Keywords: B2M; beta-2-microglobulin; BMI; body mass index; CCL; chemokine (C-C motif) ligand; cDNA; complimentary deoxyribonucleic acid; CXCL16; chemokine (C-X-C motif) ligand 16; DPP4; dipeptidyl-peptidase 4; DXA; dual energy X-ray absorptiometry; g; gravity; Gadd
مقالات ISI (ترجمه نشده)
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Keywords: FOXO; forkhead box O; GC; glucocorticoids; MuRF-1; muscle RING-finger protein-1; mTOR; mammalian target of rapamycin; IGF-I; Insulin-like Growth Factor-I; eIF4E; eukaryotic translation initiation factor 4E; S6K1; ribosomal protein kinase 1; 4E-BP1; eukary
Role of Forkhead Box O (FOXO) transcription factor in aging and diseases
Keywords: FOXO; Forkhead box O; DBD; DNA-binding domain; NLS; Nuclear localization sequence; NES; Nuclear export sequence; IRE; Insulin-responsive element; ARDs; Age-related diseases; RTK; Receptor tyrosine kinase; PI3K; Phosphoinositide 3kinase; SGK; Serum and glu
Sumoylation and ubiquitylation crosstalk in the control of ÎNp63α protein stability
Keywords: SUMO; Small Ubiquitin-like Modifier; Ub; ubiquitin; SHFM-IV; Split Hand Foot Malformation; Ubc9; ubiquitin carrier protein 9; p14ARF; p14 Alternative Reading Frame; GAM-1; Gallus Anti Mortem 1; GADD45; The Growth Arrest and DNA Damage; DLX5; Distal-Less H
The FOXO3-FOXM1 axis: A key cancer drug target and a modulator of cancer drug resistance
Keywords: ABCB1; ATP-binding cassette sub-family B member 1; AML; acute myeloid leukaemia; AMPK; adenosine monophosphate-activated protein kinase; ATM; Ataxia-telangiectasia mutated; AURKA; aurora kinase A; BER; base excision repair; Bim; B-cell lymphoma 2 interact
Novel CIL-102 derivatives as potential therapeutic agents for docetaxel-resistant prostate cancer
Keywords: CIL-102 derivatives; CR PCa; Docetaxel-resistant cancer; Anti-microtubule agents; Selectivity; Androgen deprivation therapy; ADT; Androgen-independent; AI; Androgen receptor; AR; Androgen-sensitive; AS; Castration-Resistant Prostate Cancer; CRPC; dichloro
GADD45 family proteins suppress JNK signaling by targeting MKK7
Keywords: GADD45; Heat shock; HSF1; JNK; MKK7;
Growth arrest and DNA damage-inducible 45α protects against nonalcoholic steatohepatitis induced by methionine- and choline-deficient diet
Keywords: NASH; nonalcoholic steatohepatitis; FA; fatty acid; DG; diacylglycerol; ER; endoplasmic reticulum; Gadd45; growth arrest and DNA damage-inducible 45; DMBA; dimethylbenzanthracene; WT; wild-type; ATF; activating transcription factor; MCD; methionine- and c
G2/M cell cycle arrest on HT-29 cancer cells and toxicity assessment of triphenylphosphanegold(I) carbonimidothioates, Ph3PAu[SC(OR)Â =Â NPh], RÂ =Â Me, Et, and iPr, during zebrafish development
Keywords: Annexin V-FITC; Recombinant annexin V conjugated to fluorescein isothiocyanate; APAF-1; Apoptotic protease activating factor 1; ATR; Ataxia telangiectasia and Rad3-related; Bax; Apoptosis regulator; Bcl-2; B-cell lymphoma 2; BIRC-5; Baculoviral inhibitor
GADD45 proteins inhibit HIV-1 replication through specific suppression of HIV-1 transcription
Keywords: GADD45; HIV-1; LTR; Transcription; Latency;
Rhododenol and raspberry ketone impair the normal proliferation of melanocytes through reactive oxygen species-dependent activation of GADD45
Keywords: Rhododenol; Raspberry ketone; B16F10 cell; Human melanocytes; GADD45;
Stimulation of ribosomal RNA gene promoter by transcription factor Sp1 involves active DNA demethylation by Gadd45-NER pathway
Keywords: ChIP; chromatin immunoprecipitation; NER; nucleotide excision repair; NoRC; nucleolar remodeling complex; PBS; phosphate-buffered saline; Pol I; RNA polymerase I; qRT-PCR; quantitative real time-polymerase chain reaction; rDNA; ribosomal DNA; Sp1; Specifi
Protection against phalloidin-induced liver injury by oleanolic acid involves Nrf2 activation and suppression of Oatp1b2
Keywords: ALT; alanine aminotransferase; Gadd45; growth arrest DNA damage response protein 45; OA; oleanolic acid; Nrf2; Nuclear factor erythroid-derived 2-like 2; NQO1; NAD(P)H quinone oxidoreductase 1; p-JNK; phosphorylated c-jun N-terminal kinase; TBARS; thiobar
GADD45a physically and functionally interacts with TET1
Keywords: Gadd45; TET; DNA demethylation; LC-MS/MS; hmC;
Amyloidogenic lysozymes accumulate in the endoplasmic reticulum accompanied by the augmentation of ER stress signals
Keywords: Armet; arginine-rich, mutated in early stage tumors; ATF4; activating transcription factor 4, a PERK downstream target; ATF6α; activating transcription factor 6α; CHOP; C/EBP homologous protein; DAPI; diamidino-2-phenylindole; EDEM1; ER degradation-enha
Comparative analysis of developmentally regulated expressions of Gadd45a, Gadd45b, and Gadd45g in the mouse and marmoset cerebral cortex
Keywords: AP; alkaline phosphatase; DAPI; 4â²,6-diamidino-2-phenylindole; DIG; digoxigenin; Ent; entorhinal cortex; Gadd45; growth arrest and DNA damage-inducible protein 4; GW; gestational week; Hp; hippocampus; Is; insula; PBS; phosphate-buffered saline; PFA; pa
The impact of R213 mutation on p53-mediated p21 activity
Keywords: p53; Mutation; Arginine; p21; WAF1; wild-type p53-activated fragment 1; MDM2; mouse double minute 2 homolog; GADD45; the growth arrest and DNA damage-inducible 45; Bax; Bcl-2-associated X protein; PRMT5; protein arginine methyltransferase 5; DMEM; Dulbecc
Silencing of PKCη induces cycle arrest of EBV+ B lymphoma cells by upregulating expression of p38-MAPK/TAp73/GADD45α and increases susceptibility to chemotherapeutic agents
Keywords: EBV; Epstein-Barr virus; MAPKs; mitogen-activated protein kinases; GADD45; growth arrest and DNA damage-inducible gene 45; TAp73; transcriptionally active p73; PKCη; p38-MAPK; TAp73; GADD45α; Cell cycle arrest; EBV+ lymphoma;
Anti-proliferative effect of (19Z)-halichondramide, a novel marine macrolide isolated from the sponge Chondrosia corticata, is associated with G2/M cell cycle arrest and suppression of mTOR signaling in human lung cancer cells
Keywords: (19Z)-Halichondramide; A549 human lung cancer cells; G2/M cell cycle; GADD45; mTOR; AMPK;
TRAIL/MEKK4/p38/HSP27/Akt survival network is biphasically modulated by the Src/CIN85/c-Cbl complex
Keywords: TRAIL; tumor necrosis factor-related apoptosis-inducing ligand; CIN85; c-Cbl interacting protein of 85Â kDa; DR4/5; death receptor 4/5; TRAF4; TNF receptor-associated factor 4; GADD45; growth arrest and DNA damage induced gene-45; HSP27; heat shock protei
p38 mitogen-activated protein kinase (p38 MAPK)-mediated autoimmunity: Lessons to learn from ANCA vasculitis and pemphigus vulgaris
Keywords: AIH; autoimmune hepatitis; ANCA; anti-neutrophil cytoplasmic antibody; DSG; desmoglein; DUSP; dual specificity phosphatase; EAE; experimental autoimmune encephalomyelitis; GADD45; growth arrest and DNA damage inducible gene 45; GC; germinal center; HSP; h
IL-2 and GM-CSF are regulated by DNA demethylation during activation of T cells, B cells and macrophages
Keywords: MeDIP; immunoprecipitation of methylated DNA; DNMT; DNA methyltransferase; AID; activation-induced deaminase; APOBEC; apolipoprotein B-editing catalytic; Gadd45; growth arrest and DNA-damage-inducible 45; Tet; ten-eleven-translocation proteins; DNA demeth
Gadd45a, Gadd45b and Gadd45g expression during mouse embryonic development
Keywords: Gadd45; Expression pattern; Mouse embryogenesis; Limb buds; Neurogenesis; Somitogenesis
Damage-specific DNA binding protein 1 (DDB1) is involved in ubiquitin-mediated proteolysis of p27Kip1 in response to UV irradiation
Keywords: Damage-specific DNA binding protein 1; UV irradiation; DNA damage; CDK inhibitor p27Kip1; E3-ubiquitin-ligase; DDB1/DDB2; damage-specific DNA binding protein 1/2; Skp2; S-phase kinase-associated protein 2; CUL4A; cullin 4A; CDK; cyclin-dependent kinase; G
Epigenetic gene regulation in the adult mammalian brain: Multiple roles in memory formation
Keywords: bdnf; NF-kappaB; DNA methylation; Histone methylation; Hippocampus; Amygdala; DNMT; Gadd45
Early differential cell death and survival mechanisms initiate and contribute to the development of OPIDN: A study of molecular, cellular, and anatomical parameters
Keywords: Organophosphate-induced delayed neurotoxicity; OPIDN; BCL2; GADD45; Neurodegeneration; Diisopropylphosphorofluoridate (DFP); Anticholinergics; Central nervous system (CNS); Peripheral nervous system (PNS); Apoptotis; Necrosis
Arsenic-induced oxidative stress and its reversibility
Keywords: GSH; glutathione; GSSG; glutathione disulfide; NAC; N-acetylcysteine; ROS; reactive oxygen species; RNS; reactive nitrogen species; O2â¢â; superoxide anion; â¢OH; hydroxyl radical; 1O2; singlet oxygen; MMAV; monomethyl arsonate; MMAIII; monomethyl ars
Implication of mitogen-activated protein kinase in the induction of G1 cell cycle arrest and gadd45 expression by the carotenoid fucoxanthin in human cancer cells
Keywords: Carotenoid; Fucoxanthin; GADD45; MAPK; G1 arrest
Cancer cell iron metabolism and the development of potent iron chelators as anti-tumour agents
Keywords: 311; 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone; BpT; 2-benzoylpyridine thiosemicarbazone; CDK; cyclin-dependent kinase; CDKi; cyclin-dependent kinase inhibitor; DFO; desferrioxamine; DMT1; divalent metal ion transporter 1; DpT; di-2-pyridylketo
Upregulation and function of GADD45γ in unilateral ureteral obstruction
Keywords: tubule; GADD45; ureter obstruction; kidney; chemokine
Role of gadd45 in myeloid cells in response to hematopoietic stress
Keywords: Gadd45; Myelopoiesis; Stress response
Expression domains suggest cell-cycle independent roles of growth-arrest molecules in the adult brain of the medaka, Oryzias latipes
Keywords: Cb; cerebellum; CbSg; stratum granulare of the Cb; CbSm; stratum molecular of the Cb; CbSp; stratum ganglionare of the Cb; D; dorsal telencephalon; Dlp; area lateroposterior of D; Dm; area medialis of D; fvi; fovea isthmi; GL; glomerular layer of olfactor
Protective effect of dextromethorphan against endotoxic shock in mice
Keywords: DM; dextromethorphan; LPS; lipopolysaccharide; GalN; d-galactosomine; ALT; alanine aminotransferas; TNF-α; tumor necrosis factor-alpha; ROS; reactive oxygen species; SOD; superoxide dismutase; MIP-2; macrophage inflammatory protein-2; TSP-1; thrombospond
Sirtuins (histone deacetylases III) in the cellular response to DNA damage-Facts and hypotheses
Keywords: CBP; CREB-binding protein; DNA-PK; DNA-dependent protein kinase; DSB; DNA double strand break; FOXO; forkhead box class O; Gadd45; growth arrest and DNA damage response gene; HAT; histone acetyltransferase; HDAC; histone deacetylase; Mn-SOD; manganese sup
Receptor-independent actions of PPAR thiazolidinedione agonists: Is mitochondrial function the key?
Keywords: AICAR; AMPK activator 5-aminoimidazole-4-carboxamide riboside; AMPK; adenosine 5â²-monophosphate-activated protein kinase; AP1; activator protein 1; AUC; area under the curve; CBP; CREB-binding protein; CNS; central nervous system; COX; cyclooxygenase; C
Gene expression profiling of NRF2-mediated protection against oxidative injury
Keywords: Microarray; Lung; Hyperoxia; Transcription factor; Antioxidant; Free radicals; ANOVA; analysis of variance; AOX; aldehyde oxidase; ARE; antioxidant response element; CP; 1-Cys peroxiredoxin; DAB; 3,3â²-diaminobenzidine tetrahydrochloride; EpRE; electroph