دانلود مقالات ISI درباره TM، دامنه غشایی + ترجمه فارسی

اثرات اتانول بر انتقال گلیسینرژیک: از فارماکولوژی مولکولی تا پاسخ رفتاری

Ethanol effects on glycinergic transmission: From molecular pharmacology to behavior responses

Keywords: TM، دامنه غشایی; GlyR, glycine receptor; LGIC, ligand-gated ion channel; Gβγ, βγ dimer of G protein; TM, transmembrane domain; IL, large intracellular loop domain; GTP-γ-S, guanosine 5′-O-(3-thiotriphosphate); GST, glutathione-S-transferase; HEK, human embryonic kidneyGly

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Structural determinants of subtype selectivity and functional activity of angiotensin II receptors

Keywords: TM، دامنه غشایی; AngII, angiotensin II; AT1, angiotensin II receptor type 1; AT2, angiotensin II receptor type 2; GPCR, G-protein coupled receptor; TM, transmembrane domain; EL, extracellular loop; IL, intracellular loop; MD, molecular dynamics; NMR, nuclear magnetic reso

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

ABC-B transporter genes in Dirofilaria immitis

Keywords: TM، دامنه غشایی; Dirofilaria immitis; P-glycoprotein; Genetic identificationML, macrocyclic lactones; LOE, loss of efficacy; Kb, kilobase; Tm, melting temperature; TM, transmembrane domain; Pgp, P-glycoprotein; ATP, adenosine triphosphate; IVM, ivermectin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Length of the TM3-4 loop of the glycine receptor modulates receptor desensitization

Keywords: TM، دامنه غشایی; CLR, Cys-loop receptors; GlyR, glycine receptor; ICD, intracellular domain; TM, transmembrane domain; GLIC, prokaryotic receptor isolated from Gloeobacter violaceusCys-loop receptor; Glycine receptor; TM3-4 loop; Basic residues; Desensitization

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

A membrane proximal helix in the cytosolic domain of the human APP interacting protein LR11/SorLA deforms liposomes

Keywords: TM، دامنه غشایی; TM, transmembrane domain; CT, cytosolic domain; APP, amyloid precursor protein; AD, Alzheimer's disease; MBP, maltose binding protein; DMPC, 1,2-dimyristoyl-sn-glycerophosphocholine; DOPE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine; 1,2-DOG, 1,2-dioleo

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

The evolutionary analysis reveals domain fusion of proteins with Frizzled-like CRD domain

Keywords: TM، دامنه غشایی; FZD, Frizzled; CRD, Cysteine-rich domain; Fz-CRD, Frizzled-like Cysteine-rich domain; TM, transmembrane domain; 7TM, seven-transmembrane domain; GPCR, G-protein-coupled receptor; SFRP, secreted Frizzled-related protein; Smo, Smoothened; MuSK, muscle skele

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

High affinity ligands and potent antagonists for the α1D-adrenergic receptor. Novel 3,8-disubstituted [1]benzothieno[3,2-d]pyrimidine derivatives

Keywords: TM، دامنه غشایی; α1D-Adrenergic receptor; Antagonist; Ligand; [1]Benzothieno[3,2-d]pyrimidineAR, adrenergic receptor; BPH, benign prostatic hypertrophy; CNS, central nervous system; TM, transmembrane domain; IL, intracellular loop; XL, extracellular loop; PP, phenylpipera

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Bacterial origin of a diverse family of UDP-glycosyltransferase genes in the Tetranychus urticae genome

Keywords: TM، دامنه غشایی; Tetranychus urticae; UDP-glycosyltransferase; Detoxification; Horizontal gene transfer; Arthropoda; ChelicerataaaID, amino acid identity; CDS, coding sequences; GT, glycosyltransferase; HGT, horizontal gene transfer; TM, transmembrane domain; TSA, transcr

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

Bacillus thuringiensis Cry and Cyt mutants useful to counter toxin action in specific environments and to overcome insect resistance in the field

Keywords: TM، دامنه غشایی; Bt, Bacillus thuringiensis; APN, aminopeptidase; ALP, alkaline phosphatase; DN, dominant negative; CR, cadherin repeat; TM, transmembrane domain; MPED, membrane proximal ectodomainBacillus thuringiensis; Cry toxin; Cyt toxin; Dominant negative mutant; Ant

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Molecular genetic and biochemical approaches for defining lipid-dependent membrane protein folding

Keywords: TM، دامنه غشایی; TM, transmembrane domain; PE, phosphatidylethanolamine; PG, phosphatidylglycerol; CL, cardiolipin; PA, phosphatidic acid; PS, phosphatidylserine; lys, lysyl; PC, phosphatidylcholine; GlcDAG, monoglucosyl diacylglycerol; GlcGlcDAG, diglucosyl diacylglycero

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Missense mutations in Otopetrin 1 affect subcellular localization and inhibition of purinergic signaling in vestibular supporting cells

Keywords: TM، دامنه غشایی; Otop1, Otopetrin 1; tlt, Tilted; mlh, Mergulhador; OD, Otopetrin domain; TM, transmembrane domain; [Ca2+]i, intracellular calcium concentration; ZO-1, Zona Ocluden-1Vestibular; Otoconia; Otopetrin; Calcium; Purinergic signaling

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Modulation of histamine H3 receptor function by monovalent ions

Keywords: TM، دامنه غشایی; GPCR, G protein-coupled receptor; h, human; H3R, histamine H3 receptor; H4R, histamine H4 receptor; TM, transmembrane domain; HA, histamine; THIO, thioperamide; NAMH, Nα-methylhistamineHistamine H3 receptor; Constitutive activity; Gi/Go-proteins; GTPase;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Properties of the intracellular transient receptor potential (TRP) channel in yeast, Yvc1

Keywords: TM، دامنه غشایی; DIDS, 4,4-diisothiocyanato-stilbene-2,2-disulfonic acid; DTT, dithiothreitol; GFP, green fluorescent protein; GOF, gain-of-function; InsP3, inositol 1,4,5-triphosphate; Pmc1, vacuolar Ca2+-ATPase; TM, transmembrane domain; TRP, transient receptor potentia

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

The role of blood cell membrane lipids on the mode of action of HIV-1 fusion inhibitor sifuvirtide

Keywords: TM، دامنه غشایی; CHR, C-terminal heptad repeat; NHR, N-terminal heptad repeat; TM, transmembrane domain; FP, fusion peptide; PBD, pocket binding domain; LBD, lipid-binding domain; Env, envelope; PC, phosphatidylcholine; POPC, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholi

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Comparison of the pharmacological properties of human and rat histamine H3-receptors

Keywords: TM، دامنه غشایی; GPCR, G protein-coupled receptor; GTPγS, guanosine 5′-[γ-thio]triphosphate; h, human; r, rat; β2AR, β2-adrenoceptor; H3R, histamine H3-receptor; H4R, histamine H4-receptor; TM, transmembrane domain; JNJ-7753707, (4-fluorophenyl)(1-methyl-2-an-1H-imidazol-

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Novel structural insights for drug design of selective 5-HT2C inverse agonists from a ligand-biased receptor model

Keywords: TM، دامنه غشایی; 5-HT2C inverse agonists; Ligand-biased homology modeling; Pharmacophore; Docking-scoring; Virtual ligand screeningGPCR, G-protein coupled receptor; TM, transmembrane domain; EL, extracellular loop; IL, intracellular loop; PDB, protein Data Bank; VLS, virt

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

Zebrafish β-adrenergic receptor mRNA expression and control of pigmentation

Keywords: TM، دامنه غشایی; β-AR, beta adrenergic receptor; MC, melanocyte; hpf, hours post-fertilization; dpf, days post-fertilization; mpf, months post-fertilization; EST, expressed sequence tag; Ct, threshold cycle; TM, transmembrane domain; Mbp, megabase pairs; mM, millimole; μg

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Natural History of Recessive Inheritance of DMT1 Mutations

Keywords: TM، دامنه غشایی; Epo, Erythropoietin; TM, Transmembrane domain

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Peptide Mimic of the HIV Envelope gp120–gp41 Interface

Keywords: TM، دامنه غشایی; HIV, human immunodeficiency virus; ED, ectodomain; TM, transmembrane domain; CT, cytoplasmic tail domain; FP, fusion peptide; DSL, disulfide bond loop; wt, wild type; NEM, N-ethylmaleimide; Ac, iodoacetate; RP-HPLC, reverse-phase HPLC; PBS, phosphate-buff

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

The L293 residue in transmembrane domain 2 of the 5-HT3A receptor is a molecular determinant of allosteric modulation by 5-hydroxyindole

Keywords: TM، دامنه غشایی; 5-HT3A receptor; Allosteric modulation; Gating; Desensitization; Structure–function; Electrophysiology5-HT3, 5-hydroxytryptamine (serotonin) type 3; nACh, nicotinic acetylcholine; TM, transmembrane domain; 5-HI, 5-hydroxyindole; HEK cells, human embryonic

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Homology modeling of MT1 and MT2 receptors

Keywords: TM، دامنه غشایی; Melatonin; GPCRs; Activation; DockingGPCR, G-protein coupled receptor; TM, transmembrane domain

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2008 سفارش ترجمه

Disulfide Trapping the Mechanosensitive Channel MscL into a Gating-Transition State

Keywords: TM، دامنه غشایی; MS, mechanosensitive; TM, transmembrane domain; GOF, gain-of-function; LOF, loss-of-function; E. coli, Escherichia coli; DTT, dithiothreitol; OD, optical density; Po, open probability

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Evolution of melanocortin receptors in teleost fish: The melanocortin type 1 receptor

Keywords: TM، دامنه غشایی; el, extracellular loop; il, intracellular loop; Hsa, Homo sapiens; Mcr, melanocortin receptor; TM, transmembrane domain; Xma, Xiphophorus maculatusMc1r; MSH; Pigment cell; Melanoma; Medaka; Xiphophorus; Zebrafish

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

NTS2 modulates the intracellular distribution and trafficking of NTS1 via heterodimerization

Keywords: TM، دامنه غشایی; NT, neurotensin; GPCR(s), G protein-coupled receptor(s); TM, transmembrane domain; COS-7 cells, green African monkey kidney cells; MAPK, mitogen-activated protein kinase; ERK1/2, extracellular signal-regulated kinases 1/2; ER, endoplasmic reticulum; NGS,

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Molecular aspects of the histamine H3 receptor

Keywords: TM، دامنه غشایی; H3R, histamine H3 receptor; hH3R, human histamine H3 receptor; PLA2, phospholipase A2; TM, transmembrane domain; GPCR, G-protein coupled receptor; NHE, Na+/H+-exchanger; PI3K, phospho-inositol-3-kinase; PTX, pertussis toxin; PKA, protein kinase KHistamine

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

AT1 receptor blocker-insensitive mutant AT1A angiotensin receptors reveal the presence of G protein-independent signaling in C9 cells

Keywords: TM، دامنه غشایی; Ang II, angiotensin II; AT1-R, type I angiotensin receptor; AT1A-R, type 1A angiotensin receptor; AT1B-R, type 1B angiotensin receptor; MAP kinase, mitogen-activated protein kinase; ERK, extracellular signal-regulated kinase; TM, transmembrane domain; DME

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Identification of amino acid residues participating in the energy coupling and proton transport of Streptomyces coelicolor A3(2) H+-pyrophosphatase

Keywords: TM، دامنه غشایی; DTT, dithiothreitol; H+-PPase, H+-translocating inorganic pyrophosphatase; ScPP, S. coelicolor A3(2) H+-PPase; TM, transmembrane domain; WT, wild typeEnergy coupling; H+-pyrophosphatase; Random mutagenesis; Proton pump

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

The role of transporters in cellular heme and porphyrin homeostasis

Keywords: TM، دامنه غشایی; Heme; Porphyrin; Transporter; Mitochondria; MembraneABC, ATP-binding cassette; FLVCR, feline leukemia virus receptor C; HCP1, heme carrier protein 1; MFS, major facilitator superfamily; PPIX, protoporphyrin IX; TM, transmembrane domain

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2007 سفارش ترجمه

Molecular basis of voltage dependence of connexin channels: An integrative appraisal

Keywords: TM، دامنه غشایی; Connexin channel/hemichannel; Transjunctional voltage dependence; Membrane potential dependence; Voltage gating; Voltage sensorCx, connexin; NT and CT, amino and carboxyl terminus; CL, cytoplasmic loop; TM, transmembrane domain; Ij, junctional current; Gj

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2007 سفارش ترجمه

The opioid ligand binding of human μ-opioid receptor is modulated by novel splice variants of the receptor

Keywords: TM، دامنه غشایی; MOR, μ-Opioid receptor; BRET, Bioluminescence resonance energy transfer; Rluc, Renilla luciferase; DsRed, Destabilized red fluorescence protein; SV, Splice variant; TM, Transmembrane domain

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

h-Goliath, paralog of GRAIL, is a new E3 ligase protein, expressed in human leukocytes

Keywords: TM، دامنه غشایی; GRAIL, gene related to anergy in lymphocytes; GREUL1, Goliath Related E3 Ubiquitin Ligase 1; G1RP, g1-related protein; PA, protease-associated; SP, signal peptide; TM, transmembrane domain; HD, hydrophobic domain; RING, really interesting new gene; UbcH,

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Point mutations within the LdNT2 nucleoside transporter gene from Leishmania donovani confer drug resistance and transport deficiency

Keywords: TM، دامنه غشایی; TM, transmembrane domain; ENT, equilibrative nucleoside transporter; ORF, open reading frame; GFP, green fluorescent protein; G418, geneticin; PCR, polymerase chain reaction; FoB, formycin B; PBS, phosphate buffered salineLeishmania; Nucleosides; Transpor

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Structure activity and molecular modeling analyses of ribose- and base-modified uridine 5′-triphosphate analogues at the human P2Y2 and P2Y4 receptors

Keywords: TM، دامنه غشایی; PLC, phospholipase C; HEPES, N-(2-hydroxyethyl)-piperazine-N′-2-ethanesulfonic acid; ATP, adenosine 5′-triphosphate; CTP, cytidine 5′-triphosphate; GTP, guanosine 5′-triphosphate; TM, transmembrane domain; TBAP, tetrabutylammonium dihydrogen phosphate; TE

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Alternate Interfaces May Mediate Homomeric and Heteromeric Assembly in the Transmembrane Domains of SNARE Proteins

Keywords: TM، دامنه غشایی; SNARE; membrane protein; vesicle fusion; thermodynamics; disulfide crosslinkingGpA, glycophorin A; AUC, analytical ultracentrifugation; SNARE, soluble NSF attachment protein receptors; TM, transmembrane domain; CuOP, copper phenanthroline; Syx, syntaxin;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه