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Daneshyari Drug Discovery Journas Latest Articles

Drug Discovery Research Articles

Regio- and stereocontrolled synthesis and conformational analysis of benzimidazole nucleosides
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Synthesis and characterization of new trinitrofluorene-fullerene dyads as photosensitizers in photorefractive polymer materials. Redox behavior and charge-transfer properties
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Selenium-catalyzed oxidative halogenation
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Direct organocatalytic enantioselective α-aminomethylation of ketones
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l-Proline catalysed asymmetric aldol reactions in PEG-400 as recyclable medium and transfer aldol reactions
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Graphical contents list
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Modular synthesis of chiral pentadentate bis(oxazoline) ligands
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Clay-anchored non-heme iron-salen complex catalyzed cleavage of CC bond in aqueous medium
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[1,2]-Wittig rearrangement from chloromethyl ethers
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Studies on quinones. Part 40: Synthesis and cytotoxicity evaluation of anthraquinone epoxides and isomerization products
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Synthesis of methylenecyclopropane analogues of antiviral nucleoside phosphonates
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Experimental and theoretical study on the substitution reactions of aryl 2,4-dinitrophenyl carbonates with quinuclidines
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Hydroxyl ionic liquid (HIL)-immobilized quinuclidine for Baylis-Hillman catalysis: synergistic effect of ionic liquids as organocatalyst supports
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Dendritic liquid-crystalline fullerene-ferrocene dyads
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Formation of metal-lustrous organic crystals from 2-aryl-1-(4-methoxyphenyl)-5-(5-tricyanoethenyl-2-thienyl)pyrroles
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General method of obtaining deuterium-labeled heterocyclic compounds using neutral D2O with heterogeneous Pd/C
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Synthesis of a β-strand mimetic based on a pyridine scaffold
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Pd(OAc)2/DABCO-catalyzed Suzuki-Miyaura cross-coupling reaction in DMF
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Palladium-catalyzed syntheses of tetrahydrocarbazolones as advanced intermediates to carbazole alkaloids
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A computational study of halomethyllithium carbenoid mixed aggregates with lithium halides and lithium methoxide
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Tetrahedron reports on organic chemistry author index
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New active-iron based reducing system for carbonyl compounds and imines. Stereoselective reduction of cyclic ketones
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Aziridines derived from amino acids as synthons in pseudopeptide synthesis
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[2+2] Cycloaddition of ketenes with ynamides. A general method for the synthesis of 3-aminocyclobutenone derivatives
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Photoinduced electron-transfer systems consisting of electron-donating pyrenes or anthracenes and benzimidazolines for reductive transformation of carbonyl compounds
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Synthesis of 2′-dealkylmumbaistatin
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Graphical contents list
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Structure and stereochemistry of the monobromotigogenins
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Chemistry of biureas-I
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Synthesis of Optically Active 9-Oxabicyclo[3.3.1]nona-2,6-diene as a Cycloocta-1,5-diene Equivalent and the Corresponding Tetrol
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Novel bifluorene based conjugated systems: synthesis and properties
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Diastereoselective reduction of enantiopure N-p-toluenesulfinyl ketimines derived from pyridyl ketones
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Silylated β-enaminones as precursors in the regioselective synthesis of silyl pyrazoles
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Synthesis, properties and molecular structure of a novel dicyanoheptafulvene derivative, 4′-dicyanomethylidenedispiro[cyclohexane-1, 1′-(1′,4′,7′-trihydrocyclopenta[f]azulene)-7′,1″-cyclohexane]
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Development of water-soluble far-red fluorogenic dyes for enzyme sensing
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New cyclic depsipeptides from the green alga Bryopsis species; application of a carboxypeptidase hydrolysis reaction to the structure determination
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Remote stereocontrol by sulfinyl groups: hydrocyanation of δ-ketosulfoxides
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Synthesis and rotational barriers of atropisomers of 1,2-bis[5-(11H-benzo[b]fluorenyl)]benzenes and related compounds
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C-S bond cleavage in the sensitized photooxygenation of tert-alkyl phenyl sulfides. The role of superoxide anion
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Synthesis and cation binding properties of new arylazo- and heteroarylazotetrathiacalix[4]arenes
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Photoinduced cycloadditions of N-methyl-1,8-naphthalenedicarboximides with alkynes
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Synthesis of dipyrrolo[3,4-a:3,4-c]carbazole-1,3,4,6-tetraones bearing a sugar moiety
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Stereochemical revision of communiols D and H through synthesis
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3-Aza-8,10-dioxa-bicyclo[5.2.1]decane (9-exo BTKa) carboxylic acid as a new reverse turn inducer: synthesis and conformational analysis of a model peptide
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Tricalysiolides A-F, new rearranged ent-kaurane diterpenes from Tricalysia dubia
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1,3-Dipolar cycloaddition approach to isoxazole, isoxazoline and isoxazolidine analogues of C-nucleosides related to pseudouridine
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Stable chiral spirocyclic [5,5]-ammonium ylides using a metallo carbenoid approach
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New fluorinated 1,3-vinylogous amidines as versatile intermediates: synthesis of fluorinated pyrimidin-2(1H)-ones
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Regioselective electrophilic substitutions of fulvenes with ethyl glyoxylate and subsequent Diels-Alder reactions
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Lewis and protic acid mediated Nicholas reactions of 3-acetoxycyclohept-1-en-4-ynedicobalt hexacarbonyl: site selectivity of nucleophile incorporation
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Meningococcal diseases: From genomes to vaccines
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Novel 24-nor-, 24-nor-2,3-seco-, and 3,24-dinor-2,4-seco-ursane triterpenes from Diospyros decandra: evidences for ring A biosynthetic transformations
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A DFT study of the Diels-Alder reaction between methyl acrolein derivatives and cyclopentadiene. Understanding the effects of Lewis acids catalysts based on sulfur containing boron heterocycles
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Synthesis of calix[4]arene-cyclen conjugates
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Intramolecular electrophilic aromatic substitution of α-alkylcinnamaldehydes affording 1-alkoxy-2-alkylindenes
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Practical syntheses of penciclovir and famciclovir from N2-acetyl-7-benzylguanine
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Tetrahedron reports on organic chemistry author index
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Efficient and selective oxidation of methyl substituted cycloalkanes by heterogeneous methyltrioxorhenium-hydrogen peroxide systems
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Reactions of 3,10-epoxycyclo[10.2.2.02,11.04,9]hexadeca-4,6,8,13-tetraene: a new intramolecular 1,5-oxygen migration
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Antimicrobial peptides in skin disease
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Why do we not have a vaccine against congenital cytomegalovirus (CMV) infection?
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Can efflux inhibitors really counter resistance?
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Tigecycline: First class glycylcycline: a new choice for empiric therapy
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Synthesis of five- to seven-membered polyfunctional terpenic carbocycles via Ti(III)-catalyzed radical cyclizations of epoxypolyprenes
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Anti-inflammatory strategies for the treatment of multiple sclerosis – tryptophan catabolites may hold the key
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Chemokines and chemokine receptors: Large and small therapeutic strategies for inflammatory diseases
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Antibody treatment of ulcerative colitis
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Employment of microRNA profiles and RNA interference and antagomirs for the characterization and treatment of respiratory disease
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Toll-like receptors and airway disease
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Tumour necrosis factor-α as a therapeutic target in asthma
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Analysis of codon usage pattern in the radioresistant bacterium Deinococcus radiodurans
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DNA polymerase programmed with a hairpin DNA incorporates a multiple-instruction architecture into molecular computing
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Are organisms committed to lower their rates of entropy production?
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Global rhythmic activities in hippocampal neural fields and neural coding
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Focal adhesions as mechanosensors: The two-spring model
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Diels-Alder cycloaddition of electrophilic 2H-azirines with 3-(3-(tert-butyldimethylsilyloxy)buta-1,3-dienyl)oxazolidin-2-ones. Treatment of the cycloadducts under acidic conditions
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A computational study of solution effects on the disproportionation of electrochemically generated polycyclic aromatic hydrocarbon radical anions. Thermodynamics and structure
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Pd/C-Et3N-mediated catalytic hydrodechlorination of aromatic chlorides under mild conditions
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Synthesis of tetra-oligothiophene-substituted calix[4]arenes and their optical and electrochemical properties
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Synthesis of N-alkyl substituted bioactive indolocarbazoles related to Gö6976
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A brief and stereoselective synthesis of limonoid models, with antifeedant activity against Locusts migratoria
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A novel series of oligomers from 4-aminomethyl-tetrahydrofuran-2-carboxylates with 2,4-cis and 2,4-trans stereochemistry
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Synthesis of 2-oxo-2,3,5,6-tetrahydro-5-thioxoimidazo[1,2-c]quinazolines by one-pot cyclization of α-aminocarboxylic esters with 2-(isothiocyanato)benzonitrile (ITCB)
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Generation and trapping of tricyclo[3.3.0.03,7]oct-1(5)-ene derivatives containing carbonyl functionalities
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Arene-promoted lithiation of 1,n-dihaloalkanes (n=2-6): a comparative study
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A direct efficient diastereoselective synthesis of enantiopure 3-substituted-isobenzofuranones
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Synthesis of 2-ferrocenylidene-4-cyclopentene-1,3-diones
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Syntheses of new functionalized azobenzenes for potential molecular electronic devices
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Spatiotemporal chemical dynamics in living cells: From information trafficking to cell physiology
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Synthesis, NMR characterization and ion binding properties of 1,3-bridged p-tert-butyldihomooxacalix[4]crown-6 bearing pyridyl pendant groups
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Chemical constituents of Ligularia virgaurea and its diversity in southwestern Sichuan of China
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Synthesis of Δ2-OPC-8:0 and OPC-6:0
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A tandem multi-component synthesis of 5,7-diaryl-5,6,7,8-tetrahydro-1H-pyrido[3,4-b][1,4]thiazin-2(3H)-ones
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An MO study of regioselective amine addition to ortho-quinones relevant to melanogenesis
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Palladium-catalysed intramolecular enolate O-arylation and thio-enolate S-arylation: synthesis of benzo[b]furans and benzo[b]thiophenes
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Deracemisation of β-hydroxy esters using immobilised whole cells of Candida parapsilosis ATCC 7330: substrate specificity and mechanistic investigation
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Synthesis of 8-heteroatom-substituted 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene dyes (BODIPY)
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Cellular routines in the synthesis of cyclic peptide probes
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Formal synthesis of Abyssomicin C
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Dihedral angle restriction within a peptide-based tertiary alcohol kinetic resolution catalyst
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