Keywords: عامل هسته سلول های فعال شده فعال است; SL; sarcolemma; SR; saroplasmic reticulum; SERCA; sarcoplasmic/endoplasmic reticulum calcium ATPase; NCX; Na+/Ca2+ exchanger; EC; excitation-contraction; AP; action potential; LCC; L-type calcium channel; HIP; human amylin transgenic; NFAT; nuclear fact
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Keywords: عامل هسته سلول های فعال شده فعال است; ALP; alkaline phosphatase; BMPs; bone morphogenetic proteins; C/EBPÃ; CCAAT/enhancer binding protein beta; CIA; collagen II induced arthritis; CTD; C-terminal domain; Cx43; connexin43; Cxs; connexins; DMOADs; disease-modifying osteoarthritis drugs; ECM;
Keywords: عامل هسته سلول های فعال شده فعال است; AANAT; arylalkylamine N-acetyltransferase; AE2; Clâ/HCO3- anion exchanger 2; ANIT; α-naphthylisothiocyanate; BA; biliary atresia; BDL; bile duct ligation; cAMP; adenosine 3â²,5â²-cyclic monophosphate; CCA; cholangiocarcinoma; CCl4; carbon tetrachlo
Keywords: عامل هسته سلول های فعال شده فعال است; Atherosclerosis; Cardiovascular diseases; Cell cycle; Proliferation; Pulmonary hypertension; Restenosis; Signaling pathway; Vascular smooth muscle cells; ACE; angiotensin converting enzyme; aFGF; acidic FGF; Ang II; angiotensin II; AP-1; activating protei
Keywords: عامل هسته سلول های فعال شده فعال است; AngII; angiotensin II; CKD; chronic kidney disease; EGF; epidermal growth factor; FGF; fibroblast growth factor; FGFR; fibroblast growth factor receptor; FRS2α; FGF receptor substrate 2α; HPG; heparan sulfate proteoglycans; IGF-1; insulin-like growth fa
Keywords: عامل هسته سلول های فعال شده فعال است; Ca2+ channel; K+ channel; Ca2+-activated Clâ channel; Transcription; Pre-mRNA splicing; Protein degradation; AD; Alzheimer's disease; ADPR; ADP ribose; AITC; allyl isothiocyanate; AKAP; A-kinase anchoring protein; AMPK; 5â² AMP-activated protein kinase
Keywords: عامل هسته سلول های فعال شده فعال است; Epigenetic dynamics; Immune system; Autoimmune diseases; DNA methylation; Histone modifications; DNMT; DNA methyltransferase; TET; ten-eleven translocation; AID/AICDA; activation-induced cytidine deaminase; APOBEC; Apolipoprotein B mRNA editing enzyme; BE
Keywords: عامل هسته سلول های فعال شده فعال است; DAMP; danger-associated molecular pattern; GWAS; genome-wide association studies; IL; interleukin; iNOS; inducible nitric oxide synthase; iTreg; inflammatory suppressing inducible regulatory T cells; LPS; lipopolysaccharide; MHC; major histocompatibility;
The effect of brain-derived neurotrophic factor on radiation-induced neuron architecture impairment is associated with the NFATc4/3 pathway
Keywords: عامل هسته سلول های فعال شده فعال است; NFAT; nuclear factor of activated T-cells; BDNF; brain-derived neurotrophic factor; NS; normal saline; SD; Sprague-Dawley; WBI; whole brain irradiation; GFP; green fluorescent protein; DAPI; 4,6-diamidino-2-phenylindole; ROIs; regions of interest, CsA,
Cyclosporin A indirectly attenuates activation of group 2 innate lymphoid cells in papain-induced lung inflammation
Keywords: عامل هسته سلول های فعال شده فعال است; BAL; bronchoalveolar lavage; CsA; cyclosporin A; ICOS; inducible T cell costimulator; ICOSL; inducible T cell costimulator ligand; ILC2s; group 2 innate lymphoid cells; NFAT; nuclear factor of activated T-cells; Th2; type 2 helper T; TSLP; thymic stromal
Role of SOCE architects STIM and Orai proteins in Cell Death
Keywords: عامل هسته سلول های فعال شده فعال است; SOCE; store operated Ca2+ entry; STIM1/2; stromal interaction molecule 1/2; NFAT; nuclear factor of activated T-cells; IP3; inositol trisphosphate; ARC; arachidonic acid-regulated channels; LRC; leukotriene C4-regulated channels; PKB; protein kinase B; PK
Anandamide inhibits FcεRI-dependent degranulation and cytokine synthesis in mast cells through CB2 and GPR55 receptor activation. Possible involvement of CB2-GPR55 heteromers
Keywords: عامل هسته سلول های فعال شده فعال است; AEA; anandamide; BMMCs; bone marrow-derived mast cells; FcεRI; high affinity IgE receptor; 2-AG; 2-arachidonoylglycerol; DNP-HSA; dinitrophenol coupled to human serum albumin (antigen); IgE; immunoglobulin E; TNF; Tumor Necrosis Factor; IL; interleukin;
Anti-inflammatory effects of luteolin: A review of in vitro, in vivo, and in silico studies
Keywords: عامل هسته سلول های فعال شده فعال است; NF-κB; nuclear factor kappa B; AP-1; activator protein; STAT3; signal transducer and activator of transcription 3; NK cells; natural killer cells; TNF-α; tumor necrosis factor-α; NO; nitric oxide; iNOS; inducible nitric oxygen synthase; ROS; reactive o
Anti-angiogenic effects of Qingdu granule on breast cancer through inhibiting NFAT signaling pathway
Keywords: عامل هسته سلول های فعال شده فعال است; saikosaponins a (PubChem CID:167928); saikosaponins d (PubChem CID: 107793); hesperidin (PubChem CID:10621); rutin (PubChem CID: 5280805); Qingdu granule; Breast cancer; Angiogenesis; Nuclear factor of activated T-cells;
Regulation of proto-oncogene Orai3 by miR18a/b and miR34a
Keywords: عامل هسته سلول های فعال شده فعال است; SOCE; store operated Ca2+ entry; STIM1/2; stromal interaction molecule 1/2; miRs; micro-RNAs; 3â²UTR; 3â²Un-translated region; 2-APB; 2-aminoethoxydiphenyl borate; ER+; estrogen receptor positive; NFAT; nuclear factor of activated T-cells; Orai3; SOCE;
WNT receptor signalling in lung physiology and pathology
Keywords: عامل هسته سلول های فعال شده فعال است; ABC; active β-catenin/non-phosphorylated β-catenin; APC; adenomatous polyposis coli; ATI; alveolar epithelial type I cell; ATII; alveolar epithelial type II cell; AXIN; axis inhibition protein; CBR2; carbonyl reductase 2; CK1; casein kinase 1; CELSR1; c
MicroRNA-34a targets regulator of calcineurin 1 to modulate endothelial inflammation after fetal cardiac bypass in goat placenta
Keywords: عامل هسته سلول های فعال شده فعال است; MicroRNAs; Placental insufficiency; Endothelial cells; Inflammation; Fetus; Cardiopulmonary bypass; miRNA; microRNA; miR-34a; miRNA-34a; mRNA; messenger RNA; 3'-untranslated regions (UTRs); untranslated region; RCAN1; regulator of calcineurin 1; NFATC1;
Water extract of Uncaria sinensis suppresses RANKL-induced bone loss by attenuating osteoclast differentiation and bone resorption
Keywords: عامل هسته سلول های فعال شده فعال است; Uncaria sinensis; Osteoclasts; Receptor activator for nuclear factor-κB ligand; Nuclear factor of activated T-cells; Cytoplasmic 1;
Multiple pathways of SIRT6 at the crossroads in the control of longevity, cancer, and cardiovascular diseases
Keywords: عامل هسته سلول های فعال شده فعال است; ALP; alkaline phosphatase; AMPK; AMP-activated protein kinase; Ang II; angiotensin II; BER; base excision repair; cAMP; cyclic adenosine monophosphate; CDK; cyclin-dependent kinase; CHIP; carboxyl terminus of Hsp70-interacting protein; CLL; chronic lympho
Integrin linked kinase regulates the transcription of AQP2 by NFATC3
Keywords: عامل هسته سلول های فعال شده فعال است; AQP2; Aquaporin-2; AP-1; Activator protein-1; b.w.; Body weight; CH2O; Free H2O clearance; cKD-ILK; ILK conditional-knockdown mice; Cn; Calcineurin; Col I; Calf skin collagen type I; Cosm; Osmolar clearance; CRE; BALB/cJ mice carrying a CMV-driven tamoxif
Dual signaling evoked by oxidized LDLs in vascular cells
Keywords: عامل هسته سلول های فعال شده فعال است; AAPH; 2,2'-azobis(2-amidinopropane) dihydrochloride; AIF; apoptotic inducing factor; AMVN; 2,4-dimethylvaleronitrile; AP-1; activator protein 1; ATF6; activating transcription factor 6; CDE; clathrin-dependent endocytosis; CCL2; chemokine ligand 2 (or MCP
BRET-based β-arrestin2 recruitment to the histamine H1 receptor for investigating antihistamine binding kinetics
Keywords: عامل هسته سلول های فعال شده فعال است; H1R; histamine H1 receptor; GPCR; G protein-coupled receptor; NFAT; nuclear factor of activated T-cells; ERK; extracellular signal-regulated kinases; BRET; bioluminescence resonance energy transfer; HEK293T; Human embryonic kidney cells transformed with l
Anti-TNF-α and anti-arthritic effect of patuletin: A rare flavonoid from Tagetes patula
Keywords: عامل هسته سلول های فعال شده فعال است; RA; rheumatoid arthritis; TNF; tumor necrosis factor; NO; nitric oxide; IL; interleukin; ROS; reactive oxygen species; AIA; adjuvant induced arthritis; MMP; matrix metalloproteinase; PMNs; polymorphonuclear cells; PO; peroxide; RF; rheumatoid factor; SD;
Alteration of canonical and non-canonical WNT-signaling by crystalline silica in human lung epithelial cells
Keywords: عامل هسته سلول های فعال شده فعال است; ACTA2; Actin, alpha, smooth muscle; ANGPTL4; Angiopoietin-like 4; ANOVA; Analysis of variance; AXIN; Axis inhibition protein; BMP; Bone morphogenic protein; BMPR1B; BMP receptor 1B; CACNA2D3; Calcium channel, voltage-dependent, alpha 2/delta subunit 3; CC
Signaling in dopamine D2 receptor-oxytocin receptor heterocomplexes and its relevance for the anxiolytic effects of dopamine and oxytocin interactions in the amygdala of the rat
Keywords: عامل هسته سلول های فعال شده فعال است; Anxiety; Fear; Amygdala; Dopamine D2 receptor; Oxytocin receptor; Receptor-receptor interactions; Raclopride; Oxytocin; Heteroreceptor complexes; AC; adenylyl cyclase; BLA; basolateral complex; ADAR; adenosine A receptor; CAS; castor transcription factor;
Peroxiredoxin 5 (Prx5) decreases LPS-induced microglial activation through regulation of Ca2+/calcineurin-Drp1-dependent mitochondrial fission
Keywords: عامل هسته سلول های فعال شده فعال است; TLR4; Toll-like receptor 4; NADPH oxidase; nicotinamide adenine dinucleotide phosphate oxidase; Cys; cysteine; Drp1; dynamin-related protein 1; Fis1; mitochondrial fission 1; Mfn1/2; mitofusin 1 and 2; Opa1; optic atrophy protein 1; Ser; serine; cAMP; Cyc
Astrocytes in physiological aging and Alzheimer's disease
Keywords: عامل هسته سلول های فعال شده فعال است; 3xTg-AD; triple transgenic mice model of Alzheimer's disease; AD; Alzheimer's disease; APP; amyloid precursor protein; ATP; adenosine triphosphate; CA1; Cornu Ammonis 1; CNS; Central nervous system; DG; dentate gyrus; GABA; γ-aminobutyric acid; GFAP;
Epidermal growth factor receptor inhibitor cancer drug gefitinib modulates cell growth and differentiation of acute myeloid leukemia cells via histamine receptors
Keywords: عامل هسته سلول های فعال شده فعال است; 4-MH; 4-methylhistamine; AML; acute myelogenous leukemia; CML; chronic myelogenous leukemia; cAMP; cyclic adenosine monophosphate; CRE; cAMP response element; EGFR; epidermal growth factor receptor; ER; estrogen receptor alpha; FSK; Forskolin; GPCR; G-pro
Multifaceted plasma membrane Ca2Â + pumps: From structure to intracellular Ca2Â + handling and cancer
Keywords: عامل هسته سلول های فعال شده فعال است; CaM; calmodulin; CBS; calmodulin-binding sequence; ER; endoplasmic reticulum; ERK; extracellular signal-regulated kinase; HDAC; histone deacetylase; HUVEC; human umbilical vein endothelial cells; IP3; inositol-1,4,5-trisphosphate; MLEC; mouse lung endothe
Toll-like receptor-3 mediates HIV-1 transactivation via NFκB and JNK pathways and histone acetylation, but prolonged activation suppresses Tat and HIV-1 replication
Keywords: عامل هسته سلول های فعال شده فعال است; TLR3; HIV; Viral transactivation; LTR; NFκB; JNK; STAT1; Histone acetylation; Epigenetics; Human monocyte-derived macrophages; TZM-bl; U38 cells; AP-1; activator protein-1; B2M; beta-2-microglobulin; BCA; bicinchoninic acid; CAT; chloramphenicol acetyltr
Isoflurane induced cognitive impairment in aged rats through hippocampal calcineurin/NFAT signaling
Keywords: عامل هسته سلول های فعال شده فعال است; Calcineurin; Nuclear factor of activated T-cells; Isoflurane; Cyclosporine A; Cognitive impairment
Zinc-binding metallothioneins are key modulators of IL-4 production by basophils
Keywords: عامل هسته سلول های فعال شده فعال است; BMBA; bone marrow-derived basophil; Ca; calcium; CaN; calcineurin; CsA; cyclosporin A; FcÉRI; Fc epsilon receptor 1; MT; metallothionein; NFAT; nuclear factor of activated T-cells; PI3K; phosphoinositide 3-kinase; PKC; protein kinase C; siRNA; short inte
A robust and scalable TCR-based reporter cell assay to measure HIV-1 Nef-mediated T cell immune evasion
Keywords: عامل هسته سلول های فعال شده فعال است; TCR; T-cell receptor; CTL; Cytotoxic T lymphocyte; NFAT; Nuclear factor of activated T-cells; HIV; Human immunodeficiency virus; Nef; Negative regulatory factor; Human immunodeficiency virus; Nef; HLA class I; Immune evasion; T cell receptor;
Embryonal Fyn-associated substrate (EFS) and CASS4: The lesser-known CAS protein family members
Keywords: عامل هسته سلول های فعال شده فعال است; 5-HT; 5-hydroxytryptamine, serotonin; A549; non-small cell lung cancer cell line; AD; Alzheimer's disease; ADPKD; autosomal dominant polycystic kidney disease; Aire; autoimmune regulator; AP-1; activator protein 1; APP; amyloid precursor protein; AREB6; Z
STIM1 elevation in the heart results in aberrant Ca2Â + handling and cardiomyopathy
Keywords: عامل هسته سلول های فعال شده فعال است; AngII; angiotensin II; BDM; 2,3-butanedione monoxime; CaMKII; Ca2Â +/calmodulin-dependent protein kinase II; CMF; Ca2Â +- and Mg2Â +-free Ringer's solution; CPA; cyclopiazonic acid; EC; excitation-contraction; ER; endoplasmic reticulum; LTCC; L-type Ca2
Genetic or pharmacologic disruption of the calcineurin-nuclear factor of activated T-cells axis prevents social stress-induced voiding dysfunction in a murine model
Keywords: عامل هسته سلول های فعال شده فعال است; Social stress; Voiding dysfunction; Barrington's nucleus; Nuclear factor of activated T-cells; Corticotropin releasing factorNFAT, nuclear factor of activated T cells; CsA, cyclosporine; KO, knockout; WT, wild-type; BN, Barrington's nucleus; CRF, corticot
Activation of TRPV1 mediates thymic stromal lymphopoietin release via the Ca2+/NFAT pathway in airway epithelial cells
Keywords: عامل هسته سلول های فعال شده فعال است; TRP channel; Transient receptor potential vanilloid 1; Protease-activated receptor-2; Thymic stromal lymphopoietin; Asthma; Nuclear factor of activated T-cells;
Inhibitory activity on RANKL-mediated osteoclastogenesis of Glossogyne tenuifolia extract
Keywords: عامل هسته سلول های فعال شده فعال است; EA; ethyl acetate; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylene glycol tetraacetic acid; FBS; fetal bovine serum; GT; Glossogyne tenuifolia; GTE; Glossogyne tenuifolia ethanolic extract; IGEPAL; tert-octylphenoxy poly(oxyethylene)ethanol; JNK; c-
P21-activated kinase in inflammatory and cardiovascular disease
Keywords: عامل هسته سلول های فعال شده فعال است; AID; Auto-inhibitory domain; ATP; Adenosine-triphosphate; B-cell; B lymphocytes; BLNK; B cell linker protein; CaM; Calmodulin; Cdc; Cell division control protein; cyt b558; Flavocytochrome b558; DUOX1/2; Dual oxidase 1/2; EF hand motif; Helix-loop-helix s
A close look at brain dynamics: Cells and vessels seen by in vivo two-photon microscopy
Keywords: عامل هسته سلول های فعال شده فعال است; 2-PM; two-photon microscopy; APC; antigen presenting cell; BBB; blood-brain barrier; ChABC; bacterial enzyme chondroitinase ABC; CNS; central nervous system; EAE; experimental autoimmune encephalopathy; EATs; erythrocyte-associated transients; ECM; extr
Crosstalk between mitogen-activated protein kinases and mitochondria in cardiac diseases: Therapeutic perspectives
Keywords: عامل هسته سلول های فعال شده فعال است; Heart; MAPK; Cardiac diseases; Mitochondria; Cell signaling; AngII; angiotensin II; CA; constitutively active; CHIP; C terminus of Hsc70-interacting protein; CT-1; cardiotrophin-1; ÎΨmit; mitochondrial membrane potential; DN; dominant negative; ERK1/2;
Trisomy of the Dscr1 gene suppresses early progression of pancreatic intraepithelial neoplasia driven by oncogenic Kras
Keywords: عامل هسته سلول های فعال شده فعال است; Dscr1; Down syndrome critical region-1; NFAT; nuclear factor of activated T-cells; PanIN; pancreatic intraepithelial neoplasia; PDA; pancreatic ductal adenocarcinoma; Dyrk1a; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A; CK-19; cytoke
EDF-1 downregulates the CaM/Cn/NFAT signaling pathway during adipogenesis
Keywords: عامل هسته سلول های فعال شده فعال است; Cn; calcineurin; CaM; calmodulin; CsA; cyclosporine A; Dex; dexamethasone; EDF-1; endothelial differentiation factor-1; Iono; ionomycin; NFAT; nuclear factor of activated T-cells; St; staurosporine; Differentiation; Adipogenesis; edf1; Calmodulin; Calcine
Glycyrrhizic acid and 18β-glycyrrhetinic acid recover glucocorticoid resistance via PI3K-induced AP1, CRE and NFAT activation
Keywords: عامل هسته سلول های فعال شده فعال است; Glycyrrhizic acid; 18β-Glycyrrhetinic acid; Glucocorticoid receptor; Phosphoinositide 3-kinase; Glucocorticoid resistance; 18βGA; 18β-glycyrrhetinic acid; Akt; protein kinase B; AP1; activator protein 1; COPD; chronic obstructive pulmonary disease; CRE
Aplotaxene blocks T cell activation by modulation of protein kinase C-θ-dependent pathway
Keywords: عامل هسته سلول های فعال شده فعال است; Aplotaxene; Immunosuppression; IL-2; T cell activation; Protein kinase C-θ; AP-1; activator protein 1; ERK; Extracellular signal-regulated kinase; JNK; c-Jun N-terminal kinase; LFA-1; Lymphocyte function-associated antigen 1; MAPK; Mitogen-activated prot
Nuclear factor of activated T-cells 1 increases sensitivity of v-myb transformed monoblasts to all-trans retinoic acid
Keywords: عامل هسته سلول های فعال شده فعال است; BM2wt; BM2 wild type cells; BM2NFAT1; BM2 cells transfected with the pEGFP.N1-NFAT1 plasmid; BM2VIVIT; BM2 cells transfected with the pEGFP.N1-VIVIT plasmid; BM2mock; BM2 cells transfected with the pEGFP.N1 plasmid; ATRA; all-trans retinoic acid; CDK4; cy
Genetic analysis of an enhancer of the NKX2-5 gene in ventricular septal defects
Keywords: عامل هسته سلول های فعال شده فعال است; CHD; congenital heart diseases; VSD; ventricular septal defects; GATA4; GATA transcription factor 4; TBX5; T-box transcription factor 5; TBX20; T-box transcription factor 20; NKX2-5; NK2 transcription factor, locus 2; MEF2C; myocyte-specific enhancer fact
Calcium regulates caveolin-1 expression at the transcriptional level
Keywords: عامل هسته سلول های فعال شده فعال است; Cacna1; L-type calcium channel alpha-1 subunit (c, etc.); HBSS; Hank's buffered salt solution; NFAT; nuclear factor of activated T-cells; PI; propidium iodide; qPCR; quantitative real-time PCR; RT-PCR; reverse transcriptase-polymerase chain reaction; St
Myocyte enhancer factor 2 (MEF2) tethering to muscle selective A-kinase anchoring protein (mAKAP) is necessary for myogenic differentiation
Keywords: عامل هسته سلول های فعال شده فعال است; mAKAP; muscle specific A-kinase anchoring protein; MEF2; myocyte enhancer factor 2; PKA; protein kinase A; PDE4D3; phosphodiesterases type 4D3; ERK5; big mitogen-activated protein kinase; GFP; green fluorescent protein; NFAT; nuclear factor of activated T
Vav1 in differentiation of tumoral promyelocytes
Keywords: عامل هسته سلول های فعال شده فعال است; GEF; guanosine exchange factor; APL; acute promyelocytic leukemia; ATRA; All-trans retinoic acid; LIC; leukemia initiating cells; PMA; phorbol 12-myristate 13-acetate; PIP; phosphatidylinositol 4-phosphate; PIP2; phosphatidylinositol 4, 5-bisphosphate; PI