There and back again: Autoimmune Polyendocrinopathy Syndrome Type I and the Aire knockout mouse Fulltext Access 8 Pages 2006
Retinoids and pulmonary alveolar regeneration: Rationale and therapeutic challenges Fulltext Access 8 Pages 2006
Mutations in the sodium channel Nav1.7 underlie inherited erythromelalgia Fulltext Access 8 Pages 2006
Medullary control of nociceptive transmission: Reciprocal dual communication with the spinal cord Fulltext Access 8 Pages 2006
The accessory gene regulator (agr) in methicillin-resistant Staphylococcus aureus: Role in virulence and reduced susceptibility to glycopeptide antibiotics Fulltext Access 8 Pages 2006
Underlying mechanisms of hematologic malignancies revealed by gene expression profiling Fulltext Access 8 Pages 2006
Drosophila models pioneer a new approach to drug discovery for Parkinson's disease Fulltext Access 8 Pages 2006
Complementary molecular imaging technologies: High resolution SPECT, PET and MRI Fulltext Access 8 Pages 2006
Emerging pharmacotherapeutic strategies for the treatment of ischemic stroke Fulltext Access 8 Pages 2006
Benzodiazepine receptor agonists and insomnia: Is subtype selectivity lost in translation? Fulltext Access 8 Pages 2006
Enhancing AMPA to NMDA throughput as a convergent mechanism for antidepressant action Fulltext Access 8 Pages 2006
Development of functionally selective agonists as novel therapeutic agents Fulltext Access 8 Pages 2006
Chondrocyte genomics: implications for disease modification in osteoarthritis Fulltext Access 8 Pages 2006
Model systems for neurofibroma and malignant peripheral nerve sheath tumor Fulltext Access 8 Pages 2006
Surgical models of hypertrophy and heart failure: Myocardial infarction and transverse aortic constriction Fulltext Access 8 Pages 2006
An efficient route for the synthesis of methyl (−)-1,4a-dimethyl-5-oxodecahydronaphthalene-1-carboxylate by using baker’s yeast-catalyzed asymmetric reduction Fulltext Access 8 Pages 2006
A DFT study of the geometric, magnetic NMR chemical shifts and optical rotation properties of Tröger’s bases Fulltext Access 8 Pages 2006
Selectivity enhancement of enantio- and stereo-complementary epoxide hydrolases and chemo-enzymatic deracemization of (±)-2-methylglycidyl benzyl ether Fulltext Access 8 Pages 2006
Novel preparation of (−)-4-hydroxycyclohex-2-enone: reaction of 4-hydroxycyclohex-2-enone and 4-hydroxycyclopent-2-enone with some thiols Fulltext Access 8 Pages 2006
Solid-state reshaping of nanostructured crystals: supramolecular chirality of layered materials derived from polyethylenoxa-pillared zirconium phosphate Fulltext Access 8 Pages 2006
Chemoenzymatic synthesis of (3R,4S)- and (3S,4R)-3-methoxy-4-methylaminopyrrolidine Fulltext Access 8 Pages 2006
Ruthenium- and lipase-catalyzed DYKAT of 1,2-diols: an enantioselective synthesis of syn-1,2-diacetates Fulltext Access 8 Pages 2006
Preparation and application of bisoxazoline ligands with a chiral spirobiindane skeleton for asymmetric cyclopropanation and allylic oxidation Fulltext Access 8 Pages 2006
Studies on Cu-catalyzed asymmetric alkynylation of tetrahydroisoquinoline derivatives Fulltext Access 8 Pages 2006
Catalytic asymmetric cyano-phosphorylation of aldehydes using a YLi3tris(binaphthoxide) complex (YLB) Fulltext Access 8 Pages 2006
Dendritic MonoPhos: synthesis and application in Rh-catalyzed asymmetric hydrogenation Fulltext Access 8 Pages 2006
Synthesis of chiral ligands containing the N-(S)-α-phenylethyl group and their evaluation as activators in the enantioselective addition of Et2Zn to benzaldehyde Fulltext Access 8 Pages 2006
Stereoselective synthesis of (1R,2R)-1-amino-2-hydroxycyclobutanecarboxylic acid-serine derivative-, from racemic or optically active 2-benzyloxycyclobutanone Fulltext Access 8 Pages 2006
Catalytic, asymmetric Strecker reactions catalysed by titaniumIV and vanadiumV(salen) complexes Fulltext Access 8 Pages 2006
Asymmetric reduction of substituted indanones and tetralones catalyzed by chiral dendrimer and its application to the synthesis of (+)-sertraline Fulltext Access 8 Pages 2006
Synthesis of enantiomerically pure β,β-diphenylalanine (Dip) and fluorenylglycine (Flg) Fulltext Access 8 Pages 2006
Interaction of amines with rhodium(II) tetracarboxylates in solution: formation of nitrogenous stereogenic center Fulltext Access 8 Pages 2006
Rh2[(R)-(+)-MTPA]4 as an NMR auxiliary for the enantiodifferentiation of chiral secondary and tertiary phosphine–borane complexes Fulltext Access 8 Pages 2006
Asymmetric addition of trimethylsilyl cyanide to aldehydes promoted by chiral polymeric vanadium(V) salen complex as an efficient and recyclable catalyst Fulltext Access 8 Pages 2006
Enantioselective diethylzinc addition to the exocyclic CN double bond of some 4-arylideneamino-3-mercapto-6-methyl-4H-1,2,4-triazin-5-one derivatives Fulltext Access 8 Pages 2006
Synthesis of chiral 2-furyl and 3-nitro-7-oxabicyclo[2.2.1]heptane derivatives from sugars Fulltext Access 8 Pages 2006
Rational and efficient geometric definition of pharmacophores is essential for the patent process Fulltext Access 8 Pages 2006
Blood–brain barrier genomics and proteomics: elucidating phenotype, identifying disease targets and enabling brain drug delivery Fulltext Access 8 Pages 2006
Clearance of amyloid-beta in Alzheimer's disease: progress, problems and perspectives Fulltext Access 8 Pages 2006
Stereoselective α-amidoalkylation of phenylglycinol-derived lactams. Synthesis of enantiopure 5,6-disubstituted 2-piperidones Fulltext Access 8 Pages 2006
Vector-based RNAi approaches for stable, inducible and genome-wide screens Fulltext Access 8 Pages 2006
Integrating molecular design resources within modern drug discovery research: the Roche experience Fulltext Access 8 Pages 2006
Systems biology, metabolic modelling and metabolomics in drug discovery and development Fulltext Access 8 Pages 2006
Phenomenological model of bone remodeling cycle containing osteocyte regulation loop Fulltext Access 8 Pages 2006
CLAGen: A tool for clustering and annotating gene sequences using a suffix tree algorithm Fulltext Access 8 Pages 2006
Synthesis of both RP and SP enantiomers of unsymmetrical methylphosphonates based on a new approach utilizing a P-ester bond with α-hydroxyacids Fulltext Access 8 Pages 2006