Keywords: CCK; cholecystokinin; CNS; central nervous system; EEC; enteroendocrine cell; FFAR; free fatty acid receptor; GABA; gamma-aminobutyric acid; GI; gastrointestinal; GLP; glucagon-like peptide; IB4; isolectin B4; IBD; inflammatory bowel disease; LPS; lipopol
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Keywords: Microbiota; Microglia; Vagal afferents; Food intake; BDNF; brain-derived neurotrophic factor; CCK; cholecystokinin; CNS; central nervous system; GDNF; glia-derived neurotrophic factor; GF; germ-free; GI; gastrointestinal; HF; high fat; IRS1; Insulin recep
Keywords: Choroidal neovascularization; Fibrosis; Macrophage polarization; Doxycycline; FA; fluorescein angiography; IB4; isolectin B4; EMT; epithelial-mesenchymal transition; pSTAT6; phosphorylated STAT6; LCNV; laser-induced choroidal neovascularization; AMD; age-
Keywords: CGRP; calcitonin gene-related peptide; DRG; dorsal root ganglion; GDNF; glial cell line-derived neurotrophic factor; IB4; isolectin B4; NGF; nerve growth factor; P2X3; purinogenic 2X3; PGP9.5; protein gene product 9.5; PO; postoperation; TNF-a; tumor necr
Keywords: ACSF; artificial cerebrospinal fluid; ATP; adenosine-5â²-triphosphate; BoNT/A; botulinum toxin-type A; Cm; membrane capacitance; DRG; dorsal root ganglia; ES; electrical stimulation; FM4-64; N-(3-triethylammoniumpropyl)-4-(6-(4-(diethylamino)phenyl)) exa
Keywords: ATF-3; activating transcription factor-3; cDNA; complementary DNA; CGRP; calcitonin gene-related peptide; CNS; central nervous system; cRNA; complementary RNA; DIG; digoxigenin; DIV; day in vitro; DRG; dorsal root ganglion; ECM; extracellular matrix; FGF2
Keywords: DRG; dorsal root ganglion; TG; trigeminal ganglion; TRP; transient receptor potential; IB4; isolectin B4; trk; tyrosine receptor kinase; LPPS; linear programming problem solver; CGRP; calcitonin gene receptor peptide; SP; substance P; Molecular profile; T
Keywords: α-sma; alpha smooth muscle actin; BSA; bovine serum albumin; cc-3; cleaved caspase-3; Cho; choroid; GFAP; glial fibrillary acidic protein; IB4; isolectin B4; Iba1; ionized calcium binding adapter molecule 1; INL; inner nuclear layer; NG2; neuron-glial an
Expression of vesicular glutamate transporters in transient receptor potential ankyrin 1 (TRPA1)-positive neurons in the rat trigeminal ganglion
Keywords: ANOVA; analysis of variance; CFA; Complete Freund's Adjuvant; CGRP; calcitonin gene-related peptide; Cy; Cyanine; DRG; dorsal root ganglion; FITC; fluorescein isothiocyanate; GFP; green fluorescent protein; IB4; Griffonia (Bandeiraea) simplicifolia lect
Resident fibroblast expansion during cardiac growth and remodeling
Keywords: GFP; green fluorescent protein; mCrem; mutated estrogen receptor P1 bacteriophage Cre recombinase; IB4; isolectin GS-IB4; EdU; 5-ethynyl-2-deoxyuridine; αSMA; alpha smooth muscle actin; ECM; extracellular matrix; MI; myocardial infarction; LAD; left ante
A Novel Role for Lymphotactin (XCL1) Signaling in the Nervous System: XCL1 Acts via its Receptor XCR1 to Increase Trigeminal Neuronal Excitability
Keywords: aCSF; artificial cerebrospinal fluid; CCI; chronic constriction injury; CGRP; calcitonin gene-related peptide; Cy3; indocarbocyanine; ERK; extracellular signal-regulated kinase; GFAP; glial fibrillary acidic protein; IB4; isolectin B4; Iba1; ionized calci
Modality-specific peripheral antinociceptive effects of μ-opioid agonists on heat and mechanical stimuli: Contribution of sigma-1 receptors
Keywords: Sigma-1 receptors; Opioid drugs; Peripheral antinociception; Mechanical stimulus; Heat stimulus; TRPV1-Expressing neurons; DRG; dorsal root ganglion; IB4; isolectin B4; i.pl.; intraplantar; KO; knockout; NeuN; neuronal nuclei; PRE-084; ([2-(4-morpholineth
Connexin36 Expression in Primary Afferent Neurons in Relation to the Axon Reflex and Modality Coding of Somatic Sensation
Keywords: CGRP; calcitonin gene-related polypeptide; CNS; central nervous system; Cx36; connexin36; eGFP; enhanced green fluorescent protein; IB4; isolectin-B4; PBS; phosphate-buffered saline; RT-PCR; reverse transcription polymerase chain reaction; SP; substance P
Nociceptor-like rat dorsal root ganglion neurons express the angiotensin-II AT2 receptor throughout development
Keywords: DRG; dorsal root ganglia; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; AT2R; angiotensin-II type 2 receptor; IB4; isolectin B4; Ret; receptor for the glial-derived growth factor; GDNF; glial-derived neurotrophic factor; trkA; tropomyosin receptor kina
Ablation of IB4 non-peptidergic afferents in the rat facet joint prevents injury-induced pain and thalamic hyperexcitability via supraspinal glutamate transporters
Keywords: GLT-1; glial glutamate transporter 1; EAAC1; excitatory amino acid carrier 1; IB4; isolectin, B4; IB4-SAP; isolectin-B4 conjugated saporin; VPL; ventral posterolateral nucleus; PAG; periaqueductal gray; ACC; anterior cingulate cortex; S1; primary somatose
Involvement of TRPV1 and TDAG8 in Pruriception Associated with Noxious Acidosis
Keywords: ASIC; acid-sensing ion channel; CP48/80; compound 40/80; DRG; dorsal root ganglion; ET; endothelin; GPCR; G-protein-coupled receptor; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; HT; hydroxytryptamine; IB4; isolectin B4; IRES; internal rib
Selective elimination of isolectin B4-binding trigeminal neurons enhanced formalin-induced nocifensive behavior in the upper lip of rats and c-Fos expression in the trigeminal subnucleus caudalis
Keywords: IB4; c-Fos; GABAA; Saporin; Formalin test;
VEGF regulates relative allocation of Isl1+ cardiac progenitors to myocardial and endocardial lineages
Keywords: VEGF; Isl1; Flk1; Multipotent cardiac progenitors; A; atrium; CPCs; cardiac progenitor cells; C-Casp3; cleaved caspase-3; GOF; gain-of function; HPF; per high power field; IB4; Isolectin B4; ISH; in situ hybridization; LOF; loss-of-function; MHC; myosin h
Research ReportVoltage-gated potassium channels involved in regulation of physiological function in MrgprA3-specific itch neurons
Keywords: SLIGRL; Ser-Leu-Ile-Gly-Arg-Leu; BAM; bovine adrenal medulla peptide; ET-1; endothelin-1; α-Me-5HT; alpha-methyl-serotonin; IB4; isolectin-B4; TEA; tetraethylammonium; Itch; MrgprA3; DRG; Kv current;
Immunostaining for Homer reveals the majority of excitatory synapses in laminae I-III of the mouse spinal dorsal horn
Keywords: CGRP; calcitonin gene-related peptide; DAB; diaminobenzidine; IB4; isolectin B4; LTMR; low-threshold mechanoreceptor; VGAT; vesicular GABA transporter; VGLUT1; vesicular glutamate transporter 1; VGLUT2; vesicular glutamate transporter 2; glutamatergic syn
Increase of transcription factor EB (TFEB) and lysosomes in rat DRG neurons and their transportation to the central nerve terminal in dorsal horn after nerve injury
Keywords: DH; dorsal horn; DRG; dorsal root ganglion; IB4; Isolectin B4; Iba1; ionized calcium binding adapter molecule 1; IHC; immunohistochemistry; Neu-1; neuramidase-1; PB; phosphate buffer; PBS; phosphate-buffered saline; PFA; paraformaldehyde; RT; room tempera
mTOR signaling controls VGLUT2 expression to maintain pain hypersensitivity after tissue injury
Keywords: ANOVA; one-way analysis of variance; CGRP; anti-calcitonin gene-related peptide; DRG; dorsal root ganglion; IB4; biotin-conjugated isolectin B4; mTOR; mammalian target of rapamycin; p-mTOR; phosphorylated mTOR; TRPV1; transient receptor potential vanilloi
The L-type voltage-gated calcium channel modulates microglial pro-inflammatory activity
Keywords: [Ca2+]i; intracellular calcium concentration; DAB; diaminobenzidine; DG; dentate gyrus; FBS; fetal bovine serum; GFAP; glial fibrillary acidic protein; IB4; isolectin B4; IFNγ; interferon-gamma; IL-1β; interleukin-1β; KW; Kruskal-Wallis; LPS; lipopol
Increased expression of HCN2 channel protein in L4 dorsal root ganglion neurons following axotomy of L5- and inflammation of L4-spinal nerves in rats
Keywords: CCI; chronic constriction injury; DAPI; 4â²,6-diamidino-2-phenylindole; DRG; dorsal root ganglion; HCN; hyperpolarization-activated cyclic nucleotide-gated (HCN) channels; HWL; paw withdrawal latency to a noxious heat stimulus; IB4; isolectin-B4; L4; lum
Inflammation-induced increase in nicotinic acetylcholine receptor current in cutaneous nociceptive DRG neurons from the adult rat
Keywords: AITC; allyl isothiocyanate; ANOVA; analysis of variance; Cap; capsaicin; CFA; complete Freund's adjuvant; DiI; 1,1â²-dioctadecyl-3,3,3â²,3â²-tetramethylindocarbocyanine perchlorate; DMSO; dimethyl sulfoxide; DRG; dorsal root ganglion; EGTA; ethylene
Central or peripheral delivery of an adenosine A1 receptor agonist improves mechanical allodynia in a mouse model of painful diabetic neuropathy
Keywords: A1R; adenosine A1 receptor; CGRP; calcitonin gene-related peptide; CPA; N6-cyclopentyladenosine; DRG; dorsal root ganglia; ECL; Enhanced Chemiluminescence reagent; hPAP; human prostatic acid phosphatase; IB4; isolectin IB4; ITU; 5â²-iodotubercidin; NT5E;
Notch4 reveals a novel mechanism regulating Notch signal transduction
Keywords: ANK; ankyrin repeat; DSL; Delta, Serrate and Lag-2; JAG1; Jagged1; DLL1; Delta-like 1; DLL4; Delta-like 4; E; embryonic day; EC; extracellular domain; EGF; epidermal growth factor; ER; endoplasmic reticulum; ES; embryonic stem; HD; heterodimerisation doma
Regulation of alternative VEGF-A mRNA splicing is a therapeutic target for analgesia
Keywords: VEGF-A; vascular endothelial growth factor-A; SRPK1; serine arginine protein kinase 1; SRSF1; serine arginine splice factor 1; VEGFR2; vascular endothelial growth factor receptor 2; IB4; isolectin B4; TRPV1; transient receptor potential vanilloid 1; CV; c
Inflammation enhances Y1 receptor signaling, neuropeptide Y-mediated inhibition of hyperalgesia, and substance P release from primary afferent neurons
Keywords: aCSF; artificial cerebrospinal fluid; ANOVA; analysis of variance; CGRP; calcitonin gene-related peptide; CFA; complete Freund's adjuvant; DRG; dorsal root ganglion; HEPES; 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid; IB4; isolectin-B4; NK1R
Expression of NPR-B in neurons of the dorsal root ganglia of the rat
Keywords: CG-B; CGRP; DRG; IB4; Immunohistochemistry; Sensory neurons;
Reduced expression of pain mediators and pain sensitivity in amyloid precursor protein over-expressing CRND8 transgenic mice
Keywords: AD; Alzheimer's disease; APP; amyloid precursor protein; Aβ; β-amyloid; CFA; complete Freud's adjuvant; CGRP; calcitonin gene-related peptide; DAB; 3,3â²-diaminobenzidine; DRG; dorsal root ganglion; IB4; isolectin-4; i.pl.; intraplantar; NGS; norma
Specific functioning of Cav3.2 T-type calcium and TRPV1 channels under different types of STZ-diabetic neuropathy
Keywords: [Ca2Â +]i; cytosolic Ca2Â + concentration; DRG; dorsal root ganglia; HMP; holding membrane potential; IB4; isolectin B4; LVA/HVA; low/high voltage activated; NTCN; nonpeptidergic thermal C-type nociceptive (neurons); PCD; peak current density; PDN; periph
Age-related changes of neurochemically different subpopulations of cardiac spinal afferent neurons in rats
Keywords: Senescence; Heart innervation; Afferent neurons; DRG; IB4; N52;
Role of bovine adrenal medulla 22 (BAM22) in the pathogenesis of neuropathic pain in rats with spinal nerve ligation
Keywords: Bovine adrenal medulla 22 (BAM22); Dorsal root ganglia; IB4; Endogenous opioid peptide; Interleukine-1β (IL-1β); Neuropathic pain;
GDNF induces mechanical hyperalgesia in muscle by reducing IBK in isolectin B4-positive nociceptors
Keywords: AHP; after-hyperpolarization; ANOVA; analysis of variance; BK channel; large-conductance voltage- and calcium-activated potassium channel; CDK5; cyclin-dependent kinase 5; DiI; 1,1â²-dioctadecyl-3,3,3â²,3â²-tertamethyllindocarbocyanine perchlorate; DRG
Ectopic uterine tissue as a chronic pain generator
Keywords: CGRP; calcitonin gene-related peptide; DAPI; 4â²,6-diamidino-2-phenylindole; DiI; 1,1â²-dioctadecyl-3,3,3â²,3â²-tertamethyllindocarbocyanine perchlorate; DRG; dorsal root ganglion; EGTA; ethylene glycol tetraacetic acid; FITC; fluorescein isothiocyana
Specificity of peripheral nerve regeneration: Interactions at the axon level
Keywords: AKT/PKB; protein kinase B; BDNF; brain derived neurotrophic factor; cAMP; cyclic adenosine monophosphate; CAMs; cell adhesion molecules; Cdc42; cell division control protein 42 homolog; cGMP; cyclic guanosine monophosphate; ChAT; choline acetyltransferase
The influence of exercise on morphological and neurochemical properties of neurons in rat nodose ganglia
Keywords: Nodose ganglion; Exercise; Treadmill; IB4; N52; Calretinin
Research ReportFunctional endothelin receptors are selectively expressed in isolectin B4-negative sensory neurons and are upregulated in isolectin B4-positive neurons by neurturin and glia-derived neurotropic factor
Keywords: DRG; dorsal root ganglia; ET-1,2,3; endothelin 1,2,3; ETA-R; endothelin receptor A; ETB-R; endothelin receptor B; ETFR; endothelin functional receptors; ETAFR; endothelin functional receptors A; GDNF; glia-derived neurotropic factor; IB4; isolectin B4; NF
Comparative study of voltage-gated sodium channel α-subunits in non-overlapping four neuronal populations in the rat dorsal root ganglion
Keywords: Nav; α-subunits of voltage-gated sodium channel; DRG; dorsal root ganglion; NF200; neurofilaments of MW 200 kDa; IB4; isolectin B4 from Griffonia simplicifolia; TrkA; nerve growth factor high-affinity receptor tyrosine kinase A; TTX-s; tetrodotoxin-sens
Minocycline promotes remyelination in aggregating rat brain cell cultures after interferon-γ plus lipopolysaccharide-induced demyelination
Keywords: neuroinflammation; microglia; oligodendrocyte precursor cells; DIV; day in vitro; IB4; isolectin B4 of Griffonia simplicifolia; IFN-γ; interferon-γ; LPS; lipopolysaccharide; MAP; mitogen-activated protein; MBP; myelin basic protein; MOG; myelin oligoden
Induction of heat shock proteins in the adult rat cerebral cortex following pilocarpine-induced status epilepticus
Keywords: GFAP; glial fibrillary acidic protein; HO-1; heme oxygenase-1; Hsc; heat shock cognate protein; Hsp; heat shock protein; IB4; GSA-isolectin B4; IL-1β; interleukin-1 beta; PBS; phosphate buffered saline; SE; status epilepticus; TNFα; tumor necrosis facto
Upregulation of neuronal nitric oxide synthase in the periphery promotes pain hypersensitivity after peripheral nerve injury
Keywords: peripheral nerve injury; mechanical allodynia; periphery; neuronal nitric oxide synthase; nitric oxide; ATF3; activating transcription factor 3; CCI; chronic constriction injury; cGMP; cyclic guanosine monophosphate; CGRP; calcitonin gene related peptide;
Expression of α1-adrenoceptors on peripheral nociceptive neurons
Keywords: alpha-adrenergic receptor; sensory afferent; skin; dorsal root ganglion; immunohistochemistry; cAMP; cyclic adenosine monophosphate; CGRP; calcitonin gene related peptide; DRG; dorsal root ganglia; IB4; isolectin B4; MBP; myelin basic protein; NF200; neur
Characterization of spinal afferent neurons projecting to different chambers of the rat heart
Keywords: Retrograde tracing; DRG; IB4; N52; Calretinin; Rat heart
Immunohistochemical characteristics of neurons in nodose ganglia projecting to the different chambers of the rat heart
Keywords: Nodose ganglion; Rat heart; Fast Blue; IB4; N52; Calretinin
Expression of the TRPM8-immunoreactivity in dorsal root ganglion neurons innervating the rat urinary bladder
Keywords: TRPM8; Urinary bladder; Dorsal root ganglion; NF200; TRPV1; CGRP; IB4; Rat
Dependence of monocyte chemoattractant protein 1 induced hyperalgesia on the isolectin B4-binding protein versican
Keywords: IB4; MCP-1; versican; sensory neurons; pain; inflammationCCR2, CC chemokine receptor 2; GDNF, glial cell-line derived neurotrophic factor; IB4, isolectin B4; MCP-1, monocyte chemoattractant protein 1; NGF, nerve growth factor; ODN, oligodeoxynucleotide; P
In vivo multimodal imaging of stem cell transplantation in a rodent model of Parkinson's disease
Keywords: 6-OHDA; 6-hydroxydopamine; DMEM; Dulbecco's modified Eagle medium; GFAP; glial fibrillary acidic protein; IB4; Isolectin B4; IODEX-TAT-FITC; dextran coated iron oxide-TAT-fluorescein isothiocyanate; l-DOPA; levadopa; MRI; magnetic resonance imaging; BMSCs
Molecular mechanism for local anesthetic action of eugenol in the rat trigeminal system
Keywords: APs; action potentials; dEMG; digastric electromyogram; IB4; isolectin B4; scRT-PCR; single-cell reverse transcription-polymerase chain reaction; TG; trigeminal ganglion; TRPV1; transient receptor potential vanilloid 1; TTX; tetrodotoxin; VGSCs; voltage-g