Keywords: Alzheimer's disease; Amyloid β; Unfolded protein response; XBP1; Neurodegeneration; Aging;
مقالات ISI (ترجمه نشده)
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Keywords: QPA; quaternary protoberberine alkaloid; TF; transcriptional factor; UC; ulcerative colitis; IEC-6; intestinal epithelial cell-6; XBP1; X-box-binding protein 1; MIC; minimal inhibitory concentration; SAR; structure-activity relationship; SASP; Sulfasalazi
Keywords: ATM; ataxia telangiectasia mutated; ATR; ATM-Rad3-related; AMPK; AMP-activated protein kinase; AD; Alzheimer's disease; ARE; antioxidant response element; ATF6; activating transcription factor 6; BiP; binding immunoglobulin protein; BRAC1; Breast cancer 1
Keywords: 18S; 18S ribosomal RNA; 36B4; acidic ribosomal protein 36B4; Acc1; acetyl-CoA carboxylase α; Acox1; acyl-CoA oxidase 1; Apob; apolipoprotein B; ARE; antioxidant response element; AST; aspartate aminotransferase; ALT; alanine aminotransferase; ATF4; activ
Keywords: α-MSH; α-melanocyte stimulating hormone; AGRP; agouti related protein; ARC; arcuate nucleus of hypothalamus; ATF; activating transcription factor; BBB; blood-brain barrier; CRH; corticotropin-releasing hormone; CSF; cerebrospinal fluid; Cys; cysteine; D
Kimchi methanol extracts attenuate hepatic steatosis induced by high cholesterol diet in low-density lipoprotein receptor knockout mice through inhibition of endoplasmic reticulum stress
Keywords: ATF6; activating transcription factor 6; Bcl-2; B-cell lymphoma 2; Bax; Bcl-2-associated X protein; CAT; catalase; CHOP; CCAAT-enhancer-binding protein homologous protein; cIAP; inhibitor of apoptosis protein; DAB; diaminobenzidine; ECL; enhanced chemilum
Keywords: APC; antigen presenting cells; CRD; carbohydrate recognition domain; DCs; dendritic cells; GDF-15; growth differentiation factor-15; IL; interleukin; IDO; indoleamine 2,3-dioxygenase; IFN-γ; interferon-γ; LXR; liver X receptors; M-CSF; macrophage-colony
Keywords: 4-PBA; 4-phenylbutyric acid; ARA; arachidonic acid; ATF6; activating transcription factor 6; BiP or Grp78; 78-kDa glucose regulated protein; COX; cyclooxygenase; CYP; cytochrome P450; DHA; docosahexaenoic acid; eIF2α; eukaryotic translation initiation fa
Keywords: 15-E2-IsoLG; isolevuglandin E2; 4-HNE; 4-hydroxy-2-nonenal; α-SMA; alpha Smooth Muscle Actin; ANOVA; analysis of variance; ATF4; Activating transcription factor 4; BiP; Immunoglobulin heavy chain binding protein; BrdU; 5-Bromo-2-Deoxyuridine; carboxy-DCF
Keywords: ER stress; KSHV; IRE1α; PERK; Primary effusion lymphoma; Unfolded protein response; ATF6; activating transcription factor-6; CHOP; CCAAT/enhancer-binding protein-homologous protein; ER; endoplasmic reticulum; GADD34; growth arrest and DNA damage gene-34;
Keywords: BD; Bipolar Disorder; STEP-BD; Systematic Treatment Enhancement Program for Bipolar disorder; DFNB31; Deafness, Autosomal Recessive 31; SORCS2; Sortilin-Related VPS10 Domain Containing Receptor 2; NRXN1; Neurexin 1; CNTNAP2; Contactin Associated Protein-L
Keywords: DC; dendritic cell; ER; endoplasmic reticulum; IDO; indoleamine 2,3-dioxygenase; IFN-γ; interferon gamma; iNOS; inducible nitric oxide synthase; IRE1α; inositol-requiring enzyme 1 alpha; MAPK; mitogen-activated protein kinase; PD1; programmed death 1; P
Keywords: A; sodium/alanine symporter; ADMA; asymmetric dimethylarginine; ASC; amiloride-sensitive sodium channel; CBS; cystathionine β-synthase; CHOP; C/EBP homologous protein; cSHMT or mSHMT; cytosolic or mitochondrial serine hydroxymethyltransferase; eNOS; endo
Keywords: BTX; bungarotoxin; CME; clathrin-mediated endocytosis; ER stress; endoplasmic reticulum stress; ERAD; endoplasmic reticulum-associated degradation; MβCD; methyl-beta-cyclodextrin; MFI; mean fluorescence intensity; AChR; acetylcholine receptor; ATF6; acti
Keywords: Abl; Abelson murine leukemia viral oncogene homolog 1; Akt/PKB; protein kinase B; bZIP; basic leucine zipper; C/EBP-β; CCAAT-enhancer-binding protein β; Egr; early growth response; ER; estrogen receptor; Fox; Forkhead box protein; hGH; human growth horm
Keywords: Protease inhibitor; Placenta; XBP1; Endoplasmic reticulum stress; Adverse effect; Mother-to-child transmission
Keywords: ER; endoplasmic reticulum; UPR; unfolded protein response; AD; Alzheimer's disease; APP; amyloid precursor protein; GRP78/BiP; chaperone glucose-regulated protein 78; PERK; protein kinase RNA (PKR)-like ER kinase; ATF6; activating transcription factor 6;
Keywords: ACh; acetylcholine; ATGL; adipose triglyceride lipase; AKO; adipose triglyceride lipase knockout; BIP; binding immunoglobulin protein; BK; bradykinin; BSA; bovine serum albumin; CD31; cluster of differentiation 31; CL; chemiluminescence; CPP; coronary per
Keywords: ASK1; apoptosis signal-regulating kinase 1; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; Bcl-2; B-cell lymphoma 2; BiP; binding immunoglobulin protein; bZIP; basic leucine zipper; CDK; cyclin-dependent kinase; CDKI; CD
Keywords: AP-1; activator protein-1; BLNK; B cell linker protein; BTK; Bruton's tyrosine kinase; CCT; choline cytidylyltransferase; CDP-choline; cytidine diphosphocholine; CEPT1; choline/ethanolamine phosphotransferase 1; Cer; ceramide; CK; choline kinase; CPT1; ch
Keywords: AEC; alveolar epithelial cell; AT2; alveolar epithelial type II; AM; alveolar macrophage; ARE; antioxidant response element; BALF; bronchoalveolar lavage fluid; JNK; c-Jun N-terminal kinase; EGFR; epidermal growth factor receptor; ECM; extracellular matri
Marine bis-γ-pyrone polypropionates of onchidione family and their effects on the XBP1 gene expression
Keywords: Pulmonate; Polypropionates; Absolute configuration; XBP1;
Endoplasmic reticulum stress in bipolar disorder? - BiP and CHOP gene expression- and XBP1 splicing analysis in peripheral blood
Keywords: Bipolar Disorder; Endoplasmic Reticulum; ER stress; Unfolded Protein Response; BiP; GRP78; CHOP; XBP1;
Designing an effective drug combination for ER stress loading in cancer therapy using a real-time monitoring system
Keywords: ER stress; ERAI-Venus; XBP1; Proteasome; Autophagy; Aggresom; Breast cancer; Cancer;
Targeting the enhanced ER stress response in Marinesco-Sjögren syndrome
Keywords: Marinesco-Sjögren syndrome; ER stress; Lymphoblastoid cell line; Tunicamycin; Apoptosis; Tauroursodeoxycholic acid; 4-PBA; sodium phenylbutyrate; ATF6α; activating transcription factor 6α; CASP3; caspase-3; DEXA; dexamethasone; EBV; Epstein-Barr virus;
Real-Time and Non-invasive Monitoring of the Activation of the IRE1α-XBP1 Pathway in Individuals with Hemodynamic Impairment
Keywords: Endoplasmic reticulum stress; Unfolded protein response; Acute kidney injury; Cardiopulmonary bypass; XBP1; IRE1α;
RACK1 upregulation induces neuroprotection by activating the IRE1-XBP1 signaling pathway following traumatic brain injury in rats
Keywords: RACK1; IRE1; XBP1; Neuroprotection; Secondary brain injury; Traumatic brain injury;
Small molecule PGC-1α1 protein stabilizers induce adipocyte Ucp1 expression and uncoupled mitochondrial respiration
Keywords: Small molecule screening; PGC-1a; PGC-1alpha; PGC-1alpha1; Protein stabilization; UCP1; Mitochondrial respiration; Brown adipose tissue; C/EBP; CCAAT-enhancer-binding proteins; FCCP; carbonyl cyanide-4-(trifluoromethoxy)phenylhydrazone; HEK; human embryon
Adipocyte Xbp1s overexpression drives uridine production and reduces obesity
Keywords: Obesity; Xbp1; ER stress; UPR; Pyrimidine; Uridine; CAD;
miRNA meets plasma cells “How tiny RNAs control antibody responses”
Keywords: PC; plasma cell; PB; plasmablast; GC; germinal center; SHM; somatic hypermutation; CSR; class switch recombination; AID; activation-induced cytidine deaminase; Ig; immunoglobulin; Blimp-1; B-lymphocyte-induced maturation protein 1; DGCR8; DiGeorge syndrom
XBP1 activation enhances MANF expression via binding to endoplasmic reticulum stress response elements within MANF promoter region in hepatitis B
Keywords: MANF; mesencephalic astrocyte-derived neurotrophic factor; XBP1; X-box binding protein-1; TM; tunicamycin; ERSE; ER stress-responsive elements; UPR; unfolded protein response; IRE1α; inositol-requiring 1α; LPS; lipopolysaccharide; Mesencephalic astrocyt
The unknown face of IRE1α - Beyond ER stress
Keywords: ER; endoplasmic reticulum; UPR; unfolded protein response; IRE1; inositol requiring kinase enzyme 1; XBP1; x-box binding protein 1; bZIP; basic leucine zipper domain; HAC1; histone acetyl transferase 1; ATF; activating transcription factor; RIDD; regulate
Involvement of glucose-regulated protein 78 and spliced X-box binding protein 1 in the protective effect of gliclazide in diabetic nephropathy
Keywords: Diabetic nephropathy; ER stress; GRP78; XBP1; Gliclazide;
Fasting exacerbates hepatic growth differentiation factor 15 to promote fatty acid β-oxidation and ketogenesis via activating XBP1 signaling in liver
Keywords: GDF15; growth differentiation factor 15; UPR; unfolded protein response; IRE1α; inositol requiring enzyme 1 alpha; XBP1; x-box binding protein 1; STZ; streptozotocin; ChIP; chromatin immunoprecipitation; ERSE; ER stress-response element; Ppara; peroxisom
Novel oxindole derivatives prevent oxidative stress-induced cell death in mouse hippocampal HT22â¯cells
Keywords: ER stress; Ferroptosis; Oxidative stress; Oxindole; Oxytosis; Rasagiline; ATF6; activated transcription factor 6; ARE; antioxidant response element; DMEM; Dulbecco's modified Eagle's medium; ER; endoplasmic reticulum; Grp78; 78-kDa glucose-regulated prote
Portal myofibroblasts are sensitive to CCN-mediated endoplasmic reticulum stress-related apoptosis with potential to attenuate biliary fibrogenesis
Keywords: CCN proteins; ER stress; Unfolded protein response; Matricellular proteins; Portal myofibroblasts; TUDCA; α-SMA; α-smooth muscle actin; ATF6; activating transcription factor 6; BDL; bile duct ligation; eIF2α; eukaryotic translation initiation factor 2Î
Endoplasmic reticulum stress-dependent ROS production mediates synovial myofibroblastic differentiation in the immobilization-induced rat knee joint contracture model
Keywords: ATF6; activating transcription factor 6; ATF6α; activating transcription factor 6 alpha; CHOP; C/EBP homology protein; DMSO; dimethylsulphoxide; DCHF-DA; 2â²,7â²-dichlorofluorescein diacetate; DPI; diphenyleneiodonium; ER; endoplasmic reticulum; GAPDH;
Axonal Activation of the Unfolded Protein Response Promotes Axonal Regeneration Following Peripheral Nerve Injury
Keywords: 2-APB; 2-aminoethoxydiphenyl borate; AD; Alzheimer's disease; ATF6; activating transcription factor 6; BiP; binding immunoglobulin protein; BSA; bovine serum albumin; CHOP; CCAAT enhancer binding protein homologous protein; DRG; dorsal root ganglion; ED
Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2)
Keywords: NASH; Nrf2; TBE-31; ACACA; acetyl-CoA carboxylase alpha; ACLY; ATP citrate lyase; ACOT7; acetyl-CoA thioesterase 7; ACOX2; acetyl-CoA oxidase 2; ADRP; adipose differentiation-related protein; AP-1; activator protein 1; ApoB; apolipoprotein B; ATF4; activa
TLR7-mediated activation of XBP1 correlates with the IFNα production in humans
Keywords: XBP1; Toll-like receptor 7; Interferon α;
Development of an XBP1 agonist, HLJ2, as a potential therapeutic agent for ulcerative colitis
Keywords: Ulcerative colitis; XBP1; Intestinal flora; Intestinal mucosa; Cytokines;
Downregulation of TRB3 protects neurons against apoptosis induced by global cerebral ischemia and reperfusion injury in rats
Keywords: ANOVA; analysis of variance; ATF4; transcription factor 4; Bad; Bcl-2-associated death protein; BCA; bicinchoninic acid assay; CA; cornu ammonis; CHOP; CCAAT/enhancer-binding protein (C/EBP) homologous protein; DAB; diaminobenzidine; DAPI; 4,6,diamidino-2
Modulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseases
Keywords: α-SYN; alpha synuclein; β-TrCP; β-transducin repeat containing E3 ubiquitin protein ligase; Aβ; amyloid beta; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; AMPK; AMP-activated protein kinase; ARE; antioxidant response element; ASK1; apo
Regular articleAmyloid-β42 clearance and neuroprotection mediated by X-box binding protein 1 signaling decline with aging in the Drosophila brain
Keywords: Alzheimer's disease; Amyloid β; Unfolded protein response; XBP1; Neurodegeneration; Drosophila;
Osteogenesis imperfecta: new genes reveal novel mechanisms in bone dysplasia
Keywords: ADAMTS; A disintegrin and metalloprotease with thrombospondin motifs; AR-OI; autosomal recessive osteogenesis imperfecta; ATF6; activating transcription factor 6; ATGL; adipose triglyceride lipase; BiP; binding immunoglobulin protein; BMDD; bone mineraliz
Both nitric oxide and nitrite prevent homocysteine-induced endoplasmic reticulum stress and subsequent apoptosis via cGMP-dependent pathway in neuronal cells
Keywords: Nitric oxide; Nitrite; Endoplasmic reticulum stress; Apoptosis; cGMP; Neuronal cells; 7-AAD; 7-aminoactinomycin D; AD; Alzheimer's disease; ATF6; activating transcription factor 6; Br-cGMP; 8-bromo-cyclic cyclic guanosine 3â²,5â²-monophosphate; cGMP; cy
The role of barrier function, autophagy, and cytokines in maintaining intestinal homeostasis
Keywords: IEC; intestinal epithelial cell; TJ; tight junctions; IBD; inflammatory bowel disease; ER; endoplasmic reticulum; UPR; unfolded protein response; CD; Crohn's disease; IL; Interleukin; NOD2; nucleotide-binding oligomerization domain-containing protein
Molecular characterization and expression pattern of X box-binding protein-1 (XBP1) in common carp (Cyprinus carpio L.): Indications for a role of XBP1 in antibacterial and antiviral immunity
Keywords: Common carp (Cyprinus carpio L.); XBP1; Innate immunity; Real-time RT-PCR;
Metabolic syndrome enhances endoplasmic reticulum, oxidative stress and leukocyte-endothelium interactions in PCOS
Keywords: PCOS; polycystic ovary syndrome; IR; insulin resistance; ER; endoplasmic reticulum; HOMA; homeostatic model assessment; ROS; reactive oxygen species; ICAM-1; intercellular adhesion molecule 1; VCAM-1; vascular cell adhesion molecule 1; IL-6; interleukin 6
Ageing sensitized by iPLA2β deficiency induces liver fibrosis and intestinal atrophy involving suppression of homeostatic genes and alteration of intestinal lipids and bile acids
Keywords: ACC; acetyl-CoA carboxylase; ATF6; activating transcription factor6; AB-PAS; alcian blue-periodic acidschiff; ACC; acetyl-CoA carboxylase; ACSL; long-chain acyl-CoA synthetase; Bad; Bcl-2-associated death promoter; Bax; Bcl-2-like protein 4; Bcl-2; B-cell