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Daneshyari Molecular Medicine Journas Latest Articles

Molecular Medicine Research Articles

Cytokines and lipopolysaccharides induce inducible nitric oxide synthase but not enzyme activity in adult rat cardiomyocytes
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Epigenetic silencing of SOD2 by histone modifications in human breast cancer cells
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Decreased expression of peroxiredoxin 6 in a mouse model of ethanol consumption
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Increased oxidation, glycoxidation, and lipoxidation of brain proteins in prion disease
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Maternally transmitted milk containing recombinant human catalase provides protection against oxidation for mouse offspring during lactation
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As(III) inhibits ultraviolet radiation-induced cyclobutane pyrimidine dimer repair via generation of nitric oxide in human keratinocytes
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Doxorubicin increases the susceptibility of brain mitochondria to Ca2+-induced permeability transition and oxidative damage
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The mitochondrial thioredoxin system regulates nitric oxide-induced HIF-1α protein
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WR-1065, the active metabolite of amifostine, mitigates radiation-induced delayed genomic instability
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Oxidative and nitrative protein modifications in Parkinson's disease
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Strategic targets to induce neovascularization by resveratrol in hypercholesterolemic rat myocardium: Role of caveolin-1, endothelial nitric oxide synthase, hemeoxygenase-1, and vascular endothelial growth factor
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Dietary oxyresveratrol prevents parkinsonian mimetic 6-hydroxydopamine neurotoxicity
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Reaction between the anesthetic agent propofol and the free radical DPPH˙ in semiaqueous media: Kinetics and characterization of the products
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Detection of mitochondrial dysfunction by EPR technique in mouse model of dilated cardiomyopathy
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Dietary fructose induces a wide range of genes with distinct shift in carbohydrate and lipid metabolism in fed and fasted rat liver
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High glucose induction of DNA-binding activity of the transcription factor NFκB in patients with diabetic nephropathy
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Differential metabolic consequences of fumarate hydratase and respiratory chain defects
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TSPO over-expression increases motility, transmigration and proliferation properties of C6 rat glioma cells
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Proliferative actions of muscarinic receptors expressed in macrophages derived from normal and tumor bearing mice
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Parameters of oxidative stress are present in the circulation of PXE patients
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Latrunculin B facilitates Shiga toxin 1 transcellular transcytosis across T84 intestinal epithelial cells
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Calcium-sensing receptor antagonism or lithium treatment ameliorates aminoglycoside-induced cell death in renal epithelial cells
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Impairment of endothelial nitric oxide synthase causes abnormal fat and glycogen deposition in liver
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Reduction of inflammation and chronic tissue damage by omega-3 fatty acids in fat-1 transgenic mice with pancreatitis
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ATP depletion alters the mode of cell death induced by benzyl isothiocyanate
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Whole-body biodistribution and radiation dosimetry in monkeys and humans of the phosphodiesterase 4 radioligand [11C](R)-rolipram: comparison of two-dimensional planar, bisected and quadrisected image analyses
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Ubiquitin and ubiquitin-like specific proteases targeted by infectious pathogens: Emerging patterns and molecular principles
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Is malfunction of the ubiquitin proteasome system the primary cause of α-synucleinopathies and other chronic human neurodegenerative disease?
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Evaluation of novel bifunctional chelates for the development of Cu-64-based radiopharmaceuticals
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What to consider in the development of new bone seekers: mechanistic and tracer-related aspects
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Biodistribution and tumor imaging of an anti-CEA single-chain antibody–albumin fusion protein
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A clinical overview of pheochromocytomas/paragangliomas and carcinoid tumors
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Anesthesia condition for 18F-FDG imaging of lung metastasis tumors using small animal PET
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In vitro and in vivo studies with [18F]fluorocholine on digestive tumoral cell lines and in an animal model of metastasized endocrine tumor
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A novel gallium bisaminothiolate complex as a myocardial perfusion imaging agent
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Improved synthesis and metabolic stability analysis of the dopamine transporter ligand [18F]FECT
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Feasibility studies of 4′-[methyl-11C]thiothymidine as a tumor proliferation imaging agent in mice
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Evaluation of [11C]rofecoxib as PET tracer for cyclooxygenase 2 overexpression in rat models of inflammation
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Synthesis and biological evaluation of helicid analogues as novel acetylcholinesterase inhibitors
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Self-regulatory role of 4-hydroxynonenal in signaling for stress-induced programmed cell death
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Roles of nitric oxide in inflammatory downregulation of human cytochromes P450
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Comparison of two Mn porphyrin-based mimics of superoxide dismutase in pulmonary radioprotection
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Endogenous DNA damage clusters in human hematopoietic stem and progenitor cells
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A formation mechanism for 8-hydroxy-2′-deoxyguanosine mediated by peroxidized 2′-deoxythymidine
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A pulse-radiolysis approach to fast reductive cleavage of a disulfide bond to uncage enzyme activity
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Commonalities of genetic resistance to spontaneous autoimmune and free radical-mediated diabetes
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Blockade of neuronal nitric oxide synthase reduces cone cell death in a model of retinitis pigmentosa
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Decreased pulmonary extracellular superoxide dismutase during systemic inflammation
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Serotonin-mediated protein carbonylation in the right heart
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Curcumin protects cardiac cells against ischemia-reperfusion injury: effects on oxidative stress, NF-κB, and JNK pathways
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Synthesis, characterization and biological activity of Pt(II) and Pt(IV) complexes with 5-methyl-5(4-pyridyl)-2,4-imidazolidenedione
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Synthesis of new substituted azetidinoyl and thiazolidinoyl-1,3,4-thiadiazino (6,5-b) indoles as promising anti-inflammatory agents
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Synthesis and anticancer activity of new class of bisphosphonates/phosphanamidates
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Antimycobacterial activity of diphenylpyraline derivatives
Fulltext Access 8 Pages 2008
Synthesis, antimicrobial and anti-inflammatory activities of some 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles and 1,2,4-triazolo[3,4-b][1,3,4]thiadiazines bearing trichlorophenyl moiety
Fulltext Access 8 Pages 2008
Epimers of bicyclo[2.2.2]octan-2-ol derivatives with antiprotozoal activity
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New amido derivatives as potential BKCa potassium channel activators. XI
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Synthesis and in vivo anti-mutagenic activity of novel melatonin derivatives
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Synthesis and antiproliferative activities of isoindigo and azaisoindigo derivatives
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Preparation and characterization of technetium and rhenium tricarbonyl complexes bearing the 4-nitrobenzyl moiety as potential bioreductive diagnostic radiopharmaceuticals. In vitro and in vivo studies
Fulltext Access 8 Pages 2008
Synthesis of 2,6-diaryl-substituted pyridines and their antitumor activities
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Graphical contents list
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Oxoisoaporphine alkaloid derivatives: Synthesis, DNA binding affinity and cytotoxicity
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Synthesis and biological evaluation of aminomethylphenol derivatives as inhibitors of the murine GABA transporters mGAT1–mGAT4
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Synthesis and antimicrobial activity of novel sulfone-linked bis heterocycles
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Graphical contents list
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Organotin(IV) complexes of 2-pyridineformamide-derived thiosemicarbazones: Antimicrobial and cytotoxic effects
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Graphical contents list
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NSAIDs revisited: Putative molecular basis of their interactions with peroxisome proliferator-activated gamma receptor (PPARγ)
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Synthesis and structure–activity relationship of 3-phenylquinoxaline 1,4-di-N-oxide derivatives as antimalarial agents
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Synthesis, characterization and antibacterial activity of cobalt(III) complexes with pyridine–amide ligands
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Synthesis and antimicrobial activity of some new heterocycles incorporating antipyrine moiety
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Analysis of the saliva proteome from patients with head and neck squamous cell carcinoma reveals differences in abundance levels of proteins associated with tumour progression and metastasis
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Assessing CMT cell line stability by two dimensional polyacrylamide gel electrophoresis and mass spectrometry based proteome analysis
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Identification of dominant signaling pathways from proteomics expression data
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Graphical contents list
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QSAR analysis of PPAR-γ agonists as anti-diabetic agents
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Graphical contents list
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New glycosidic derivatives of histidine-containing dipeptides with antioxidant properties and resistant to carnosinase activity
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Anti-tumor 12-deoxyphorbol esters from Euphorbia cornigera
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Graphical contents list
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Synthesis and antiproliferative activity of aryl- and heteroaryl-hydrazones derived from xanthone carbaldehydes
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Synthesis and biological activities of a series of 4,5-diaryl-3-hydroxy-2(5H)-furanones
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The novel primaquine derivatives of N-alkyl, cycloalkyl or aryl urea: Synthesis, cytostatic and antiviral activity evaluations
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Investigations concerning the COX/5-LOX inhibiting and hydroxyl radical scavenging potencies of novel 4,5-diaryl isoselenazoles
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Graphical contents list
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Synthesis, characterization, antioxidant activity and DNA-binding studies of two rare earth(III) complexes with naringenin-2-hydroxy benzoyl hydrazone ligand
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Preparation and antibacterial activity of cyclic 2′,3′-carbamate derivatives of azithromycin
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EuPA achieves visibility — An activity report on the first three years
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QSAR study of neuraminidase inhibitors based on heuristic method and radial basis function network
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New stereoselective titanium reductive amination synthesis of 3-amino and polyaminosterol derivatives possessing antimicrobial activities
Fulltext Access 8 Pages 2008
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs
Fulltext Access 8 Pages 2008
Synthesis and biological evaluation of some thiazolyl and thiadiazolyl derivatives of 1H-pyrazole as anti-inflammatory antimicrobial agents
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Novel linear triaryl guanidines, N-substituted guanidines and potential prodrugs as antiprotozoal agents
Fulltext Access 8 Pages 2008
Indanesulfonamides as carbonic anhydrase inhibitors and anticonvulsant agents: Structure–activity relationship and pharmacological evaluation
Fulltext Access 8 Pages 2008
2,3,5-Substituted tetrahydrofurans: COX-2 inhibitory activities of 5-hydroxymethyl-/carboxyl-2,3-diaryl-tetrahydro-furan-3-ols
Fulltext Access 8 Pages 2008
CoMFA analysis of dual/multiple PPAR activators
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Synthesis, chemical and biological studies on new Fe3+-glycosilated β-diketo complexes for the treatment of iron deficiency
Fulltext Access 8 Pages 2008
Synthesis, structure, antimicrobial and antioxidant investigations of dicoumarol and related compounds
Fulltext Access 8 Pages 2008
Synthesis and evaluation of a series of benzopyran derivatives as PPAR α/γ agonists
Fulltext Access 8 Pages 2008
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