Keywords: ANT; adenine nucleotide translocator; Cyt C; cytochrome C; Cys A; cyclosporine A; FCCP; carbonylcyanide-p-(trifluoromethoxy) phenyl-hydrazone; GCDCA; glycochenodeoxycholic acid; IM; inner membrane; MβCD; methyl-β-cyclodextrin; MMP; mitochondrial membran
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Ferroptosis is a lysosomal cell death process
Keywords: Ferroptosis; STAT3; Lysosomal cell death; Autophagy; Cathepsin; PDAC; pancreatic ductal adenocarcinoma; STAT3; signal transducer and activator of transcription 3; GPX4; glutathione peroxidase 4; NRF2; nuclear factor erythroid 2-related factor 2; Q-PCR; qu
BDNF mimetic alleviates body weight gain in obese mice by enhancing mitochondrial biogenesis in skeletal muscle
Keywords: 7,8-DHF; 7,8-Dihydroxyflavone; ACC; accetyl CoA carboxylase; AdipoQ; adiponectin; AMPK; AMP-activated protein kinase; ANGPT-L3; angiopoietin-like 3; BAT; brown adipose tissue; BDNF; brain derived neurotrophic factor; CREB; cAMP responsive element binding
Post-translational modifications of VDAC1 and VDAC2 cysteines from rat liver mitochondria
Keywords: VDAC; voltage-dependent anion selective channel; OMM; outer mitochondrial membrane; PTM; post-translational modification; ROS; reactive oxygen species; MS; mass spectrometry; HTP; hydroxyapatite; Cysteine over-oxidation; Orbitrap fusion tribrid; Mitochond
The ATP-stimulated translocation promoter (ASTP) activity of glycerol kinase plays central role in adipogenesis
Keywords: Glycerol kinase; Glycerol kinase deficiency; Metabolic flux analysis; Moonlighting proteins; Adipogenesis; ASTP; ATP stimulated translocation promoter; GK; glycerol kinase; GKD; glycerol kinase deficiency; VDAC; voltage-dependent anion channel; Gyk; murin
Sirtuin 3-dependent mitochondrial redox homeostasis protects against AGEs-induced intervertebral disc degeneration
Keywords: IVD; intervertebral disc; NP; nucleus pulposus; SIRTs; Sirtuins; AGEs; advanced glycation end products; NMN; nicotinamide mononucleotide; SKQ1; Visomitin; MitoTEMPO; (2-(2,2,6,6-Tetramethylpiperidin-1-oxyl-4-ylamino)-2-oxoethyl) triphenylphosphonium chlor
Morusin induces paraptosis-like cell death through mitochondrial calcium overload and dysfunction in epithelial ovarian cancer
Keywords: Morusin; Paraptosis-like cell death; EOC; VDAC; Mitochondrial Ca2+ overload; Mitochondrial dysfunction; EOC; epithelial ovarian cancer; VDAC; voltage-dependent anion channel; DIDS; 4, 4â²-diisothiocyanostilbene-2, 2â²-disulfonic acid; NAC; N-acetyl-l-cy
The mechanism of tumour cell death by metal-based anticancer drugs is not only a matter of DNA interactions
Keywords: 15-LOX-1; 15-lipoxygenase; AIF; apoptosis inducing factor; APC; adenomatous polyposis coli; AKT or PKB; protein kinase B; ATG16L2; autophagy related 16 like 2; AUC; area under the curve; Bad; Bcl-2 associated death promoter; Bcl-2; B-cell lymphoma 2; Bcl-
The major outer membrane protein of Legionella pneumophila Lpg1974 shows pore-forming characteristics similar to the human mitochondrial outer membrane pore, hVDAC1
Keywords: VDAC; voltage-dependent anion-selective channel, synonym for mitochondrial porin; Legionella pneumophila; Porin; Lpg1974; hVDAC1; Voltage-dependence; Lipid bilayer membrane;
Mitochondria-associated membranes (MAMs): An emerging platform connecting energy and immune sensing to metabolic flexibility
Keywords: Organelle communication; Mitochondria-associated membranes; Nutrients; Microbiome; Innate immunity; Insulin sensitivity; Metabolic diseases; Ca2+; calcium; CLRs; C-type lectin receptors; CypD; cyclophilin D; DAMPs; Danger-Associated Molecular patterns; ER
Neuroprotective effect of zolpidem against glutamate-induced toxicity is mediated via the PI3K/Akt pathway and inhibited by PK11195
Keywords: ANC; adenine nucleotide carrier; H2O2; hydrogen peroxide; LDH; lactate dehydrogenase; mPTP; mitochondrial permeability transition pore; PI3K; phosphatidylinositol-3-kinase; PK11195; 1-(-2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide
Phosphorylation of rat brain purified mitochondrial Voltage-Dependent Anion Channel by c-Jun N-terminal kinase-3 modifies open-channel noise
Keywords: VDAC; Phosphorylation; Open-channel noise; 1/f noise (flicker noise); VDAC; Voltage-Dependent Anion Channel; JNK3; c-Jun N-terminal Kinase-3; PhosphoVDAC; Phosphorylated VDAC;
The phosphorylation of Metaxin 1 controls Bak activation during TNFα induced cell death
Keywords: AMOMP; apoptotic mitochondrial outer membrane permeability; BdGBM; Bax deficient glioblastoma multiforme; CHX; cycloheximide; IP; immunoprecipitation; IVT; in vitro translated; Mtx; metaxin; MOM; mitochondrial outer membrane; PP1; PP1-analog II 1NM-PP1; V
Progesterone treatment modulates mRNA OF neurosteroidogenic enzymes in a murine model of multiple sclerosis
Keywords: CC1; anti-adenomatours polyposis coli clone CC1; CD11b; cluster of differentiation molecule 11B; CFA; complete Freund adjuvant; DHP; dihydroprogesterone; EAE; experimental autoimmune encephalomyelitis; Fis1; mitochondrial fission 1; GABA; gamma-aminobutyr
Evaluation of biological properties of 3,3â²,4,4â²-benzophenonetetracarboxylic dianhydride derivatives and their ability to inhibit hexokinase activity
Keywords: Virtual High-Throughput Screening; Hexokinase II; P19 cells; Cytotoxicity; Mitochondrial membrane potential; BDTA; 3,3â²,4,4â²-benzophenonetetracarboxylic dianhydride; ECC; embryonal carcinoma cells; GK; glukokinase; G6P; glucose 6-phosphate; G6PD; gluc
Inhibition of Drp1 protects against senecionine-induced mitochondria-mediated apoptosis in primary hepatocytes and in mice
Keywords: ALT; Alanine aminotransferase; ActD; Actinomycin D; CYP; Cytochrome P450; CQ; Chloroquine; Drp1; Dynamin-related protein 1; DHPAs; Dehydropyrrolizidine alkaloids; DHR; dehydroretronecine; EM; Electron microscopy; GSH; Glutathione; GAPDH; Glyceradehyde-3-p
Pro-apoptotic effects of lipid oxidation products: HNE at the crossroads of NF-κB pathway and anti-apoptotic Bcl-2
Keywords: AIF; Apoptosis inducing factor; ANT; Mitochondrial inner membrane protein adenine nucleotide translocase; Apaf-1; Apoptotic protease activating factor 1; BAG3; Bcl-2-associated athanogene domain 3; Bcl-2; B-cell lymphoma-2; HHE; 4-hydroxyhexenal; HNE; 4-H
Mag-Fluo4 in T cells: Imaging of intra-organelle free Ca2Â + concentrations
Keywords: AM; acetoxymethylester; [Ca2Â +]ER; free luminal endoplasmic reticular Ca2Â + concentration; [Ca2Â +]i; free cytosolic Ca2Â + concentration; [Ca2Â +]mito; free luminal mitochondrial Ca2Â + concentration; cADPR; cyclic adenosine diphosphoribose; ER; endopl
VDAC electronics: 4. Novel electrical mechanism and thermodynamic estimations of glucose repression of yeast respiration
Keywords: VDAC; the voltage-dependent anion channel; OMP; the mitochondrial outer membrane potential; MOM; the mitochondrial outer membrane; MIMS; the mitochondrial intermembrane space; DHe; the external NADH dehydrogenase(s) of the mitochondrial inner membrane; VD
Chlamydia trachomatis Prevents Apoptosis Via Activation of PDPK1-MYC and Enhanced Mitochondrial Binding of Hexokinase II
Keywords: EB; elementary body; RB; reticulate bodies; PI3K; phosphatidylinositol 3-kinase; HKII; hexokinase II; VDAC; voltage-dependent anion channel; CTL2; Chlamydia trachomatis L2; p.i.; post-infection; TNF-α; tumor necrosis factor-α; PARP; poly-(ADP-ribose) po
ReviewRegulation of Calcium Homeostasis by ER Redox: A Close-Up of the ER/Mitochondria Connection
Keywords: Ca2Â +; Â calcium; MAM; mitochondria-associated membrane; ER; endoplasmic reticulum; IP3R; inositol 1,4,5-trisphosphate receptor; RyR; ryanodine receptor; VDAC; voltage-dependent anion channel; MCU; mitochondrial Ca2Â + uniporter; SERCA; sarcoplasmic/ER C
Connection of Protein Transport and Organelle Contact Sites in Mitochondria
Keywords: VDAC; voltage-dependent anion channel; ER; endoplasmic reticulum; ERMES; ER-mitochondria encounter structure; Mmm1; maintenance of mitochondrial morphology protein 1; Mdm10; mitochondrial distribution and morphology protein 10; SMP; synaptotagmin-like m
Mitochondrial hyperpolarization in iPSC-derived neurons from patients of FTDP-17 with 10+16 MAPT mutation leads to oxidative stress and neurodegeneration
Keywords: 2-NBDG; 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose; AD; Alzheimer's disease; CBD; Corticobasal Degeneration; CSF; Cerebrospinal Fluid; DHE; Dihydroethidium; ETC; Electron Transport Chain; FCCP; Carbonyl cyanide-4-(trifluoromethoxy)pheny
Research articleChanges in the mitochondrial protein profile due to ROS eruption during ageing of elm (Ulmus pumila L.) seeds
Keywords: Elm (Ulmus pumila L.) seed; Ageing; Mitochondria; ROS; VDAC; Protein carbonylation; CDT; controlled deterioration treatment; CMXRos; MitoTracker Red CMXRos; cyt c; cytochrome c; 2-DE; two-dimensional electrophoresis; ETC; electron transport chain; H2DCFDA
Evidence of proteolipid domain formation in an inner mitochondrial membrane mimicking model
Keywords: mtCK; Mitochondrial creatine kinase; PC; Phosphatidylcholine; PE; Phosphatidylethanolamine; CL; Cardiolipin; IAEDANS; 5-((((2-iodoacetyl) amino) ethyl) amino) naphthalene-1-sulfonic acid; ANT; Adenylic Nucleotide Translocator; VDAC; Voltage Dependent Anio
GQSAR modeling and combinatorial library generation of 4-phenylquinazoline-2-carboxamide derivatives as antiproliferative agents in human Glioblastoma tumors
Keywords: GBM; Glioblastoma multiforme; TSPO; translocator protein; MPTP; mitochondrial permeability transition pore; ANT; adenine nucleotide transporter; VDAC; voltage dependent anion channel; QSAR; quantitative structure activity relationship; GQSAR; Group QSAR;
Identification and characterization of vp7 gene in Bombyx mori cytoplasmic polyhedrosis virus
Keywords: BmCPV; Bombyx mori cytoplasmic polyhedrosis virus; RNAi; RNA interference; VDAC; Voltage-dependent anion-selective channel-like isoform; CPVs; Cytoplasmic polyhedrosis viruses; TnCPV-15; Trichoplusiani cypovirus type 15; ORF; Open reading frame; NSP; Non-
2102Ep embryonal carcinoma cells have compromised respiration and shifted bioenergetic profile distinct from H9 human embryonic stem cells
Keywords: ADP; adenosine diphosphate; AK; adenylate kinase; ANT; adenine nucleotide translocator; ATP; adenosine triphosphate; BSA; bovine serum albumin; CAT; carboxyatractyloside; CK; creatine kinase; CKB; brain-type creatine kinase; CKMT1A; creatine kinase, mitoc
Gen-27, a newly synthesized flavonoid, inhibits glycolysis and induces cell apoptosis via suppression of hexokinase II in human breast cancer cells
Keywords: BCA; bicinchoninic acid; Cyt c; cytochrome c; DAPI; 4â²,6-diamidino-2-phenylindole; DCFH/DA; 2â²,7â²-dichlorodihydrofluorescein diacetate; DMSO; dimethylsulfoxide; FBS; Fetal bovine serum; HKII; hexokinase II; LDHA; lactate dehydrogenase; MMP; mitochon
Sigma 1 receptor activation modifies intracellular calcium exchange in the G93AhSOD1 ALS model
Keywords: ALS; amyotrophic lateral sclerosis; AMPA; Î-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; CTCF; corrected total cell fluorescence; ERMCC; ER mitochondria Ca2+ cycle; G93A; G93AHSOD1; MAM; mitochondria-associated ER membrane; NE-100; 4-methoxy-3-(2-
Metal complexes targeting the Translocator Protein 18Â kDa (TSPO)
Keywords: ACBP; acyl coenzyme-A binding protein; AIF; apoptosis inducing factor; ANT; Adenine Nucleotide Translocase; B; boron; BDZ; benzodiazepine; BFC approach; bifunctional chelate approach; BNCT; Boron Neutron Capture Therapy; CBR; Central-type Benzodiazepine R
The translocator protein (18Â kDa) and its role in neuropsychiatric disorders
Keywords: 3α-HSD; 3α-hydroxysteroid dehydrogenase; 3β-HSD; 3β-hydroxysteroid dehydrogenase/Î5âÎ4; AIF; apoptosis inducing factor; AD; Alzheimer's disease; ANT; adenine nucleotide translocator; AP-1; activator protein 1; APAF-1; apoptotic peptidase activat
19th European Bioenergetics Conference-Preface
Keywords: ANT; adenine nucleotide translocator; CoQ; coenzyme Q; EBEC; European bioenergetics conference; IF1; inhibitory factor 1; IMM; inner mitochondrial membrane; ISP-HD; iron-sulfur protein head domain; Luca; last universal common ancestor; OMM; outer mitoch
The VDAC channel: Molecular basis for selectivity
Keywords: VDAC; Permeation; Mitochondrion; Pore; ATP; Optimization;
Overexpression of human SOD1 in VDAC1-less yeast restores mitochondrial functionality modulating beta-barrel outer membrane protein genes
Keywords: SOD1; VDAC; Mitochondria; S. cerevisiae; Gene expression; tom40; sam50
Cytoprotective effect of Centella asiatica is mediated through the modulation of mitochondrial voltage-dependent anion channel (VDAC) and scavenging of free radicals
Keywords: VDAC; Ion channel; Centella asiatica; Apoptosis; Mitochondria; Ischaemia
Lack of phosphatidylethanolamine N-methyltransferase in mice does not promote fatty acid oxidation in skeletal muscle
Keywords: BSA; bovine serum albumin; DMEM; Dulbecco's modified Eagle's medium; ER; endoplasmic reticulum; HF; high-fat; PC; phosphatidylcholine; PE; phosphatidylethanolamine; PEMT; phosphatidylethanolamine N-methyltransferase; SREBP; sterol-regulatory element bindi
The N-terminus of VDAC: Structure, mutational analysis, and a potential role in regulating barrel shape
Keywords: Voltage-dependent anion selective channel; VDAC; Mitochondrial porin; N-terminus; Voltage gating; β-Barrel
Current state of theoretical and experimental studies of the voltage-dependent anion channel (VDAC)
Keywords: VDAC; Molecular Dynamics simulations; Brownian Dynamics simulations; Mitochondrial transport; Beta-barrel channel reconstitution; pH regulation;
Disruption of desmin-mitochondrial architecture in patients with regurgitant mitral valves and preserved ventricular function
Keywords: heart failure; mitochondria; cardiomyocyte; mitral regurgitation; 4-HNE; 4-hydroxynonenal; BSA; bovine serum albumin; LV; left ventricular; LVED; left ventricular end-diastolic; LVEF; left ventricular ejection fraction; LVES; left ventricular end-systolic
Restricted ADP movement in cardiomyocytes: Cytosolic diffusion obstacles are complemented with a small number of open mitochondrial voltage-dependent anion channels
Keywords: CK; creatine kinase; DC; diffusion coefficient; GAMT; GuanidinoAcetate MethylTransferase; MOM; mitochondrial outer membrane; VDAC; voltage-dependent anion channel; Oxidative phosphorylation; Regulation; Rat cardiomyocytes; Voltage-dependent anion channel
Intracellular Ca2+ signaling and Ca2+ microdomains in the control of cell survival, apoptosis and autophagy
Keywords: Apoptosis; Autophagy; Endoplasmic reticulum; IP3 receptor; Lysosomes; Mitochondria; AMBRA1; autophagy/Beclin 1 regulator 1; AMPK; AMP-activated kinase; ATF4; activating transcription factor-4; Atg; autophagy-related; BIRD-2; Bcl-2/IP3R disruptor-2; CREB;
On the structural possibility of pore-forming mitochondrial FoF1 ATP synthase
Keywords: OSCP; oligomycin sensitivity conferring protein; ptp; permeability transition pore; mpt; mitochondrial permeability transition; pmf; proton motive force; ÎÑ°m; electric potential across the inner mitochondrial membrane; MMC; mitochondrial mega channel; k
Insulin-like growth factor 1 (IGF-1) therapy: Mitochondrial dysfunction and diseases
Keywords: ÎΨm; membrane potential; AD; Alzheimer's disease; AMPK; adenosine-monophosphate-activated kinase; ATG proteins; autophagy-related proteins; ATP; adenosine triphosphate; CaMKs; calcium-calmodulin-activated kinases; CDKs; cyclin-dependent kinases; CNS;
GSTZ1 expression and chloride concentrations modulate sensitivity of cancer cells to dichloroacetate
Keywords: [Clâ]; chloride concentration; DCA; dichloroacetate; ERK; extracellular signal-regulated kinase; GSTZ1; glutathione transferase Z1; HER2; human epidermal growth factor receptor 2; PDC; pyruvate dehydrogenase complex; PDK; pyruvate dehydrogenase kinase;
Redox biology and the interface between bioenergetics, autophagy and circadian control of metabolism
Keywords: ARE; antioxidant response element; ATP; adenosine triphosphate; 5-hmC; hydroxymethylcytosine; ATG; AuTophaGy related; BNIP; Bcl-2/adenovirus E18 19-kDa-interacting protein; Drp1; dynamin related protein 1; EpRE; electrophile response element; eNOS; endoth
Channel characteristics of VDAC-3 from Arabidopsis thaliana
Keywords: VDAC; Cell-free synthesis; Arabidopsis; Channel;
Assembly of human mitochondrial ATP synthase through two separate intermediates, F1-c-ring and b-e-g complex
Keywords: MASC assay; mitochondrial activity of SLO-permeabilized cells assay; VDAC; voltage-dependent anion channel of mitochondria; ATP synthase; FoF1; Mitochondrial activity of SLO-permeabilized cells assay; d-Subunit; ATP5H; Stator stalk; Assembly;
Evolving understanding of translocator protein 18Â kDa (TSPO)
Keywords: TSPO; translocator protein 18Â kDa; PBR; peripheral-type benzodiazepine receptor; RsTSPO; TSPO from Rhodobacter sphaeroides; BcTSPO; TSPO from Bacillus cereus; mTSPO; TSPO from mouse; MPTP; mitochondrial permeability transition pore; VDAC; voltage depende
The mitochondrial unselective channel in Saccharomyces cerevisiae
Keywords: ANT; adenine-nucleotide translocase; CoxIV1-22; mitochondrial targeting sequence of cytochrome oxidase subunit IV; CPR3; yeast mitochondrial cyclophilin; CsA; cyclosporine A; CypD; cyclophilin D; dUb; decylubiquinone; dVO4; decavanadate; EGTA; ethylene gl