Keywords: dsDNA; double-stranded DNA; MIF; macrophage migration inhibitory factor; Ang-2; angiopoietin 2; CENPF; centromere protein F; Her2/neu; human epidermal growth factor receptor 2; MUC1; mucin 1; IMP2; insulin-like growth factor mRNA-binding family member 2;
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Keywords: Asthma; Rheumatoid arthritis; Risk; Adults; Epidemiology; aOR; Adjusted odds ratio; HOUSES; HOUsing-based index of SocioEconomic Status; MIC; Major histocompatibility complex; NK; Natural killer; OR; Odds ratio; NKG2D; Natural killer group 2D; RA; Rheumat
Keywords: HF; hepatic fibrosis; HSC; hepatic stellate cells; ECM; extracellular matrix; MMPs; matrix degrading metalloproteinases; TIMPs; tissue inhibitors of metalloproteinases; TGF-β; transforming growth factor-beta; NK; Natural killer; NKT; NK like T; NKG2D; na
Keywords: TME; tumour microenvironment; PD-1; programmed cell death 1; PD-L1; programmed death ligand 1; PD-L2; programmed death ligand 2; PTMs; post-translational histone modifications; DNMTi; DNA methyltransferase inhibitor; HDACi; histone deacetylase inhibitor;
Keywords: AA; Alopecia Areata; AID; autoimmune disease; Aire; autoimmune regulator; APC; antigen-presenting cells; APS; autoimmune polyendocrine syndrome; CeD; celiac disease; CTLA; cytotoxic T-lymphocyte-associated protein; CXCL; chemokine (C-X-C motif) ligand; DC
Keywords: ABC; ATP binding cassette; ADCC; antibody-dependent cell-mediated cytotoxicity; ALDH; aldehyde dehydrogenase; CBP; cAMP response element binding protein (CREB)-binding protein; CSC; cancer stem cell; CTC; circulating tumour cell; DAPT; N-[N-(3,5-difluorop
Keywords: AMP; antimicrobial protein; EPI-/- mice; mice lacking envoplakin, periplakin, and involucrin; FISH; fluorescence in situ hybridization; MPO; myeloperoxidase; NKG2D; natural killer group 2D; SPF; specific pathogen free; TPA; tetradecanoylphorbol-13-acetate
Keywords: NK cells; cell therapy; immunotherapy; chimeric antigen receptors; NKG2D;
Keywords: Lymphomagenesis; Tumorigenesis; Microenvironment; NKG2D; Natural killer; Immunosurveillance; Cytotoxic; CD8; Regulatory; PD-1; TGFβ; IL-10; Anergy;
Keywords: 17-AAG; 17-(Allylamino)-17-demethoxygeldanamycin; 17-DMAG; 17-Dimethylaminoethylamino-17-demethoxygeldanamycin; AKT; v-akt murine thymoma viral oncogene homolog; APC; antigen presenting cell; ATM; Ataxia telangiectasia mutated; ATR; Ataxia telangiectasia
Keywords: NK, nature killer cells; CSCs, cancer stem cells; ROS, redox oxygen species; ULBP, UL16-binding proteins; MIC, MHC class I chain–related moleculesCancer stem cells; NK cells; NKG2D; ROS
A compendium of adenovirus genetic modifications for enhanced replication, oncolysis, and tumor immunosurveillance in cancer therapy
Keywords: Ad; adenovirus; ADP; adenovirus death protein; CAR; coxsackievirus and adenovirus receptor; KIR; killer inhibitory receptor; MHCI/HLA; major histocompatibility complex class I; MICA/MICB; MHC-I chain-related A and B proteins; MLP; major late promoter; MTT
HBsAg stimulates NKG2D receptor expression on natural killer cells and inhibits hepatitis C virus replication
Keywords: Hepatitis B surface antigen; Hepatitis C virus; Natural killer cells; NKG2D;
Immunotherapy for acute myeloid leukemia (AML): a potent alternative therapy
Keywords: AML; acute myeloid leukemia; GO; gemtuzumab ozogamacin; PBD; pyrrolobenzodiazepine; HuM196; humanized murine 196; CARs; chimeric antigen receptors; LAA; leukemia associated antigens; TCRT; cell receptor; NKG2D; natural killer group 2 D; MHC; major histoco
IDO1 impairs NK cell cytotoxicity by decreasing NKG2D/NKG2DLs via promoting miR-18a
Keywords: IDO1; miR-18a; NKG2D; NKG2DLs; Immune escape;
Manufacturing development and clinical production of NKG2D chimeric antigen receptor-expressing T cells for autologous adoptive cell therapy
Keywords: acute myeloid leukemia; CAR T; chimeric antigen receptor; gamma retrovirus; Good manufacturing practice cell therapy; multiple myeloma; NKG2D;
Advances in the use of natural receptor- or ligand-based chimeric antigen receptors (CARs) in haematologic malignancies
Keywords: NKG2D; Cytokines; Cell therapy; Immunotherapy; T cell;
In vitro-induced M2 type macrophages induces the resistance of prostate cancer cells to cytotoxic action of NK cells
Keywords: IL-6; Macrophages; CRPC; NK cell cytotoxicity; PD-L1; NKG2D;
The role of the common gamma-chain family cytokines in γδ T cell-based anti-cancer immunotherapy
Keywords: αβ; alpha beta; ADCC; antibody-dependent cellular cytotoxicity; APC; antigen-presenting cell; BrHPP; bromohydrin pyrophosphate; BTLA; B and T lymphocyte attenuator; CAR; chimeric antigen receptor; DC; dendritic cell; γc; common gamma; γδ; gamma delta
Reformation in chimeric antigen receptor based cancer immunotherapy: Redirecting natural killer cell
Keywords: NK cell; natural killer cell; IFN-γ; interferon-γ; IL; interleukin; TNF-α; tumor necrosis factor-α; CCL; C-C motif ligand; GM-CSF; granulocyte-macrophage colony-stimulating factor; ADCC; antibody dependent cell-mediated cytotoxicity; TRAIL; TNF-relate
NKG2D: A versatile player in the immune system
Keywords: NKG2D; NK cells; B1a cells; Effector CD8 T cells; mCMV; LCMV; Cytokines;
Aberrant NKG2D expression with IL-17 production of CD4+ T subsets in patients with type 2 diabetes
Keywords: T2D; type 2 diabetes; NKG2D; the natural killer group 2, member D receptor; CD; cluster of differentiation; IL; interleukin; PMA; phorbol-12-myristate-13-acetate; TCR; T cell receptor; ND; non-diabetic individuals; HbA1c; glycated hemoglobin A1c; IFN-γ;
IL-15 stimulates NKG2D while promoting IgM expression of B-1a cells
Keywords: B-1a cells; IgM; Innate signaling; Interleukin-15; IL; interleukin; i-EC; intestinal epithelial cells; i-IEL; intestinal intraepithelial lymphocytes; NK; natural killer; γc; common gamma; MΦ; macrophage; DC; dendritic cell; NKG2D; natural-killer group 2
Loss of CD28 within CD4+ T cell subsets from cervical cancer patients is accompanied by the acquisition of intracellular perforin, and is further enhanced by NKG2D expression
Keywords: CC; cervical cancer; HPV; human papillomavirus; NKG2D; natural-killer group 2, member D; FS; forward scatter; SS; side scatter; PBMCs; peripheral blood mononuclear cells; CD28; NKG2D; Perforin; CD4+ T cells; Cervical carcinoma;
Original ArticleThe Quantitative and Functional Changes of Postoperative Peripheral Blood Immune Cell Subsets Relate to Prognosis of Patients with Subarachnoid Hemorrhage: AÂ Preliminary Study
Keywords: Clipping surgery; Immune function; Inflammatory cytokines; Lymphocyte subsets; Peripheral blood leukocytes; SAH; GOS; Glasgow Outcome Scale; IFN-γ; Interferon γ; IL-2; Interleukin 2; IVGTT; Intravenous glucose tolerance test; NK; Natural killer; NKG2D;
Attenuated in vitro effects of IFN-α, IL-2 and IL-12 on functional and receptor characteristics of peripheral blood lymphocytes in metastatic melanoma patients
Keywords: NK; natural Killer; CTL; cytotoxic T lymphocytes; MM; metastatic melanoma; NKG2D; natural killer group 2 D; NCR; natural cytotoxicity receptor; KIR; killer cell immunoglobulin-like receptor; HLA; human leukocyte antigen; MICA/B; MHC-class-I-polypeptide-re
Multiple pathways of SIRT6 at the crossroads in the control of longevity, cancer, and cardiovascular diseases
Keywords: ALP; alkaline phosphatase; AMPK; AMP-activated protein kinase; Ang II; angiotensin II; BER; base excision repair; cAMP; cyclic adenosine monophosphate; CDK; cyclin-dependent kinase; CHIP; carboxyl terminus of Hsp70-interacting protein; CLL; chronic lympho
Enhanced antitumor activity of gemcitabine by polysaccharide-induced NK cell activation and immune cytotoxicity reduction in vitro/vivo
Keywords: SEP; A polysaccharide isolated from Strongylocentrotus nudus egg; TLR; toll-like receptor; NKG2D; natural-killer group 2 member D; DAP10; DNAX-associated protein 10; Akt; protein kinase B; MICA; MHC class I-related chain A; sMICA; soluble MHC class I-rela
Modification of cytokine-induced killer cells with folate receptor alpha (FRα)-specific chimeric antigen receptors enhances their antitumor immunity toward FRα-positive ovarian cancers
Keywords: ACT; adoptive cellular immunotherapy; AICD; activation induced cell death; ALL; acute lymphocytic leukemia; AML; acute myeloid leukemia; BsAb; bispecific antibody; CA125; cancer antigen-125; CARs; chimeric antigen receptors; CBMCs; cord blood mononuclear
The histone deacetylase inhibitor SAHA simultaneously reactivates HIV-1 from latency and up-regulates NKG2D ligands sensitizing for natural killer cell cytotoxicity
Keywords: HIV-1; Viral latency; LRA; HDACi; SAHA; NK cell; NKG2D; MICA/B; ULBP2;
Identification of the activating cytotoxicity receptor NKG2D as a senescence marker in zero-hour kidney biopsies is indicative for clinical outcome
Keywords: kidney; NKG2D; senescence; zero-hour biopsy;
Prognostic significance and functional implication of immune activating receptor NKG2D in gastric cancer
Keywords: NKG2D; Gastric cancer; Prognosis; Immune evasion;
Hepatic stellate cell interferes with NK cell regulation of fibrogenesis via curcumin induced senescence of hepatic stellate cell
Keywords: Hepatic fibrosis; Natural killer cell; Hepatic stellate cell; Senescence; Granule exocytosis; 3,4-DCI; 3,4-Dichloroisocoumarin; α-SMA; α-Smooth muscle actin; CCl4; Carbon tetrachloride; CMA; Concanamycin A; DAPI; 4â², 6-Diamidino-2-phenylindole; DMEM;
STAT3 inhibition by STA21 increases cell surface expression of MICB and the release of soluble MICB by gastric adenocarcinoma cells
Keywords: ADAM; a disintegrin and metalloproteinase; APC; allophycocyanin; LDH; lactate dehydrogenase; MICA; major histocompatibility complex class I chain-related molecules A; MICB; major histocompatibility complex class I chain-related molecules B; NKG2D; natural
The expression of NKG2D on porcine IEL and its possible relation to the adaptive intestinal immune system
Keywords: IEL; intraepithelial lymphocytes; EC; enterocytes; NKG2D; natural killer cell receptor; CD; cluster of differentiation; mab; monoclonal antibody; TCR; T cell receptor; MIC; MHC class-I related molecules; ULBP; UL16 binding protein; IL; interleukin; TGF; t
NKG2D ligand expression in Crohn's disease and NKG2D-dependent stimulation of CD8+ T cell migration
Keywords: CD; Crohn's disease; CRP; C-reactive protein; CyTOF; Cytometry by Time of Flight; DAB; diaminobenzidine; EDTA; ethylenediaminetetraacetic acid; FACS; fluorescence-activated cell sorting; FMO; fluorescence minus one; GM-CSF; granulocyte-macrophage colony-s
DNT cell inhibits the growth of pancreatic carcinoma via abnormal expressions of NKG2D and MICA in vivo
Keywords: DNT cell; Pancreatic carcinoma; NKG2D; MICA;
Short communicationHedgehog signaling regulates PDL-1 expression in cancer cells to induce anti-tumor activity by activated lymphocytes
Keywords: Hh; Hedgehog; MAML3; mastermind-like3; RBPJ; recombination signal binding protein for immunoglobulin-kappa-J region; PD-1; programmed death-1; PDL-1; programmed death ligand-1; Smo; Smoothened; PSK; protein-bound polysaccharide; NKG2D; natural-killer grou
Characterization of 5′ promoter and exon 1–3 polymorphism of the RAET1E gene
Keywords: RAET1E; ULBP4; NKG2D; Ligand; NK cell; Immunosurveillance
Discovery of a new selective inhibitor of A Disintegrin And Metalloprotease 10 (ADAM-10) able to reduce the shedding of NKG2D ligands in Hodgkin's lymphoma cell models
Keywords: Hodgkin's lymphoma; NKG2D-L; ADAM-10 inhibitors; Sulfonamido-based hydroxamates; HL; Hodgkin's lymphoma; ADAM; A Disintegrin And Metalloproteinase; ALCAM; activated leukocyte cell adhesion molecule; EOC; epithelial ovarian cancer; NK; natural killer; NKG2
Contradicting roles of miR-182 in both NK cells and their host target hepatocytes in HCV
Keywords: Natural killer cells; HCV; NKG2A; NKG2D; ULBP2; miR‑182
Alopecia areata: Animal models illuminate autoimmune pathogenesis and novel immunotherapeutic strategies
Keywords: Alopecia areata; Autoimmunity; C3H; HeJ mouse model; Alopecia areata humanized mouse model; Hair follicle; T lymphocytes; NKG2D; Immune privilege; Janus kinase(JAK)-1; Jak3
Human Natural Killer cell expression of ULBP2 is associated with a mature functional phenotype
Keywords: Human; Natural Killer cells; ULBP2; NKG2D; Phenotype;
Exosomes and nanotubes: Control of immune cell communication
Keywords: APC; Antigen presenting cell; Cdc42; Cell division control protein 42; DC; Dendritic cell; EBV; Epstein-Barr virus; ESCRT; Endosomal sorting complex required for transport; HIV; Human immunodeficiency virus; ICAM-1; Intercellular adhesion molecule 1; IgA;
Enhancing NK cell cytotoxicity by miR-182 in hepatocellular carcinoma
Keywords: B2m; beta-2-microglobulin; cDNA; complementary DNA; DMEM; Dulbecco's modified eagle's medium; FBS; fetal bovine serum; GzmB; granzyme B; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; IFN-γ; interferon gamma; KIRs; killer immunoglobulin recep
The Paracaspase MALT1
Keywords: NF-κB signaling; Protease; Caspase; Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1); ABC; activated B cell-like; ABC-DLBCL; activated B cell-like diffuse large B cell lymphoma; Ac; acetyl; ALL; acute lymphomblastic leukemia; AM
Adenovirus serotype 5 E1A expressing tumor cells elicit a tumor-specific CD8+ T cell response independent of NKG2D
Keywords: Adenovirus E1A; NKG2D; NKG2D ligands; NK cells; CD8+ T cells; Tumor immunologyE1A, early region 1 A; Ad, adenovirus; NKG2D, natural killer group 2 D; MCA, methylcholanthrene; OVA, ovalbumin; NK, natural killer; WT, wildtype; RAE-1, retinoic acid early ind
NKG2A expression and impaired function of NK cells in patients with new onset of Graves' disease
Keywords: GD; NK; NKG2A; NKP30; KIR3DL1; NKG2D
Viral strategies to modulate NKG2D-ligand expression in Human Cytomegalovirus infection
Keywords: Human cytomegalovirus (HCMV); Natural Killer cells; Immune evasion; NKG2D; MICA; ULBP; UL16; UL142;
Delivery of human NKG2D-IL-15 fusion gene by chitosan nanoparticles to enhance antitumor immunity
Keywords: Chitosan nanoparticle; NKG2D; IL-15; Gene vaccine; Tumor; MICA; major histocompatibility complex class I chain-related protein A; DD; degree of deacetylation; PBS; phosphate buffer saline; NP; nanoparticle; DLS; dynamic light scattering; ELISA; enzyme-lin