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Daneshyari Molecular Medicine Journas Latest Articles

Molecular Medicine Research Articles

MicroRNA expression changes during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal, a product of lipid peroxidation
Fulltext Access 7 Pages 2009
Homer1 regulates the susceptibility to TRAIL
Fulltext Access 7 Pages 2009
Ornithine decarboxylase regulates the activity and localization of rhoA via polyamination
Fulltext Access 7 Pages 2009
Superoxide dismutase is regulated by LAMMER kinase in Drosophila and human cells
Fulltext Access 7 Pages 2009
Hepatocyte growth factor protects hepatocytes against oxidative injury induced by ethanol metabolism
Fulltext Access 7 Pages 2009
Role of IL-23 in mobilization of immunoregulatory nitric oxide- or superoxide-producing Gr-1+ cells from bone marrow
Fulltext Access 7 Pages 2009
Automated method for the direct analysis of 8-oxo-guanosine and 8-oxo-2′-deoxyguanosine in human urine using ultraperformance liquid chromatography and tandem mass spectrometry
Fulltext Access 7 Pages 2009
Dietary supplementation of ω-3 fatty acid-containing fish oil suppresses F2-isoprostanes but enhances inflammatory cytokine response in a mouse model of ovalbumin-induced allergic lung inflammation
Fulltext Access 7 Pages 2009
Attenuation of oxidant-induced muscle insulin resistance and p38 MAPK by exercise training
Fulltext Access 7 Pages 2009
Ineffective GSH regeneration enhances G6PD-knockdown Hep G2 cell sensitivity to diamide-induced oxidative damage
Fulltext Access 7 Pages 2009
Acyl-CoA-induced generation of reactive oxygen species in mitochondrial preparations is due to the presence of peroxisomes
Fulltext Access 7 Pages 2009
The dual function of nitrite under stomach conditions is modulated by reducing compounds
Fulltext Access 7 Pages 2009
Amplifying the fluorescence of bilirubin enables the real-time detection of heme oxygenase activity
Fulltext Access 7 Pages 2009
Intracellular trafficking of Notch receptors and ligands
Fulltext Access 7 Pages 2009
Sex-dependent differences in aged rat brain mitochondrial function and oxidative stress
Fulltext Access 7 Pages 2009
Control of hypoxia-induced tumor cell adhesion by cytophilic human catalase
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Effect of T3 on metabolic response and oxidative stress in skeletal muscle from sedentary and trained rats
Fulltext Access 7 Pages 2009
A recombinant MnSOD is radioprotective for normal cells and radiosensitizing for tumor cells
Fulltext Access 7 Pages 2009
Mitochondrial complex I dysfunction in rat heart with aging: critical role of reactive oxygen species and cardiolipin
Fulltext Access 7 Pages 2009
Synthesis and pharmacological evaluation of novel N-alkyl/aryl substituted thiazolidinone arecoline analogues as muscarinic receptor 1 agonist in Alzheimer's dementia models
Fulltext Access 7 Pages 2009
Captopril and 6-mercaptopurine: Whose SH possesses higher antioxidant ability?
Fulltext Access 7 Pages 2009
Novel cyclic-imide peptidomimetics as aminopeptidase N inhibitors. Design, chemistry and activity evaluation. Part I
Fulltext Access 7 Pages 2009
Synthesis, characterization and antibacterial activity of some triazole Mannich bases carrying diphenylsulfone moieties
Fulltext Access 7 Pages 2009
Synthesis and evaluation of the antioxidant and anti-inflammatory activity of novel coumarin-3-aminoamides and their alpha-lipoic acid adducts
Fulltext Access 7 Pages 2009
Molecular orbital differentiation of agonist and antagonist activity in the GlycineB-iGluR-NMDA receptor
Fulltext Access 7 Pages 2009
Evaluation of 99mTc(CO)5I as a potential lung perfusion agent
Fulltext Access 7 Pages 2009
Development and validation of 2-deoxy-2-chloro-d-glucose impurity analysis in [18F]FDG by three potential-time waveforms of high-performance liquid chromatography/pulsed amperometric detection
Fulltext Access 7 Pages 2009
Comparative study of cellular kinetics of reporter probe [131I]FIAU in neonatal cardiac myocytes after transfer of HSV1-tk reporter gene with two vectors
Fulltext Access 7 Pages 2009
Clinical evaluation of antimicrobial peptide [99mTc/Tricine/HYNIC0]ubiquicidin 29-41 as a human-specific infection imaging agent
Fulltext Access 7 Pages 2009
Expressions of glucose transporter Types 1 and 3 and hexokinase-II in diffuse large B-cell lymphoma and other B-cell non-Hodgkin's lymphomas
Fulltext Access 7 Pages 2009
Measurement of glucose metabolism in rat spinal cord slices with dynamic positron autoradiography
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3′-Deoxy-3′-[18F]fluorothymidine (FLT) uptake in breast cancer cells as a measure of proliferation after doxorubicin and docetaxel treatment
Fulltext Access 7 Pages 2009
Fluorine-18 labeling and biodistribution studies on peroxisome proliferator-activated receptor-γ ligands: potential positron emission tomography imaging agents
Fulltext Access 7 Pages 2009
Development of [90Y]DOTA-conjugated bisphosphonate for treatment of painful bone metastases
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Evaluation of [11C]laniquidar as a tracer of P-glycoprotein: radiosynthesis and biodistribution in rats
Fulltext Access 7 Pages 2009
Multipoint analysis of reduced 125I-meta-iodobenzylguanidine uptake and norepinephrine turnover in the hearts of mice with 1-methyl-4-phenyl-1,2,3,6-tetrahydroxypyridine-induced parkinsonism
Fulltext Access 7 Pages 2009
Dual-isotope single-photon emission computed tomography for dopamine and serotonin transporters in normal and parkinsonian monkey brains
Fulltext Access 7 Pages 2009
True radiotracers: Cu-64 targeting vectors based upon bombesin peptide
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Synthesis and antitumor activity of optically active thiourea and their 2-aminobenzothiazole derivatives: A novel class of anticancer agents
Fulltext Access 7 Pages 2009
Uptake of 99mTc-labeled chondroitin sulfate by chondrocytes and cartilage: a promising agent for imaging of cartilage degeneration?
Fulltext Access 7 Pages 2009
Synthesis and biodistribution of lipophilic and monocationic gallium radiopharmaceuticals derived from N,N′-bis(3-aminopropyl)-N,N′-dimethylethylenediamine: potential agents for PET myocardial imaging with 68Ga
Fulltext Access 7 Pages 2009
The effect of PPAR-γ agonist on 18F-FDG uptake in tumor and macrophages and tumor cells
Fulltext Access 7 Pages 2009
Validation of an 18F-labeled biphenylalkyne as a positron emission tomography imaging agent for β-amyloid plaques
Fulltext Access 7 Pages 2009
Development of microwave-based automated nucleophilic [18F]fluorination system and its application to the production of [18F]flumazenil
Fulltext Access 7 Pages 2009
Radiolabeling of trastuzumab with 177Lu via DOTA, a new radiopharmaceutical for radioimmunotherapy of breast cancer
Fulltext Access 7 Pages 2009
In vivo examination of 188Re(I)-tricarbonyl-labeled trastuzumab to target HER2-overexpressing breast cancer
Fulltext Access 7 Pages 2009
Sailing with the Wnt: Charting the Wnt processing and secretion route
Fulltext Access 7 Pages 2009
Deletion of the p107/p130-binding domain of Mip130/LIN-9 bypasses the requirement for CDK4 activity for the dissociation of Mip130/LIN-9 from p107/p130-E2F4 complex
Fulltext Access 7 Pages 2009
Tubulin cofactor B regulates microtubule densities during microglia transition to the reactive states
Fulltext Access 7 Pages 2009
Molecular assemblies and membrane domains in multivesicular endosome dynamics
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Synthesis and in vitro cysticidal activity of new benzimidazole derivatives
Fulltext Access 7 Pages 2009
Synthesis and biological evaluation of novel luteolin derivatives as antibacterial agents
Fulltext Access 7 Pages 2009
Cytotoxic, antioxidant activities and structure activity relationship of some newly synthesized terpenoidal oxaliplatin analogs
Fulltext Access 7 Pages 2009
Targeting cancer cells with biotin–dendrimer conjugates
Fulltext Access 7 Pages 2009
Synthesis, analgesic, anti-inflammatory and antimicrobial studies of 2,4-dichloro-5-fluorophenyl containing thiazolotriazoles
Fulltext Access 7 Pages 2009
Synthesis and biological evaluation of cytotoxic properties of stilbene-based resveratrol analogs
Fulltext Access 7 Pages 2009
Lowering of 5-nitroimidazole's mutagenicity: Towards optimal antiparasitic pharmacophore
Fulltext Access 7 Pages 2009
QSAR studies for diarylpyrimidines against HIV-1 reverse transcriptase wild-type and mutant strains
Fulltext Access 7 Pages 2009
Synthesis and antimicrobial activities of some new triazolothiadiazoles bearing 4-methylthiobenzyl moiety
Fulltext Access 7 Pages 2009
Application of phosphonyl carbanions to highly regioselective synthesis of some diazaphospholes and pyrazolinyl phosphonates
Fulltext Access 7 Pages 2009
1,4-Diazepanes derived from (S)-serine – Homopiperazines with improved σ1 (sigma) receptor affinity and selectivity
Fulltext Access 7 Pages 2009
Design, synthesis and structure–activity relationships of antiproliferative 1,3-disubstituted urea derivatives
Fulltext Access 7 Pages 2009
Anti-HIV evaluation of benzo[d]isothiazole hydrazones
Fulltext Access 7 Pages 2009
Synthesis, antiviral activity, and stability of nucleoside analogs containing tricyclic bases
Fulltext Access 7 Pages 2009
Convenient one-pot synthesis of novel 2-substituted benzimidazoles, tetrahydrobenzimidazoles and imidazoles and evaluation of their in vitro antibacterial and antifungal activities
Fulltext Access 7 Pages 2009
Synthesis and pharmacological evaluation of a novel series of 5-(substituted)aryl-3-(3-coumarinyl)-1-phenyl-2-pyrazolines as novel anti-inflammatory and analgesic agents
Fulltext Access 7 Pages 2009
Synthesis and characterization of new Pt(II) and Pd(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone: Cytotoxic activity evaluation of Cd(II), Zn(II), Ni(II), Pt(II) and Pd(II) complexes with heteroaromatic selenosemicarbazones
Fulltext Access 7 Pages 2009
First-principle, structure-based prediction of hepatic metabolic clearance values in human
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Hybrid molecules between benzenesulfonamides and active antimicrobial benzo[d]isothiazol-3-ones
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Synthesis and antioxidant potential of novel synthetic benzophenone analogues
Fulltext Access 7 Pages 2009
Preparation of spermine conjugates with acidic retinoids with potent ribonuclease P inhibitory activity
Fulltext Access 7 Pages 2009
Synthesis and pharmacological evaluation of 2(3H)-furanones and 2(3H)-pyrrolones, combining analgesic and anti-inflammatory properties with reduced gastrointestinal toxicity and lipid peroxidation
Fulltext Access 7 Pages 2009
Prediction of milk/plasma concentration ratios of drugs and environmental pollutants
Fulltext Access 7 Pages 2009
Aroylpropionic acid based 2,5-disubstituted-1,3,4-oxadiazoles: Synthesis and their anti-inflammatory and analgesic activities
Fulltext Access 7 Pages 2009
Classification models for CYP450 3A4 inhibitors and non-inhibitors
Fulltext Access 7 Pages 2009
CoMFA, LeapFrog and blind docking studies on sulfonanilide derivatives acting as selective aromatase expression regulators
Fulltext Access 7 Pages 2009
Juglone derivatives as antitubercular agents: A rationale for the activity profile
Fulltext Access 7 Pages 2009
Synthesis, pharmacological and in silico evaluation of 1-(4-di-hydroxy-3,5-dioxa-4-borabicyclo[4.4.0]deca-7,9,11-trien-9-yl)-2-(tert-butylamino)ethanol, a compound designed to act as a β2 adrenoceptor agonist
Fulltext Access 7 Pages 2009
Synthesis and biological evaluation of a novel series of 1,5-benzothiazepine derivatives as potential antimicrobial agents
Fulltext Access 7 Pages 2009
Fenbufen based 3-[5-(substituted aryl)-1,3,4-oxadiazol-2-yl]-1-(biphenyl-4-yl)propan-1-ones as safer antiinflammatory and analgesic agents
Fulltext Access 7 Pages 2009
Antiviral evaluation of N-amino-1,2,3-triazoles against Cantagalo virus replication in cell culture
Fulltext Access 7 Pages 2009
Synthesis and cytotoxic activity of α-santonin derivatives
Fulltext Access 7 Pages 2009
Synthesis of new acridines and hydrazones derived from cyclic β-diketone for cytotoxic and antiviral evaluation
Fulltext Access 7 Pages 2009
Synthesis of a series of N6-substituted adenosines with activity against trypanosomatid parasites
Fulltext Access 7 Pages 2009
Development of QSAR models for predicting hepatocarcinogenic toxicity of chemicals
Fulltext Access 7 Pages 2009
Knowledge based identification of MAO-B selective inhibitors using pharmacophore and structure based virtual screening models
Fulltext Access 7 Pages 2009
Multivariate QSAR study of 4,5-dihydroxypyrimidine carboxamides as HIV-1 integrase inhibitors
Fulltext Access 7 Pages 2009
Palladium(II) complexes with R2edda-derived ligands. Part II. Synthesis, characterization and in vitro antitumoral studies of R2eddip esters and palladium(II) complexes
Fulltext Access 7 Pages 2009
Synthesis, antimicrobial and antiviral evaluation of substituted imidazole derivatives
Fulltext Access 7 Pages 2009
Design, synthesis and anticancer evaluation of novel tetrahydroquinoline derivatives containing sulfonamide moiety
Fulltext Access 7 Pages 2009
Novel Biginelli dihydropyrimidines with potential anticancer activity: A parallel synthesis and CoMSIA study
Fulltext Access 7 Pages 2009
Blue CrO5 assay: A novel spectrophotometric method for the evaluation of the antioxidant and oxidant capacity of various biological substances
Fulltext Access 7 Pages 2009
An efficient steroid pharmacophore-based strategy to identify new aromatase inhibitors
Fulltext Access 7 Pages 2009
Fluorescence spectroscopic investigation of the interaction between chloramphenicol and lysozyme
Fulltext Access 7 Pages 2009
Synthesis and in vitro antibacterial activity of 7-(4-alkoxyimino-3-amino-3-methylpiperidin-1-yl)fluoroquinolone derivatives
Fulltext Access 7 Pages 2009
Predicting the activity of drugs for a group of imidazopyridine anticoccidial compounds
Fulltext Access 7 Pages 2009
Synthesis and characterization of rhenium and technetium-99m tricarbonyl complexes bearing the 4-[3-bromophenyl]quinazoline moiety as a biomarker for EGFR-TK imaging
Fulltext Access 7 Pages 2009
Novel 4-(morpholin-4-yl)-N′-(arylidene)benzohydrazides: Synthesis, antimycobacterial activity and QSAR investigations
Fulltext Access 7 Pages 2009
In vitro and in vivo anticancer activity of 2-deacetoxytaxinine J and synthesis of novel taxoids and their in vitro anticancer activity
Fulltext Access 7 Pages 2009
Natural tanshinone-like heterocyclic-fused ortho-quinones from regioselective Diels–Alder reaction: Synthesis and cytotoxicity evaluation
Fulltext Access 7 Pages 2009
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