Keywords: HCV; 3a; HVR1; NS3; NS5B; Phylogentic; Analysis; Quasispecies; NGS;
مقالات ISI (ترجمه نشده)
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Keywords: DC; dendritic cell; tolDCs; tolerogenic dendritic cells; PD-1; programmed cell death 1; PD-L1/PD-L2; programmed cell death ligand 1/2; 17XNL; nonlethal 17X strains; BCG; Mycobacterium bovis Bacillus Calmette Guérin; BMDCs; bone marrow-derived dendritic c
Keywords: Bovine viral diarrhea; Diagnosis; Serology; NS3; Epitope
Mathematical and simulation analysis of contention resolution mechanism for IEEE 802.11ah networks
Keywords: IEEE802.11ah; Restricted Access Window; DCF; Markov Model; NS3;
Pan-NS3 protease inhibitors of hepatitis C virus based on an R3-elongated pyrazinone scaffold
Keywords: Hepatitis C; NS3; Genotype 3; Resistance; Pyrazinone;
Immunoinformatics and molecular docking studies reveal potential epitope-based peptide vaccine against DENV-NS3 protein
Keywords: Immunoinformatics; Dengue; NS3; Peptide design; Epitopes; Vaccine; MHC; CTL;
Hypericin inhibits hepatitis C virus replication via deacetylation and down-regulation of heme oxygenase-1
Keywords: Hepatitis C virus (HCV); Hypericin; Epigenetic; Deacetylation; HCV; Hepatitis C virus; NS5A; non-structure protein 5A; NS3; non-structure protein 3; HO-1; heme oxygenase 1; 5-Aza-dC; 5-aza-2â²-deoxycytidine; DAAs; direct acting antivirals; PCR; polymeras
Codon usage variation of Zika virus: The potential roles of NS2B and NS4A in its global pandemic
Keywords: ZIKV; Zika virus; NS1; non-structural protein NS1; E; envelope protein; NS3; non-structural protein NS3; C; anchored capsid protein; prM; membrane glycoprotein precursor; NS2A; non-structural protein NS2A; NS2B; non-structural protein NS2B; NS4A; non-stru
The effect of the hepatitis C virus (HCV) NS3 protein on the expression of miR-150, miR-199a, miR-335, miR-194 and miR-27a
Keywords: HCV; Chronic hepatitis; NS3; microRNA; LX-2; Fibrosis;
Bluetongue Disabled Infectious Single Animal (DISA) vaccine: Studies on the optimal route and dose in sheep
Keywords: Bluetongue virus; Vaccine; NS3; Optimal route; Application; Dose;
Polymorphisms associated with resistance to protease inhibitors in naïve patients infected with hepatitis C virus genotype 1 in Argentina: Low prevalence of Q80K
Keywords: Hepatitis C virus; Resistance; NS3; Direct-acting antiviral; Protease inhibitor; Q80K;
Structure and sequence based functional annotation of Zika virus NS2b protein: Computational insights
Keywords: Zika virus; NS3; NS2b; Computational alanine scanning mutagenesis; Protein disorder; Transmembrane domains; Flavivirus;
Characterization of the Zika virus two-component NS2B-NS3 protease and structure-assisted identification of allosteric small-molecule antagonists
Keywords: Zika virus; Protease; NS3; NS2B; Inhibitors; Flavivirus; AC3; active caspase 3; DENV; Dengue virus; EdU; 5-ethynyl-2â²-deoxyuridine; HRP; horseradish peroxidase; hfNPCs; human fetal neural progenitors; JEV; Japanese encephalitis virus; MBP; myelin basic
Synthesis, physicochemical and biological studies of technetium-99m labeled tacrine derivative as a diagnostic tool for evaluation of cholinesterase level
Keywords: Tac; tacrine (1,2,3,4-tetrahydroacridin-9-amine); AD; Alzheimer's disease; AChE; acetylcholinesterase; CNS; central nervous system; IC50; half maximal inhibitory concentration; BM; biologically active molecule; BFCA; Bifunctional Coupling Agent; NS3; tr
Alteration of N-glycan expression profile and glycan pattern of glycoproteins in human hepatoma cells after HCV infection
Keywords: ACA; Amaranthus caudatus agglutinin; AFP; alpha-fetoprotein; ANXA2; annexin A2; ECA; Erythrina cristagalli agglutinin; FUT8; α1,6-fucosyltransferase 8; HCC; hepatocellular carcinoma; HCV; Hepatitis C virus; HCVcc; HCV cell culture; HSP90B1; heat shock pr
The NS3 and NS4A genes as the targets of RNA interference inhibit replication of Japanese encephalitis virus in vitro and in vivo
Keywords: JEV; Japanese encephalitis virus; DENV; dengue virus; HCV; hepatitis C virus; BVDV; bovine viral diarrhea virus; NS3; non-structural 3 protein; C; capsid protein; M; membrane protein; E; envelope protein; min; minute; h; hour; hpt; hours post transfection
Detection and isolation of Bluetongue virus from commercial vaccine batches
Keywords: Bluetongue virus; Vaccine safety; Real-time PCR; NS3; VP1;
Heterogeneous genomic locations within NS3, NS4A and NS4B identified for genotyping and subtyping of Hepatitis C virus: A simple genome analysis approach
Keywords: bs; bootstrap; GTR; general time reversible; HCV; Hepatitis C virus; MCL; maximum composite likelihood; ML; maximum likelihood; N-J; neighbor-joining; RA; reference alignment; SVR; sustained virological response; HCV; Genotyping; Subtyping; Phylogenetic a
Long non-coding RNA GAS5 inhibited hepatitis C virus replication by binding viral NS3 protein
Keywords: Long non-coding RNA; GAS5; Hepatitis C virus; NS3;
Polyethylenimine-based polyplex delivery of self-replicating RNA vaccines
Keywords: Replicon-RNA; Self-replicating vaccine; Polyplexes; Blood dendritic cells; Intracellular delivery; Humoral and cellular immunity; Adjuvant; Influenza vaccines; 7-AAD; 7-aminoactinomycin D; BPPcysMPEG; S-[2,3-bispalmitoyiloxy-(2R)-propyl]-R-cysteinyl-amido
NS5A resistance leading to failure of 24-week therapy with sofosbuvir/ledipasvir and ribavirin for the treatment of hepatitis C genotype 1a infection in a HIV-1 co-infected patient
Keywords: ALT; alanine aminotransferase; AST; aspartate aminotransferase; cART; combination antiretroviral therapy; DAA; direct-acting antiviral; DDI; drug-drug interaction; EOTR; end-of-treatment response; GT; genotype; HCV; hepatitis C virus; HIV-1; human immun
ReviewThe importance of resistance to direct antiviral drugs in HCV infection in clinical practice
Keywords: HCV; hepatitis C virus; DAA; direct-acting antiviral agent; NS3; non-structural protein 3; NS5A; non-structural protein 5A; NS5B; non-structural protein 5B; RAVs; resistance associated variants; IP-10; interferon-gamma-inducible protein 10; IFNL4; interfe
Case ReportRapid clearance of HCV-related splenic marginal zone lymphoma under an interferon-free, NS3/NS4A inhibitor-based treatment. A case report
Keywords: HCV; hepatitis C virus; NHL; non-Hodgkin lymphoma; SMZL; splenic marginal zone lymphoma; NS3; non-structural protein 3; IFN; interferon; RBV; ribavirin; FDV; faldaprevir; DLV; deleobuvir; DAA; direct-acting antiviral agent; MALT; mucosa-associated lymphoi
Previous failure of interferon-based therapy does not alter the frequency of HCV NS3 protease or NS5B polymerase inhibitor resistance-associated variants: longitudinal analysis in HCV/HIV co-infected patients
Keywords: HCV; Direct-acting antivirals; Resistance-associated variants (RAVs); NS3; NS5B; Peg-IFN;
HCV NS3 quasispecies in liver and plasma and dynamics of telaprevir-resistant variants in breakthrough patients assessed by UDPS: A case study
Keywords: HCV; NS3; Diversity; Viral quasispecies; Resistance associated mutations; Ultra-deep pyrosequencing
Detection of the NS3 Q80K polymorphism by Sanger and deep sequencing in hepatitis C virus genotype 1a strains in the UK
Keywords: Lineage; NS3; protease inhibitors; Q80K; simeprevir
Hepatitis C virus NS3 protein enhances cancer cell invasion by activating matrix metalloproteinase-9 and cyclooxygenase-2 through ERK/p38/NF-κB signal cascade
Keywords: AP-1; activation protein-1; CMA; cell matrix adhesion; COX-2; cyclooxygenase-2; ECM; extracellular matrix; ELISA; enzyme-linked immunosorbent assay; EMSA; electrophoretic mobility shift assay; ERK; extracellular signal-regulated kinase; HBV; hepatitis B v
ReviewNatural history and treatment of HCV/HIV coinfection: Is it time to change paradigms?
Keywords: HCV; hepatitis C virus; HIV; human immunodeficiency virus; MSM; men who have sex with men; iv; intravenous; PegIFNα; pegylated interferon-alfa; RBV; ribavirin; SVR; sustained virological response; GT; genotype; DAA; direct-acting antiviral; NS3; nonstruc
The dengue virus NS5 protein as a target for drug discovery
Keywords: DENV; dengue virus; DHF; dengue hemorrhagic fever; NS5; non-structural protein 5; MTase; methyltransferase; GTase; guanylyltransferase; RdRp; RNA-dependent RNA polymerase; NS3; non-structural protein 3; nt; nucleotide; ss; single strand; ds; double strand
UK-1 and structural analogs are potent inhibitors of hepatitis C virus replication
Keywords: Hepatitis C; NS3; Helicase; Inhibitor;
Suramin inhibits helicase activity of NS3 protein of dengue virus in a fluorescence-based high throughput assay format
Keywords: DENV, dengue virus serotype; HCV, hepatitis C virus; NS3, non-structural protein 3; FL, full length; H, helicase domain; Trx, thioredoxin; RFU, relative fluorescence unitDengue virus; NS3; RNA helicase; ATP hydrolysis; Suramin; Counter screen
VP2-serotyped live-attenuated bluetongue virus without NS3/NS3a expression provides serotype-specific protection and enables DIVA
Keywords: Bluetongue virus; DISA vaccine; Serotype; DIVA; NS3; Reverse genetics;
Synthesis, physicochemical and biological evaluation of technetium-99m labeled lapatinib as a novel potential tumor imaging agent of Her-2 positive breast cancer
Keywords: Lapatinib; Her-2 receptor; Technetium; Radiopharmaceutical; SKOV-3; Her-2; Human Epidermal Growth Factor Receptor 2; IHC; immunohistochemical; FISH; fluorescent in situ hybridisation; CISH; chromogenic in situ hybridisation; HPLC; high-performance liquid
Oral administration of genetically modified Bifidobacterium displaying HCV-NS3 multi-epitope fusion protein could induce an HCV-NS3-specific systemic immune response in mice
Keywords: Bifidobacterium; Mucosal vaccine; HCV; NS3;
The intracellular inhibition of HCV replication represents a novel mechanism of action by the innate immune Lactoferrin protein
Keywords: HCV; Hepatitis C virus; hLF; human Lactoferrin; LF; Lactoferrin; HIV; human immunodeficiency virus; HSV1; herpes simplex virus type 1; CMV; cytomegalovirus; RDRP; RNA-dependent RNA polymerase; NGS; normal goat serum; WGA; wheat germ agglutinin; IPTG; isop
Vinylated linear P2 pyrimidinyloxyphenylglycine based inhibitors of the HCV NS3/4A protease and corresponding macrocycles
Keywords: HCV; NS3; Protease inhibitors; Macrocyclization; Phenylglycine; Metathesis;
Research ArticleLimited impact of IL28B genotype on response rates in telaprevir-treated patients with prior treatment failure
Keywords: DAA; direct-acting antiviral; HBV; hepatitis B virus; HCV; hepatitis C virus; HIV; human immunodeficiency virus; LLOD; lower limit of detection; LLOQ; lower limit of quantification; NS3; non-structural protein 3; OR; odds ratio; PCR; polymerase chain reac
HCV versus HIV drug discovery: Déjà vu all over again?
Keywords: HIV; HCV; Antivirals; Clinical development; Combination therapy; Single tablet regimen; Protease; Integrase; Polymerase; NS3; NS5A; Nucleoside; Non-nucleoside; NNI; CCR5;
Research ArticleDual oral therapy with daclatasvir and asunaprevir for patients with HCV genotype 1b infection and limited treatment options
Keywords: HCV; hepatitis C virus; DAA; direct-acting antiviral; PegIFN-α/RBV; peginterferon alfa and ribavirin; SVR; sustained virologic response; HIV; human immunodeficiency virus; NS5A; non-structural protein 5A; NS3; non-structural protein 3; ALT; alanine amino
Mapping B-cell linear epitopes of NS3 protein of bovine viral diarrhea virus
Keywords: BVDV; NS3; Epitopes
Development of Robust Hepatitis C Virus Genotype 4 Subgenomic Replicons
Keywords: Pan-Genotypic; Q34R; Cured Huh-7 Cell Line; GS-5885; GS-7977; GT; genotype; HCV; hepatitis C virus; NS3; nonstructural protein 3; neo; neomycin;
Dynamic changes in HCV RNA levels and viral quasispecies in a patient with chronic hepatitis C after telaprevir-based treatment
Keywords: HCV; hepatitis C virus; SVR; sustained viral response; Peg-IFN; pegylated interferon α; NS3; non-structural 3; HLA; human leukocyte antigen; AA; amino acid; Hepatitis C virus; Antiviral treatment; Direct acting antiviral (DAA); Protease inhibitor; Telapr
Translocase of outer mitochondrial membrane 70 induces interferon response and is impaired by hepatitis C virus NS3
Keywords: HCV; Tom70; MAVS; IFN; IRF-3; NS3;
Research ArticleThe CXCL1 rs4074 A allele is associated with enhanced CXCL1 responses to TLR2 ligands and predisposes to cirrhosis in HCV genotype 1-infected Caucasian patients
Keywords: CXCL1; CXC chemokine-ligand-1; HCV; hepatitis C virus; TLR; Toll-like receptor; ELISA; enzyme-linked immunosorbent assay; NS3; non-structural protein 3; PBS; phosphate buffered saline; OR; odds ratio; CI; confidence interval; CXCL1; rs4074; Polymorphism;
Evidence of West Nile virus lineage 2 circulation in Northern Italy
Keywords: Culex pipiens; Collared dove; Streptopelia decaocto; NS3; NS5; Phylogenetic analysis; West Nile virus lineage 2
Monoclonal antibodies against dengue NS2B and NS3 proteins for the study of protein interactions in the flaviviral replication complex
Keywords: Dengue; Flavivirus; NS3; NS2B; Monoclonal antibody;
Establishment of a robust dengue virus NS3-NS5 binding assay for identification of protein-protein interaction inhibitors
Keywords: Dengue virus; NS3; NS5; Wheat-germ cell-free protein synthesis; AlphaScreen technology; Protein-protein interaction inhibitors;
The N-terminal helix α0 of hepatitis C virus NS3 protein dictates the subcellular localization and stability of NS3/NS4A complex
Keywords: HCV; NS3; Helix α0; Membrane association; Protein degradation;
Characterisation of interaction between NS3 and NS5B protein of classical swine fever virus by deletion of terminal sequences of NS5B
Keywords: Classical swine fever virus; NS5B; NS3; NS3-NS5B interaction;
Research ArticleIron inhibits replication of infectious hepatitis C virus in permissive Huh7.5.1 cells
Keywords: HCV; hepatitis C virus; SIH; salicylaldehyde isonicotinoyl hydrazone; NS3; non-structural protein 3; CHC; chronic hepatitis C; TfR1; transferrin receptor 1; PBS; phosphate-buffered saline; RT-PCR; reverse-transcription polymerase chain reaction; Hmox1; he