Keywords: GLP-1، peptide-1 like glucagon; BMI, body mass index; FPG, fasting plasma glucose; GFR, glomerular filtration rate; GLP-1, glucagon-like peptide-1; HbA1c, hemoglobin A1c; HOMA-IR, homeostatic model assessment-insulin resistance; Hs-CRP, high-sensitivity C-reactive protein; LDL, low dens
مقالات ISI GLP-1، peptide-1 like glucagon (ترجمه نشده)
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Keywords: GLP-1، peptide-1 like glucagon; DPP-IV, dipeptidyl peptidase-IV; GLP-1, glucagon-like peptide-1; GIP, gastric-inhibitory peptide; ACE-I, angiotensin-I-converting enzyme; RAAS, renin-angiotensin-aldosterone system; EFSA, European Food Safety Authority; BSA, bovine serum albumin; MWCO, mo
Keywords: GLP-1، peptide-1 like glucagon; Enteral nutrition; Growth factors; Intestinal adaptation; Intestinal failure; Parenteral nutrition; Short bowel syndromeEN, Enteral nutrition; GH, Growth hormone; GLP-1, Glucagon-like peptide-1; GLP-2, Glucagon-like peptide-2; HGF, Hepatocyte growth facto
Keywords: GLP-1، peptide-1 like glucagon; ACE, angiotensin I converting enzyme; BMI, body mass index; CART, cocaine and amphetamine-regulated transcript; CCK, cholecystokinin; CRP, C-reactive protein; DXA, dual-energy X-ray absorptiometry; FFM, fat-free mass; GLP-1, glucagon-like peptide-1; MCH,
Keywords: GLP-1، peptide-1 like glucagon; Slowly digestible starch; Microencapsulation; Glycemic control; ZeinENS, microencapsulated starch; ENSP, encapsulated starch containing plasticizer; GLP-1, glucagon-like peptide-1; GOPOD, glucose oxidase/peroxidase; NCS, non-encapsulated starch (or normal
Keywords: GLP-1، peptide-1 like glucagon; Insulin therapy; Resting energy expenditure; Respiratory quotient; Type 2 diabetesBMI, body mass index; GLP-1, glucagon-like peptide-1; REE, resting energy expenditure; RQ, respiratory quotient; T2D, type 2 diabetes
Keywords: GLP-1، peptide-1 like glucagon; DV, surgical denervation of portal vein; SO, sham operation; GLP-1, glucagon-like peptide-1; OGTT, oral glucose tolerance test; HOMA-IR, homeostatic model assessment; AUC, area under the curvesPortal vein; GLP-1; Insulin sensitivity; Glucose tolerance
Keywords: GLP-1، peptide-1 like glucagon; DPP-4, dipeptidyl peptidase-4; GLP-1, glucagon-like peptide-1; RT-PCR, real-time polymerase chain reaction; O2 consumption, oxygen consumption; UCP-3, uncoupling protein-3Dipeptidyl peptidase-4; Obesity; Energy expenditure; Adipocyte hypertrophy; Hepatic
Keywords: GLP-1، peptide-1 like glucagon; FFM, fat-free mass; FPG, fasting plasma glucose; FPI, fasting plasma insulin; GIP, glucose-dependent insulinotropic polypeptide; GLP-1, glucagon-like peptide-1; iAUC, incremental area under the curve; ISR, insulin secretion rate; ISR@FPG, insulin secretio
Keywords: GLP-1، peptide-1 like glucagon; NAFLD, non-alcoholic fatty liver disease; NASH, non-alcoholic steatohepatitis; DPP-4, dipeptidyl peptidase 4; GLP-1, glucagon-like peptide-1; GIP, glucose-dependent insulinotropic polypeptide; HbA1c, hemoglobin A1c; SREBP-1c, sterol regulatory element bin
Weight loss induced by very low calorie diet is associated with a more beneficial systemic inflammatory profile than by Roux-en-Y gastric bypass
Keywords: GLP-1، peptide-1 like glucagon; BMI, body mass index; CD, cluster of differentiation; CRP, C-reactive protein; FSC, forward scatter; GLP-1, glucagon-like peptide-1; HbA1c, hemoglobin A1c; HOMA, homeostasis model assessment; IFN-γ, interferon gamma; IL, interleukin; NK cells, natural kil
Dipeptidyl peptidase-4 inhibitor, linagliptin, ameliorates endothelial dysfunction and atherogenesis in normoglycemic apolipoprotein-E deficient mice
Keywords: GLP-1، peptide-1 like glucagon; DPP-4, dipeptidyl peptidase-4; Lina, linagliptin; ApoE−/−, apolipoprotein-E deficient; GLP-1, glucagon-like peptide-1; Ex-4, exendin-4; PA, palmitic acid; WTD, western-type diet; CMC, carboxymethyl cellulose; 8-OHdG, 8-hydroxy-2′-deoxyguanosine; MCP-1, mo
A new GLP-1 analogue with prolonged glucose-lowering activity in vivo via backbone-based modification at the N-terminus
Keywords: GLP-1، peptide-1 like glucagon; GLP-1, glucagon-like peptide-1; DPP-IV, dipeptidyl peptidase IV; NEP, neutral endopeptidase; His, histidine; Thr, threonine; Val, valine; GLP-1R, GLP-1 receptor; Ala, alanine; Aha, 6-amino-hexanoic acid; DCM, dichloromethane; DMF, dimethylformamide; EA, e
Short-term administration of the GLP-1 analog liraglutide decreases circulating leptin and increases GIP levels and these changes are associated with alterations in CNS responses to food cues: A randomized, placebo-controlled, crossover study
Keywords: GLP-1، peptide-1 like glucagon; DM, type 2 diabetes; GLP-1, glucagon-like peptide-1; fMRI, functional magnetic resonance imaging; CNS, central nervous system; DLPFC, dorsolateral prefrontal cortex; pre-SMA, pre-supplementary motor area; BMI, body mass index; BIDMC, Beth Israel Deaconess
Selective novel inverse agonists for human GPR43 augment GLP-1 secretion
Keywords: GLP-1، peptide-1 like glucagon; SCFA, short chain fatty acid; SAR, structure-activity relationship; GPCR, G-protein coupled receptor; hGPR43, human GPR43; mGPR43, mouse GPR43; NF-κB, nuclear factor kappa B; GLP-1, glucagon-like peptide-1; HTS, high throughput screening; DMSO, dimethyl s
Modification of a traditional breakfast leads to increased satiety along with attenuated plasma increments of glucose, C-peptide, insulin, and glucose-dependent insulinotropic polypeptide in humans
Keywords: GLP-1، peptide-1 like glucagon; Adipokines; Blood glucose; Diet; Gastrointestinal hormones; Humans; SatietyAUC, area under the curve; BMI, body mass index; GIP, glucose-dependent insulinotropic polypeptide; GLP-1, glucagon-like peptide-1; PAI-1, plasminogen activator inhibitor-1; VAS, v
Brain GLP-1 and insulin sensitivity
Keywords: GLP-1، peptide-1 like glucagon; GLP-1; Glucagon-like peptide-1; GLP-1R; Glucose; Brain; Insulin sensitivityARC, arcuate nucleus; AP, area postrema; CRH, corticotropin-releasing hormone; GLP-1, glucagon-like peptide-1; GLP-1R, GLP-1 receptor; GTT, glucose tolerance test; NS, nucleus of t
Integrative function of adrenaline receptors for glucagon-like peptide-1 exocytosis in enteroendocrine L cell line GLUTag
Keywords: GLP-1، peptide-1 like glucagon; Adrenaline; Adrenergic receptors; Enteroendocrine L cell; Exocytosis; Glucagon-like peptide-1ARs, adrenergic receptors; FFAR1, free fatty acid receptor 1; GLP-1, glucagon-like peptide-1; IP3, inositol triphosphate; PYY, peptide YY; tPA, tissue-type plasmi
Comparison of the susceptibility of porcine and human dipeptidyl-peptidase IV to inhibition by protein-derived peptides
Keywords: GLP-1، peptide-1 like glucagon; α-la, alpha-lactalbumin; GIP, glucose-dependent insulinotropic polypeptide; β-lg, beta-lactoglobulin; GLP-1, glucagon-like peptide-1; Gly-Pro-p-NA, Gly-Pro-para-nitroanilide; Ki, inhibition constant; Lf, lactoferrin; NPY, neuropeptide Y; pDPP-IV, porcine
Ghrelin regulates GLP-1 production through mTOR signaling in L cells
Keywords: GLP-1، peptide-1 like glucagon; Enteroendocrine L cells; Ghrelin; GHSR1a; GLP-1; Incretin; mTORC1D-Lys-3-GHRP-6, D-Lys-3-GH-releasing peptide-6; GCG, Proglucagon; GLP-1, Glucagon-like peptide-1; mTOR, mechanistic target of rapamycin; Raptor, regulatory-associated protein of mTOR; S6, ri
Gemigliptin, a dipeptidyl peptidase-4 inhibitor, inhibits retinal pericyte injury in db/db mice and retinal neovascularization in mice with ischemic retinopathy
Keywords: GLP-1، peptide-1 like glucagon; ROS, reactive oxygen species; DPP-4, dipeptidyl peptidase-4; GLP-1, glucagon-like peptide-1; VEGF, vascular endothelial growth factor; ICAM-1, intercellular adhesion molecule-1; PAI-1, plasminogen activator inhibitor-1; PEDF, pigment epithelium-derived fa
Dipeptidyl peptidase-4 (DPP-4): Localization and activity in human and rodent islets
Keywords: GLP-1، peptide-1 like glucagon; DPP-4, dipeptidyl peptidase 4; GLP-1, glucagon-like peptide-1; GIP, glucose dependent insulinotropic polypeptide; DIRKO, double incretin receptor knockout; SDF-1, stromal cell-derived factor-1Dipeptidyl peptidase 4; Incretin; Islet of Langerhans; Type 2 d
Calcium/calmodulin-dependent serine protein kinase is involved in exendin-4-induced insulin secretion in INS-1 cells
Keywords: GLP-1، peptide-1 like glucagon; cAMP, cyclic adenosine monophosphate; CASK, calcium/calmodulin-dependent serine protein kinase; Epac2, exchange protein directly activated by cAMP-2; ESCA-AM, 8-pCPT-2′-O-Me-cAMP-AM; Ex-4, exendin-4; GLP-1, glucagon-like peptide-1; GSIS, glucose-stimulate
Four-week coffee consumption affects energy intake, satiety regulation, body fat, and protects DNA integrity
Keywords: GLP-1، peptide-1 like glucagon; BIA, bioelectrical impedance analysis; BMI, body-mass index; 5-CQA, 5-caffeoylquinic acid; FFM, fat free mass; FM, fat mass; GIP, glucose-dependent insulinotropic polypeptide; GLP-1, glucagon-like peptide-1; 5-HT, 5-hydroxytryptamine (serotonin); MB, mark
Role of anorectic N-acylethanolamines in intestinal physiology and satiety control with respect to dietary fat
Keywords: GLP-1، peptide-1 like glucagon; AEA, anandamide; 2-AG, 2-arachidonoyl glycerol; CCK, cholescystokinin; EPEA, eicosapentaenoylethanolamide; DHEA, docosahexaenoylethanolamide; FAAH, fatty acid amide hydrolase; GLP-1, glucagon-like peptide-1; LEA, linoleoylethanolamide; NAAA, N-acylethanol
Early liraglutide treatment is better in glucose control, β-cell function improvement and mass preservation in db/db mice
Keywords: GLP-1، peptide-1 like glucagon; GLP-1, glucagon-like peptide-1; T2DM, type 2 diabetes mellitus; DPPIV, dipeptidyl peptidase IV; AIRg, acute insulin response to glucose; BCM, β-cell mass; ACM, α-cell mass; UPKSD, the United Kingdom Prospective Diabetes Study; FBG, fasting blood glucose;
Liraglutide enhances glucose transporter 4 translocation via regulation of AMP-activated protein kinase signaling pathways in mouse skeletal muscle cells
Keywords: GLP-1، peptide-1 like glucagon; AMPK, AMP-activated protein kinase; ACC, acetyl-CoA carboxylase; cAMP, cyclic adenosine monophosphate; GLP-1, glucagon-like peptide-1; GLUT4, glucose transporter 4; CC, compound C.Glucagon-like peptide 1; AMP-activated protein kinase; Glucose transporter
Isolation and characterization of peptides with dipeptidyl peptidase-IV inhibitory activity from pepsin-treated bovine whey proteins
Keywords: GLP-1، peptide-1 like glucagon; α-la, α-lactalbumin; DPP-IV, dipeptidyl peptidase-IV; FPLC, fast protein liquid chromatography; GIP, glucose-dependent insulinotropic polypeptide; GLP-1, glucagon-like peptide-1; Gly-Pro-p-NA, Gly-Pro-para-nitroanilide; IC50, concentration causing 50% inh
Effects of Roux-en-Y gastric bypass on energy and glucose homeostasis are preserved in two mouse models of functional glucagon-like peptide-1 deficiency ab
Keywords: GLP-1، peptide-1 like glucagon; α-Gust−/−, α-gustducin deficient mice; GLP-1, glucagon-like peptide-1; GLP-1R, glucagon-like peptide-1 receptor; Glp1r−/−, glucagon-like peptide-1 receptor deficient mice; HOMA-IR, Homeostasis Model Assessment-Insulin Resistance; PF-sham, pair-fed sham; R
Dipeptidyl peptidase-4 inhibition by Pterocarpus marsupium and Eugenia jambolana ameliorates streptozotocin induced Alzheimer's disease
Keywords: GLP-1، peptide-1 like glucagon; T2D, type 2 diabetes; AD, Alzheimer's disease; DPP-4, dipeptidyl peptidase-4; GLP-1, glucagon-like peptide-1; GSK-3, glycogen synthase kinase-3; STZ, streptozotocin; Aβ, amyloid beta; p-tau, phosphorylated tau; RAM, radial arm maze; HB, hole-board; TNF-α,
GLP-1 receptor agonism ameliorates hepatic VLDL overproduction and de novo lipogenesis in insulin resistance
Keywords: GLP-1، peptide-1 like glucagon; Glucagon-like peptide-1 (GLP-1); Very low density lipoprotein (VLDL); Fasting dyslipidemia; Insulin resistance; Hepatic steatosis; IncretinapoB100, apolipoproteinB100; FFA, free fatty acid; GLP-1, glucagon-like peptide-1; GLP-1R, GLP-1 receptor; ICV, intr
Design, synthesis and biological evaluation of hetero-aromatic moieties substituted pyrrole-2-carbonitrile derivatives as dipeptidyl peptidase IV inhibitors
Keywords: GLP-1، peptide-1 like glucagon; DPP4 inhibitors; Selectivity; Reversible kinetic characterization; Oral bioavailability; Oral glucose tolerance testDPP4, dipeptidyl peptidase IV; GLP-1, glucagon-like peptide-1; T2DM, type 2 diabetes mellitus; SARs, structure–activity relationships; OGTT
Glucagon-like peptide-1 production in the GLUTag cell line is impaired by free fatty acids via endoplasmic reticulum stress
Keywords: GLP-1، peptide-1 like glucagon; GLP-1, glucagon-like peptide-1; PC1/3, prohormone convertase 1/3; FFAs, free fatty acids; ER stress, endoplasmic reticulum stress; XBP1, X-box binding protein 1; CHOP, C/EBP homologous proteinER stress; GLP-1; PC1/3; GLUTag
Design, synthesis and biological evaluation of 4-fluoropyrrolidine-2-carbonitrile and octahydrocyclopenta[b]pyrrole-2-carbonitrile derivatives as dipeptidyl peptidase IV inhibitors
Keywords: GLP-1، peptide-1 like glucagon; DPP4 inhibitors; GLP-1; Selectivity; Oral bioavailability; Oral glucose tolerance tests; hERGDPP4, dipeptidyl peptidase IV; GLP-1, glucagon-like peptide-1; FAP, fibroblast activation protein; T2DM, type 2 diabetes mellitus; SARs, structure–activity relati
Serum levels of advanced glycation end products (AGEs) are independently correlated with circulating levels of dipeptidyl peptidase-4 (DPP-4) in humans
Keywords: GLP-1، peptide-1 like glucagon; DPP-4, dipeptidyl peptidase-4; GLP-1, glucagon-like peptide-1; GIP, glucose-dependent insulinotropic polypeptides; AGEs, advanced glycation end products; receptor for AGEs, RAGE; BP, blood pressure; hsCRP, high-sensitivity C-reactive protein; ELISA, enzym
A dipeptidyl peptidase-4 inhibitor, sitagliptin, exerts anti-inflammatory effects in type 2 diabetic patients
Keywords: GLP-1، peptide-1 like glucagon; DPP-4, dipeptidyl peptidase-4; GLP-1, glucagon-like peptide-1; HOMA-IR, homeostasis model assessment of insulin resistance; BMI, body mass index; LDL-C, low-density lipoprotein cholesterol; CRP, C-reactive protein; IL-6, interleukin-6; IL-10, interleukin-
Reduction in cardiovascular risk factors and insulin dose, but no beta-cell regeneration 1 year after Roux-en-Y gastric bypass in an obese patient with type 1 diabetes: A case report
Keywords: GLP-1، peptide-1 like glucagon; BMI, Body mass index; GIP, Glucose-dependent insulinotropic polypeptide; GLP-1, Glucagon-like peptide-1; HbA1c, Glycosylated hemoglobin; HDL, High-density lipoprotein; HOMA-IR, Homeostasis model assessment of insulin resistance; LDL, Low-density lipoprote
Curcumin stimulates glucagon-like peptide-1 secretion in GLUTag cells via Ca2+/calmodulin-dependent kinase II activation
Keywords: GLP-1، peptide-1 like glucagon; 2-APB, 2-aminoethyl diphenylborinate; BMC, bisdemethoxycurcumin; CaMKII, Ca2+/calmodulin-dependent kinaseII; DMC, demethoxycurcumin; DPP-4, dipeptidyl peptidase IV; ERK, extracellular signal-regulated kinase; Fos, forskolin; GLP-1, glucagon-like peptide-1
Effects of oleic acid and olive oil on gastric emptying, gut hormone secretion and appetite in lean and overweight or obese males
Keywords: GLP-1، peptide-1 like glucagon; Free fatty acids; Triglycerides; Cholecystokinin; Peptide-YY; Glucagon-like peptide-1; Gastric emptyingCCK, cholecystokinin; FFA, free fatty acid; GE, gastric emptying; GLP-1, glucagon-like peptide-1; PYY, peptide-YY; TG, triacylglyceride
Effect of low- and high-glycemic load on circulating incretins in a randomized clinical trial
Keywords: GLP-1، peptide-1 like glucagon; GI, glycemic index; GL, glycemic load; GIP, glucose-dependent insulinotropic polypeptide; GLP-1, glucagon-like peptide-1; BMI, body mass index; CARB, Carbohydrates and Related Biomarkers Study; FHCRC, Fred Hutchinson Cancer Research Center; HNL, Human Nut
The alpha-glucosidase inhibitor miglitol affects bile acid metabolism and ameliorates obesity and insulin resistance in diabetic mice
Keywords: GLP-1، peptide-1 like glucagon; α-GI, Alpha-glucosidase inhibitors; D2, type 2 iodothyronine deiodinase; FXR, farnesoid X receptor; G-6-Pase, glucose 6-phosphatase; GLP-1, glucagon-like peptide-1; MCP-1, monocyte chemotactic protein-1; PAI-1, plasminogen activator inhibitor-1; TNF-α, tu
The combination of GIP plus xenin-25 indirectly increases pancreatic polypeptide release in humans with and without type 2 diabetes mellitus
Keywords: GLP-1، peptide-1 like glucagon; Alb, albumin alone; GLP-1, glucagon-like peptide-1; GIP, glucose-dependent insulinotropic polypeptide; G + X, GIP plus Xen; IGT, impaired glucose tolerance; ISR, insulin secretion rate; ivGGIs, intravenous graded glucose infusions; NTSR1, neurotensin rece
Roles for corticotropin-releasing factor receptor type 1 in energy homeostasis in mice
Keywords: GLP-1، peptide-1 like glucagon; CRF, corticotrophin-releasing factor; CRFR, CRF receptor; Ucn, urocortin; GTT, glucose tolerance test: ITT, insulin tolerance test; HPA, hypothalamus–pituitary–adrenal; GSIS, glucose stimulated insulin secretion; GLP-1, glucagon-like peptide-1; GIP, gluco
Saxagliptin: A dipeptidyl peptidase-4 inhibitor ameliorates streptozotocin induced Alzheimer's disease
Keywords: GLP-1، peptide-1 like glucagon; Glucagon-like peptide-1; Type 2 diabetes; Amyloid beta; Tau; Inflammatory markers; Hippocampus; Wistar ratsT2D, type 2 diabetes; AD, Alzheimer's disease; DPP-4, dipeptidyl peptidase-4; GLP-1, glucagon-like peptide-1; GSK-3, glycogen synthase kinase-3; STZ
Exendin (5-39), an antagonist of GLP-1 receptor, modulates synaptic transmission via glutamate uptake in the dentate gyrus
Keywords: GLP-1، peptide-1 like glucagon; ACSF, artificial cerebrospinal fluid; ANOVA, analysis of variance; DG, dentate gyrus; DHK, dihydrokainic acid; EAAT, excitatory amino acid transporter; Ex, exendin (5-39); fEPSP, field excitatory postsynaptic potentials; GLP-1, glucagon-like peptide-1; i.
The role of clusterin on pancreatic beta cell regeneration after exendin-4 treatment in neonatal streptozotocin administrated rats
Keywords: GLP-1، peptide-1 like glucagon; β cell, beta cell; Ex4, exendin-4; GLP-1, glucagon-like peptide-1; nSTZ, neonatal streptozotocin; nCLU, nuclear-clusterin; Pdx-1, pancreatic duodenal homebox-1; PBS, phosphate-buffered-saline; SSC, saline-sodium citrate; sCLU, secreted-clusterin; STZ, str
The ductal origin of structural and functional heterogeneity between pancreatic islets
Keywords: GLP-1، peptide-1 like glucagon; CK, cytokeratin; E-cadherin, epithelial-cadherin; ed, embryonic day; EP-CAM, epithelial cell adhesion molecule; ew, embryonic week; GCG, glucagon; GHRL, ghrelin; GLP-1, glucagon-like peptide-1; HE, haematoxylin and eosin; HNF1β, hepatocyte nuclear factor
Molecular mechanisms of lipoapoptosis and metformin protection in GLP-1 secreting cells
Keywords: GLP-1، peptide-1 like glucagon; AMPK, AMP-activated protein kinase; JNK2, c-Jun N-terminal kinase; GLP-1, glucagon-like peptide-1; ROS, reactive oxygen species; MAPKK, mitogen-activated protein kinase kinaseGlucagon-like peptide-1; Metformin; Lipotoxicity; L-cell
Possible involvement of melanocortin-4-receptor and AMP-activated protein kinase in the interaction of glucagon-like peptide-1 and leptin on feeding in rats
Keywords: GLP-1، peptide-1 like glucagon; AGRP, agouti-related protein; AMPK, AMP-activated protein kinase; α-MSH, α-melanocyte-stimulating hormone; CART, cocaine-and amphetamine-regulated transcript; CCK, cholecystokinin; CNS, central nervous system; GLP-1, glucagon-like peptide-1; GAPDH, glycer
Neural responsivity to food cues in fasted and fed states pre and post gastric bypass surgery
Keywords: GLP-1، peptide-1 like glucagon; dlPFC, dorsolateral prefrontal cortex; RYGB, Roux-en-Y gastric bypass; PYY3–36, peptide YY3–36; GLP-1, glucagon-like peptide-1; BMI, body mass indexRYGB; Roux; Obese; fMRI; Bariatric