Keywords: SA; sinapic acid; BLM; bleomyci; BALF; bronchoalveolar lavage fluid; LDH; lactate dehydrogenase; ALP; alkaline phosphatase; ROS; reactive oxygen species; RNS; reactive nitrogen species; TNFα; tumor necrosis factor-alpha; IL-β; interleukin-1β; MPO; myel
مقالات ISI (ترجمه نشده)
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Keywords: Nicorandil; Silica; TNF-α; TGF-β1; Nrf-2; HO-1; iNOS;
Keywords: AA; Antimycin A; ADFI; average daily feed intake; ADG; average daily gain; AMPK; AMP-activated protein kinase; ATP; adenosine triphosphate; CAT; catalase; CR; caloric restriction; CS; citrate synthase; cyt b; cytochrome b; ESRRA; estrogen-related receptor
Keywords: 8-OHdG; 8-hydroxy-2-deoxyguanosine; Îym; mitochondrial membrane potential; AMPK; AMP-activated protein kinase; apoB; apolipoprotein B; AST; aspartate transaminase; ALT; alanine transaminase; ATP; adenosine triphosphate; CPT-1; carnitine palmitoyl-transfe
Keywords: MD; Mediterranean diet; HT; hydroxytyrosol; IUPAC; International Union of Pure and Applied Chemistry; ADME; absorption, distribution, metabolism and excretion processes; EVOO; extra virgin olive oil; HTA; HT acetate; Tyr; tyrosol; EFSA; European Food Safe
Keywords: ALP; Autophagy Lysosome Pathway; LC-MS; Liquid Chromatography Mass Spectrometry; NMR; Nuclear Magnetic Resonance; Nrf-2; NF-E2-related factor 2; PKC; Protein Kinase C; PDR; Proteome Damage Responses; PN; Proteostasis Network; ROS; Reactive Oxygen Species;
Keywords: Garlic; Alcoholic liver disease; Reactive oxygen species; Nrf-2; Kupffer cells; Adiponectin; AC; alcoholic cirrhosis; ACC; acetyl-CoA carboxylase; AF; alcoholic fibrosis; AFL; alcoholic fatty liver; AGE; aged garlic extract; AH; alcoholic hepatitis; ALD;
Keywords: Parkinson's disease; Ghrelin; Dementia; AHN; adult hippocampal neurogenesis; AD; Alzheimer's Disease; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPK; AMP-activated protein kinase; AB; amyloid-β; ATG; autophagy-related; BBB; blood brain
Keywords: Nrf-2; Reporter mouse; Bioluminescence; In vivo imaging; Parkinson's disease; Anti-oxidant responsive elements; ARE-luc2 mouse; Oxidative stress;
Keywords: 3-MP; 3-mercaptopyruvate; 3-MST; 3-mercaptopyruvate sulfurtransferase; AAT; aspartate amino transferase; AE1; anion exchanger-1; AGEs; advanced glycation end products; AKI; acute kidney injury; AMPK; AMP-activated protein kinase; AT1; angiotensin receptor
Keywords: Curcumin; Neuropathic pain (NP); Inflammatory pain; Depression; Bioavailability; ACE; angiotensin converting enzyme; AP-1; activator protein-1; AKT; protein kinase B; BDMC; bisdemethoxycurcumin; BDNF; brain-derived neurotrophic factor; CAT; catalase; CS;
Keywords: ACSL4; acyl-CoA synthetase long-chain family member 4; AD; Alzheimer's disease; ARE; antioxidant-responsive element; ANT; adenine nucleotide translocase; AP-1; activator protein-1; ATP; adenosine triphosphate; Bak; Bcl-2 antagonist/killer; BCEC; brain c
Keywords: CAD; coronary artery diseases; DIC; disseminated intravascular coagulation, I/R, ischemia/reperfusion; MPI; myocardial perfusion imaging; SCI; spinal cord injury; ED; erectile dysfunction; AUC; area under the concentration-time curve; cAMP; cyclic adenosi
Keywords: BCL-2; B-cell lymphoma protein; TEM; transmission electron microscopy; CEC; corneal endothelial cells; ROS; reactive oxygen species; RNS; reactive nitrogen species; UV; ultraviolet; Nrf-2; nuclear erythroid factor 2; H2O2; hydrogen peroxide; mtDNA; mitoch
Keywords: ADMET; absorption, distribution, metabolism, excretion, toxicity; AHR; aryl hydrocarbon receptor; AUC; area under the curve; BVU; (E)-5-(2-bromovinyl) uracil; CAR; constitutive androstane receptor; cMOAT; Canalicular multispecific organic anion transporte
Keywords: AGEs; advanced glycation end products; LA; alpha lipoic acid; BAEC; bovine aortic endothelial cells; BCA; bicinchoninic acid; BH4; tetrahydrobiopterin; CaI; calcium ionophore; CAT; catalase (EC 1.11.1.6); CMD; cardiometabolic disease; CVD; cardiovascular
Keywords: Stem/progenitor cells; Sp1; P2X7 receptors; P2Y13 receptors; GSK3; Nrf-2; DUSP; MAPK signaling; (AIS); axon initial segment; (ATF3); activating transcription factor 3; (BBG); Brilliant Blue G; (BDNF); brain-derived neurotrophic factor; (bFGF); basic fibro
Keywords: Hematopoietic stem and progenitor cells; Nrf-2; NF-κB; Radioprotection; Hematopoiesis;
Keywords: ANOVA; analysis of variance; ARS; acute restraint stress; CAT; catalase; CNS; central nervous system; FST; forced swimming test; GSSG; glutathione disulfide; GPx; glutathione peroxidase; GR; glutathione reductase; GSH; reduced glutathione; H2O2; hydrogen
Keywords: Cyclophosphamide; Diallyl disulfide; Urotoxicity; Cytochrome P450; Oxidative stress; Nrf-2;
Keywords: AICAR; 5â²aminoimidazole-4-carboxyamide-ribonucleoside; AD; Alzheimer's disease; ATF-2; activating transcription factor-2; AMPK; AMP-activated protein kinase; Bnip3; BCL2/adenovirus E1B 19Â kDa interacting protein 3; BnipL/Nix; BCL2/adenovirus E1B 19Â
Keywords: IGF-I; insulin-like growth factor-I; MSC; marrow-derived mesenchymal stem cell; Nrf-2; nuclear factor erythroid 2-related factor 2; PTH; parathyroid hormone; ROS; reactive oxygen species; HO; heme oxygenase; iNOS; independent inducible NOS; Insulin-like g
Keywords: ATF6; activating transcription factor 6; BiP; heat shock 70 kDa protein 5 (glucose-regulated protein, 78 kDa); GSMA; gel shift mobility assay; HO-1; heme oxygenase 1; IL-1β; interleukin 1 beta; IRE1α; inositol-requiring protein 1; NF-κB; nuclear fact
Nuclear trapping of inactive FOXO1 by the Nrf2 activator diethyl maleate
Keywords: FOXO; DAF-16; Glutathione; Stress response; Nrf-2; Thiols; Nuclear export;
Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration
Keywords: ER; endoplasmic reticulum; AMD; age-related macular degeneration; RPE; retinal pigment epithelium; PUFAs; polyunsaturated fatty acids; ROS; reactive oxygen species; NRF-2; nuclear factor-erythroid 2-related factor-2; ARE; antioxidant response element; Kea
Ellagic acid impedes carbontetrachloride-induced liver damage in rats through suppression of NF-kB, Bcl-2 and regulating Nrf-2 and caspase pathway
Keywords: CCl4; carbon tetrachloride; EA; ellagic acid; EDTA; ethylenediaminetetraacetic acid; FUDAM; Firat University Experimental Animals Research Institute; ip; intraperitoneal; MDA; malondialdehyde; NF-kB; nuclear factor kappa B; PAGE; polyacrylamide gel electr
Galangin induces cell death by modulating the expression of glyoxalase-1 and Nrf-2 in HeLa cells
Keywords: Glyoxalase-1; Nrf-2; Galangin; Apoptosis;
A novel antioxidant peptide, purified from Bacillus amyloliquefaciens, showed strong antioxidant potential via Nrf-2 mediated heme oxygenase-1 expression
Keywords: Bacillus amyloliquefaciens CBSYD1; Antioxidant; Antimicrobial; Nrf-2; Heme oxygenase-1;
p-Coumaric acid mediated protection of H9c2 cells from Doxorubicin-induced cardiotoxicity: Involvement of augmented Nrf2 and autophagy
Keywords: p-coumaric acid; Doxorubicin; Cardiotoxicity; Nrf-2; H9c2;
Nicotinamide riboside attenuates alcohol induced liver injuries via activation of SirT1/PGC-1α/mitochondrial biosynthesis pathway
Keywords: ADH; alcohol dehydrogenase; ALD; Alcoholic liver disease; ALDH; aldehyde dehydrogenase; CPT-1α; carnitine palmitoyl transterase-1α; CR; calorie restriction; CS; citrate synthase; CYP2E1; cytochrome P450 2E1; FASN; fatty acid synthase; NAD+; nicotinamide
Embryotropic effects of vascular endothelial growth factor on porcine embryos produced by in vitro fertilization
Keywords: Vascular endothelial growth factor (VEGF); Apoptosis; Nrf-2; Viable embryos;
Chrysin: Sources, beneficial pharmacological activities, and molecular mechanism of action
Keywords: Passifloraceae; Passiflora caerulea; Chrysin; Pharmacological activities; Bioavailability; Molecular docking; AC; adenylyl cyclase; AGEs; advanced glycation end products; ACR; acrylamide; AHR; aryl hydrocarbon receptor; AMPK; AMP-activated protein kinase;
Protective action of Crateva nurvala Buch. Ham extracts against renal ischaemia reperfusion injury in rats via antioxidant and anti-inflammatory activities
Keywords: ACN; acetonitrile; AKI; acute kidney injury; CLE; C. nurvala leaves extract; CBE; C. nurvala bark extract; DGF; delayed graft function; GSH; glutathione; I/R; ischaemia/ reperfusion; IL-6; interleukin-6; MDA; malondialdehyde; Nrf-2; nuclear factor erythro
Targeting Keap-1/Nrf-2 pathway and cytoglobin as a potential protective mechanism of diosmin and pentoxifylline against cholestatic liver cirrhosis
Keywords: DS; diosmin; PTX; pentoxifylline; BDL; bile duct ligation; ROS; reactive oxygen species; GSH; reduced glutathione; MDA; malondialdehyde; SOD; superoxide dismutase; TGF-β; transforming growth factor-beta; HYP; hydroxyproline; P38âMAPK; P38 mitogen activ
Nrf-2 transcriptionally activates P21Cip/WAF1 and promotes A549â¯cell survival against oxidative stress induced by H2O2
Keywords: Oxidative stress; Nrf-2; p21; p53; Transcriptional activation; Cancer;
IL-6 family cytokines: Key inflammatory mediators as biomarkers and potential therapeutic targets
Keywords: BALF; bronchoalveolar lavage fluid; CAC; colitis-associated cancer; CAF; cancer associated fibroblast; ccRCC; clear cell renal cell carcinoma; CLC; cardiotrophin-like cytokine; CML; chronic myeloid leukemia; CNTF; ciliary neurotrophic factor; COPD; chroni
Sarcodon imbricatus polysaccharides protect against cyclophosphamide-induced immunosuppression via regulating Nrf2-mediated oxidative stress
Keywords: Sarcodon imbricatus; Polysaccharides; Immunomodulatory; Nrf-2; Oxidative stress;
Response of intestinal HT-29 cells to the trichothecene mycotoxin deoxynivalenol and its sulfated conjugates
Keywords: DON; deoxynivalenol; DON-3-Sulf; deoxynivalenol-3-sulfate; DON-15-Sulf; deoxynivalenol-15-sulfate; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; Keap-1; kelch-like ECH-associated protein 1; Nrf-2; nuclear factor (erythroid-derived 2)-like 2; γ-GCL; ga
Targeting the NRF-2/RHOA/ROCK signaling pathway with a novel aziridonin, YD0514, to suppress breast cancer progression and lung metastasis
Keywords: YD0514; Aziridonin; Breast cancer; Metastasis; NRF-2/RHOA/ROCK pathway; Oridonin; BSA; bovine serum albumin; CFL; cofilin; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; EMT; epithelial-mesenchymal transition; ER; estrogen receptor; F
Bio-accessible milk casein derived tripeptide (LLY) mediates overlapping anti- inflammatory and anti-oxidative effects under cellular (Caco-2) and in vivo milieu
Keywords: Bioactive peptide; Oxidative stress; Anti-oxidative enzyme; Nrf-2; Immuno-modulation; Bio-accessibility;
Cytoprotection of lipoic acid against toxicity induced by saxitoxin in hippocampal cell line HT-22 through in silico modeling and in vitro assays
Keywords: ARE; antioxidant response element; BBB; blood brain barrier; CNS; central nervous system; dc-STX; dc-saxitoxin; DFT; density functional simulation; DHLA; dihidrolipoic acid; DMEM; Dulbenco's Modified Eagles Medium containing high glucose; DMSO; dimetils
Mitochondria as pharmacological targets in Down syndrome
Keywords: AD; Alzheimer's disease; AGO; Argonaute proteins; AMPK; AMP-activated protein kinase; ANTs; adenine nucleotide translocators; AK; adenylate kinase; APP; amyloid-β precursor protein; ASD; autism spectrum disorder; CAT; catalase; CNS; central nervous syste
From stroke to neurodegenerative diseases: The multi-target neuroprotective effects of 3-n-butylphthalide and its derivatives
Keywords: 2-VO; 2 vessel occlusion; Aβ; amyloid-β protein; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APP; amyloid precursor protein; Br-NBP; 3-butyl-6-bromo-1(3âH)-isobenzofuranone; BZP; sodium(±)-5-bromo-2-(a-hydroxypentyl) benzoate; CFDA
Balasubramide derivative 3C modulates microglia activation via CaMKKβ-dependent AMPK/PGC-1α pathway in neuroinflammatory conditions
Keywords: AMPK; AMP-activated protein kinase; CaMKKβ; calcium/calmodulin-dependent protein kinase kinase beta; CBF; cerebral blood flow; CCA; common carotid artery; EBSS; glucose-free Earle's balanced salt solution; ECA; external carotid artery; ELISA; cytokine en
Protective effects of Schisandrin B on cigarette smoke-induced airway injury in mice through Nrf2 pathway
Keywords: Schisandrin B; Cigarette smoke; Lung inflammation; NF-κB; Nrf-2;
Linarin could protect myocardial tissue from the injury of Ischemia-reperfusion through activating Nrf-2
Keywords: Linarin; Ischemia-reperfusion injury; Myocardial cell; Oxidative stress; Nrf-2;
Silymarin prevents NLRP3 inflammasome activation and protects against intracerebral hemorrhage
Keywords: Silymarin; ICH; NLRP3; Inflammasome; NF-κB-P65; Nrf-2;
B-vitamin and choline supplementation increases neuroplasticity and recovery after stroke
Keywords: BDNF; Brain derived neurotrophic factor; CD; Control diet; FADD; Folic acid deficient diet; OGD; Oxygen glucose deprivation; Nrf-2; Nuclear factor (erythroid-derived 2)-like2; MTHFR; Methylenetetrahydrofolate reductase; SOD2; Superoxide dismutase 2; SD; S
The protective effect of platelet released growth factors and bone augmentation (Bio-Oss®) on ethanol impaired osteoblasts
Keywords: ALP; alkaline phosphatase; ARE; antioxidance response element; °C; degree Celsius; CTB; Cell TiterBlue cell viability assay; EGF; epidermal growth factor; EtOH; Ethanol; FCS; fetal calf serum; FGF; fibroblast growth factor; G; gravitational; h; hour; H;
Astrocyte elevated gene-1 (AEG-1) and the A(E)Ging HIV/AIDS-HAND
Keywords: Astrocytes; Aging; HIV-associated neurocognitive disorders; Neuroinflammation; ER/Nucleolar/Oxidative stress; Excitotoxicity; Aβ; amyloid beta; AEG-1; astrocyte elevated gene-1; AD; Alzheimer's disease; AIDS; acquired immune deficiency syndrome; ARE; a