Keywords: ad-virDRP1K38A; dominant-negative DRP1; AICAR; 5-aminoimidazole-4-carboxamide ribonucleotide; ATP5; ATP synthase subunit 5; DAG; diacylglycerol; DRP1; dynamin related protein 1; ER; endoplasmic reticulum; FAO; fatty acid beta-oxidation; JC-1; 5,5â²,6,6â
مقالات ISI (ترجمه نشده)
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Keywords: CCCP; Carbonyl cyanide 3-chlorophenylhydrazone; COX IV; Cytochrome c oxidase subunit IV; DAPI; 4â²,6-Diamidino-2-phenylindole dihydrochloride; DMEM; Dulbecco's Modified Eagle Medium; DMSO; Dimethyl sulfoxide; Drp-1; Dynamin-related protein 1; DNPH; 2,4-d
Keywords: AMPK; AMP-activated protein kinase; ATF6; activating transcription factor 6; BNIP3; BCL2/adenovirus E1B 19Â kDa interacting protein 3; CHOP; C/EBP homologous protein; DRP1; dynamin-related protein 1; FIS1; fission protein 1; GRP78; 78Â kDa glucose-regulat
Keywords: Pulmonary artery smooth muscle cells; Trimetazidine; DRP1; Mdivi-1; Proliferation; Pulmonary artery hypertension;
Keywords: Mitochondrial dynamics; Mfn2; Drp1; Mdivi-1; ROS; Vascular smooth muscle cells;
D-chiro-inositol enriched Fagopyrum tataricum (L.) Gaench extract alleviates mitochondrial malfunction and inhibits ER stress/JNK associated inflammation in the endothelium
Keywords: CMC-Na; carboxymethylcellulose sodium; DCI; D-chiro-inositol; DHE; dihydroethidium; Drp1; dynamin-related protein 1; ER; endoplasmic reticulum; FFAs; free fatty acids; HFD; high fat diet; IRE-1α; inositol-requiring enzyme-1α; JNK; Jun n-terminal kinase
Heme oxygenase-1 protects liver against ischemia/reperfusion injury via phosphoglycerate mutase family member 5-mediated mitochondrial quality control
Keywords: ALT; Alanine aminotransferase; Drp1; dynamin-related protein 1; EDTA; ethylenediaminetetraacetic acid; GDH; glutamate dehydrogenase; H&E; hematoxylin&eosin; HO-1; heme oxygenase-1; H/R; hypoxia/reoxygenation; IL; interleukin; I/R; ischemia/reperfusion; LP
Drp1 mediates compression-induced programmed necrosis of rat nucleus pulposus cells by promoting mitochondrial translocation of p53 and nuclear translocation of AIF
Keywords: Intervertebral disc degeneration; Nucleus pulposus cells; Compression; Programmed necrosis; Dynamin-related protein 1 (Drp1); p53; Apoptosis-inducing factor (AIF); LBP; low back pain; IDD; intervertebral disc degeneration; NP; nucleus pulposus; Drp1; dyna
Inhibition of Drp1 protects against senecionine-induced mitochondria-mediated apoptosis in primary hepatocytes and in mice
Keywords: ALT; Alanine aminotransferase; ActD; Actinomycin D; CYP; Cytochrome P450; CQ; Chloroquine; Drp1; Dynamin-related protein 1; DHPAs; Dehydropyrrolizidine alkaloids; DHR; dehydroretronecine; EM; Electron microscopy; GSH; Glutathione; GAPDH; Glyceradehyde-3-p
Role of PARL-PINK1-Parkin pathway in adipocyte differentiation
Keywords: Adipogenesis; Parkin; Peroxisome proliferator-activated receptor-γ (PPARγ); Presenilin associated rhomboid-like protein (PARL); PTEN-induced kinase 1 (PINK1); C/EBPα/β; CCAAT-enhancer-binding protein-α/â β; DRP1; dynamin-related protein-1; FABP4;
Mdivi-1 ameliorates early brain injury after subarachnoid hemorrhage via the suppression of inflammation-related blood-brain barrier disruption and endoplasmic reticulum stress-based apoptosis
Keywords: Subarachnoid hemorrhage; Mdivi-1; Early brain injury; Inflammation; Blood-brain barrier disruption; Apoptosis;
Inhibition of Drp1-mediated mitochondrial fission improves mitochondrial dynamics and bioenergetics stimulating neurogenesis in hippocampal progenitor cells from a Down syndrome mouse model
Keywords: AR; aspect ratio; BrdU; bromodeoxyuridine; CaN; calcineurin; DAPI; 4',6-diamidino-2-phenylindole; DCX; doublecortin; Drp1; dynamin-related protein 1; DS; Down syndrome; L-Opa; long Opa1; Mdivi-1; mitochondrial division inhibitor 1; Mnf2; mitofusin 2; NPCs
Mitochondrial division inhibitor 1 (mdivi-1) enhances death receptor-mediated apoptosis in human ovarian cancer cells
Keywords: Ovarian cancer; mdivi-1; Death ligands; TRAIL; Drp1; Bax/Bak;
Inhibition of Drp1 by Mdivi-1 attenuates cerebral ischemic injury via inhibition of the mitochondria-dependent apoptotic pathway after cardiac arrest
Keywords: AIF; apoptosis-inducing factor; CA-1; cornu ammonis 1; CPR; cardiopulmonary resuscitation; CytC; cytochrome c; DMSO; dimethyl sulfoxide; Drp1; dynamin-related protein1; HE; Hematoxylin-eosin; MAP; mean aortic pressure; Mdivi-1; mitochondrial division in
The combination of thioxodihydroquinazolinones and platinum drugs reverses platinum resistance in tumor cells by inducing mitochondrial apoptosis independent of Bax and Bak
Keywords: Platinum drug resistance; Cisplatin; Mdivi-1; Thioxodihydroquinazolinone; Bax/Bak-independent apoptosis;
Research ReportThe mitochondrial division inhibitor mdivi-1 attenuates spinal cord ischemia-reperfusion injury both in vitro and in vivo: Involvement of BK channels
Keywords: Spinal cord ischemia-reperfusion injury; Mitochondrial fission; Mdivi-1; Mitochondrial dysfunction; BK channels;
A novel strategy for targeted killing of tumor cells: Induction of multipolar acentrosomal mitotic spindles with a quinazolinone derivative mdivi-1
Keywords: Mdivi-1; Acentrosomal mitotic spindle; Oocyte meiosis; SV40 antigens; Mitotic catastrophe;
Inhibition of mitochondrial fission attenuates Aβ-induced microglia apoptosis
Keywords: AD; Alzheimer's disease; Aβ; β-amyloid protein; BALB; Bagg albino; CytC; cytochrome c; DMEM; Dulbecco's modified eagle medium; Drp1; dynamin-related protein 1; FBS; fetal bovine serum; GTP; Guanosine triphosphate; HD; Huntington's disease; Mdivi-1
Cell death induced by 2-phenylethynesulfonamide uncovers a pro-survival function of BAX
Keywords: DKO; double knock out; GFP; green fluorescent protein; MEFs; mouse embryonic fibroblasts; MOMP; mitochondrial outer membrane permeabilisation; PES; 2-phenylethynesulfonamide; SEM; standard error of mean; STS; staurosporine; wt; wild type; Cell death; Mito
Dynamin-related protein Drp1 and mitochondria are important for Shigella flexneri infection
Keywords: Shigella flexneri; Cell death; Cell-to-cell spreading; Drp1; Mitochondria; Mdivi-1;
A selective inhibitor of Drp1, mdivi-1, protects against cell death of hippocampal neurons in pilocarpine-induced seizures in rats
Keywords: Mitochondrial fission; Mdivi-1; Epilepsy; Apoptosis-inducing factor; Cytochrome c;
Mitochondrial fission in endothelial cells after simulated ischemia/reperfusion: role of nitric oxide and reactive oxygen species
Keywords: I/RP; ischemia/reperfusion; EC; endothelial cell; mtROS; mitochondrial reactive oxygen species; H/RO; hypoxia/reoxygenation; Drp1; dynamin-related protein 1; O2â¢â; superoxide; eNOS; endothelial nitric oxide synthase; ETC; electron transport chain; ONO
Ca2+ signaling and gene transcription in glucose-stimulated insulinoma cells
Keywords: L-type Ca 2+ channel; CREB; Egr-1; c-Jun; ERK; Fis-1; mdivi-1