دانلود مقالات ISI درباره Pdk + ترجمه فارسی

بربرین کاهش تولید گلوکز کبدی مبتنی بر پریووت با محدود کردن واردات پیوروتوی میتوکندری از حامل پیوروتین میتوکندری 1

Berberine Reduces Pyruvate-driven Hepatic Glucose Production by Limiting Mitochondrial Import of Pyruvate through Mitochondrial Pyruvate Carrier 1

Keywords: AMPK; AMP-activated protein kinase; DCA; Dichloroacetate; FACD; Fatty acyl CoA dehydrogenase; G-6-Pase; Glucose-6-phosphatase; HFD; High-fat diet; HGP; Hepatic glucose production; KCT; β-ketoacyl CoA thiolase; LDH; Lactate dehydrogenase; MPC; Mitochondri

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

پروتئین های جدا سازی شده به عنوان یک هدف درمانی برای محافظت از قلب دیابتی

Uncoupling proteins as a therapeutic target to protect the diabetic heart

Keywords: ACC; acetyl-CoA carboxylase; ACE; angiotensin-converting enzyme; AICAR; 5-aminoimidazole-4-carboxamide ribonucleotide; ALDH2; aldehyde dehydrogenase 2; AMPK; 5' AMP-activated protein kinase; ATP; adenosine triphosphate; Bax; Bcl-2-like protein 4; BNIP3; B

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2018 سفارش ترجمه

روند فعلی برای درک متابولیسم لیپیدها در دیاتومه

Current trends to comprehend lipid metabolism in diatoms

Keywords: Docosahexaenoic acid; Eicosapentaenoic acid; Lipid droplets; Phaeodactylum tricornutum; Polyunsaturated fatty acid; Triacylglycerol; ACCase; acetyl-CoA carboxylase; ACP; acyl carrier protein; ALA; α-linolenic acid; ATS1; plastidic glycerol-3-phosphate ac

دانلود رایگان متن کامل مقاله ISI 65 صفحه سال انتشار : 2018 سفارش ترجمه

مکانیزم های انعقاد انقباض عضلات صاف عروق برجسته اهداف کلیدی در بیماری های عروقی

Evolving mechanisms of vascular smooth muscle contraction highlight key targets in vascular disease

Keywords: AGE; Advanced Glycation End products; ALDH2; aldehyde dehydrogenase 2; AngII; angiotensin II; BKCa; large conductance Ca2+-activated K+ channel; Ca2+; calcium; [Ca2+]c; cytosolic free Ca2+ concentration; CaD; caldesmon, CaM, calmodulin; cAMP; cyclic adeno

دانلود رایگان متن کامل مقاله ISI 103 صفحه سال انتشار : 2018 سفارش ترجمه

آموزش مبانی متابولیسم سرطان: ایجاد استراتژی های ضد توموری با بهره گیری از تفاوت های متابولیسم سلول های طبیعی و سلولی

Teaching the basics of cancer metabolism: Developing antitumor strategies by exploiting the differences between normal and cancer cell metabolism

Keywords: ATP; adenosine triphosphate; BrP; bromopyruvate; CO2; carbon dioxide; CoA; acetyl-coenzyme A; 2-DG; 2-deoxyglucose; ETC; electron transport chain; FAO; fatty acid oxidation; FAD; flavin adenine dinucleotide; FDG; fluorinated deoxyglucose; FFA; free fatty

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

برنامه ریزی متابولیسم مرکزی کربن در سلول های بنیادی سرطانی

Reprogramming of central carbon metabolism in cancer stem cells

Keywords: 2-DG; 2-deoxyglucose; 2-HG; 2-hydroxyglutarate; 5mC; 5-methlycystosine; ACACA; acetyl-CoA carboxylase; AML; acute myeloid leukemia; AMPK; adenosine monophosphate-activated protein kinase; ATP; adenosine triphosphate; ALDH; aldehyde dehydrogenase; ADCs; an

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

ارزیابی ویژگی های مهار کننده کم اکسامات، آمینوسی سکته و دی کروآل آ آتا بر متابولیسم انرژی سرطان

Assessment of the low inhibitory specificity of oxamate, aminooxyacetate and dichloroacetate on cancer energy metabolism

Keywords: AAT; aspartate aminotransferase; Ala; alanine; AlaT; alanine aminotransferase; ALD; aldolase; AOA; aminooxyacetate; Asp; aspartate; CS; citrate synthase; 2-DOG; 2-deoxyglucose; DCA; dichloroacetate; DHAP; dihydroxyacetone phosphate; ENO; enolase; Ery4P; e

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2017 سفارش ترجمه

حمل و نقل هالوکسیدها در غشاء بیولوژیک

Transport of haloacids across biological membranes

Keywords: 2,2DCPA; 2,2-dichloropropionate; 2MCPA; 2-monochloropropionic acid; 3-BrPA; 3-bromopyruvic acid; 5-FU; 5-fluorouracil; Bcc; Burkholderia cepacia complex; CCCP; carbonyl cyanide m-chlorophenyl hydrazine; DBA; dibromoacetic acid; DCA; dichloroacetic acid; F

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

اکسستریل و مکانیسم های سیگنالینگ بقا

Oxysterols and mechanisms of survival signaling

Keywords: Oxysterols; Survival; Nrf2; Autophagy; 5,6-S; 5,6-secosterol; 24OH; 24-hydroxycholesterol; 25OH; 25-hydroxycholesterol; 27OH; 27-hydroxycholesterol; 7K; 7-ketocholesterol; 7βOH; 7β-hydroxycholesterol; AGE; advanced glycation end products; AMPK; AMP-acti

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

مسیر گلیکولیتی بر تمایز تک سلولی انسان به ماکروفاژهای نظارتی اثر می گذارد

Glycolytic pathway affects differentiation of human monocytes to regulatory macrophages

Keywords: M-CSF; macrophage colony-stimulating factor; IFN-γ; interferon-gamma; M-Mϕ; macrophage differentiated from CD14 positive monocytes in the presence of M-CSF; Mγ-Mϕ; macrophage differentiated from CD14 positive monocytes in the presence of M-CSF and IFN

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2016 سفارش ترجمه

میتوکندری در زیست شناسی سلول های بنیادی مزانشیمی و سلول درمان: از تمایز سلولی به انتقال میتوکندری

Mitochondria in mesenchymal stem cell biology and cell therapy: From cellular differentiation to mitochondrial transfer

Keywords: AMPK; AMP-activated protein kinase; BM; bone marrow; CAT; catalase; Complex I; NADH-coenzyme Q oxidoreductase; Complex II; succinate-coenzyme Q oxidoreductase; Complex III; ubiquinol-cytochrome c oxidoreductase; COX; cytochrome c oxidase; Complex V; FoF1A

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2016 سفارش ترجمه

بیان پیرووات دهیدروژناز کیناز و تغییرات متابولیک پس از قرار گرفتن در معرض دیکلوآلاناز در سلول های سرطانی سرطان کولورکتال انسان

Pyruvate dehydrogenase kinase expression and metabolic changes following dichloroacetate exposure in anoxic human colorectal cancer cells

Keywords: CRC; colorectal cancer; DCA; dichloroacetate; PDH; pyruvate dehydrogenase; PDK; pyruvate dehydrogenase kinase; MA; mitochondrial activity.; Dichloroacetate; Pyruvate dehydrogenase kinase; Anoxia; Mitochondrial function; Colorectal cancer;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

تجویز بیرونی اسپرم باعث بهبود استفاده از گلوکز و کاهش وزن در موش می شود

Exogenous administration of spermine improves glucose utilization and decreases bodyweight in mice

Keywords: ACC; Acetyl CoA carboxylase; AMP; Adenosine monophosphate; AMPK; 5׳AMP activated protein kinase; AUC; Area under the curve; CPT; Carnitine palmitoyl transferase; FFA; Free fatty acids; HFD; High fat diet; PDK; Pyruvate dehydrogenase kinase; SSAT; Spermid

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

قاچاق محرک گیرنده توسط لیگاند

Ligand-directed trafficking of receptor stimulus

Keywords: AC; adenylate cyclase; β-AR; β-adrenergic receptor; CaM; calmoduline; cAMP; cyclic adenosine monophosphate; CHO; Chinese hamster ovary; EGFR; epidermal growth factor receptor; ERK; extracellular signal-regulated kinase; DAG; diacylglycerol; DR; dopamine

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

تنظیم متابولیسم انرژی توسط اسیدهای چرب طولانی مدت

Regulation of energy metabolism by long-chain fatty acids

Keywords: ACAA2; 3-oxoacyl-CoA thiolase; ADIPOR; adiponectin receptor; AF1,2; activation function 1,2; AMPK; AMP-activated protein kinase; ATF4; activating transcription factor 4; ATGL; adipose triglyceride lipase; CaMK; calcium/calmodulin-dependent kinase; CD36; f

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2014 سفارش ترجمه

نقش بالقوه و منافع درمانی مایوآنزیتول در بیماریهای متابولیکی

Potential role and therapeutic interests of myo-inositol in metabolic diseases

Keywords: Inositol; Insulin resistance; Diabetes; Polycystic ovary syndrome; Metabolic syndrome; Diabetic neuropathy; AC; adenylyl cyclase; ACC; acetyl-coenzyme A carboxylase; AGEs; advanced glycation end products; AMP; adenosine monophosphate; cAMP; cyclic AMP; AM

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

مسیرهای مولکولی آنوکیک و نقش آن در پیشرفت سرطان

Anoikis molecular pathways and its role in cancer progression

Keywords: AMPK; AMP activated protein kinase; ECM; extracellular matrix; EGFR; epidermal growth factor receptor; EMT; epithelial-mesenchymal transition; ERK; extracellular signal-regulated kinase; FLIP; FLICE inhibitory protein; FAK; focal adhesion kinase; GSK-3;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2013 سفارش ترجمه

Melanoma metabolism contributes to the cellular responses to MAPK/ERK pathway inhibitors

Keywords: MAPK; mitogen-activated protein kinase; BRAF; v-raf murine sarcoma viral oncogene homolog B1; MEK; mitogen-activated protein/extracellular signal- regulated kinase kinase; ERK; extracellular signal-regulated kinase; HIF-1α; hypoxia inducible factor 1 alp

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Novel approaches in the treatment of diabetic cardiomyopathy

Keywords: ACE; angiotensin convertase enzyme; ACEi; angiotensin convertase enzyme inhibitor; ADP; adenosine di phosphate; AGE; advanced glycation end products; AM; adrenomedullin; AMP; adenosine mono phosphate; ARB; angiotensin receptor blocker; ATP; adenosine tri

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Integrated circuit technology characterization and evaluation using automated CAD tool

Keywords: Device characterization; Automation; CAD; SKILL script; OCEAN script; PDK;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Anticancer effects of some novel dichloroacetophenones through the inhibition of pyruvate dehydrogenase kinase 1

Keywords: PDK; pyruvate dehydrogenase kinase; PDC; pyruvate dehydrogenase complex; MMP; mitochondrial membrane potential; ROS; reactive oxygen species; OXPHOS; oxidative phosphorylation; TCA; tricarboxylic acid; PDPs; pyruvate dehydrogenase phosphatases; DCA; dichl

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Design and characterization of α-lipoic acyl shikonin ester twin drugs as tubulin and PDK1 dual inhibitors

Keywords: Cancer; Shikonin; Twin drug; Pyruvate dehydrogenase kinase; Tubulin; CADD; computer assistant drug design; NOS; nitric oxide synthase; PKM2; pyruvate kinase isozymes M2; GLUT1; Glucose transporter 1; LA; alpha-lipoic acid; PDH; pyruvate dehydrogenase; PDC

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

The mechanism of tumour cell death by metal-based anticancer drugs is not only a matter of DNA interactions

Keywords: 15-LOX-1; 15-lipoxygenase; AIF; apoptosis inducing factor; APC; adenomatous polyposis coli; AKT or PKB; protein kinase B; ATG16L2; autophagy related 16 like 2; AUC; area under the curve; Bad; Bcl-2 associated death promoter; Bcl-2; B-cell lymphoma 2; Bcl-

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2018 سفارش ترجمه

Transcriptomic analysis of Momordica charantia polysaccharide on streptozotocin-induced diabetic rats

Keywords: M. charantia; Momordica charantia; RNA-seq; RNA sequencing; T2DM; Type 2 diabetes mellitus; IR; insulin resistance; PPAR; peroxisome proliferator-activated receptor; FBG; fasting blood glucose; G6Pase; glucose-6-phosphatase; PEPCK; phosphoenol pyruvate ca

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

The FOXO3-FOXM1 axis: A key cancer drug target and a modulator of cancer drug resistance

Keywords: ABCB1; ATP-binding cassette sub-family B member 1; AML; acute myeloid leukaemia; AMPK; adenosine monophosphate-activated protein kinase; ATM; Ataxia-telangiectasia mutated; AURKA; aurora kinase A; BER; base excision repair; Bim; B-cell lymphoma 2 interact

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Mitochondrial hyperpolarization in iPSC-derived neurons from patients of FTDP-17 with 10+16 MAPT mutation leads to oxidative stress and neurodegeneration

Keywords: 2-NBDG; 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose; AD; Alzheimer's disease; CBD; Corticobasal Degeneration; CSF; Cerebrospinal Fluid; DHE; Dihydroethidium; ETC; Electron Transport Chain; FCCP; Carbonyl cyanide-4-(trifluoromethoxy)pheny

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Circadian Clock Is Involved in Regulation of Hepatobiliary Transport Mediated by Multidrug Resistance-Associated Protein 2

Keywords: ABC transporters; P-glycoprotein; multidrug resistance-associated proteins; pharmacokinetics; biliary excretion; ABC; ATP-binding cassette; Bcrp; breast cancer resistance protein; BMAL1; brain and muscle arnt-like protein-1; CLOCK; circadian locomotor out

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

Indazole-based ligands for estrogen-related receptor α as potential anti-diabetic agents

Keywords: Estrogen-related receptor α; ERRα; Nuclear receptor; Anti-diabetic; Metabolic syndrome; Indazole; Thiazolidenedione; TZD; Insulin resistance; ERR; estrogen-related receptor; ER; estrogen receptor; ERE; estrogen response element; ERRE; estrogen-related r

دانلود رایگان متن کامل مقاله ISI 73 صفحه سال انتشار : 2017 سفارش ترجمه

Molecular characterization and functional analysis of BdFoxO gene in the oriental fruit fly, Bactrocera dorsalis (Diptera: Tephritidae)

Keywords: TOR; target of rapamycin; JNK; Jun NH2-terminal kinase; FoxO; forkhead box O; InR; insulin receptor; Akt; protein kinase B; PI3K; phosphatidylinositol 3-kinase; 4EBP; 4E binding protein; ILPs; insulin-like peptides; RT-qPCR; reverse transcription-quantita

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

GSTZ1 expression and chloride concentrations modulate sensitivity of cancer cells to dichloroacetate

Keywords: [Cl−]; chloride concentration; DCA; dichloroacetate; ERK; extracellular signal-regulated kinase; GSTZ1; glutathione transferase Z1; HER2; human epidermal growth factor receptor 2; PDC; pyruvate dehydrogenase complex; PDK; pyruvate dehydrogenase kinase;

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2016 سفارش ترجمه

Threonine 34 phosphorylation by phosphoinositide-dependent protein kinase 1 facilitates dissociation of Akt from the plasma membrane

Keywords: Akt; protein kinase B; IGF; insulin-like growth factor; KD; kinase domain; MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2; MS; mass spectrometry; PDK; phosphoinositide-dependent protein kinase; PH; pleckstrin homology; PIK3; phospha

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Profiling metabolic remodeling in PP2Acα deficiency and chronic pressure overload mouse hearts

Keywords: ACADM; acyl‐coenzyme A dehydrogenase, middle chain (C4-C12); ACADS; acyl‐coenzyme A dehydrogenase, short chain (C4-C8); ACADVL; acyl‐coenzyme A dehydrogenase, very long chain; ACSL1; acyl‐CoA synthetase long‐chain family member 1; ANP; atria

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Redox regulation of metabolic and signaling pathways by thioredoxin and glutaredoxin in NOS-3 overexpressing hepatoblastoma cells

Keywords: ACO; aconitase; ASK1; apoptosis signal-regulating kinase 1; Bcl-2; B-cell lymphoma 2; CaM; calmodulin; CD95; cluster of differentiation 95; DTNB; 5,5-dithio-bis-2-nitrobenzoic acid; ELISA; enzyme-linked immunosorbent assay; GAPDH; glyceraldehyde-3-phospha

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

A novel effect of DMOG on cell metabolism: direct inhibition of mitochondrial function precedes HIF target gene expression

Keywords: α-KG; α-ketoglutarate; AMPK; AMP-activated protein kinase; DMSO; dimethyl sulfoxide; EGFP; enhanced green fluorescence protein; EPAS1; endothelial PAS domain-containing protein 1 (known as HIF-2α); EPO; erythropoietin; esiRNA; endoribonuclease-prepared

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

The role of Myc and let-7a in glioblastoma, glucose metabolism and response to therapy

Keywords: GBM; glioblastoma multiforme; let-7a; lethal-7a; miRNA; microRNA; TCGA; The Cancer Genome Atlas; GLUT; glucose transporter; PKM2; pyruvate kinase M2; PDK; pyruvate dehydrogenase kinase; MGMT; O6-methylguanine-DNA methyltransferase; GSK3β; glycogen syntha

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2015 سفارش ترجمه

Des-acyl-ghrelin (DAG) normalizes hyperlactacidemia and improves survival in a lethal rat model of burn trauma

Keywords: DAG; des-acyl-ghrelin; EDL; extensor digitorum longus; PDC; pyruvate dehydrogenase complex; PDK; pyruvate dehydrogenase kinase; PDP; pyruvate dehydrogenase phosphatase; TBSA; total body surface area; Burn injury; Des-acyl-ghrelin (DAG); Hyperlactacidemia;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

T cell receptor-mediated activation is a potent inducer of macroautophagy in human CD8+CD28+ T cells but not in CD8+CD28− T cells

Keywords: mTOR; mammalian target of rapamycin; mTORC1/2; mTOR complex 1/2; TCR; T cell receptor; CMV; cytomegalovirus; PI3K; phosphoinositide 3-kinase; PKB; protein kinase B; PDK; phosphoinositide-dependent protein kinase 1; S6K1; S6 kinase 1; 4E-BP1; 4E-binding pr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

MDG-1, a polysaccharide from Ophiopogon japonicus, prevents high fat diet-induced obesity and increases energy expenditure in mice

Keywords: Ophiopogon japonicus; Polysaccharide; Anti-obesity; Energy expenditure; Diet induced obesity; Mitochondrial function; T2DM; type 2 diabetes mellitus; HFD; high fat diet; qPCR; quantitative real-time polymerase chain reaction; RER; respiratory exchange rat

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2014 سفارش ترجمه

Enzymes involved in l-lactate metabolism in humans

Keywords: ALT; alanine aminotransferase; ATP; adenine triphosphate; CoA; coenzyme A; FAD; flavin adenine dinucleotide; GPT; glutamate pyruvate transaminase; GSD; glycogen storage disease; LDH; lactate dehydrogenase; NAD+; oxidized nicotinamide adenine dinucleotide;

دانلود رایگان متن کامل مقاله ISI 64 صفحه سال انتشار : 2013 سفارش ترجمه

Ethnopharmacological communicationAnti-inflammatory activity of Sorbus commixta water extract and its molecular inhibitory mechanism

Keywords: Sc-WE; water extract of Sorbus commixta; LPS; lipopolysaccharide; NO; nitric oxide; PG; prostaglandin; iNOS; inducible NO synthase; COX; cyclooxy-genase; TNF; tumor necrosis factor; IL; interleukin; IKK; IκBα kinase; Akt; protein kinase B; PDK; phosphoi

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Anti-inflammatory activity of ethanol extract derived from Phaseolus angularis beans

Keywords: Pa-EE; ethanol extract of Phaseolus angularis; LPS; lipopolysaccharide; NO; nitric oxide; PG; prostaglandin; iNOS; inducible NO synthase; COX; cyclooxy-genase; IL; interleukin; IKK; I (B) kinase; Akt; protein kinase B; PDK; phosphoinositide-dependent kina

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Several agents and pathways regulate lipolysis in adipocytes

Keywords: Lipolysis; Adipose tissue; Intracellular signalling pathways; Hormone-sensitive lipase; Adipose triglyceride lipase; Antilipolysis; ACTH; adrenocorticotrophin hormone; AdPLA; adipose-specific phospholipase A2; Ang II; angiotensin II; ANP; atrial natriuret

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Targeting PI3K Signaling as a Therapeutic Approach for Colorectal Cancer

Keywords: Colon Cancer; Neoplasm; Signal Transduction; Genetics; Tumor; CRC; colorectal cancer; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; GPCR; G-protein-coupled receptor; IRS1; insulin receptor substrate 1; MEF; murine embryonic fibro

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

A quantitative mass spectrometry-based approach for identifying protein kinase clients and quantifying kinase activity

Keywords: CPK3; Mass spectrometry; Method; PDK; Peptide kinase assay; Protein phosphorylation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Transcriptional regulation of the insulin signaling pathway genes by starvation and 20-hydroxyecdysone in the Bombyx fat body

Keywords: InR; IRS; PI3K; PTEN; PDK; Akt; Transcriptional regulation; Starvation; 20-Hydroxyecdysone; Fat body; Bombyx mori

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

A COX-2 inhibitor nimesulide analog selectively induces apoptosis in Her2 overexpressing breast cancer cells via cytochrome c dependent mechanisms

Keywords: PI3K; phosphatidylinositol 3-kinase; AKT; protein kinase B; PDK; phosphoinositide-dependent kinase; MAPK; mitogen activated protein kinase; COX-2; cyclooxygenase 2; NSAIDs; non-steroidal anti-inflammatory drugs; PGE2; prostaglandin E2; Her2; human epiderm

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Phosphatidylinositol-3-Kinase/Akt Signaling Pathway and Kidney Cancer, and the Therapeutic Potential of Phosphatidylinositol-3-Kinase/Akt Inhibitors

Keywords: kidney; carcinoma; renal cell; D 21266; 1-phosphatidylinositol 3-kinase; mTOR protein; 17-HWT; 17-hydroxy-wortmannin; APC; alkylphosphocholine; ERK; extracellular regulated kinase; GSK3; glycogen synthase kinase-3; HIF; hypoxia-inducible factor; IC50; hal

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Hypoxia and the metabolic phenotype of prostate cancer cells

Keywords: ALDO; aldolase; CS; citrate synthase; COX; cytochrome c oxidase; DCA; dichloroacetate; G3PDH; glyceraldehyde-3-phosphate dehydrogenase; G6PDH; glucose-6-phosphate dehydrogenase; HK; hexokinase; HIF; hypoxia-inducible factor; LDH; lactate dehydrogenase; NR

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Protein kinase C-dependent antilipolysis by insulin in rat adipocytes

Keywords: β-AR; β-adrenergic receptor; α-AR; α-adrenergic receptor; PKA; protein kinase A; PKC; protein kinase C; PKB; protein kinase B; PDK; phosphoinositide-dependent protein kinase; PI3K; phosphatidylinositol 3-kinase; PIP3; phosphatidylinositol 3,4,5-tripho

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Signaling functions of phosphatidic acid

Keywords: ABA; abscisic acid; ARF; ADP ribosylation factor; C2; Ca2+-dependent phospholipid-binding; C2-PLD; PLD containing the C2 domain; CRD; cysteine-rich domain; DAG; diacylglycerol; DAG-PPi; diacylglycerol pyrophosphate; DGDG; digalactosyldiacylglycerol; DGK;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2006 سفارش ترجمه