Essential hypertension seems to result from melatonin-induced epigenetic modifications in area postrema Fulltext Access 8 Pages 2006
2-Aminoethoxydiphenyl borate (2-APB) stimulates a conformationally coupled calcium release pathway in the NG115-401L neuronal cell line Fulltext Access 8 Pages 2006
Serotonin 2A receptor antagonist treatment reduces dopamine D1 receptor-mediated rotational behavior but not l-DOPA-induced abnormal involuntary movements in the unilateral dopamine-depleted rat Fulltext Access 8 Pages 2006
meso-Dihydroguaiaretic acid attenuates the neurotoxic effect of staurosporine in primary rat cortical cultures Fulltext Access 8 Pages 2006
Enhancement of the analgesic activity of paracetamol and nitroparacetamol by the oral administration of all-trans retinoic acid Fulltext Access 8 Pages 2006
Retigabine-induced population primary afferent hyperpolarisation in vitro Fulltext Access 8 Pages 2006
Identification of residues critical for Cu2+-mediated inhibition of glycine α1 receptors Fulltext Access 8 Pages 2006
Cyclosporin A inhibits apolipoprotein A-I-induced early events in cellular cholesterol homeostasis in rat astrocytes Fulltext Access 8 Pages 2006
Molecular mechanisms mediating gastrin-releasing peptide receptor modulation of memory consolidation in the hippocampus Fulltext Access 8 Pages 2006
The enantiomer of progesterone acts as a molecular neuroprotectant after traumatic brain injury Fulltext Access 8 Pages 2006
Presynaptic inhibition by kainate receptors converges mechanistically with presynaptic inhibition by adenosine and GABAB receptors Fulltext Access 8 Pages 2006
Distinct endocrine effects of chronic haloperidol or risperidone administration in male rats Fulltext Access 8 Pages 2006
Anti-inflammatory properties of cholinergic up-regulation: A new role for acetylcholinesterase inhibitors Fulltext Access 8 Pages 2006
The human stratum corneum as extended, covalently cross-linked biopolymer: Mathematics, molecules, and medicine Fulltext Access 8 Pages 2006
Atrial fibrillation in athletes: Implicit literature-based connections suggest that overtraining and subsequent inflammation may be a contributory mechanism Fulltext Access 8 Pages 2006
PKC-mediated modulation of L-type calcium channels may contribute to fat-induced insulin resistance Fulltext Access 8 Pages 2006
Contrast nephropathy may be partly mediated by autonomic dysfunction: Renal failure considered as a modern maladaptation of the prehistoric trauma response Fulltext Access 8 Pages 2006
Possible interactions of genetic and immuno-neuro-endocrine regulatory mechanisms in pathogenesis of congenital anomalies Fulltext Access 8 Pages 2006
Evolutionary neuropathology and Down syndrome: An analysis of the etiological and phenotypical characteristics of Down syndrome suggests that it may represent an adaptive response to severe maternal deprivation Fulltext Access 8 Pages 2006
Fractionated radioimmunotherapy of intraperitoneally growing ovarian cancer in nude mice with 211At-MX35 F(ab′)2: therapeutic efficacy and myelotoxicity Fulltext Access 8 Pages 2006
Efficient inefficiency: Biochemical “junk” may represent molecular bridesmaids awaiting emergent function as a buffer against environmental fluctuation Fulltext Access 8 Pages 2006
A model of peripherally developing hearing loss and tinnitus based on the role of hypoxia and ischemia Fulltext Access 8 Pages 2006
Endocannabinoids at the spinal level regulate, but do not mediate, nonopioid stress-induced analgesia Fulltext Access 8 Pages 2006
Accessibility to residues in transmembrane segment four of the glycine receptor Fulltext Access 8 Pages 2006
Enhanced nicotinic acetylcholine receptor-mediated [3H]norepinephrine release from neonatal rat hypothalamus Fulltext Access 8 Pages 2006
The locus coeruleus nucleus as a site of action of the antinociceptive and behavioral effects of the nicotinic receptor agonist, epibatidine Fulltext Access 8 Pages 2006
Injection of l-glutamate into medial prefrontal cortex induces cardiovascular responses through NMDA receptor – nitric oxide in rat Fulltext Access 8 Pages 2006
In vivo effect of tramadol on locus coeruleus neurons is mediated by α2-adrenoceptors and modulated by serotonin Fulltext Access 8 Pages 2006
Selective changes in thalamic and cortical GABAA receptor subunits in a model of acquired absence epilepsy in the rat Fulltext Access 8 Pages 2006
3-Hydroxypyridazine 1-oxides as carboxylate bioisosteres: A new series of subtype-selective AMPA receptor agonists Fulltext Access 8 Pages 2006
Effects of chronic nicotine administration and its withdrawal on striatal FosB/ΔFosB and c-Fos expression in rats and mice Fulltext Access 8 Pages 2006
Mu opioid receptor-dependent and independent components in effects of tramadol Fulltext Access 8 Pages 2006
Analgesic effects of mGlu1 and mGlu5 receptor antagonists in the rat formalin test Fulltext Access 8 Pages 2006
Orexin A affects ascending contraction depending on downstream cholinergic neurons and descending relaxation through independent pathways in mouse jejunum Fulltext Access 8 Pages 2006
What frontotemporal dementia reveals about the neurobiological basis of morality Fulltext Access 8 Pages 2006
The N-terminus of the norepinephrine transporter regulates the magnitude and selectivity of the transporter-associated leak current Fulltext Access 8 Pages 2006
Blockade of intracellular calcium release induces an antidepressant-like effect in the mouse forced swimming test Fulltext Access 8 Pages 2006
In vitro and ex vivo distribution of [3H]harmane, an endogenous β-carboline, in rat brain Fulltext Access 8 Pages 2006
An NMDA receptor-dependent hydroxyl radical pathway in the rabbit hypothalamus may mediate lipopolysaccharide fever Fulltext Access 8 Pages 2006
Effects of histamine H3 antagonists and donepezil on learning and mnemonic deficits induced by pentylenetetrazol kindling in weanling mice Fulltext Access 8 Pages 2006
Adenylyl cyclase type II activity is regulated by two different mechanisms: Implications for acute and chronic opioid exposure Fulltext Access 8 Pages 2006
l-3,4-Dihydroxyphenylalanine-induced c-Fos expression in the CNS under inhibition of central aromatic l-amino acid decarboxylase Fulltext Access 8 Pages 2006
The GABAB receptor allosteric modulator CGP7930, like baclofen, reduces operant self-administration of ethanol in alcohol-preferring rats Fulltext Access 8 Pages 2006
The acetylcholinesterase inhibitor, Donepezil, regulates a Th2 bias in Alzheimer's disease patients Fulltext Access 8 Pages 2006
Regional and cellular distribution of CYP2E1 in monkey brain and its induction by chronic nicotine Fulltext Access 8 Pages 2006
Target ability and therapy efficacy of immunoliposomes using a humanized antihepatoma disulfide-stabilized Fv fragment on tumor cells Fulltext Access 8 Pages 2006
A process analytical technology approach based on near infrared spectroscopy: Tablet hardness, content uniformity, and dissolution test measurements of intact tablets Fulltext Access 8 Pages 2006
High throughput solubility measurement with automated polarized light microscopy analysis Fulltext Access 8 Pages 2006
Effects of Deaeration Methods on Dissolution Testing in Aqueous Media: A Study Using a Total Dissolved Gas Pressure Meter* Fulltext Access 8 Pages 2006
In Situ Measurement of Solvent-Mediated Phase Transformations During Dissolution Testing Fulltext Access 8 Pages 2006
Effects of Cyclodextrins on Chemically and Thermally Induced Unfolding and Aggregation of Lysozyme and Basic Fibroblast Growth Factor Fulltext Access 8 Pages 2006
Degradation Rate of Lyophilized Insulin, Exhibiting an Apparent Arrhenius Behavior around Glass Transition Temperature Regardless of Significant Contribution of Molecular Mobility Fulltext Access 8 Pages 2006
Contribution of lysosomes to concentrative uptake of DX-9065a into rat liver Fulltext Access 8 Pages 2006
Permeation of 4-Cyanophenol and Methyl Paraben from Powder and Saturated Aqueous Solution through Silicone Rubber Membranes and Human Skin Fulltext Access 8 Pages 2006
Pharmacokinetics and Hepatic Extraction of Recombinant Human Parathyroid Hormone, hPTH (1-34), in Rat, Dog, and Monkey Fulltext Access 8 Pages 2006
Gastrointestinal transit and mucoadhesive characteristics of complexation hydrogels in rats Fulltext Access 8 Pages 2006
Acid decomposition of omeprazole in the absence of thiol: A differential pulse polarographic study at the static mercury drop electrode (SMDE) Fulltext Access 8 Pages 2006
Molecular mobility of nifedipineâPVP and phenobarbitalâPVP solid dispersions as measured by 13C-NMR spin-lattice relaxation time Fulltext Access 8 Pages 2006
Biorelevant dissolution media: Aggregation of amphiphiles and solubility of estradiol Fulltext Access 8 Pages 2006
Towards characterization and identification of solid state pharmaceutical mixtures through second harmonic generation Fulltext Access 8 Pages 2006
Quantitative determination of amorphous cyclosporine in crystalline cyclosporine samples by Fourier transform infrared spectroscopy Fulltext Access 8 Pages 2006
Injectable formulation of disodium 1-[2-(carboxylato)pyrrolidin-1-yl]diazen-1-ium-1,2-diolate (PROLI/NO), an ultrafast nitric oxide donor prodrug Fulltext Access 8 Pages 2006
A rabbit model for sublingual drug delivery: Comparison with human pharmacokinetic studies of propranolol, verapamil and captopril Fulltext Access 8 Pages 2006
Contrôle qualité des préparations hospitalières : bilan de la productionde gélules d'un hôpital pédiatrique Fulltext Access 8 Pages 2006
Adoptive immunotherapy of cancer using effector lymphocytes redirected with antibody specificity Fulltext Access 8 Pages 2006
Synthesis and evaluation of 4-[18F]fluorothalidomide for the in vivo studies of angiogenesis Fulltext Access 8 Pages 2006
In vitro metabolism studies of 18F-labeled 1-phenylpiperazine using mouse liver S9 fraction Fulltext Access 8 Pages 2006
Thermodynamic modeling of activity coefficient and prediction of solubility: Part 1 predictive models Fulltext Access 8 Pages 2006
Pedophilia: The problem with diagnosis and limitations of CBT in treatment Fulltext Access 8 Pages 2006
An hypothesis about genome structures in mammalian polyploid cells based on a new concept that genome is fractal of six hierarchies Fulltext Access 8 Pages 2006
The role of HLA-G in cytokine homeostasis during early pregnancy complicated with maternal infections: A novel etiopathological approach to the neurodevelopmental understanding of schizophrenia Fulltext Access 8 Pages 2006
The role of excessive volume expansion in the pathogenesis of preeclampsia Fulltext Access 8 Pages 2006
Reactive oxygen species and related haem pathway components as possible epigenetic modifiers in neurobehavioural pathology Fulltext Access 8 Pages 2006
The cell clone ecology hypothesis and the cell fusion model of cancer progression and metastasis: History and experimental support Fulltext Access 8 Pages 2006
The future of selective serotonin reuptake inhibitors (SSRIs) in psychiatric treatment Fulltext Access 8 Pages 2006
Genomic evidence for antibiotic resistance genes of actinomycetes as origins of antibiotic resistance genes in pathogenic bacteria simply because actinomycetes are more ancestral than pathogenic bacteria Fulltext Access 8 Pages 2006
Preliminary Evaluation of Polymer-Based Drug Composite Microparticle Production by Coacervate Desolvation with Supercritical Carbon Dioxide Fulltext Access 8 Pages 2006
Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Amitriptyline Hydrochloride* Fulltext Access 8 Pages 2006
Therapeutic utility of a novel tight junction modulating peptide for enhancing intranasal drug delivery Fulltext Access 8 Pages 2006
In Vivo use of the P450 inactivator 1-aminobenzotriazole in the rat: Varied dosing route to elucidate gut and liver contributions to first-pass and systemic clearance Fulltext Access 8 Pages 2006
Investigation of the absorption mechanisms of baicalin and baicalein in rats Fulltext Access 8 Pages 2006
Transport of levovirin prodrugs in the human intestinal Caco-2 cell line Fulltext Access 8 Pages 2006
Bioavailability and in Vivo Release Behavior of Controlled-Release Multiple-Unit Theophylline Dosage Forms in Beagle Dogs, Cynomolgus Monkeys, and Göttingen Minipigs Fulltext Access 8 Pages 2006
Immunoglobulin G has a role for systemic protein modulation in vivo: A new concept of protein homeostasis Fulltext Access 8 Pages 2006
Endogenous activation of nicotinic receptors underlies sympathetic tone generation in neonatal rat spinal cord in vitro Fulltext Access 9 Pages 2006
Acute administration of 3-nitropropionic acid, a reactive oxygen species generator, boosts ethanol-induced locomotor stimulation. New support for the role of brain catalase in the behavioural effects of ethanol Fulltext Access 9 Pages 2006
Effects of NAAG peptidase inhibitor 2-PMPA in model chronic pain – relation to brain concentration Fulltext Access 9 Pages 2006
Analgesic effects of serotonergic, noradrenergic or dual reuptake inhibitors in the carrageenan test in rats: Evidence for synergism between serotonergic and noradrenergic reuptake inhibition Fulltext Access 9 Pages 2006
Effects of flufenamic acid on fictive locomotion, plateau potentials, calcium channels and NMDA receptors in the lamprey spinal cord Fulltext Access 9 Pages 2006
Platelet-activating factor antagonists protect amyloid-β damaged neurons from microglia-mediated death Fulltext Access 9 Pages 2006