NAD-binding mode and the significance of intersubunit contact revealed by the crystal structure of Mycobacterium tuberculosis NAD kinase-NAD complex Fulltext Access 9 Pages 2005
The involvement of key DNA repair pathways in the formation of chromosome rearrangements in embryonic stem cells Fulltext Access 9 Pages 2005
Characteristic analysis of the ampC gene encoding β-lactamase from Photobacterium phosphoreum Fulltext Access 9 Pages 2005
Crosstalk between cancer cells and bone microenvironment in bone metastasis Fulltext Access 9 Pages 2005
Human monoamine oxidase is inhibited by tobacco smoke: β-carboline alkaloids act as potent and reversible inhibitors Fulltext Access 9 Pages 2005
Functional preservation of duplicated pair for RSVS III gene in the REST locus of rat 3q42 Fulltext Access 9 Pages 2005
Nanoscale orientation and lateral organization of chimeric metal-binding green fluorescent protein on lipid membrane determined by epifluorescence and atomic force microscopy Fulltext Access 9 Pages 2005
cGMP-dependent phosphorylation and degradation of myristoylated alanine-rich C-kinase substrate Fulltext Access 9 Pages 2005
Downregulation of β1,4-galactosyltransferase 1 inhibits CDK11p58-mediated apoptosis induced by cycloheximide Fulltext Access 9 Pages 2005
In vitro neuronal differentiation of cultured human embryonic germ cells Fulltext Access 9 Pages 2005
Heterogeneity in premature senescence by oxidative stress correlates with differential DNA damage during the cell cycle Fulltext Access 9 Pages 2005
Organic solvent extracted EmrE solubilized in dodecyl maltoside is monomeric and binds drug ligand Fulltext Access 9 Pages 2005
Cloning and characterization of a small-size peptide Zfra that regulates the cytotoxic function of tumor necrosis factor by interacting with JNK1 Fulltext Access 9 Pages 2005
Amiloride and the regulation of NF-κB: an unsung crosstalk and missing link between fluid dynamics and oxidative stress-related inflammation-controversy or pseudo-controversy? Fulltext Access 9 Pages 2005
Tumor necrosis factor (TNF) interferes with insulin signaling through the p55 TNF receptor death domain Fulltext Access 9 Pages 2005
Increase of smooth muscle cell migration and of intimal hyperplasia in mice lacking the α/β hydrolase domain containing 2 gene Fulltext Access 9 Pages 2005
Phorbol ester phorbol-12-myristate-13-acetate promotes anchorage-independent growth and survival of melanomas through MEK-independent activation of ERK1/2 Fulltext Access 9 Pages 2005
Plasminogen/plasmin regulates c-fos and egr-1 expression via the MEK/ERK pathway Fulltext Access 9 Pages 2005
Involvement of specific proteins (Sp1/Sp3) and nuclear factor Y in basal transcription of the distal promoter of the rat pyruvate carboxylase gene in β-cells Fulltext Access 9 Pages 2005
Engineering and characterization of a divalent single-chain Fv angiotensin II fusion construct of the monoclonal antibody CC49 Fulltext Access 9 Pages 2005
Solution structure of humanin, a peptide against Alzheimer's disease-related neurotoxicity Fulltext Access 9 Pages 2005
Substrate specificity of the Saccharomyces cerevisiae Mus81-Mms4 endonuclease Fulltext Access 9 Pages 2005
Cathepsin B and tumor proteolysis: contribution of the tumor microenvironment Fulltext Access 9 Pages 2005
Tissue homeostasis and the control of the neoplastic phenotype in epithelial cancers Fulltext Access 9 Pages 2005
In vitro and in vivo imaging of cell migration: Two interdepending methods to unravel metastasis formation Fulltext Access 9 Pages 2005
3D-extravasation model - selection of highly motile and metastatic cancer cells Fulltext Access 9 Pages 2005
ETV6-NTRK3: a chimeric protein tyrosine kinase with transformation activity in multiple cell lineages Fulltext Access 9 Pages 2005
Understanding mesenchymal cancer: the liposarcoma-associated FUS-DDIT3 fusion gene as a model Fulltext Access 9 Pages 2005
Emergence and prevention of resistance against small molecule inhibitors Fulltext Access 9 Pages 2005
Selective evolutionary pressure from the tissue microenvironment drives tumor progression Fulltext Access 9 Pages 2005
The yeast MSH1 gene is not involved in DNA repair or recombination during meiosis Fulltext Access 9 Pages 2005
n-Alkane and clofibrate, a peroxisome proliferator, activate transcription of ALK2 gene encoding cytochrome P450alk2 through distinct cis-acting promoter elements in Candida maltosa Fulltext Access 9 Pages 2005
Cellular response to horizontally transferred DNA in Escherichia coli is tuned by DNA repair systems Fulltext Access 9 Pages 2005
Repair of the three main types of bipyrimidine DNA photoproducts in human keratinocytes exposed to UVB and UVA radiations Fulltext Access 9 Pages 2005
Cisplatin induces DNA double-strand break formation in Escherichia coli dam mutants Fulltext Access 9 Pages 2005
Mutability of DNA polymerase I: Implications for the creation of mutant DNA polymerases Fulltext Access 9 Pages 2005
Mono-allelic POLG expression resulting from nonsense-mediated decay and alternative splicing in a patient with Alpers syndrome Fulltext Access 9 Pages 2005
XP-A cells complemented with Arg228Gln and Val234Leu polymorphic XPA alleles repair BPDE-induced DNA damage better than cells complemented with the wild type allele Fulltext Access 9 Pages 2005
Mismatch repair protein Msh2 contributes to UVB-induced cell cycle arrest in epidermal and cultured mouse keratinocytes Fulltext Access 9 Pages 2005
DNA glycosylase activities for thymine residues oxidized in the methyl group are functions of the hNEIL1 and hNTH1 enzymes in human cells Fulltext Access 9 Pages 2005
The Elg1 replication factor C-like complex: a novel guardian of genome stability Fulltext Access 9 Pages 2005
DDB2, the xeroderma pigmentosum group E gene product, is directly ubiquitylated by Cullin 4A-based ubiquitin ligase complex Fulltext Access 9 Pages 2005
Circadian expression of clock genes and clock-controlled genes in the rat retina Fulltext Access 9 Pages 2005
Evaluation of insulin resistance linkage to rat chromosome 4 in SHR of a Japanese colony Fulltext Access 9 Pages 2005
Novel TLR4-antagonizing peptides inhibit LPS-induced release of inflammatory mediators by monocytes Fulltext Access 9 Pages 2005
Identification of ASK1, MKK4, JNK, c-Jun, and caspase-3 as a signaling cascade involved in cadmium-induced neuronal cell apoptosis Fulltext Access 9 Pages 2005
Nondenaturing solubilization of β2 microglobulin from inclusion bodies by l-arginine Fulltext Access 9 Pages 2005
Carvedilol effectively blocks oxidative stress-mediated downregulation of sarcoplasmic reticulum Ca2+-ATPase 2 gene transcription through modification of Sp1 binding Fulltext Access 9 Pages 2005
Suppression of PI3K/mTOR pathway rescues LLC cells from cell death induced by hypoxia Fulltext Access 9 Pages 2005
Characterization of human NIPK (TRB3, SKIP3) gene activation in stressful conditions Fulltext Access 9 Pages 2005
Raft-like membrane domains contain enzymatic activities involved in the synthesis of mammalian glycosylphosphatidylinositol anchor intermediates Fulltext Access 9 Pages 2005
Epithelial differentiation of human adipose tissue-derived adult stem cells Fulltext Access 9 Pages 2005
Caveolin-2 regulation of the cell cycle in response to insulin in Hirc-B fibroblast cells Fulltext Access 9 Pages 2005
Block of inactivation-deficient cardiac Na+ channels by acetyl-KIFMK-amide Fulltext Access 9 Pages 2005
Molecular analysis of the interaction between the intracellular loops of the human serotonin receptor type 6 (5-HT6) and the α subunit of GS protein Fulltext Access 9 Pages 2005
A boundary for histone acetylation allows distinct expression patterns of the Ad4BP/SF-1 and GCNF loci in adrenal cortex cells Fulltext Access 9 Pages 2005
The tumor suppressor DAL-1/4.1B modulates protein arginine N-methyltransferase 5 activity in a substrate-specific manner Fulltext Access 9 Pages 2005
Diphtheria toxin translocation across cellular membranes is regulated by sphingolipids Fulltext Access 9 Pages 2005
Topological analysis of GtrA and GtrB proteins encoded by the serotype-converting cassette of Shigella flexneri Fulltext Access 9 Pages 2005
Transcriptome analysis in the midgut of the earthworm (Eisenia andrei) using expressed sequence tags Fulltext Access 9 Pages 2005
Cytokeratin 8 associates with the external leaflet of plasma membranes in tumour cells Fulltext Access 9 Pages 2005
WICH, a member of WASP-interacting protein family, cross-links actin filaments Fulltext Access 9 Pages 2005
Transient strong reduction of PTEN expression by specific RNAi induces loss of adhesion of the cells Fulltext Access 9 Pages 2005
Identification of a novel testis-specific gene mtLR1, which is expressed at specific stages of mouse spermatogenesis Fulltext Access 9 Pages 2005
Neuropeptide substance P stimulates the formation of osteoclasts via synovial fibroblastic cells Fulltext Access 9 Pages 2005
The high-affinity cAMP phosphodiesterase of Saccharomyces cerevisiae is the major determinant of cAMP levels in stationary phase: involvement of different branches of the Ras-cyclic AMP pathway in stress responses Fulltext Access 9 Pages 2005
Transcriptomic fingerprinting of bone marrow-derived hepatic β2mâ/Thy-1+ stem cells Fulltext Access 9 Pages 2005
Small interfering RNA-induced suppression of ERCC1 enhances sensitivity of human cancer cells to cisplatin Fulltext Access 9 Pages 2005
Proteomic analysis revealed a novel synaptic proline-rich membrane protein (PRR7) associated with PSD-95 and NMDA receptor Fulltext Access 9 Pages 2005
Interaction analysis of chimeric metal-binding green fluorescent protein and artificial solid-supported lipid membrane by quartz crystal microbalance and atomic force microscopy Fulltext Access 9 Pages 2005
The glucosyl-1-phosphate transferase WchA (Cap8E) primes the capsular polysaccharide repeat unit biosynthesis of Streptococcus pneumoniae serotype 8 Fulltext Access 9 Pages 2005
Identification of novel electroconvulsive shock-induced and activity-dependent genes in the rat brain Fulltext Access 9 Pages 2005
Corticotropin-releasing hormone activates protein kinase C in an isoenzyme-specific manner Fulltext Access 9 Pages 2005
Ectopic overexpression of adipogenic transcription factors induces transdifferentiation of MC3T3-E1 osteoblasts Fulltext Access 9 Pages 2005
dsRNA formed as an intermediate during Coxsackievirus infection does not induce NO production in a β-cell line with or without addition of IFN-γ Fulltext Access 9 Pages 2005
Increased p21ras activity in human fibroblasts transduced with survivin enhances cell proliferation Fulltext Access 9 Pages 2005
Suppressor of cytokine signaling 1 suppresses muscle differentiation through modulation of IGF-I receptor signal transduction Fulltext Access 9 Pages 2005
Phosphorylated IκBα is a component of Lewy body of Parkinson's disease Fulltext Access 9 Pages 2005
Specific inactivation of cysteine protease-type cathepsin by singlet oxygen generated from naphthalene endoperoxides Fulltext Access 9 Pages 2005
Expression profiles of mouse dendritic cell sarcoma are similar to those of hematopoietic stem cells or progenitors by clustering and principal component analyses Fulltext Access 9 Pages 2005
Enhanced expression of PDX-1 and Ngn3 by exendin-4 during β cell regeneration in STZ-treated mice Fulltext Access 9 Pages 2005
PKCε-PKD1 signaling complex at Z-discs plays a pivotal role in the cardiac hypertrophy induced by G-protein coupling receptor agonists Fulltext Access 9 Pages 2005
Evidence that insulin secretion influences SNAP-25 through proteasomal activation Fulltext Access 9 Pages 2005
Simvastatin triggers mitochondria-induced Ca2+ signaling alteration in skeletal muscle Fulltext Access 9 Pages 2005