptor; ABC; ATP-binding cassette transporter; AhR; Transcription factor aryl hydrocarbon receptor; BCRP; Breast cancer resistance protein;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

The ileum-liver Farnesoid X Receptor signaling axis mediates the compensatory mechanism of 17α-ethynylestradiol-induced cholestasis via increasing hepatic biosynthesis of chenodeoxycholic acids in rats

Keywords: Farnesoid X گیرنده; Asbt; apical sodium-dependent bile acids transporter; ALP; alkaline phosphatase; ALT; alanine transaminase; AST; aspartate transaminase; BAs; bile acids; Bsep/BSEP; bile salt export pump; β-MCA; β-muricholic acid; CA; cholic acid; CDCA; chenodeoxycholic

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Takeda G Protein-Coupled Receptor 5-Mechanistic Target of Rapamycin Complex 1 Signaling Contributes to the Increment of Glucagon-Like Peptide-1 Production after Roux-en-Y Gastric Bypass

Keywords: Farnesoid X گیرنده; BAs; Bile acids; Cyp7a1; Cytochrome P450 family 7 subfamily A member 1; DCA; Deoxycholic acid; FXR; Farnesoid X receptor; GLP-1; Glucagon-like peptide-1; ip; Intraperitoneal; mTOR; mechanistic target of rapamycin; mTORC1; mechanistic target of rapamycin c

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Intestinal Farnesoid X Receptor Activation by Pharmacologic Inhibition of the Organic Solute Transporter α-β

Keywords: Farnesoid X گیرنده; Fluorescence Resonance Energy Transfer (FRET); FXR; OSTα-OSTβ; Bile Acids; ASBT; apical sodium-dependent bile acid transporter; BAS; bile acid sensor; FACS; fluorescence-activated cell sorting; FDA; Food and Drug Administration; FGF15/19; fibroblast gro

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Ablating both Fabp1 and Scp2/Scpx (TKO) induces hepatic phospholipid and cholesterol accumulation in high fat-fed mice

Keywords: Farnesoid X گیرنده; 3αHSD; 3alpha-hydroxysteroid reductase; ABCA1; ATP-binding cassette sub-family A member 1; ABCG1; 4, 5 or 8, ATP-binding cassette sub-family G member 1,4, 5 or 8; ACAT2; acetyl-CoA acetyltransferase (Soat2 gene); ACC1; acetyl-CoA carboxylase (Acaca gene)

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

Current Treatment Options for Primary Biliary Cholangitis

Keywords: Farnesoid X گیرنده; Autoimmune liver disease; Therapy; Bile acids; Farnesoid X receptor;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

An FXR Agonist Reduces Bile Acid Synthesis Independently of Increases in FGF19 in Healthy Volunteers

Keywords: Farnesoid X گیرنده; Liver; CYP7A1; Nuclear Receptor Subfamily 1 Group H Member 4; NR1H4; BA; bile acid; C4; 7α-hydroxy-4-cholesten-3-one; CDCA; chenodeoxycholic acid; CYP7A1; cholesterol 7α-hydroxylase; FGF; fibroblast growth factor; FXR; farnesoid X receptor; LDL; low-den

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Ubiquitination/sumoylation: An alternative pathway to modify gene regulation directed by xenosensors

Keywords: Farnesoid X گیرنده; Epigenetic regulation; Post-translational modifications; Nuclear receptors; Xenobiotics metabolism; AHR; aryl hydrocarbon receptor; AHRR; aryl hydrocarbon receptor repressor; ARNT; aryl hydrocarbon receptor nuclear translocator; CAR; constitutive androsta

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Molecular cloning and characterization of farnesoid X receptor from large yellow croaker (Larimichthys crocea) and the effect of dietary CDCA on the expression of inflammatory genes in intestine and spleen

Keywords: Farnesoid X گیرنده; Farnesoid X receptor; Chenodeoxycholic acid; Larimichthys crocea;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

Cholestatic Alterations in the Critically Ill

Keywords: Farnesoid X گیرنده; bile acids; bilirubin; cholestasis; critical illness; liver; sepsis; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; BA; bile acid; FXR; farnesoid X receptor; γ-GT; γ-glutamyl transpeptidase; INR; international

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Synbiotics Bifidobacterium infantis and milk oligosaccharides are effective in reversing cancer-prone nonalcoholic steatohepatitis using western diet-fed FXR knockout mouse models

Keywords: Farnesoid X گیرنده; ALT; alanine transferases; ALP; alkaline phosphatase; BA; bile acid; bcoA; butyryl-coenzyme-A-CoA transferase; buk; butyrate kinase; B. infantis; Bifidobacterium longum subsp. infantis; CA; cholic acid; CDCA; chenodeoxycholic acid; DCA; deoxycholic acid;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Effects of farnesoid-X-receptor SUMOylation mutation on myocardial ischemia/reperfusion injury in mice

Keywords: Farnesoid X گیرنده; Nuclear receptor; Farnesoid X receptor; Ischemia-reperfusion; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Bioactive Lipid Species and Metabolic Pathways in Progression and Resolution of Nonalcoholic Steatohepatitis

Keywords: Farnesoid X گیرنده; Nonalcoholic Fatty Liver Disease; Triglycerides; Fatty Acids; Therapy; AA; arachidonic acid; ACC; acetyl-coenzyme A carboxylase; ASMase; acid sphingomyelinase; CeS; ceramide synthase; CoA; coenzyme A; COX; cyclo-oxygenase; DES; dihydro-ceramide desatura

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Reversal of metabolic disorders by pharmacological activation of bile acid receptors TGR5 and FXR

Keywords: Farnesoid X گیرنده; Farnesoid X receptor; TGR5; Atherosclerosis; Obesity; NAFLD; α-Sma; alpha smooth muscle actin (α-Sma); BA; bile acid; BAT; brown adipose tissue; CEBPα; CCAAT/enhancer-binding protein α; Col1α1; collagen type 1 α1; DIO; diet-induced obesity; FXR; far

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Nuclear receptor FXR, bile acids and liver damage: Introducing the progressive familial intrahepatic cholestasis with FXR mutations

Keywords: Farnesoid X گیرنده; NR; nuclear receptor; FXR; farnesoid X receptor; RXR; retinoid X receptor; PXR; pregnane X receptor; VDR; Vitamin D receptor; TGR5; G protein-coupled bile acid receptor; Lrh1; liver receptor homolog 1; Mdr; multidrug resistance protein; Abcb4; ATP Bindi

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Mechanisms of MAFG Dysregulation in Cholestatic Liver Injury and Development of Liver Cancer

Keywords: Farnesoid X گیرنده; FXR; Obeticholic Acid; S-Adenosylmethionine; Ursodeoxycholic Acid; AP-1; activator protein-1; ARE; antioxidant response element; BDL; bile duct ligation; BrdU; 5-bromo-2'deoxyuridine; CCA; cholangiocarcinoma; FXR; farnesoid X receptor; GSH; reduced glut

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Activation of PPARα decreases bile acids in livers of female mice while maintaining bile flow and biliary bile acid excretion

Keywords: Farnesoid X گیرنده; Biliary excretion; PPARα; Bile acids; Gender difference; 1oBAs; Primary bile acids; 2oBAs; secondary bile acids; 12-OH; 12-hydroxylated bile acid; Asbt; apical sodium-dependent bile acid transporter; BA; bile acid; Baat; bile acid CoA:amino acid N-acyltr

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Transhepatic bile acid kinetics in pigs and humans

Keywords: Farnesoid X گیرنده; Bile acids; TGR5; Porcine; Postprandial; Portal concentrations; BAs; bile acids; ASBT; apical sodium-dependent bile acid transporter; OST; organic solute transporter; NTCP; taurocholate cotransporting polypeptide; OATP; organic anion transporting polypept

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Microcystin induction small Maf protein involve in transcriptional regulation of GST from freshwater mussel Cristaria plicata

Keywords: Farnesoid X گیرنده; Maf; musculoaponeurotic fibrosarcoma; GST; glutathione S-transferase; ARE; antioxidant response element; EpRE; electrophile response element; CNC; cap “n” collar; bZIP; basic region leucine zipper; Nrf2; nuclear factor erythroid-2p45-related factor 2;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Cholemic nephropathy - Historical notes and novel perspectives

Keywords: Farnesoid X گیرنده; AKI; acute kidney injury; CBDL; common bile duct ligation; CKD; chronic kidney disease; CN; cholemic nephropathy; FXR; farnesoid X receptor; GFR; glomerular filtration rate; IL-18; interleukin 18; iNOS; inducible nitric oxide synthase; KDIGO; Kidney Disea

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Human-based systems: Mechanistic NASH modelling just around the corner?

Keywords: Farnesoid X گیرنده; Elafibranor (PubChem CID: 9864881); Obeticholic acid (PubChem CID: 447715); Pioglitazone (PubChem CID: 4829); Rosiglitazone (PubChem CID: 77999); Fenofibrate (PubChem CID: 3339); Serine (PubChem CID: 5951); ACC1; acetyl-coenzyme A carboxylase 1; AdipoR; a

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Aryl hydrocarbon receptor (AhR) mediated short-term effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on bile acid homeostasis in mice

Keywords: Farnesoid X گیرنده; Aryl hydrocarbon receptor; TCDD; Bile acids; Biliary excretion; Taurodeoxycholic acid; Cyp8b1; 1°BAs; Primary bile acids; 2°BAs; Secondary bile acids; 6-OH; 6-hydroxylated (6-OH); 12-OH; 12α-hydroxylated; Abc; ATP-binding cassette; AhR; Aryl hydrocarbo

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2018 سفارش ترجمه

Non-alcoholic fatty liver disease and its treatment with n-3 polyunsaturated fatty acids

Keywords: Farnesoid X گیرنده; NAFLD; Omega-3 fatty acids; Fish oil; Algal oil; Insulin resistance; Metabolic syndrome; ALA; alpha-linolenic acid; ALT; alanine aminotransferase; Apo; apolipoprotein; AST; aspartate aminotransferase; BMI; body mass index; ChREBP; carbohydrate response el

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2018 سفارش ترجمه

Tithonia diversifolia (Hemsl.) A. Gray as a medicinal plant: A comprehensive review of its ethnopharmacology, phytochemistry, pharmacotoxicology and clinical relevance

Keywords: Farnesoid X گیرنده; ABTS; 2,2′-Azinobis (3-ethylbenzothiazoline-6-sulphonate); Ach; acetyl choline; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AMPK; 5' adenosine monophosphate-activated protein kinase; AST; Aspartate transaminase; CAs; chlorogenic acids; CC5

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2018 سفارش ترجمه

Insights into hepatic and renal FXR/DDAH-1/eNOS pathway and its role in the potential benefit of rosuvastatin and silymarin in hepatic nephropathy

Keywords: Farnesoid X گیرنده; Cirrhosis; DDAH-1; FXR; Kidney; Rosuvastatin; Silymarin; ADMA; asymmetric dimethylarginine; ALK; Alkaline phosphatase; ALT; alaninetransaminase; AST; aspartate transaminase; CRD; Chronic Renal Disease; DDAH; dimethylarginine dimethylaminohydrolase-; ED; E

دانلود رایگان متن کامل مقاله ISI 65 صفحه سال انتشار : 2018 سفارش ترجمه

Natural products as modulators of the nuclear receptors and metabolic sensors LXR, FXR and RXR

Keywords: Farnesoid X گیرنده; Natural products; Nuclear receptors; Liver X receptor; Farnesoid X receptor; Retinoid X receptor; Metabolic syndrome; Precision medicine; 6-ECDCA; 6α-ethyl-chenodeoxycholic acid (obeticholic acid); AA; arachidonic acid; ABC; ATP-binding cassette transpor

دانلود رایگان متن کامل مقاله ISI 78 صفحه سال انتشار : 2018 سفارش ترجمه

Autophagy in ischemic stroke

Keywords: Farnesoid X گیرنده; 3-MA; 3-methyladenine; Aβ; amyloid β; AIF; apoptosis-inducing factor; Akt; protein kinase B; AMPK; AMP-activated protein kinase; ATF6; activating transcription factor 6; Atg; autophagy-related genes; ATP; adenosine 5′-triphosphate; BBB; blood-brain ba

دانلود رایگان متن کامل مقاله ISI 78 صفحه سال انتشار : 2018 سفارش ترجمه

Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2)

Keywords: Farnesoid X گیرنده; NASH; Nrf2; TBE-31; ACACA; acetyl-CoA carboxylase alpha; ACLY; ATP citrate lyase; ACOT7; acetyl-CoA thioesterase 7; ACOX2; acetyl-CoA oxidase 2; ADRP; adipose differentiation-related protein; AP-1; activator protein 1; ApoB; apolipoprotein B; ATF4; activa

دانلود رایگان متن کامل مقاله ISI 79 صفحه سال انتشار : 2018 سفارش ترجمه

Design, synthesis and metabolic regulation effect of farnesoid X receptor (FXR) antagonistic benzoxepin-5-ones

Keywords: Farnesoid X گیرنده; Farnesoid X receptor; Antagonist; Benzoxepin-5-one; Triglyceride; Plasma ALT;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

A novel intestinal-restricted FXR agonist

Keywords: Farnesoid X گیرنده; Farnesoid X receptor; Agonist; Intestinal-restricted; Fexaramine;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis and biological evaluations of chalcones, flavones and chromenes as farnesoid x receptor (FXR) antagonists

Keywords: Farnesoid X گیرنده; Farnesoid X receptor; Antagonist; Chalcones; Chromenes;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery and optimization of benzimidazole derivatives as a novel chemotype of farnesoid X receptor (FXR) antagonists

Keywords: Farnesoid X گیرنده; FXR; farnesoid X receptor; CDCA; chenodeoxycholic acid; CYP7A1; cholesterol 7α-hydroxylase; SHP; small heterodimer partner; RXRα; retinoid X receptor α; 9-cis-RA; 9-cis-retinoic acid; LBD; ligand binding domain; TR-FRET; time-resolved fluorescence reso

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Circadian rhythmicity: A functional connection between differentiated embryonic chondrocyte-1 (DEC1) and small heterodimer partner (SHP)

Keywords: Farnesoid X گیرنده; DEC1; BHLHE40; SHP; NR0B2; Circadian rhythm; AMPK; 5′ AMP-activated protein kinase; Bmal1; Brain and muscle ARNT-like 1; Clock; circadian locomotor output cycles kaput; Cry; Cryptochrome; CYP7A1; Cytochrome P450 enzyme cholesterol 7α-hydroxylase; DEC;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Farnesoid X receptor agonist GW4064 ameliorates lipopolysaccharide-induced ileocolitis through TLR4/MyD88 pathway related mitochondrial dysfunction in mice

Keywords: Farnesoid X گیرنده; Farnesoid X receptor; GW4064; Inflammatory bowel disease; Toll-like receptor 4; Mitochondrial dysfunction;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

The emerging role of AMP-activated protein kinase in cholestatic liver diseases

Keywords: Farnesoid X گیرنده; AMPK; AMP-activated protein kinase; PSC; primary sclerosing cholangitis; LKB1; Liver Kinase B1; CamKKβ; Ca2+-calmodulin-activated protein kinase beta; ERK1/2; extracellular signal-regulated kinase 1/2; FXR; farnesoid X receptor; BSEP; bile salt export pu

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Prevention of cholesterol gallstone disease by schaftoside in lithogenic diet-induced C57BL/6 mouse model

Keywords: Farnesoid X گیرنده; Schaftoside (PubChem CID:442658); Ursodeoxycholic acid (PubChem CID:31401); Schaftoside; Lithogenic diet; Cholesterol gallstone; Liver X receptor α; Farnesoid X receptor;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Calycosin attenuates triglyceride accumulation and hepatic fibrosis in murine model of non-alcoholic steatohepatitis via activating farnesoid X receptor

Keywords: Farnesoid X گیرنده; Calycosin; Farnesoid X receptor; Non-alcoholic steatohepatitis; Triglyceride accumulation; Hepatic fibrosis; a-SMA; a-smooth muscle actin; ALT; alanine aminotransferase; AST; aspartate transaminase; ACC; acetyl-coenzyme A carboxylase; CPT1; carnitine palm

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Farnesoid X Receptor Agonist Treatment Alters Bile Acid Metabolism but Exacerbates Liver Damage in a Piglet Model of Short-Bowel Syndrome

Keywords: Farnesoid X گیرنده; Short-Bowel Syndrome; Liver Disease; Intestinal Failure-Associated Liver Disease; Obeticholic Acid; Bile Acids; Farnesoid X Receptor; FXR; farnesoid X receptor; OCA; obeticholic acid; CDCA; chenodeoxycholic acid; FGF19; fibroblast growth factor-19; HCA;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Pregnane X receptor regulates the AhR/Cyp1A1 pathway and protects liver cells from benzo-[α]-pyrene-induced DNA damage

Keywords: Farnesoid X گیرنده; PXR; pregnane X receptor; AhR; aryl hydrocarbon receptor; DRE; dioxin response element; BaP; benzo[a]pyrene; RIF; rifampicin; H2Ax; histone 2Ax; CAR; constitutive androstane receptor; FXR; farnesoid X receptor; CYP450; cytochrome P450; EROD; 7-ethoxyresor

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Thyroid stimulating hormone exhibits the impact on LDLR/LDL-c via up-regulating hepatic PCSK9 expression

Keywords: Farnesoid X گیرنده; SCH; subclinical hypothyroidism; TC; total cholesterol; LDL-c; low-density lipoprotein cholesterol; TSH; thyroid stimulating hormone; TSHR; thyroid stimulating hormone receptor; HMGCR; 3-hydroxy-3-methylglutaryl-CoA reductase; PCSK9; proprotein convertase

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Relationship between NR1I2 polymorphisms and inflammatory bowel disease risk: A systematic review and meta-analysis

Keywords: Farnesoid X گیرنده; NR1I2; Homo sapiens nuclear receptor subfamily 1 group I member 2; IBD; inflammatory bowel diseases; UC; Ulcerative Colitis; CD; Crohn's Disease; OR; odd radio; CI; confidence interval; PPARα; peroxisome proliferator-activated receptor alpha; FXR; farnes

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

The FXR agonist PX20606 ameliorates portal hypertension by targeting vascular remodelling and sinusoidal dysfunction

Keywords: Farnesoid X گیرنده; Farnesoid X receptor; FXR agonist; PX20606; Portal hypertension; Fibrosis; Cirrhosis; Bacterial translocation; Intestinal permeability; Rat; Mouse;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor

Keywords: Farnesoid X گیرنده; BA; bile acid; CA; cholic acid; CDCA; chenodeoxycholic acid; CYP; cytochrome P450; DCA; deoxycholic acid; 6-ECDCA; 6α-ethyl-chenodeoxycholic acid, obeticholic acid; FXR; farnesoid X receptor; LBD; ligand binding domain; LCA; lithocholic acid; PXR; pregna

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Anti-hyperlipidemic effects of Rhizoma Coptidis alkaloids are achieved through modulation of the enterohepatic circulation of bile acids and cross-talk between the gut microbiota and the liver

Keywords: Farnesoid X گیرنده; ASBT; apical sodium-dependent bile salt transporter; BSEP; bile salt export pump; COX2; cyclooxygenase 2; CYP7A1; cholesterol 7α-hydroxylase; FXR; farnesoid X receptor; HFHC; high fat and high cholesterol; HMGCR; 3-hydroxy-3-methyl glutaryl coenzyme A re

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of pentacyclic triterpene 3β-ester derivatives as a new class of cholesterol ester transfer protein inhibitors

Keywords: Farnesoid X گیرنده; CETP inhibitor; Pentacyclic triterpenes; Non-HDL-C; Dyslipidemia; CVDs; cardiovascular diseases; CETP; cholesteryl ester transfer protein; HDL-C; high density lipoprotein-cholesterol; LDL-C; low density lipoprotein-cholesterol; VLDL; very-low-density lipo

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه