Keywords: HHCy، hyperhomocysteinemia; CBS, cystathionine beta synthase; GSH, glutathione; Hcy, homocysteine; HHcy, hyperhomocysteinemia; HO-1, heme oxygenase I; PON1, paraoxonase 1; NQO1, NAD(P)H:quinone oxidoreductase; XME, xenobiotic-metabolizing enzymeHyperhomocysteinemia; Mice; Liver; Cad
مقالات ISI HHCy، hyperhomocysteinemia (ترجمه نشده)
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Keywords: HHCy، hyperhomocysteinemia; BMC, bone mineral content; BS, bone surface; BV, bone volume; CF, control-fed; Conn.Dn., connectivity density; CTX-1, C-terminal telopeptide of type 1 collagen; FGF21, fibroblast growth factor-21; HFD, high-fat diet; HHCy, hyperhomocysteinemia; IDI, inden
miR-125b targets DNMT3b and mediates p53 DNA methylation involving in the vascular smooth muscle cells proliferation induced by homocysteine
Keywords: HHCy، hyperhomocysteinemia; VSMCs, Vascular Smooth Muscle Cells; AS, atherosclerosis; Hcy, homocysteine; HHcy, Hyperhomocysteinemia; DNMT3b, DNA (cytosine-5)-methyltransferase 3b; nMS-PCR, nested methylation-specific-PCR; UTR, untranslated region; miRNAs, microRNAs; mfe, minimum fre
Corrective effects of hepatotoxicity by hepatic Dyrk1a gene delivery in mice with intermediate hyperhomocysteinemia
Keywords: HHCy، hyperhomocysteinemia; ALT, alanine aminotransferase; APO, apolipoprotein; CBS, cystathionine beta synthase; DCPIP, 2,6-dichlorophenolindophenol; hcy, homocysteine; HDLs, high-density lipoproteins; hhcy, hyperhomocysteinemia; HPLC, high-performance liquid chromatography; KYNA,
Methyl donor deficiency in H9c2 cardiomyoblasts induces ER stress as an important part of the proteome response
Keywords: HHCy، hyperhomocysteinemia; CHAPS, 3-(3-cholamidopropyl)dimethylammonio)-1-propanesulfonic acid; C, control; 2-D, two-dimension; DTT, dithiothreitol; ER, endoplasmic reticulum; FBS, fetal bovine serum; FC, fold change; FD, folate-deficient; HHcy, hyperhomocysteinemia; Hcy, homocyste
Homocysteine and DNA methylation: A review of animal and human literature
Keywords: HHCy، hyperhomocysteinemia; Hcy, homocysteine; HHcy, hyperhomocysteinemia; HH, hyperhomocysteinemic; SAM, S-adenosylmethionine; SAH, S-adenosylhomocysteine; HM, high methionine; MD, methionine deficient; LF, low folate; LB6, low vitamin B6; LB12, low vitamin B12; FD, folate deficien
Homocysteine modifies extracellular ATP availability in macrophages
Keywords: HHCy، hyperhomocysteinemia; Hcy, homocysteine; HHcy, hyperhomocysteinemia; CAD, coronary artery disease; FBS, fetal bovine serum; NTPDase, ectonucleoside triphosphate diphosphohydrolases; ADO, adenosineHomocysteine; Macrophages; Ecto-5′-nucleotidase; NTPDase
Homocysteine activates vascular smooth muscle cells by DNA demethylation of platelet-derived growth factor in endothelial cells
Keywords: HHCy، hyperhomocysteinemia; Hcy, Homocysteine; HHcy, Hyperhomocysteinemia; HUVECs, Human umbilical vein endothelial cells; 5-aza-CdR, 5-aza-2′ deoxycytidine; 3-DZA, 3-deazadenosine; MSP, Methylation-specific PCR; ECs, Endothelial cells; PDGFs, Platelet-derived growth factors; VSMCs,
Ginsenoside Rb1 prevents homocysteine-induced endothelial dysfunction via PI3K/Akt activation and PKC inhibition
Keywords: HHCy، hyperhomocysteinemia; Akt, protein kinase B; ECGS, endothelial cell growth supplement; eNOS, endothelial nitric oxide synthase; FBS, fetal bovine serum; GS, ginsenosides; Hcy, homocysteine; HHcy, Hyperhomocysteinemia; HUVECs, human umbilical vein endothelial cells; l-NAME, N-n
Simultaneous quantification of S-adenosyl methionine and S-adenosyl homocysteine in human plasma by stable-isotope dilution ultra performance liquid chromatography tandem mass spectrometry
Keywords: HHCy، hyperhomocysteinemia; HC, high control; HHCY, hyperhomocysteinemia; HPLC, high-performance liquid chromatography; LC, low control; LC–MS/MS, liquid chromatography with tandem mass spectrometry; MAT, methionine adenosyltransferase; MRM, multiple reaction monitoring; MS/MS, tand
Serum folate is a reliable indicator of hyperhomocysteinemia and borderline hyperhomocysteinemia in young adults
Keywords: HHCy، hyperhomocysteinemia; AUC, area under the receiver operating characteristic curve; BHcy, borderline hyperhomocysteinemia; BMI, body mass index; CI, confidence intervals; HHcy, hyperhomocysteinemia; LDL, low-density lipoprotein; NHcy, normohomocysteinemia; OR, odds ratio; PLP,
Hyperhomocysteinemia is associated with hypertriglyceridemia in mice with methylenetetrahydrofolate reductase deficiency
Keywords: HHCy، hyperhomocysteinemia; MTHFR, methylenetetrahydrofolate reductase; Hcy, homocysteine; HHcy, hyperhomocysteinemia; ApoE, apolipoprotein E; ApoA-I, apolipoprotein A-I; ApoA-IV, apolipoprotein A-IV; CD, control diet; FD, folate-deficient diet
Hyperhomocysteinemia induced by feeding rats diets rich in dl-homocysteine thiolactone promotes alterations on carotid reactivity independent of arterial structure
Keywords: HHCy، hyperhomocysteinemia; HHcy, hyperhomocysteinemia; NO, nitric oxide; ET-1, endothelin-1; PHE, phenylephrine; ACh, acetylcholineHyperhomocysteinemia; Rat carotid artery; Media layer; Vascular responsiveness; Endothelin-1; Phenylephrine; Acetylcholine
Homocysteine and lipids: S-Adenosyl methionine as a key intermediate
Keywords: HHCy، hyperhomocysteinemia; Hcy, homocysteine; HHCY, hyperhomocysteinemia; SAM, S-adenosyl methionine; SAH, S-adenosylhomocysteine; PC, phosphatidylcholine; PE, phosphatidylethanolamine; PEMT, phosphatidyl ethanolamine methyltransferase; LCAT, lecithin-cholesterol acyltransferase; M
Association of homocysteinemia with high concentrations of serum insulin and uric acid in Brazilian subjects with metabolic syndrome genotyped for C677T polymorphism in the methylenetetrahydrofolate reductase gene
Keywords: HHCy، hyperhomocysteinemia; Metabolic syndrome; Insulin resistance; Hyperhomocysteinemia; C677T polymorphism in the MTHFR gene; Cardiovascular disease; HumanBMI, body mass index; HDL-C, high-density lipoprotein cholesterol; Hhcy, hyperhomocysteinemia; HOMA-IR, homeostatic model asse
Ubiquinol-10/lipids ratios in consecutive patients with different angiographic findings
Keywords: HHCy، hyperhomocysteinemia; BHT, butylated hydroxytoluene; CAD, coronary artery disease; CoQ10, coenzyme Q10; γ-GT, γ-glutamyltransferase; HDL-C, high-density lipoprotein cholesterol; HHCY, hyperhomocysteinemia; HLP, hyperlipidaemia; HMG-CoA, 3-hydroxy-3-methyl-glutaryl-coenzyme A;
Polymorphism C776G in the transcobalamin II gene and homocysteine, folate and vitamin B12 concentrations. Association with MTHFR C677T and A1298C and MTRR A66G polymorphisms in healthy children
Keywords: HHCy، hyperhomocysteinemia; TC II, transcobalamin II; HHcy, hyperhomocysteinemia; Hcy, homocysteine; MTHFR, methylenetetrahydrofolate reductase; MTRR, methionine synthase reductase; TC-R, transcobalamin-receptorHomocysteine; Transcobalamin II; Children; Methionine synthase reductase
Homocysteine Modulates the CD40/CD40L System
Keywords: HHCy، hyperhomocysteinemia; BSA, bovine serum albumin; CD40L, CD40 ligand; EDTA, ethylenediaminetetraacetic acid; Hcy, homocysteine; HEPES, N-2 hydroxyethyl piperazine-N 1-2-ethanesulfonic acid; HHcy, hyperhomocysteinemia; HUVECs, human umbilical vein endothelial cells; Ig, immunogl
ER chaperones in mammalian development and human diseases
Keywords: HHCy، hyperhomocysteinemia; ER, endoplasmic reticulum; ERAD, ER-associated degradation; HHcy, hyperhomocysteinemia; PDI, protein disulfide isomerase; PrPsc, scrapie-associated PrP; STEC, Shiga toxigenic Escherichia coli; SubAB, AB5 subtilase cytotoxin; UPR, unfolded protein response
Mechanisms of homocysteine neurotoxicity in neurodegenerative diseases with special reference to dementia
Keywords: HHCy، hyperhomocysteinemia; Hcy, homocysteine; HHCY, hyperhomocysteinemia; AD, Alzheimer disease; Aβ, amyloid beta; SAH, S-adenosyl homocysteine; SAM, S-adenosyl methionineHomocysteine; Brain; Folate; Vitamin B12; Dementia; Oxidative stress
Role of redox factor-1 in hyperhomocysteinemia-accelerated atherosclerosis
Keywords: HHCy، hyperhomocysteinemia; HHcy, hyperhomocysteinemia; Hcy, homocysteine; MCP-1, monocyte chemoattractant protein-1; Ref-1, redox factor-1; IL-8, interleukin-8; ROS, reactive oxygen species; NF-κB, nuclear factor-κB; PMA, phorbol 12-myristate 13-acetate; DPI, diphenyleneiodonium; T